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Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Exploring pharmacological, non-pharmacological, and stem cell therapies for treatment of autism spectrum disorders

A research study, led by Maurizio Battino and Francesca Giampieri, with a group of researchers from the Universidad Europea del Atlántico (European University of the Atlantic, UNEATLANTICO), published in the journal "Pharmacological Research", studies various pharmacological, non-pharmacological, and stem cell therapies for the treatment of autism spectrum disorders.

27 Jan 2024

Research upends understanding of circadian clock in melanoma

A Ludwig Cancer Research study has found that the circadian clock-;which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive-;in fact has a contextually variable role in cancer.

27 Jan 2024

Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.

26 Jan 2024

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments.

24 Jan 2024

Mutations found in skin cancers could be harnessed to mend broken hearts

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

24 Jan 2024

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

Immune checkpoint inhibitor target found to promote skin cancer growth

Programmed cell death 1 (PD-1) is an important target for immune checkpoint inhibitor therapies that block its signaling and boost T-cell activity. PD-1 inhibitors have been approved for treating various types of cancer.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Antiviral hope emerges as viruses linked to multiple myeloma

A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C, astounding researchers from the group led by Joaquín Martínez, from the H12O-CNIO Haematological Tumours Clinical Research Unit, a collaboration between the Hospital 12 de Octubre (H12O) and the National Cancer Research Centre (CNIO).

19 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

RBMX protein emerges as key player in cancer progression and immunotherapy response

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response."

17 Jan 2024

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland – the very cells that specialise in milk production during and after pregnancy.

16 Jan 2024

Revolutionary brain scan lights up glioma's Achilles heel

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) made a new discovery that can revolutionize both the diagnosis and treatment of glioblastoma.

16 Jan 2024

Proliferation News and Research

Immune protein Ku70 key in fighting bowel cancer

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Exploring pharmacological, non-pharmacological, and stem cell therapies for treatment of autism spectrum disorders

Research upends understanding of circadian clock in melanoma

Sclerostin may protect against heart disease in patients with type 2 diabetes

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Mutations found in skin cancers could be harnessed to mend broken hearts

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

Immune checkpoint inhibitor target found to promote skin cancer growth

Ludwig scientists deconstruct the blood supply of brain metastases

Antiviral hope emerges as viruses linked to multiple myeloma

Annexin-A1 targeted therapy beats several cancers

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

RBMX protein emerges as key player in cancer progression and immunotherapy response

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Revolutionary brain scan lights up glioma's Achilles heel

Is AI the future of personalized hypertension risk assessment, diagnosis, and treatment?

Hundreds of chemicals linked to breast cancer risk identified in new study

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

Uncovering the role of ER-mitochondria connections in muscle atrophy

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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