Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

A study published in the journal Clinical Nutrition provides new knowledge on the health effects of a diet rich in nuts.

7 Oct 2021

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

Researchers discover major metabolite involved in regulating intestinal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

19 Jul 2021

Short chain fatty acids have potential therapeutic applications against COVID-19, study suggests

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly transmissible, with nasal passages being the target of original infection.

15 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

Comprehensive reference on the science, technology, and applications of postbiotics

Postbiotics: Science, Technology, and Applications explains essential and practical knowledge about postbiotics. Chapters cover the definition and classification of postbiotics, principal methods for preparing them, information about the main post biotic constituents and their biological activities and their clinical health benefits.

25 Jun 2021

Imbalance in gut microbiota could play a key role in progression of inflammatory skin disorder

Findings presented at today’s EADV 2021 Spring Symposium suggest that an imbalance in gut microbiota (dysbiosis), could play a significant role in the progression of inflammatory skin disease, Hidradenitis Suppurativa (HS).

7 May 2021

Overgrowth of gut yeast in newborns associated with increased risk of asthma

An overgrowth of yeast in the gut within the first few months of life may cause changes to the immune system that increase the risk of asthma later on, shows a study published today in eLife.

20 Apr 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

High-fiber diet can significantly alter the gut microbiome and nutrient intake

A short-term intervention in daily fiber consumption can significantly alter the gut microbiome and nutrient intake, according to a study led by University of California, Irvine researchers. The research was recently published by the American Society for Microbiology.

26 Mar 2021

Ancestral components of human gut microbiota are fundamental to health

Neanderthals' gut microbiota already included some beneficial micro-organisms that are also found in our own intestine.

5 Feb 2021

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

The distinctive gut microbiome profile of a person with liver cancer linked to non-alcoholic fatty liver disease (NAFLD) could be the key to predicting someone's risk of developing the cancer, say researchers from the UNSW Microbiome Research Centre.

4 Feb 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

Study confirms link between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

Probiotics may help manage obesity in younger population

Probiotics may help children and adolescents with obesity lose weight when taken alongside a calorie-controlled diet, according to a study being presented at e-ECE 2020.

7 Sep 2020

Blood cell damage in COVID-19 may compromise oxygen transport

Researchers in the U.S. have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may alter key protein structures on red blood cells and compromise the transport and delivery of oxygen in patients with coronavirus disease 2019 (COVID-19).

1 Jul 2020

Common food additive alters gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

25 Jun 2020

Study finds overabundance of opportunistic pathogens in the guts of persons with Parkinson's

Parkinson's disease is a common, progressive and debilitating neurodegenerative disease. It currently cannot be prevented or cured.

18 Jun 2020

High-salt diet may modulate the gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

9 Jun 2020