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Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

Natural products to be developed as anti-cancer therapeutics

The licence grants Zentaris exclusive worldwide rights for the development, manufacture and marketing of disorazoles, a novel class of natural products with strong anti-cancer potential discovered by GBF researchers.

8 Jul 2004

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined that a particular type of cellular stress called osmotic stress is of critical importance to cell growth and the body’s immune response against infection.

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Convincing evidence that at dietary levels, the estrogens found in soy do not stimulate cell growth and other markers for cancer risk

New research in monkeys suggests that a diet high in the natural plant estrogens found in soy does not increase the risk of breast or uterine cancer in postmenopausal women.

7 Jul 2004

Protein controls acid in cells by direct detection of volume changes

A protein responsible for regulating acid levels within cells - and pumping out acid accumulated in cardiac cells after a heart attack - activates in direct response to changes in a cell's volume, according to a new study by researchers at UT Southwestern Medical Center at Dallas.

5 Jul 2004

Chemicals that inhibit the development of new blood vessels could prove to be a new way of treating endometriosis

Chemicals that inhibit the development of new blood vessels could prove to be a new way of treating endometriosis, according to research from The Netherlands and the USA presented today (Monday 28 June) at the 20th annual meeting of the European Society of Human Reproduction and Embryology.

28 Jun 2004

First-ever microfluidic BioMEMS device to study the mechanisms of cell migration and deformation

Cancer cells have the ability to invade blood vessels and find their way into the bloodstream. Once there, these infected cells can easily travel to other parts of the body and attack healthy organs.

25 Jun 2004

Discovery of a gene-expression signature common to distinct types of cancer

Researchers at the University of Michigan, Johns Hopkins and the Institute of Bioinformatics in India have discovered a gene-expression "signature" common to distinct types of cancer

23 Jun 2004

Sirolimus-based therapy following early cyclosporine withdrawal improves transplanted kidney structure and function

Kidney histology and function three years after transplantation are better in kidney-transplant patients who remain on sirolimus-based therapy following early withdrawal of cyclosporine than in patients who continue on this calcineurin inhibitor, according to a new study published in the American Journal of Transplantation.

11 Jun 2004

Crucial discovery may help better diagnose and treat children with Hirschsprung disease

Researchers at Fox Chase Cancer Center have made a crucial discovery that may help physicians better diagnose and treat children with Hirschsprung disease, a debilitating and sometimes life-threatening ailment that causes bowel obstruction and involves an array of genetic changes.

5 Jun 2004

Drinking only bottled water associated with a two-fold risk of infection

Doing laundry using hot water and bleach may prevent infections in the home, while drinking only bottled water may promote infections, according to research.

2 Jun 2004

Novel molecular targeting technologies to deliver gene-silencing therapy

Researchers have combined novel molecular targeting technologies to deliver gene-silencing therapy specifically to tumor cells shielded by a normally impermeable obstacle, the blood brain barrier.

1 Jun 2004

Randomness in gene expression to lead to differences in people that are genetically identical

Experiments by Howard Hughes Medical Institute (HHMI) researchers have revealed it might be possible for randomness in gene expression to lead to differences in cells — or people, for that matter — that are genetically identical.

27 May 2004

Possible new second-generation multiple sclerosis therapy

Scientists from Genencor International, Inc., have demonstrated in an in vivo model that a new variant of recombinant interferon-beta reduces the immunological response to the protein.

25 May 2004

New stent appears safe and effective for preventing arteries from reclosing in coronary heart disease patients

A new stent appears safe and effective for preventing arteries from reclosing in coronary heart disease patients, based on one-year results of the first human trial using this stent reported in today’s rapid access issue of Circulation: Journal of the American Heart Association.

6 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

New developments in the treatment of pancreatic cancer

A booster dose of a substance already found in the body appears to be safe and non-toxic for the treatment of pancreatic cancer, and shows signs of arresting pancreatic cancer cell growth in patients, Penn State College of Medicine researchers report.

20 Apr 2004

Wine, beer and tea have contributed to a significant decrease in breast cancer

Numerous studies have been published showing that consuming alcohol increases the risk for breast cancer. That’s what makes a new research finding from Portugal so intriguing. The study has determined that certain compounds found in wine, beer (and tea) have contributed to a significant decrease in breast cancer cell proliferation.

19 Apr 2004

New research into Human Papilloma Virus (HPV) and Cervical Cancer

Cervical cancer is the second-most prevalent cancer in women and, despite encouraging improvements in screening leading to earlier detection, cervical cancer still kills many women every year. The risk of cervical cancer is increased by infection with certain types of human papilloma virus (HPV).

12 Apr 2004

Proliferation News and Research

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

Natural products to be developed as anti-cancer therapeutics

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Convincing evidence that at dietary levels, the estrogens found in soy do not stimulate cell growth and other markers for cancer risk

Protein controls acid in cells by direct detection of volume changes

Chemicals that inhibit the development of new blood vessels could prove to be a new way of treating endometriosis

First-ever microfluidic BioMEMS device to study the mechanisms of cell migration and deformation

Discovery of a gene-expression signature common to distinct types of cancer

Sirolimus-based therapy following early cyclosporine withdrawal improves transplanted kidney structure and function

Crucial discovery may help better diagnose and treat children with Hirschsprung disease

Drinking only bottled water associated with a two-fold risk of infection

Novel molecular targeting technologies to deliver gene-silencing therapy

Randomness in gene expression to lead to differences in people that are genetically identical

Possible new second-generation multiple sclerosis therapy

New stent appears safe and effective for preventing arteries from reclosing in coronary heart disease patients

Developing smart drugs

New developments in the treatment of pancreatic cancer

Wine, beer and tea have contributed to a significant decrease in breast cancer

New research into Human Papilloma Virus (HPV) and Cervical Cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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