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Scientist develops way to deliver promising genetic tool into living cells

By exploiting an HIV protein that readily traverses cell membranes, Carnegie Mellon University scientists have developed a new way to introduce a gene-like molecule called a peptide nucleic acid (PNA) directly into live mammalian cells, including human embryonic stem (ES) cells.

6 Dec 2004

MRI reveals similarities between the human and chimpanzee brain

New MRI-based studies present more evidence that the brains of chimpanzees are human-like in terms of the relationships among brain asymmetry, handedness and language, according to research undertaken at the Yerkes National Primate Research Center in Atlanta.

6 Dec 2004

Canadian experts gather to address emerging issues in immunization

More than 800 physicians, nurses, public health experts and researchers are gathering in Montreal this week for the sixth Canadian Immunization Conference, running Dec. 5-8, 2004. The conference is being hosted by the Public Health Agency of Canada and the Canadian Paediatric Society.

6 Dec 2004

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

The hopes of many that ALS (commonly referred to as Lou Gehrig's disease) will one day be a disease of the past, studied in medical textbooks, conquered by the dedication of those who have worked tirelessly to eradicate it might be realized in our lifetime.

6 Dec 2004

New technologies boost immunisation rates, safety

As global health leaders struggle to meet the United Nations goal of reducing mortality among the world's poorest children, vaccines are attracting more and more attention. The purchase of the vaccine is just the beginning, however, as the effectiveness of a vaccine is only as good as its delivery system.

6 Dec 2004

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Telik, Inc. reported positive interim data from a Phase 2 trial of its Telintra (TLK199) drug candidate in myelodysplastic syndrome (MDS). The data were reported in two presentations at the annual meeting of the American Society of Hematology in San Diego.

5 Dec 2004

Genasense shown to enhance the anti-lymphoma activity of Velcade and Rituxan

Genta Incorporated announced that two new studies have shown that Genasense (oblimersen sodium) Injection, the Company's lead anticancer drug, showed synergistic activity with both bortezomib (Velcade; Millennium Pharmaceuticals, Inc.) and rituximab (Rituxan; Genentech, Idec) in experimental models of B-cell non-Hodgkin's lymphoma (NHL).

5 Dec 2004

Implications of twin, triplet and quadruplet pregnancies on mothers

More women giving birth in their later years has given rise to fertility treatments which has in turn led to what can be described as an explosion in twin, triplets and quadruplet pregnancies.

4 Dec 2004

Scene-of-the-crime DNA analysis is moving a step closer

Currently DNA analysis is both time-consuming and expensive, but researchers at the Polymer Electronics Research Centre (PERC), within the Faculty of Science and the Faculty of Medical and Health Sciences, hope to change that by inventing a system that provides direct, real-time detection of DNA.

4 Dec 2004

More than 11 million children in developing countries die every year from preventable illness

More than 11 million children in developing countries die every year from preventable illness, while as many as 500 000 women don't survive during pregnancy or childbirth. More than 39 million people are living with HIV/AIDS and the epidemic is growing.

4 Dec 2004

Fossil record of the human immune system reveals antibodies that block cancer metastasis

A team of researchers at The Scripps Research Institute has reconstructed the "fossil record" of the immune systems of a group of human cancer patients to investigate if they had ever produced antibodies against their disease.

4 Dec 2004

A vitamin B pill that drastically lowers blood levels of homocysteine could one day be used to prevent dementia

High blood levels of homocysteine are a risk factor for stroke and dementia, including Alzheimer’s disease. Raised levels damage nerves and blood vessels, and lead to a loss of brain tissue in patients.

4 Dec 2004

FDA approval of cream to treat bacterial vaginosis

KV Pharmaceutical Company has announced that it has received approval from the United States Food and Drug Administration (FDA) to market Clindesse (clindamycin phosphate) Vaginal Cream, 2%, a single-dose prescription cream therapy indicated to treat bacterial vaginosis ("BV").

3 Dec 2004

Important step in understanding why some of us can eat fatty foods and not suffer from cardiac disease

Doctors and their patients have puzzled over why certain cholesterol-lowering drugs work better in some people than others. In research results published in the December issue of the journal Nature Genetics, the common minnow helps provide an answer.

2 Dec 2004

Tofu-based biomaterial that can help mend broken bones

A new Tofu-based biomaterial that can help mend broken bones and damaged tissues is being developed thanks to an investment of £149,000 from NESTA (the National Endowment for Science, Technology and the Arts), the organization that champions UK creativity and innovation.

2 Dec 2004

Smoking habits during pregnancy may cause genetic instability in the foetus

The Spanish Pediatrics Association has recently awarded the Pediatrics laboratory at the University of Navarre for a research into tobacco and foetal genetic instability.

2 Dec 2004

Cancer Research Technology grants AstraZeneca an exclusive license to a key patent

Cancer Research Technology Limited has announced that AstraZeneca has licensed exclusive worldwide rights to a patent family relating to a nuclear receptor/co-activator binding motif.

1 Dec 2004

World Health Organization is reinstating two antiretrovirals manufactured by Cipla Ltd

The two medicines (which are used in the treatment of AIDS) had been delisted by WHO in May this year due to non-compliance with international standards at the contract research organizations (CROs) hired by Cipla to conduct bioequivalence tests on the products.

30 Nov 2004

Rimonabant could be safer for treating obesity than previous weight-loss drugs

ECRI, a nonprofit health services research agency, recently published a Health Technology Forecast profile on a novel pharmaceutical agent that is in development for the treatment of obesity.

30 Nov 2004

Eliminating racial disparities would save many more lives than technological advances

The number of lives saved by advances in medical technology over the past decade pales in comparison to the lives lost due to racial inequities in the health care system.

29 Nov 2004

Technology News and Research

Scientist develops way to deliver promising genetic tool into living cells

MRI reveals similarities between the human and chimpanzee brain

Canadian experts gather to address emerging issues in immunization

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

New technologies boost immunisation rates, safety

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Genasense shown to enhance the anti-lymphoma activity of Velcade and Rituxan

Implications of twin, triplet and quadruplet pregnancies on mothers

Scene-of-the-crime DNA analysis is moving a step closer

More than 11 million children in developing countries die every year from preventable illness

Fossil record of the human immune system reveals antibodies that block cancer metastasis

A vitamin B pill that drastically lowers blood levels of homocysteine could one day be used to prevent dementia

FDA approval of cream to treat bacterial vaginosis

Important step in understanding why some of us can eat fatty foods and not suffer from cardiac disease

Tofu-based biomaterial that can help mend broken bones

Smoking habits during pregnancy may cause genetic instability in the foetus

Cancer Research Technology grants AstraZeneca an exclusive license to a key patent

World Health Organization is reinstating two antiretrovirals manufactured by Cipla Ltd

Rimonabant could be safer for treating obesity than previous weight-loss drugs

Eliminating racial disparities would save many more lives than technological advances

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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