RNA News and Research

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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

'Junk' DNA suppresses breast cancer

Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.

2 Feb 2016

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

University of Massachusetts Medical School researchers have found a way to more efficiently delivery a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I that may also prove to be safer for use in humans.

2 Feb 2016

Study provides new insights into breast cancer metastasis

It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, a growing body of evidence suggests that these bad actors don't travel alone; instead they migrate through the body in cellular clusters, like gangs.

2 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Certain viral infections during pregnancy could cause behavioral changes in offspring

A study published in the journal Science found that activation in pregnant mice of a particular immune response, similar to what may occur with certain viral infections during pregnancy, alters the brain structure of the mouse offspring and causes behavioral changes, reminiscent of those observed in humans with autism spectrum disorder (ASD).

30 Jan 2016

Immune signaling molecule in infected mothers linked to behavioral abnormalities in offspring

In 2010, a large study in Denmark found that women who suffered an infection severe enough to require hospitalization while pregnant were much more likely to have a child with autism (even though the overall risk of delivering a child with autism remained low).

29 Jan 2016

Genetic mutations could help explain cause of cancer in pediatric patients

Combined whole exome tumor and blood sequencing in pediatric cancer patients revealed mutations that could help explain the cause of cancer or have the potential to impact clinical cancer care in 40 percent of patients in a study led by researchers from Baylor College of Medicine and Texas Children's Cancer Center.

29 Jan 2016

University of Leicester researchers publish structural details of protein linked to many types of cancer

A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer.

27 Jan 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

MDxHealth recognized with 2015 Global Frost & Sullivan Award for Technology Innovation

Based on its recent analysis of the prostate cancer diagnostics market, Frost & Sullivan recognizes MDxHealth with the 2015 Global Frost & Sullivan Award for Technology Innovation. To advance molecular diagnostic tests for urological cancers, MDxHealth supplemented its prostate cancer test, ConfirmMDx, with a urine-based "liquid-biopsy" test called SelectMDx.

21 Jan 2016

Paradigm, UnitedHealthcare sign contractual agreement for coverage of PCDx

Paradigm, a molecular information & Next Generation Sequencing corporation specializing in providing testing for cancer patients today announced that it has entered into a contractual agreement with UnitedHealthcare for coverage of PCDx.

21 Jan 2016

Rice scientists develop new tool to analyze thermal behaviors of DNA and RNA strands

Rice University scientists have developed a tool to speed the design of molecular diagnostics that depend on the specific recognition of pathogen DNA and RNA.

20 Jan 2016

Researchers identify protein that could protect against toxic degeneration of cells in ALS

J. Gavin Daigle, a PhD candidate at the LSU Health New Orleans School of Graduate Studies, is the first author of a paper whose findings reveal another piece of the Amyotrophic Lateral Sclerosis (ALS) puzzle.

19 Jan 2016

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites.

19 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

Small volumes of biological liquid waste easily aspirated

VACUSIP is an out-of-the-box solution. Simply connect the collection bottle to the built-in pump and choose the aspiration adapter matching your application. Operation is straight forward – switch the unit on and regulate the vacuum by applying pressure on the autoclavable hand adapter.

From INTEGRA Biosciences 14 Jan 2016

Simple paper test could confirm presence of illnesses even before patients feel symptoms

A multi-disciplinary team of researchers has developed a new diagnostic test that can change the medical landscape by making it possible for patients to quickly determine if they are infected with an illness, using a simple paper test sensitive enough to detect markers of various illnesses using minute amounts of blood, sweat, or other biological material.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

Genomics portfolio expanded by Illumina

Illumina, Inc., the global leader in sequencing and array-based technologies, today announced the newest addition to its industry-leading next-generation sequencing (NGS) portfolio with the launch of the MiniSeq Sequencing System.

From Illumina, Inc. 12 Jan 2016

LabCorp to offer Interpace's new ThyraMir microRNA classifier test

Interpace Diagnostics announced today that Laboratory Corporation of America Holdings, the world's leading health care diagnostics company, will begin offering Interpace's new ThyraMir microRNA classifier test.

12 Jan 2016

RNA News and Research

Further Reading

'Junk' DNA suppresses breast cancer

New way to more efficiently deliver CRISPR/Cas9 therapeutic to mice with Tyrosinemia type I

Study provides new insights into breast cancer metastasis

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Certain viral infections during pregnancy could cause behavioral changes in offspring

Immune signaling molecule in infected mothers linked to behavioral abnormalities in offspring

Genetic mutations could help explain cause of cancer in pediatric patients

University of Leicester researchers publish structural details of protein linked to many types of cancer

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

MDxHealth recognized with 2015 Global Frost & Sullivan Award for Technology Innovation

Paradigm, UnitedHealthcare sign contractual agreement for coverage of PCDx

Rice scientists develop new tool to analyze thermal behaviors of DNA and RNA strands

Researchers identify protein that could protect against toxic degeneration of cells in ALS

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Small volumes of biological liquid waste easily aspirated

Simple paper test could confirm presence of illnesses even before patients feel symptoms

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

Genomics portfolio expanded by Illumina

LabCorp to offer Interpace's new ThyraMir microRNA classifier test

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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