Vasculature News and Research

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Physical modulation of the tumor microenvironment to enhance cancer therapy

Announcing a new article publication for BIO Integration journal. The tumor microenvironment (TME) has a crucial role in tumor development, metastasis, and recurrence.

19 Jul 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Vascular changes in pre-symptomatic stages of Huntington's disease offer new predictive potential

The genetic disease Huntington's not only affects nerve cells in the brain but also has widespread effects on microscopic blood vessels according to research.

10 Jun 2024

New antioxidant biomaterial may provide relief to people living with chronic pancreatitis

Northwestern University researchers have developed a new antioxidant biomaterial that someday could provide much-needed relief to people living with chronic pancreatitis.

7 Jun 2024

Targeting macrophages for enhanced vascular integrity and healing in ischemic injuries

Innate immune cells including macrophages and neutrophils have unique properties that allows them to quickly accumulate in large numbers at the site of infection or injury.

6 Jun 2024

Study reveals lung vascular differences in growth-restricted fetuses

If during a pregnancy a fetus grows below normal thresholds, at each week of gestation there is an increased risk that some of its organs may not develop properly, which can adversely affect the baby's health after birth.

17 May 2024

New study finds Sfrp1 as a potential therapeutic target in cancer treatment

Cancer is a leading cause of death globally. One of the primary reasons why cancer is such a deadly disease is the ability of cancer cells to become drug-resistant.

15 May 2024

Interpreter access associated with Heart School participation among foreign-born post-heart attack patients

After a heart attack, foreign-born people are less likely to attend a relapse-preventing Heart School than native-born patients.

15 May 2024

Anger damages blood vessel function, raising heart disease risk

A recent study in the Journal of the American Heart Association reveals that provoked anger, but not sadness or anxiety, acutely impairs endothelial function, shedding light on the link between anger and cardiovascular events.

2 May 2024

Discovery of new vascular cell type may pave way for novel strategies to treat cardiovascular diseases

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

A recent breakthrough study from the lab of Tanya Kalin, MD, PhD, professor of Child Health and Internal Medicine at the University of Arizona College of Medicine – Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung cancers.

16 Apr 2024

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease.

10 Apr 2024

Obesity and high-fat diets linked to accelerated aging in brain blood vessels

A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain.

7 Apr 2024

Blast exposure can cause intestinal permeability, study shows

A study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause intestinal permeability, a condition that can lead to gut bacteria entering the bloodstream and causing problems in other parts of the body.

5 Apr 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024