Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

28 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

Metformin may reduce the risk of osteoarthritis

In a recent study published in JAMA Network Open, researchers in the United States (US) determined the risk of osteoarthritis (OA) and joint replacement among adults with type 2 diabetes (T2D) following metformin or sulfonylurea treatment.

27 Mar 2023

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Induced pluripotent stem cells offer great therapeutic potential and are a valuable tool for understanding how different diseases develop.

24 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Modulating the function of immune cells to recover aging muscle's regenerative capacity

Muscle is able to regenerate through a process that involves multiple steps and players, including the immune system.

23 Mar 2023

Study discovers a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers.

22 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

21 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

Hox genes control stem cells involved in forming and repairing bone

Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.

20 Mar 2023

Indiana CTSI secures $38 million NIH funding to advance health research

The Indiana Clinical and Translational Sciences Institute (CTSI) has secured nearly $38 million in renewed funding from the National Institutes of Health for the next seven years -; the fourth consecutive successful grant submission for the statewide research enterprise.

20 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Study sheds new insight into the dynamics of neural stem cell niche

When it comes to cell types, stem cells have unlimited potential – literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches.

16 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

Stem Cells News and Research

Further Reading

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Two distinct subtypes of insulin-producing beta cells identified

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

Metformin may reduce the risk of osteoarthritis

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Modulating the function of immune cells to recover aging muscle's regenerative capacity

Study discovers a protein controlling resistance to chemotherapy

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

Hox genes control stem cells involved in forming and repairing bone

Indiana CTSI secures $38 million NIH funding to advance health research

Scientists develop a marker for therapy response in acute myeloid leukemia

Study sheds new insight into the dynamics of neural stem cell niche

Bat stem cells reveal how bats survive in a virus-filled environment

Embryonic stem cells used to recreate thyroid cancer histotypes

A convergent coexpression approach identifies novel genes associated with autism

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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