Therapeutics News and Research

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BRIT1 gene plays a pivotal role in DNA damage detection and repair

A single gene plays a pivotal role launching two DNA damage detection and repair pathways in the human genome, suggesting that it functions as a previously unidentified tumor suppressor gene.

3 Aug 2006

Better understanding of intravenous immunoglobulin

For years, researchers have struggled to understand how IVIG worked. It's ability to treat autoimmune diseases seemed to bean apparent contradiction.

3 Aug 2006

New therapeutics for cancer

A team of scientists at the University of Liverpool has secured the services of the National Biomanufacturing Centre (NBC) to develop and manufacture antibodies against a novel cancer antigen.

1 Aug 2006

HHS to stockpile Anthrax immune globulin

The Department of Health and Human Services (HHS) has announced it will purchase 10,000 therapeutic courses of treatment of Anthrax Immune Globulin (AIG) from Cangene Corporation of Winnipeg, Manitoba, Canada for a total of $143,833,719.

30 Jul 2006

Scientists characterize structure of calbindin-D28K

Scientists at North Carolina State University have effectively lifted the veil from an important protein that is linked to the prevention of neurodegenerative diseases like Alzheimer's and Huntington's.

26 Jul 2006

Cigarette smoking appears to promote the consumption of alcohol

Nicotine can reduce blood alcohol concentrations (BACs) at dosage levels that could be achieved by human smokers.

25 Jul 2006

3D model reveals secrets of metastasis

A cancer cell breaks away from a primary tumor and settles in a new location, where it once again divides.

12 Jul 2006

First trial to investigate effects of cannabinoids on progression of multiple sclerosis

Clinicians from across the UK have now embarked on the world's first trial to investigate whether cannabis derivatives could play a role in slowing the progression of multiple sclerosis.

11 Jul 2006

Scientists discover promising new therapeutic target for heart disease

Scientists at the Boston Biomedical Research Institute identified Puma (p53 upregulated modulator of apoptosis) as a potential new target for the therapeutic intervention of heart disease.

10 Jul 2006

New polymer-lipid hybrid nanoparticle

A novel combination of lipids, a negatively charged polymer, and the anticancer drug doxorubicin has yielded a new nanoparticle that can kill breast cancer cells that are normally resistant to this drug.

3 Jul 2006

Multiple cancer biomarkers detected simultaneously

Polymerase chain reaction (PCR) technology revolutionized diagnostic medicine and basic research through its ability to amplify and detect minute amounts of specific DNA sequences.

3 Jul 2006

Objections to Kreutzer-Limmer patent by Sirna Therapeutics accepted by the European Patent Office

Sirna Therapeutics has announced that its objections to the Kreutzer-Limmer patent in Europe were accepted by the European Patent Office.

29 Jun 2006

New immunology research collaboration established

Singapore's Agency forScience, Technology and Research (A*STAR) and The Australian National University establish immunology research collaboration.

27 Jun 2006

New hope for Huntington disease cure

Researchers provide ground-breaking evidence for a cure for Huntington disease in a mouse offering hope that this disease can be relieved in humans.

18 Jun 2006

Fly research sheds light on sleep regulation and its role in memory

Researchers at the University of Pennsylvania School of Medicine have discovered that a brain region previously known for its role in learning and memory also serves as the location of sleep regulation in fruit flies.

18 Jun 2006

COX enzymes work together in ways that suggest new biological roles

COX enzymes - well-known for their contrasting role in cardiovascular biology - interact physically to form a previously unrecognized biochemical partnership and function in the development of blood vessels in a mouse model.

9 Jun 2006

Markey Cancer Center receives approval to test cancer drug DB-67

Tom Burke died of colon cancer only a few years ago, but not before he helped create a new drug to fight cancer.

8 Jun 2006

Costly IVIg could be replaced with synthetic blood product

Patients suffering from a life-threatening bleeding disorder are closer to having access to a more effective treatment.

1 Jun 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

Discovery of two gene variants associated with increased risk for early heart attack

Scientists at University of California - San Francisco (UCSF), Celera Genomics and The Cleveland Clinic have discovered two gene variants associated with a significantly increased risk for early heart attack, or myocardial infarction (MI).

12 May 2006