Severe Acute Respiratory News and Research

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Filter using whey protein nanofibrils and iron oxyhydroxides nanoparticles catches viruses, including SARS-CoV-2

A recent Swiss study posted to the bioRxiv* preprint server demonstrated that aerosol filters centered on granular protein nanofibrils and iron (Fe) oxyhydroxides nanoparticles could trap virus-containing aerosols.

4 Jul 2022

How does obesity affect the immune system?

A new study summarizes new findings on the immunoregulatory effects of excessive fat stores or malnutrition through Th2 cells.

4 Jul 2022

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Researchers evaluated the presence of RNA of SARS-CoV-2 in lung tissue of deceased patients.

4 Jul 2022

Impact of SARS-CoV-2 infection on menstrual cycle

Researchers systematically reviewed the impact of COVID-19 on the menstrual cycle.

4 Jul 2022

Exploring flavonols in the inhibition of SARS-CoV-2 replication

Researchers assessed the efficiency of flavonols in SARS-CoV-2 inhibition.

4 Jul 2022

The role of vitamin D in H1N1 influenza and SARS-CoV-2 infection

A new study focused on determining Vitamin D's role in SARS-CoV-2 and H1N1 influenza. In this study, researchers determined the effect of vitamin D supplements on the lung anti-viral response in animal models.

4 Jul 2022

Age-specific precision shielding in the pre-vaccination period of the COVID-19 pandemic

A new study has focussed on addressing whether age-specific precision shielding was achieved in the pre-vaccination period.

4 Jul 2022

Brain immune response to SARS-CoV-2 infection

In a recently published article in the journal Current Opinion in Neurobiology, scientists at Washington University School of Medicine, St. Louis have described how immunological alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may impact brain activities and induce acute and post-acute neurological symptoms in coronavirus disease 2019 (COVID-19) patients.

3 Jul 2022

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Despite significant and stunning advances in vaccine technology, the COVID-19 global pandemic is not over. A key challenge in limiting the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is identifying infected individuals.

1 Jul 2022

Remdesivir resistance in renal transplant patients with long COVID-19

A new study has reported two renal transplant cases, in which individuals, after being exposed to remdesivir, developed a resistance to the drug.

1 Jul 2022

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Researchers explored the molecular basis for increased immunity against heterologous SARS-CoV-2 strains after repeated antigen exposures.

1 Jul 2022

The antiviral effects of thiol drugs in COVID-19

A recent study investigated the effects of thiol drugs on SARS-CoV-2.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

Researchers assessed the impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

How sleep distress associated with melatonin imbalance may play a role in the presence, intensity, and severity of anosmia

In a recent study published in the International Journal of Developmental Neuroscience, researchers assessed the role of melatonin in COVID-19-associated anosmia.

1 Jul 2022

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

In a recent article posted to the bioRxiv* preprint server, researchers at Rutgers, the State University of New Jersey, the University of South Florida, and the Catholic University of America demonstrated that the natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) mutations result in nirmatrelvir resistance.

30 Jun 2022

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.

30 Jun 2022

Evidence review on "long-distance" airborne transmission of SARS-CoV-2

In a recent study published in the BMJ, researchers investigated the factors that might influence the long-distance (more than two meters) airborne transmission of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in real-world indoor settings, e.g., workplaces and residential apartments.

30 Jun 2022

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

In a recent study published in the New England Journal of Medicine, researchers evaluated the effectiveness of the BNT162b2 vaccine against the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron in five to 11-year-old children.

30 Jun 2022

Severe Acute Respiratory News and Research

Filter using whey protein nanofibrils and iron oxyhydroxides nanoparticles catches viruses, including SARS-CoV-2

How does obesity affect the immune system?

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Impact of SARS-CoV-2 infection on menstrual cycle

Exploring flavonols in the inhibition of SARS-CoV-2 replication

The role of vitamin D in H1N1 influenza and SARS-CoV-2 infection

Age-specific precision shielding in the pre-vaccination period of the COVID-19 pandemic

Brain immune response to SARS-CoV-2 infection

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Remdesivir resistance in renal transplant patients with long COVID-19

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

The antiviral effects of thiol drugs in COVID-19

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

How sleep distress associated with melatonin imbalance may play a role in the presence, intensity, and severity of anosmia

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

Evidence review on "long-distance" airborne transmission of SARS-CoV-2

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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