Transcriptomics News and Research

RSS

Insilico Medicine's PandaOmics Box enhances drug discovery with advanced AI capabilities

The development of innovative medicines is an expensive, time-consuming and risky business. On average, it usually takes at least a decade and billions of dollars to bring a new drug from project initiation to approval.

25 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Creating the first genetically susceptible mice for late-onset Alzheimer's

Mice don't get Alzheimer's-;and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.

24 Jul 2024

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

A study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra University, has identified a group of small molecules exclusive to liver tumors that could be key to developing cancer vaccines.

11 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

New AI tool can help select the most suitable treatment for cancer patients

A new artificial intelligence (AI) tool that can help to select the most suitable treatment for cancer patients has been developed by researchers at The Australian National University (ANU).

3 Jul 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

Multi-regional sampling uncovers hidden complexity in liver cancer

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation Singapore (NRF) has discovered unexpected molecular heterogeneity even within the same liver tumors. More than 40% of HCC harbors more than one molecular subtype within the same tumor and in these, the clinical outcomes for the patients are best predicted by the most aggressive subtype.

25 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

Artificial variants of Withanolides act highly specifically against leukemia cells

Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells.

21 Jun 2024

New cellular atlas revolutionizes understanding of spinal cord injury

Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuries-;mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'.

19 Jun 2024

New insights into blood precursors of pathogenic macrophages in RA

The exact origin and precursor differentiation route of tissue macrophages remains controversial. At the 2024 congress of EULAR - The European Alliance of Associations for Rheumatology - new work sheds light on blood precursors of pathogenic tissue macrophages.

13 Jun 2024

Transcriptomics News and Research

Insilico Medicine's PandaOmics Box enhances drug discovery with advanced AI capabilities

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Creating the first genetically susceptible mice for late-onset Alzheimer's

Group of small molecules exclusive to liver tumors could be key to developing cancer vaccines

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

New AI tool can help select the most suitable treatment for cancer patients

Open-source platform enables high-definition spatial transcriptomics

Multi-regional sampling uncovers hidden complexity in liver cancer

WEHI study reveals new methods in detecting necroptosis

Artificial variants of Withanolides act highly specifically against leukemia cells

New cellular atlas revolutionizes understanding of spinal cord injury

New insights into blood precursors of pathogenic macrophages in RA

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

Father's diet before conception can impact children's metabolic health, study finds

New computational method analyzes complex tissue data to transform treatment of disease

Ohio State creates user-friendly repository to help study Alzheimer's disease

STew: A new method for unveiling the spatial fingerprint of diseases

Single-cell analysis reveals insights into immune responses during xenotransplantation

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

FAU researchers receive grants to tackle Alzheimer's disease

Omics eBook

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

Latest News