Severe Acute Respiratory News and Research

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Environmental microbiome's impact on COVID-19 mortality

A new study published on the medRxiv* preprint server was based on the hypothesis that the environmental mycobiome (fungi) is a likely important factor in determining area-level variation in COVID-19 mortality.

19 Dec 2021

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Study shows risk of long-term impact of COVID-19 on patients with cardiovascular diseases and diabetes mellitus

British researchers analyze the net effect of COVID-19 on cardiometabolic outcomes over one month, three months, and twelve months.

19 Dec 2021

CRISPR-based microfluidic platform detects respiratory viruses and SARS-CoV-2 variants

Researchers in the US have developed a novel multiplexed diagnostic platform based on CRISPR-based approaches and microfluidics - enabling robust and simultaneous surveillance of multiple viruses and viral variants. Currently, the paper is available on the medRxiv* preprint server pending peer review.

19 Dec 2021

Production of functional SARS-CoV-2 spike protein in single-cell green alga

A new study uses a novel algal platform for the generation of the SARS-CoV-2 spike protein.

19 Dec 2021

Study says COVID mRNA-based vaccines best for booster vaccination

A new study looks at the adaptive immune response to COVID-19 vaccines, wherein the authors compare heterologous to homologous immunization.

19 Dec 2021

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

A new study describes the results of using an extract of the medicinal plant Echinacea purpurea to treat non-severe cases of COVID-19.

19 Dec 2021

Study suggests 2/3 of Dutch children < 12 years have been infected with SARS-CoV-2

Researchers conduct intensive and longitudinal monitoring of households with children of different ages for the presence of SARS-CoV-2.

19 Dec 2021

Efficacy of NVX-CoV2373 in the US and Mexican adult population

A new study has described the results of PREVENT-19, a phase 3 trial of NVX-CoV2373 that included all adults in the United States and Mexico.

17 Dec 2021

Investigating potential cross-protection against SARS-CoV-2 after previous exposure to bovine coronavirus

Researchers have conducted an investigation to probe the similarity of viral epitopes between bovine coronavirus (BCoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Dec 2021

Simulating transmission dynamics of SARS-CoV-2 Omicron variant

Researchers simulated the emergence of Omicron, a novel SARS-CoV-2 VOC, in a general European setting using an individual-based transmission model.

17 Dec 2021

Predicting local surges of COVID-19 hospitalizations in 2022

Researchers have identified simple and easy-to-communicate decision rules to provide early warnings - when a pre-specified threshold of hospital capacity will likely be exceeded within a four or eight week period.

17 Dec 2021

Modeling the potential interaction between COVID-19 outbreaks in susceptible and vaccinated sub-populations

Researchers demonstrated that the combination of infection of remaining susceptible individuals and breakthrough infections of vaccinated individuals promotes infection by invading variants.

17 Dec 2021

Vaccine effectiveness against COVID-19 caused by Omicron and Delta SARS-CoV-2 variants in England

Researchers performed a test-negative case-control study to determine the effectiveness of BNT162b2 and ChAdOx1 COVID-19 vaccines against the Omicron and Delta variants of SARS-CoV-2.

17 Dec 2021

Effectiveness of COVID-19 vaccines among older male veterans

A new research letter assessed the effectiveness of the mRNA1273 and BNT162b2 vaccines among fully vaccinated male veterans who were 65 years of age or above from July to September 2021.

17 Dec 2021

Primary responses to SARS-CoV-2 in COVID-19 naïve vaccinees

Researchers evaluated primary responses in SARS-CoV-2-naïve vaccinees, as well as secondary responses in the SARS-CoV-2-infected vaccines, and observed a clear set of differences in their clinical symptoms, antibody levels, and cellular and mucosal immune responses.

17 Dec 2021

Severe Acute Respiratory News and Research

Environmental microbiome's impact on COVID-19 mortality

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Study shows risk of long-term impact of COVID-19 on patients with cardiovascular diseases and diabetes mellitus

CRISPR-based microfluidic platform detects respiratory viruses and SARS-CoV-2 variants

Production of functional SARS-CoV-2 spike protein in single-cell green alga

Study says COVID mRNA-based vaccines best for booster vaccination

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

Study suggests 2/3 of Dutch children < 12 years have been infected with SARS-CoV-2

Efficacy of NVX-CoV2373 in the US and Mexican adult population

Investigating potential cross-protection against SARS-CoV-2 after previous exposure to bovine coronavirus

Simulating transmission dynamics of SARS-CoV-2 Omicron variant

Predicting local surges of COVID-19 hospitalizations in 2022

Modeling the potential interaction between COVID-19 outbreaks in susceptible and vaccinated sub-populations

Vaccine effectiveness against COVID-19 caused by Omicron and Delta SARS-CoV-2 variants in England

Effectiveness of COVID-19 vaccines among older male veterans

Primary responses to SARS-CoV-2 in COVID-19 naïve vaccinees

Identifying protein targets in SARS-CoV-2 via machine learning

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Investigating SARS-CoV-2 genomics-informed outbreaks using new bioinformatics tools

Prediction of waning COVID-19 vaccine efficacy against Omicron variant

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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