Proteasome Inhibitor News and Research

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New trial explores BAFF CAR T-cell therapy for relapsed myeloma

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Proteasomes: Expanding roles beyond cellular waste management

Proteasomes: Expanding roles beyond cellular waste management

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

Interactions between SIRT5 and SARS-CoV-2 Nsp14 protein

SARS-CoV-2 spike protein downregulates ACE2 expression

SARS-CoV-2 spike protein downregulates ACE2 expression

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Study shows the SARS-CoV-2 accessory protein ORF7a inhibits HLA-I surface expression levels in human cells

Research opens up new avenues for cancer treatment

Research opens up new avenues for cancer treatment

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Combination therapy shows potential for treating lung cancer

Combination therapy shows potential for treating lung cancer

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Exploring the effects of smoking tobacco on COVID-19 risk

Exploring the effects of smoking tobacco on COVID-19 risk

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Blocking the self-destruction process of enzymes can mitigate age-related diseases

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Daratumumab proves effective in patients with relapsed AL amyloidosis

Daratumumab proves effective in patients with relapsed AL amyloidosis

New combination therapy can lead to durable responses in patients with multiple myeloma

New combination therapy can lead to durable responses in patients with multiple myeloma

Study identifies risk factors for cardiotoxicity with relapsed multiple myeloma therapy

Study identifies risk factors for cardiotoxicity with relapsed multiple myeloma therapy

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

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