Umbilical Cord News and Research

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The umbilical cord is the structure that attaches the fetus to the placenta and acts as the medium through which nutrients, gases and waste products travel between the mother and the fetus.

Early blood test could detect birth asphyxia

An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy.

4 Aug 2020

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Now, a new study published on the preprint server medRxiv* in July 2020 reveals evidence of placental infection and hypoxia, despite the lack of serious symptoms in the mother.

16 Jul 2020

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood - a readily available source of stem cells - safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

14 Jul 2020

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

Scientists have new evidence that overactive neutrophils--a common type of circulating immune cell--may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19.

29 Jun 2020

New study defines the transmission of COVID-19 from mother to child

UC Davis Health researchers took a critical step in defining the possible paths for the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) causing COVID-19 to get transmitted from the mother to her newborn baby. The mother to fetal transmission is known as "vertical" transmission.

24 Jun 2020

Researchers report a key breakthrough to help protect newborns from brain damage

Oxygen deprivation can be the worst start to a newborn's life, resulting in brain damage, epilepsy, developmental delays and death.

23 Jun 2020

Novel vaccine platform against COVID-19 based on engineered human mesenchymal stem cells

In a recent groundbreaking bioRxiv paper, Chinese researchers describe a novel approach towards coronavirus disease (COVID-19) vaccine design based on engineered human mesenchymal stem cells, with favorable and promising antibody response.

22 Jun 2020

Early respiratory distress syndrome caused by SARS-CoV-2 in a newborn

A recent case report from the researchers at the University of São Paulo, published in the journal CLINICS, shows how newborns can also be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and develop serious symptoms, even though the most likely route of infection in such cases is still not completely clear.

14 Jun 2020

Texas Heart Institute and 7 Hills Pharma receive $1.9 million to improve stem cell transplants

The Texas Heart Institute and 7 Hills Pharma received a $1.9 million, Phase II STTR (R42) grant from the National Heart Lung Blood Institute to advance further their lead product 7HP349, a novel integrin activator, to define the optimal dosing schedule for cord blood transplant along with a focus on development and production of a formulation that meets safety standards for filing an IND application with the FDA.

12 Jun 2020

Does COVID-19 injure the placenta of pregnant women?

News-Medical speaks to Dr. Jeffery Goldstein about whether COVID-19 is damaging the placentas of pregnant women and what women can do to protect themselves.

12 Jun 2020

COVID-19 appears to attack the placenta in pregnant women

Pregnant women should take extra precautions amid the coronavirus pandemic. A new study shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), attacks the placenta.

26 May 2020

Study finds evidence of injury in placentas from COVID-19-positive pregnant women

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study.

22 May 2020

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Shortly after the explosion in microcephaly cases caused by Zika virus in Brazil in 2015-16, several scientific studies were published with evidence that the pathogen is capable of crossing the human placenta, the organ that keeps the fetus connected to the mother's body during pregnancy.

20 May 2020

Study shows it is safe to give antibiotics to mothers after umbilical cord clamping in C-sections, to avoid exposure of newborns

Research shows it is safe to give antibiotics to mothers after umbilical clamping in C section, to avoid exposure of the baby.

17 Apr 2020

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

After a lightening round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells to block the life-threatening lung inflammation that accompanies severe cases of COVID-19.

11 Apr 2020

Umbilical Cord News and Research

Further Reading

Early blood test could detect birth asphyxia

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

New study defines the transmission of COVID-19 from mother to child

Researchers report a key breakthrough to help protect newborns from brain damage

Novel vaccine platform against COVID-19 based on engineered human mesenchymal stem cells

Early respiratory distress syndrome caused by SARS-CoV-2 in a newborn

Texas Heart Institute and 7 Hills Pharma receive $1.9 million to improve stem cell transplants

Does COVID-19 injure the placenta of pregnant women?

COVID-19 appears to attack the placenta in pregnant women

Study finds evidence of injury in placentas from COVID-19-positive pregnant women

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Study shows it is safe to give antibiotics to mothers after umbilical cord clamping in C-sections, to avoid exposure of newborns

New clinical trial launches to test efficacy of cell therapy for severe COVID-19 cases

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Can novel coronavirus affect pregnant women and their babies?

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

Length of pregnancy related to chemical DNA changes in newborns

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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