Protein Folding News and Research

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Researchers unlock specific mechanisms behind Aβ-induced cytoxicity in Alzheimer's disease

Alzheimer's disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. A person with Alzheimer's disease suffers loss of control over thought, memory and language abilities.

14 Feb 2017

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

NIH-funded scientists work with three ‘omes’ to understand human health

Have you ever collected coins, cards, toy trains, stuffed animals? Did you feel the need to complete the set? If so, then you may be a completist. A completist will go to great lengths to acquire a complete set of something.

17 Dec 2016

Research shows cellular component may play vital role in how lung cancer spreads

A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at The University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.

21 Nov 2016

Researchers need to know more about proinsulin misfolding to better understand diabetes

According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year.

17 Nov 2016

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

BGU researchers elucidate molecular mechanism that could lead to new therapies for ALS

Researchers from Ben-Gurion University of the Negev have published a new study that describes a novel molecular mechanism that could lead to the development of new therapies for Amyotrophic Lateral Sclerosis (ALS).

4 Oct 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

HIV, the virus that causes AIDS, has become one of the world’s most serious health and development challenges.

24 May 2016

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease, or bovine spongiform encephalopathy (BSE). A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk.

11 Apr 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin - NMR, EPR and Imaging 11 Feb 2016

Researchers trace origins of early abnormal brain overgrowth in ASD

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

14 Dec 2015

Scientists propose that Alzheimer's disease should be treated separately

Deciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of Jerusalem's Faculty of Medicine have proposed that the malady is actually a collection of diseases that probably should be treated with a variety of different approaches.

4 Nov 2015

Protein Folding News and Research

Researchers unlock specific mechanisms behind Aβ-induced cytoxicity in Alzheimer's disease

Researcher develops new method to accurately identify elusive molecules

NIH-funded scientists work with three ‘omes’ to understand human health

Research shows cellular component may play vital role in how lung cancer spreads

Researchers need to know more about proinsulin misfolding to better understand diabetes

Elucidating IDP behaviour on crowded membranes

BGU researchers elucidate molecular mechanism that could lead to new therapies for ALS

Rare genetic variations linked to severe porphyria

Mutant fruit flies provide insight into origins of Parkinson's disease

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Unlocking intrinsically disordered proteins: an interview with Peter Wright

Researchers trace origins of early abnormal brain overgrowth in ASD

Scientists propose that Alzheimer's disease should be treated separately

OSU discovery sheds new light on how proteins fold

New COMPASS platform points directly to protein's likely structure

Two researchers awarded NIH's New Innovator and Early Independence Awards

UT Southwestern researchers find a previously unknown genetic code

Redox equilibrium may help identify new diagnostic biomarkers for ageing, neurodegenerative processes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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