Pulmonary Fibrosis News and Research

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Researchers provide a clearer picture of healthy development of the lungs

Researchers have compiled the most comprehensive road map of the protein composition of human lungs, providing a clearer picture of the healthy development of this essential organ that made terrestrial life possible.

18 Nov 2021

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

18 Nov 2021

3D cell culturing platform allows study of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a deadly and rapidly progressing disease with no cure. The disease involves abnormal interactions between lung cells, including fibroblasts, and their surrounding environment.

16 Nov 2021

Updated mapping of the human genetic architecture of COVID-19

In the present study, researchers presented extensive meta-analysis and added ten new genome-wide significant loci.

15 Nov 2021

Therapeutic heparin for preventing COVID-19 deaths is four times higher than the prophylactic dose

The anti-coagulant heparin reduces the likelihood of death from COVID-19 by 78% when administered in therapeutic doses to patients with signs of respiratory failure on admission to hospital, according to a study reported on October 14 in the British Medical Journal.

30 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

Study identifies cells that may play a pivotal role in fibrotic scarring after lung transplant

A lung transplant can mean the difference between life and death for people with diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease (COPD) and even severe COVID-19.

8 Oct 2021

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

Researchers at Vanderbilt University Medical Center are leading a study designed to identify early drivers of pulmonary fibrosis in an at-risk patient population. Funding for the research, which could help predict early disease at the cellular level and possibly drive the development of novel therapies, is being provided by Three Lakes Foundation.

6 Oct 2021

A possible protective genetic polymorphism in COVID-19

A new study discusses the role of a mucin gene enhancer on the clinical phenotype of the COVID-19.

5 Oct 2021

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Now, in a new news study posted to the bioRxiv* preprint server, researchers have successfully induced similar chronicity associated with SARS-CoV-2 infection in MISTRG6-hACE2 humanized mice.

29 Sep 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Researchers identify 55 lingering effects of COVID-19

As COVID-19 hospitalizations once again soar in a fourth surge more than 18 months after the pandemic started, some patients continue to experience symptoms long after recovering from COVID, according to a Houston Methodist study recently published in Nature's Scientific Reports.

30 Aug 2021

Pulmonary Fibrosis News and Research

Researchers provide a clearer picture of healthy development of the lungs

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

3D cell culturing platform allows study of idiopathic pulmonary fibrosis

Updated mapping of the human genetic architecture of COVID-19

Therapeutic heparin for preventing COVID-19 deaths is four times higher than the prophylactic dose

Anti-rheumatic drug as a potential candidate for treating COVID-19

Study identifies cells that may play a pivotal role in fibrotic scarring after lung transplant

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

A possible protective genetic polymorphism in COVID-19

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Researchers identify 55 lingering effects of COVID-19

Study suggests a novel therapeutic target to reverse lung fibrosis

Single-cell RNA sequencing reveals cells that could protect from fatal lung disease

Researchers uncover genetic markers associated with COVID-19 infection risk and severity

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

Anti-viral treatment can stop the spread of lab modeled SARS-CoV-2 by 99.5%

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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