Single Nucleotide Polymorphisms News and Research

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Exploring the Future of Breast Cancer Risk Assessment

An interview with Dr Gareth Evans about the future of breast cancer screening and the implementation of single nucleotide polymorphism (SNP) profiling.

1 Feb 2018

Genetic study identifies six new gene regions associated with type 1 diabetes in children

This article outlines a recent study which identified six novel gene regions in children who are at risk of type 1 diabetes.

17 Jan 2018

Scientists identify six new gene regions that may help treat type 1 diabetes

Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.

17 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.

14 Dec 2017

Genetic susceptibility to BD can increase suicide risk among people exposed to traumatic stress

Genetic susceptibility to bipolar disorder can increase the risk for suicide attempt, but only among those who also have experienced traumatic stress, reports a study published in the December 2017 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

4 Dec 2017

Research findings will help identify genetic causes of brain disorders

New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications.

27 Nov 2017

Gene variants appear to alter features of alcohol dose-response relationship

Although estimates vary, scientists believe that 50 to 64 percent of the risk of alcohol use disorders (AUDs) is inherited. One way to identify this risk is through a person's subjective response to alcohol.

14 Nov 2017

Dartmouth study uncovers three novel genetic biomarkers for lung cancer

Both environmental and genetic risk factors contribute to development of lung cancer. Tobacco smoking is the most well-known environmental risk factor associated with lung cancer. A Dartmouth research team led by Yafang Li, PhD, has conducted a study to display that gene-smoking interactions play important roles in the etiology of lung cancer.

26 Oct 2017

Adopting healthy diet can help reverse risk of high triglycerides, despite genetic predisposition

Triglycerides, a type of fat in the blood, are important for good health. But having high triglycerides might increase a person's risk of heart disease, and may be a sign of metabolic syndrome--a combination of high blood pressure, high blood sugar, and too much fat accumulation at the waist.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Study discovers new genetic risk loci linked to children's food allergies

What role do genes play in egg, milk, and nut allergies? A study published in Nature Communications, led by the Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, has found five genetic risk loci that point to the importance of skin and mucous membrane barriers and the immune system in the development of food allergies.

24 Oct 2017

Genes that determine skin color studied - new revelations

Human populations vary vastly in skin tones. European populations have been studied and some of the genes that determine skin color have been found. A latest study in a varied African population has found the specific and new genetic variants that could determine skin color and skin pigmentation. The study report is published in the journal Science.

16 Oct 2017

Myriad Genetics presents positive results of new hereditary cancer test at 36th annual conference of NSGC

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that two important studies will be featured in podium presentations at the 36th annual conference of the National Society of Genetic Counselors in Columbus, OH.

18 Sep 2017

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that it has launched riskScore, a new clinically validated precision medicine tool to enhance its myRisk Hereditary Cancer test. riskScore quantifies a woman's risk of developing breast cancer by combining genetic markers throughout the genome with her family and clinical history.

7 Sep 2017

Genetics of circadian rhythms found to have effect on migraine

People with a specific variation in the CLOCK gene have more migraines under financial stress. This work, the first time that the genetics of circadian rhythms has been shown to have an effect on migraine, is presented at the ECNP conference in Paris.

4 Sep 2017

Researchers uncover 16 genetic markers linked to decreased lifespan

The answer to how long each of us will live is partly encoded in our genome. Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date.

27 Jul 2017