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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Next-generation sequencing may help discover genetic changes that might lead to cancer

A pilot study led by the Translational Genomics Research Institute and the Virginia G. Piper Cancer Center at Scottsdale Healthcare shows that, even for patients with advanced and rapidly transforming cancer, researchers can find potential therapeutic targets using the latest advances in genomic sequencing.

31 Oct 2013

New insights into human cytomegalovirus may lead to development of therapeutic interventions

New insights into how human cytomegalovirus, the leading cause of birth defects associated with infection spreads from pregnant mother to fetus and from organ to organ in newborns provides translational researchers an exciting new avenue for investigation that may lead to the development of therapeutic interventions.

31 Oct 2013

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome.

25 Oct 2013

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

University of Massachusetts Medical School Assistant Professor of Biochemistry and Molecular Pharmacology Gang Han, PhD, has received a $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Mental Health to develop light activated nanoparticles that can be used to image live brain tissue.

25 Oct 2013

"One-two punch" disables tumors' defenses

An aggressive form of breast cancer known as "triple negative" is very difficult to treat: Chemotherapy can shrink such tumors for a while, but in many patients they grow back and gain resistance to the original drugs.

25 Oct 2013

Promising technique for treating eye disease proves effective in preclinical studies

A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California.

23 Oct 2013

Illumina announces launch of TruGenome Undiagnosed Disease Test

Illumina, Inc. today announced the launch of its TruGenome Undiagnosed Disease Test provided by the CLIA-certified, CAP-accredited Illumina Clinical Services Laboratory.

From Illumina, Inc. 22 Oct 2013

New collaborative project aims to discover genes underlying rare genetic diseases

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21 Oct 2013

Inovio Pharmaceuticals begins phase I clinical trial for hepatitis C vaccine

Inovio Pharmaceuticals, Inc. announced today that the safety, tolerability and immunogenicity of its therapeutic vaccine for hepatitis C (INO-8000/VGX-6150) will be studied in a phase I clinical trial in chronically HCV infected patients.

21 Oct 2013

Genetic mutation found to restore translational balance in mice

In a biological quirk that promises to provide researchers with a new approach for studying and potentially treating Fragile X syndrome, scientists at the University of Massachusetts Medical School (UMMS) have shown that knocking out a gene important for messenger RNA (mRNA) translation in neurons restores memory deficits and reduces behavioral symptoms in a mouse model of a prevalent human neurological disease.

21 Oct 2013

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Veracyte, Inc., a molecular diagnostics company pioneering the field of molecular cytology, today announced preliminary study results suggesting the potential for an RNA-based gene expression test to accurately detect the BRAF V600E gene mutation in thyroid nodule fine needle aspiration (FNA) samples.

19 Oct 2013

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents.

19 Oct 2013

Study shows how two miRNAs regulate FOXP2 gene implicated in speech, language impairments

A study led by Xiaoching Li, PhD, at the LSU Health Sciences Center New Orleans Neuroscience Center of Excellence, has shown for the first time how two tiny molecules regulate a gene implicated in speech and language impairments as well as autism disorders, and that social context of vocal behavior governs their function.

18 Oct 2013

Merck to present pharmacokinetic data on once-daily ISENTRESS at EACS

Merck, known as MSD outside the United States and Canada, is presenting pharmacokinetic data this week on investigational formulations of a once daily dose of ISENTRESS at the 14th European AIDS Conference, sponsored by the European AIDS Clinical Society.

17 Oct 2013

King's College researchers identify new biomarker that detects sepsis in blood

Researchers at King's College London have identified a biomarker - a biological 'fingerprint' - for sepsis in the blood, and showed it could be possible to diagnose the condition within two hours by screening for this biomarker at a patient's bedside.

17 Oct 2013

Imaxio Sells Genomics Division To Hybrigenics

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16 Oct 2013

Trovagene launches pharmaceutical alliance to monitor lung cancer patients' EGFR mutational status

Trovagene, Inc., a developer of cell-free molecular diagnostics, today announced that it will collaborate with a pharmaceutical company to evaluate Trovagene's proprietary, urine-based, cell-free DNA technology for the detection of certain epidermal growth factor receptor mutations associated with lung cancer.

16 Oct 2013

Seven promising scientists named 2013 NYSCF - Robertson Investigators

The New York Stem Cell Foundation today named seven of the most promising scientists as its 2013 NYSCF - Robertson Investigators.

16 Oct 2013

Janssen seeks European marketing approval for combination of once-daily darunavir with cobicistat

Janssen-Cilag International NV, today announced it has submitted a Marketing Authorisation Application to the European Medicines Agency seeking approval for a once-daily single tablet fixed-dose antiretroviral combination product containing darunavir, a protease inhibitor developed by Janssen, with cobicistat, a pharmacokinetic enhancer or boosting agent, developed by Gilead Sciences, Inc. for use in combination with other human immunodeficiency virus medicines.

15 Oct 2013

Study provides novel link between cellular aging and diffuse large B-cell lymphoma

Scientists at the University of Massachusetts Medical School have shown that diffuse large B-cell lymphoma (DLBCL) may be susceptible to treatment by re-activating the normal aging program in tumor cells so they can no longer divide.

15 Oct 2013

RNA News and Research

Further Reading

Next-generation sequencing may help discover genetic changes that might lead to cancer

New insights into human cytomegalovirus may lead to development of therapeutic interventions

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

"One-two punch" disables tumors' defenses

Promising technique for treating eye disease proves effective in preclinical studies

Illumina announces launch of TruGenome Undiagnosed Disease Test

New collaborative project aims to discover genes underlying rare genetic diseases

Inovio Pharmaceuticals begins phase I clinical trial for hepatitis C vaccine

Genetic mutation found to restore translational balance in mice

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Study shows how two miRNAs regulate FOXP2 gene implicated in speech, language impairments

Merck to present pharmacokinetic data on once-daily ISENTRESS at EACS

King's College researchers identify new biomarker that detects sepsis in blood

Imaxio Sells Genomics Division To Hybrigenics

Trovagene launches pharmaceutical alliance to monitor lung cancer patients' EGFR mutational status

Seven promising scientists named 2013 NYSCF - Robertson Investigators

Janssen seeks European marketing approval for combination of once-daily darunavir with cobicistat

Study provides novel link between cellular aging and diffuse large B-cell lymphoma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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