Ribonucleic Acid News and Research

RSS

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Researchers explore the thermodynamic properties of the SARS-CoV-2 Omicron subvariant BA.2.75 to understand its increased transmissibility.

27 Oct 2022

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Researchers assessed the impact of SARS-CoV-2 vaccination on the occurrence and severity of symptoms in SARS-CoV-2 Omicron-infected hospitalized patients.

27 Oct 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

Omicron BA.4/BA.5 bivalent mRNA vaccine booster elicits similar neutralizing antibody responses to monovalent vaccine

Researchers analyzed the antibody response induced by the new bivalent mRNA SARS-CoV-2 vaccines in individuals who have been fully vaccinated with monovalent vaccines and those who have had breakthrough infection with the SARS-CoV-2 Omicron BA.4/BA.5 variants.

26 Oct 2022

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers analyzed the phenotypes of the SARS-CoV-2 variants of concern (VOCs), the molecular responses to infections from these VOCs, and the evolving virus-host interactions using a comparative genomic and proteomic approach.

26 Oct 2022

COVID-19 and the gut

Researchers summarize current knowledge about underlying mechanisms and potential therapeutic approaches for the effects of COVID-19 on the gut.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

The swine acute diarrhea syndrome coronavirus promotes autophagy to maintain its replication inside host cells.

26 Oct 2022

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Researchers explored genomic rearrangements in monkeypox virus genomes and investigated whether such rearrangements represented viral adaption to humans (host).

25 Oct 2022

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

In a new study, researchers investigated whether low-complexity regions (LCRs) were more accountable for the current 2022 IIb clade monkeypox (MPX) virus (MPXV) outbreak rather than single-nucleotide polymorphisms (SNPs).

24 Oct 2022

Investigating the evidence of synthetic origins of SARS-CoV-2

Researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated naturally from an animal-to-human spillover or synthetically during coronavirus research experiments.

24 Oct 2022

Risk of viral spillover found to increase with a warming climate in High Arctic lake sediments

In a new study, researchers performed a combined metagenomic and cophylogenetic modeling analysis to evaluate the impact of climate change on viral spillover risks in the context of a changing High Arctic environment.

24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

Researchers investigated the efficacy of monovalent mRNA COVID-19 vaccines in immunocompromised adults during the Omicron dominance period starting December 2021.

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

In a recent study published in the New England Journal of Medicine, researchers presented the findings of the ongoing KidCOVE trial in the United States (US).

23 Oct 2022

Ribonucleic Acid News and Research

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Omicron BA.4/BA.5 bivalent mRNA vaccine booster elicits similar neutralizing antibody responses to monovalent vaccine

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

COVID-19 and the gut

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

Genomic rearrangements in monkeypox virus could be a sign of adaption to the human host

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

Investigating the evidence of synthetic origins of SARS-CoV-2

Risk of viral spillover found to increase with a warming climate in High Arctic lake sediments

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

A novel approach for viral genomic surveillance

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News