Remdesivir News and Research

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COVID-19 clinical trials show positive early results, says GlobalData

With the number of COVID-19 cases and deaths increasing with each passing day, the need for a therapeutic or a vaccine for the pandemic intensifies.

18 May 2020

COVID-19’s adverse impact on the cardiovascular system

COVID-19 can cause serious cardiovascular complications including heart failure, heart attacks and blood clots that can lead to strokes, emergency medicine doctors report in a new scientific paper.

15 May 2020

Chasing the elusive dream of a COVID cure

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off — and might never arrive.

15 May 2020

Study shows 19 out of 25 COVID-19 patients improved with convalescent plasma treatment

The country's first convalescent plasma transfusion trial results have been published and show 19 out of 25 patients improved with the treatment, and 11 were discharged from the hospital.

13 May 2020

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

UCI Health will initiate a clinical study of a drug to treat critically ill COVID-19 patients who face a high mortality rate because of acute inflammation that fills their lungs with fluid, a grave condition that even mechanical ventilation cannot improve.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Perspective: Existing drugs could be repurposed for COVID-19 patients

Given the rapid spread of COVID-19 and its relatively high mortality, filling the gap for coronavirus-specific drugs is urgent.

9 May 2020

NIH clinical trial evaluates antiviral plus anti-inflammatory drug for COVID-19

A randomized, controlled clinical trial evaluating the safety and efficacy of a treatment regimen of the investigational antiviral remdesivir plus the anti-inflammatory drug baricitinib for coronavirus disease 2019 (COVID-19) has begun.

8 May 2020

Repurposing existing drugs is a more rapid alternative than developing COVID-19 vaccine

Repurposing existing medicines focused on known drug targets is likely to offer a more rapid hope of tackling COVID-19 than developing and manufacturing a vaccine, argue an international team of scientists in the British Journal of Pharmacology today.

8 May 2020

Most COVID-19 patients lose sense of smell by the third day, shows study

A University of Cincinnati researcher says a study of COVID-19 patients shows loss of the sense of smell is most likely to occur by the third day of infection with the novel virus. Most of these patients are also experiencing a loss of the sense of taste.

8 May 2020

Excluding children from COVID-19 clinical trials may limit their treatment options

A new viewpoint article from Harvard Medical School, published in the journal JAMA Pediatrics, discusses the hesitancy to include children in coronavirus disease 2019 (COVID-19) clinical trials, potentially diminishing their therapeutic options in the long run.

7 May 2020

MU researcher finds four antiviral drugs effective in inhibiting novel coronavirus

Now, a researcher at the University of Missouri has found that four antiviral drugs, including remdesivir, a drug originally developed to treat Ebola, are effective in inhibiting the replication of the coronavirus causing COVID-19.

4 May 2020

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

A team of Chinese scientists have reported the high-resolution cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2, the infective virus of COVID-19.

3 May 2020

KHN’s ‘What the Health?’: SCOTUS decides an ACA case. No, not that case.

The Supreme Court this week rejected the efforts of a Republican-controlled Congress in 2014 to cut off funding to insurance companies under a provision of the Affordable Care Act.

30 Apr 2020

As coronavirus strikes, crucial data in electronic health records hard to harvest

When President Donald Trump started touting hydroxychloroquine as "one of the biggest game changers” for treating COVID-19, researchers hoped electronic health records could quickly tell them if he was on the right track.

30 Apr 2020

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Temple University Hospital is now participating in a variety of clinical trials that are testing investigational treatment options for patients diagnosed with the novel coronavirus, or COVID-19.

30 Apr 2020

Remdesivir shows powerful activity against SARS-CoV-2 in Vitro

Remdesivir is an antiviral first developed by Gilead in 2014 as a treatment for Ebola and Marburg viruses. However, scientists explored its possibilities as a broad-spectrum drug when it proved effective against SARS-CoV and MERS-CoV, coronaviruses which were responsible for earlier outbreaks.

30 Apr 2020

Remdesivir News and Research

COVID-19 clinical trials show positive early results, says GlobalData

COVID-19’s adverse impact on the cardiovascular system

Chasing the elusive dream of a COVID cure

Study shows 19 out of 25 COVID-19 patients improved with convalescent plasma treatment

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

Study shows why older individuals are vulnerable to COVID-19

Perspective: Existing drugs could be repurposed for COVID-19 patients

NIH clinical trial evaluates antiviral plus anti-inflammatory drug for COVID-19

Repurposing existing drugs is a more rapid alternative than developing COVID-19 vaccine

Most COVID-19 patients lose sense of smell by the third day, shows study

Excluding children from COVID-19 clinical trials may limit their treatment options

MU researcher finds four antiviral drugs effective in inhibiting novel coronavirus

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

KHN’s ‘What the Health?’: SCOTUS decides an ACA case. No, not that case.

As coronavirus strikes, crucial data in electronic health records hard to harvest

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Remdesivir shows powerful activity against SARS-CoV-2 in Vitro

GlobalData offers view on Gilead’s suspension of Covid-19 trials in China

UAB to join international effort to test drugs for COVID-19

Research looks at best ways to tackle coronavirus crisis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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