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Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Two uveitis drugs perform similarly in a head-to-head clinical trial

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S.

11 Sep 2019

Drug combination could improve survival of lung transplant patients

Lung transplantation can prolong the lives of patients with end-stage lung disease, but the median survival rate after lung transplant is less than six years, which has improved only slightly in recent decades.

28 Aug 2019

Oral steroid use in patients with inflammatory diseases increases risk of infection

Oral steroid use in patients with the inflammatory diseases polymyalgia rheumatica and/or giant cell arteritis significantly increased the risk of infection, and the risk increased with higher doses, found a study in CMAJ.

24 Jun 2019

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

The results of a randomized controlled trial presented today at the Annual European Congress of Rheumatology demonstrate high levels of treatment success in approximately two thirds of patients despite tapered glucocorticoid discontinuation, while a small loss of disease control was observed at the total study population level.

13 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Study provides new insight into how obesity, insulin resistance can affect cognition

Obesity can break down our protective blood brain barrier resulting in problems with learning and memory, scientists report.

22 Apr 2019

Study findings hold promise for children with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects.

11 Feb 2019

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

Most patients with ulcerative colitis have mild-to-moderate disease characterized by periods of activity or remission, but practice variations exist in disease management.

10 Jan 2019

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

First biosimilar approved by FDA for treatment of adult patients with non-Hodgkin’s lymphoma

The U.S. Food and Drug Administration today approved Truxima (rituximab-abbs) as the first biosimilar to Rituxan (rituximab) for the treatment of adult patients with CD20-positive, B-cell non-Hodgkin's lymphoma (NHL) to be used as a single agent or in combination with chemotherapy.

29 Nov 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended broadening the existing marketing authorization for Darzalex® for use as frontline therapy.

28 Jul 2018

Prednisone News and Research

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Two uveitis drugs perform similarly in a head-to-head clinical trial

Drug combination could improve survival of lung transplant patients

Oral steroid use in patients with inflammatory diseases increases risk of infection

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Study provides new insight into how obesity, insulin resistance can affect cognition

Study findings hold promise for children with DMD

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

Potential combination therapy against rare disease of the bone marrow could improve treatment

First biosimilar approved by FDA for treatment of adult patients with non-Hodgkin’s lymphoma

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

African-American men with prostate cancer show stronger response to hormone therapy

Study: People taking immunosuppressant drugs less likely to develop Parkinson's disease

Researchers find new method to treat severe asthma

Eczema drug alleviates asthma symptoms and improves lung function

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Poison ivy and poison oak can cause mild to severe allergic reactions

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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