Retrovirus News and Research

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Study reveals how ASV and HIV-1 share similar structural features that drive membrane targeting, assembly

A key step in retroviral growth inside a cell, as described by Jamil Saad, Ph.D., and colleagues, is portrayed on the cover of The Journal of Biological Chemistry.

18 Dec 2018

Survey finds high prevalence of HTLV-1 infection among teens and adults in Gabon

A study published in PLOS Neglected Tropical Diseases, by Mirdad Kazanji, of the Centre International de Recherches Medicales de Franceville in Gabon, and the Institut Pasteur de la Guyane in French Guiana, suggests that 30 years after the first epidemiological survey of the seroprevalence of Human T-cell lymphotropic virus type 1 (HTLV-1) infections in Gabon, the country remains highly endemic, with a seroprevalence of 7.3%.

19 Oct 2018

Researchers provide new knowledge about retrovirus-host coevolution

Retroviruses have colonized vertebrate hosts for millions of years by inserting their genes into host genomes, enabling their inheritance through generations as endogenous retroviruses.

8 Oct 2018

Koala virus could provide clues to accumulated 'junk' DNA in the human genome

A koala virus could help researchers explain millions of years of accumulated ‘junk’ DNA in the human genome.

10 Aug 2018

Scientists elucidate 3D structure of protein involved in cancer

The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses.

6 Jun 2018

'Molecular scissors' could play pivotal role in fighting diseases including HIV infection

One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works to influence the immune system, new research suggests.

3 Apr 2018

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

The social stigma surrounding HIV is still strong in many parts of the world. Children living with HIV in Ethiopia are at high risk of receiving inadequate treatment - or no treatment at all - on account of deeply rooted prejudice.

14 Dec 2017

Scientists receive critical funding to study treatments for three deadly cancers

Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of the deadliest forms of cancer: glioblastoma (brain cancer), sarcoma (bone cancer) and ovarian cancer.

17 Oct 2017

Cow immunization may lead to new human vaccines and treatments for HIV, study finds

Antibodies against the Human Immunodeficiency Virus (HIV) have been obtained for the first time by injecting cows with an HIV antigen. This achievement offers promise for the development of anti-HIV treatments or vaccines.

21 Jul 2017

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Researchers from Memorial Sloan Kettering Cancer Center have harnessed the power of CRISPR/Cas9 to create more-potent chimeric antigen receptor (CAR) T cells that enhance tumor rejection in mice.

23 Feb 2017

UCL researchers discover how HIV infects macrophages despite presence of protective protein

A team led by UCL researchers has identified how HIV is able to infect macrophages, a type of white blood cell integral to the immune system, despite the presence of a protective protein.

27 Jan 2017

Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects.

16 Dec 2016

Researchers create first mouse model for common form of infant leukemia

After nearly two decades of unsuccessful attempts, researchers from the University of Chicago Medicine and the Cincinnati Children's Hospital Medical Center have created the first mouse model for the most common form of infant leukemia.

15 Nov 2016

New technology uses USB stick to monitor HIV in bloodstream

The device, created by scientists at Imperial College London and DNA Electronics, uses a drop of blood to detect HIV, and then creates an electrical signal that can be read by a computer, laptop or handheld device.

10 Nov 2016

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

A study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV.

9 Nov 2016

WSU researcher finds a way to reduce development of cancer cells

A Washington State University researcher has developed a way to reduce the development of cancer cells that are an infrequent but dangerous byproduct of gene therapy.

5 Nov 2016

Coordinated treatment for both illnesses could save lives of people with HIV and TB

Tuberculosis (TB) is a leading killer of people with HIV, and providing therapy for both illnesses simultaneously saves lives - according to new guidelines on the treatment of drug-susceptible TB developed jointly by the American Thoracic Society, Centers for Disease Control and Prevention and Infectious Diseases Society of America.

11 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

First confirmed case of Alzheimer’s disease in HIV-positive patient to be presented at AAIC 2016

The first case of Alzheimer's disease diagnosed in an HIV-positive individual will be presented in a poster session at the Alzheimer's Association International Conference 2016 in Toronto July 27.

26 Jul 2016

New treatment may destroy HIV's last refuge

UK scientists may have found a way to destroy HIV's last refuge. A study by Oxford University has confirmed that a treatment developed by a British company can remove the virus in its chosen hiding place, in laboratory conditions, offering hope of a viable treatment.

15 Jul 2016