Selective Serotonin Reuptake Inhibitor (SSRI) News and Research

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Selective Serotonin Reuptake Inhibitor (SSRI) is a type of drug that is used to treat depression. SSRIs slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves. Also called selective serotonin reuptake inhibitor.

Insomnia patients often denied sleep treatment when they have mental health problems

Patients with insomnia who are diagnosed with accompanying mental health ailments often are not prescribed medication that will help them sleep - which could then make related anxiety or depression worse, new research suggests.

4 Feb 2008

Antidepressants might be worthless for treating low back pain

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

30 Jan 2008

FDA warnings appeared to effectively increase perception of risks involved with antidepressant treatment

U.S. Food and Drug Administration warnings regarding the risk of suicidal thoughts and behaviors in children and adolescents taking antidepressants appear to have had modest and targeted effects on the intended populations, according to a report in the January issue of Archives of General Psychiatry.

8 Jan 2008

Synthetic form of THC is an effective anti-depressant at low doses

A new neurobiological study has found that a synthetic form of THC, the active ingredient in cannabis, is an effective anti-depressant at low doses.

24 Oct 2007

Little evidence to support therapies for post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is a severe and ongoing emotional reaction to an extreme psychological trauma; it affects significant numbers of people, in particular military personnel and veterans, who have seen active duty in war zones.

22 Oct 2007

Review of PTSD treatments

Many people, including significant proportions of active duty military personnel and veterans, suffer from post-traumatic stress disorder (PTSD), often in conjunction with other injuries or illnesses.

19 Oct 2007

Depression among patients with coronary artery disease

Depression has long had a popular link to cardiovascular disease and death. However, only during the last 15 years scientific evidence supporting this common wisdom has been available (Glassman et al., 2007a).

16 Oct 2007

SSRIs may double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues.

9 Oct 2007

Taking antidepressants with painkillers dangerous

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

9 Oct 2007

Variations in two genes linked to suicidal thinking

Specific variations in two genes are linked to suicidal thinking that sometimes occurs in people taking the most commonly prescribed class of antidepressants, according to a large study led by scientists at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

27 Sep 2007

Antidepressant citalopram shows promise in treating symptoms of dementia

Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia.

11 Sep 2007

Dapoxetine for the treatment of premature ejaculation.

Premature ejaculation (PE) is defined as “persistent or recurrent onset of orgasm and ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the person wishes it.”

29 Aug 2007

UIC receives $9.6 million grant for autism research

The University of Illinois at Chicago has been awarded a $9.6 million, five-year grant from the National Institutes of Health to establish an Autism Center of Excellence.

7 Aug 2007

Study challenges NICE guidelines that recommend SSRIs be prescribed only in conjunction with psychological therapies

Should adolescents with depression be prescribed antidepressants, and if so, should they be given only with a psychological therapy, as advocated by the National Institute for Health and Clinical Excellence (NICE)"

20 Jul 2007

Antidepressants lower the risk of suicide attempt in adults with depression

All age groups of depressed patients who received selective serotonin reuptake inhibitors -- the most commonly prescribed antidepressant medication -- showed a significantly lower risk of suicide attempt when compared to those who did not receive antidepressant treatment.

9 Jul 2007

Antidepressant warnings linked to decreased prescription rates among children

Regulatory warnings regarding the risk of suicidal thoughts and behaviors appear to be associated with reductions in the number of antidepressant medication prescriptions among children and adolescents covered by Tennessee's expanded Medicaid program, according to a report in the July issue of Archives of Pediatrics & Adolescent Medicine.

4 Jul 2007