Vasculature News and Research

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Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Telerobotic system can help surgeons quickly and remotely treat a stroke or aneurysm

MIT engineers have developed a telerobotic system to help surgeons quickly and remotely treat patients experiencing a stroke or aneurysm.

13 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

Insights into the pathophysiology of NeuroCOVID

A new study describes the neurological features of COVID-19, both short- and long-term.

6 Apr 2022

Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome

Researchers developed 1,2-dimpalmiyristoyl-sn-glycero-3-phosphocholine liposomes co-loaded with methylprednisolone and N-acetyl cysteine to treat acute respiratory distress syndrome in vivo.

31 Mar 2022

Yale researchers uncover how to control the blood-brain barrier with a molecule

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

16 Mar 2022

Researchers develop new cranial window system for long-term studies of brain activity

Bilal Haider is studying how multiple areas of the brain work together for visual perception. This could help researchers understand if neural activity "traffic jams" underlie all kinds of visual impairments: from running a red light when visual attention is elsewhere, to shedding light on the autism-affected brain.

11 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

New 3D model of living brain cancer overcomes a major challenge in tissue engineering

As a potential alternative for drug testing without lab animals, researchers at KTH Royal Institute of Technology developed and successfully tested a 3D model of living brain cancer that surmounts one of the biggest challenges in tissue engineering.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

3D model of living brain cancer developed as a potential alternative for drug testing without animals

23 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Hyaluronic acid, or HA, is a known presence in pancreatic tumors, but a new study from researchers at the University of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.