Streptococcus pneumoniae News and Research

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Streptococcus pneumoniae, or Pneumococcus, is a very common bacterial infection in both industrialized and developing countries. In particular, young children and the elderly represent high-risk populations of developing pneumococcal infections. According to the WHO, the bacterium kills up to one million children under the age of five years each year worldwide. It accounts for many Bacterial Meningitis cases in adults and it is the most common cause of Bacteraemia, Pneumonia, Meningitis and Otitis media in young children.

How did trends in invasive bacterial diseases change during the first 2 years of the COVID-19 pandemic?

Researchers analyzed the surveillance data submitted by the Invasive Respiratory Infection Surveillance Consortium.

1 Aug 2023

Study: 82% of child deaths in low-income countries could be prevented

Eighty-two percent of child deaths in low-income countries could be prevented, according to a study from the international CHAMPS network published in JAMA Network Open.

26 Jul 2023

Machine learning's potential for rapid LRTI diagnosis

A team of researchers evaluated the use of prediction models in LRTI diagnosis.

17 Jul 2023

Mouse study offers clues to developing an effective vaccine for Klebsiella bacteria

A mouse study at Washington University School of Medicine in St. Louis points to data that could be key to developing an effective vaccine for the bacterium Klebsiella pneumoniae.

18 May 2023

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

The paper presents a systematic analysis of the global burden of bacterial antimicrobial resistance in 2019. The authors highlight the urgent need for action to address this growing public health threat.

23 Apr 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Chronological and biological age may be important determinants of vaccine-preventable outcomes

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Parsing chronological and biological age effects on vaccine responses."

27 Mar 2023

Exploring the complexities of antimicrobial resistance forecasting

Researchers highlight the need for prioritizing research on antimicrobial-resistant organism forecasting.

23 Mar 2023

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers -; the meninges -; and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

SARS-CoV-2 infection does not appear to influence pneumococcal colonization in the upper respiratory tract.

28 Feb 2023

Study reveals how a subset of lung T regulatory cells protects against deadly pneumococcal disease

A new study by University of Liverpool researchers reveals how resistance to bacteraemic pneumonia is provided by a unique subset of lung T regulatory cells.

8 Feb 2023

Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters

Researchers from the United States evaluated the efficacy and immunogenicity of an intranasal messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine against SARS-CoV-2 using a hamster model.

16 Jan 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Study on bacterial infection in older individuals

The older population is prone to microbial infections, which can lead to death. Hence, it is important to understand why this group is vulnerable to microbial infection, especially bacterial infection. A recent Scientific Reports study linked data from two sources to understand the determining factors for microbial infection in the older population in the UK.

11 Jan 2023

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Patients with rheumatoid arthritis, lupus, and other rheumatic conditions are more at risk for complications and death from pneumonia, meningitis, and other bacterial infections, yet most have not been vaccinated against infection.

29 Dec 2022

Withdrawal of COVID-19 mitigation measures resulted in a rebound in Streptococcus pneumoniae cases in Germany

Researchers from Germany conducted a population-based surveillance study to ascertain the etiology of community acquired pneumonia (CAP) during the re-emergence of viral and bacterial respiratory diseases after the relaxation of coronavirus disease 2019 (COVID-19) containment and mitigation measures.

20 Dec 2022

Modulation of insect immunity to control vector-borne diseases

Discussed the current research on the role of molecular mechanisms in mediating immune priming in insects and regulating vector-borne disease transmission.

19 Dec 2022