Retinoic Acid News and Research

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Retinoic Acid is a nutrient that that body needs in small amounts to function and stay healthy. All-trans retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo. A form of all-trans retinoic acid made in the laboratory is put on the skin to treat conditions such as acne and is taken by mouth to treat acute promyelocytic leukemia (a fast-growing cancer in which there are too many immature blood-forming cells in the blood and bone marrow). All-trans retinoic acid is being studied in the prevention and treatment of other types of cancer. Also called ATRA, retinoic acid, tretinoin, and vitamin A acid.

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

Researchers evaluated the anti-metastatic and anti-proliferative properties of all-trans retinoic acid (ATRA) and dandelion extract in breast cancer cells.

14 Sep 2023

Can yoga alleviate rheumatoid arthritis severity?

A recent Scientific Reports study investigated the effect of yoga on rheumatoid arthritis (RA) severity.

13 Sep 2023

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

The role of self-extracellular nucleic acids in neuroinflammation

Researchers explore the role of self-extracellular nucleic acids in diseases like stroke, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease.

14 Aug 2023

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants.

11 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

A group of authors summarized adjuvant mechanisms, characteristics, and applications, seeking to overcome current vaccine limitations.

21 Jul 2023

Case report and review of a novel chromosomal abnormality in AML patient

A new research paper was published in Genes & Cancer on June 28, 2023, entitled, "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature."

7 Jul 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Researchers develop a method for making “mini-heart” using pluripotent stem cells

A team at the Technical University of Munich has induced stem cells to emulate the development of the human heart.

5 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

Scientists identify a distinct role of retinoic acid during immune response of the gut

A team of scientists from the Renaissance School of Medicine at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

28 Mar 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

CU study proves effectiveness of new multidrug treatment for patients with stage IV melanoma

A new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year clinical trial at the University of Colorado Cancer Center.

16 Dec 2022

Simplified treatment regimen results in dramatic decrease in early deaths from acute promyelocytic leukemia

The use of a simplified treatment regimen by oncologists, along with management recommendations and 24/7 support provided by a limited and dedicated group of academic disease experts, resulted in a dramatic decrease in early deaths from acute promyelocytic leukemia (APL).

12 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022