Transcriptomics News and Research

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Alternative gene splicing can impact the risk for alcohol use disorder

Researchers at Indiana University School of Medicine have discovered alternative gene splicing, which occurs during gene expression, can impact a person's risk of alcohol use disorder (AUD).

30 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Can beer intake improve heart health following oxidative injury?

Researchers examined the impact of antioxidants found in fermented beverages on tissue transcriptomics.

16 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Cannabis product authenticity: a metabolomic big data approach

Researchers examined the aspects of the authentomics of cannabis products.

5 May 2023

The Evolution of Molecular Biology

In this interview, Istvan Szatmari, the Head of The Genomic Core Facility at the Department of Biochemistry and Molecular Biology, talks to NewsMed about the evolution of Molecular Biology.

From MGI 4 May 2023

MGI and South Australian Genomics Centre Introduce DNBSEQ-T7 to Supercharge Genomics Research in Australia

Brisbane, Australia 27th April 2023 - MGI and South Australian Genomics Centre (SAGC) are proud to announce their joint efforts to advance genomics research in Australia by introducing the country's first commercial ultra-high throughput sequencer DNBSEQ-T7*, through MGI's local distributor Decode Science.

From MGI 27 Apr 2023

Sphere Fluidics begins work with partners on 3DSecret program to investigate mechanisms of metastasis in cancer

Sphere Fluidics announced its involvement in 3DSecret.

From Sphere Fluidics 24 Apr 2023

Cornell receives $9.5 million NIH grant for chronic fatigue research

A Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a five-year, $9.5 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Disease – funding that will enable experts from disparate fields to work together on the mysterious and debilitating condition.

11 Apr 2023

Study proposes a roadmap to understand the extent of regeneration in the human brain

Is our brain able to regenerate? And can we harness this regenerative potential during aging or in neurodegenerative conditions? These questions sparked intense controversy within the field of neuroscience for many years.

3 Apr 2023

Researchers develop new method to make rare cell types and disease patterns visible in tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

31 Mar 2023

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

Machine learning applications for the diagnosis, treatment and prognosis of cancer

Researchers review the application of machine learning in improving cancer diagnosis, treatment, and prognosis.

19 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.