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Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

A study by the Neuropharmacology Laboratory-NeuroPhar of the Department of Experimental and Health Sciences at UPF reveals the involvement of the endocannabinoid system in cognitive disorders in mouse models of Down syndrome.

7 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

Large genetic analysis of impulsiveness reveals links with psychiatric disorders

Impulsiveness and substance use share a genetic basis, according to genome-wide association studies published in JNeurosci by academic and industry researchers.

From Society for Neuroscience 5 Feb 2019

Study sheds light on the genetic causes of tumors in salivary glands

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland.

31 Jan 2019

Researchers discover how transcription factors find specific loci within DNA

Bioengineering experts have discovered that transcription factors which bind non-specifically to mitotic chromosomes are more efficient at finding their binding site within DNA during interphase.

30 Jan 2019

Study shows that aging and chronic diseases share common genetic factors

The global population aged 60 or over is growing faster than all younger age groups and faces the tide of chronic diseases threatening their quality of life and posing challenges to healthcare and economy systems.

30 Jan 2019

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

RNA-induced gene fusion can occur in mammalian cells, reveals study

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome.

29 Jan 2019

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

The Damon Runyon Cancer Research Foundation announced that nine scientists with novel approaches to fighting cancer have been named 2019 recipients of the Damon Runyon-Rachleff Innovation Award.

24 Jan 2019

Novel therapeutic approach for treatment of leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia.

24 Jan 2019

Researchers uncover new role of heterochromatin in maintaining chromosomal integrity

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes in the structure of chromosomes, known as gross chromosomal rearrangements, can result in cell death or genetic diseases such as cancer.

24 Jan 2019

Cellular recycling process may prevent cancer initiation, finds study

Just as plastic tips protect the ends of shoelaces and keep them from fraying when we tie them, molecular tips called telomeres protect the ends of chromosomes and keep them from fusing when cells continually divide and duplicate their DNA.

24 Jan 2019

Study sheds new light on male infertility

Hope has emerged for infertile men as scientists at Newcastle University have understood the importance of a gene in regulating the production of fully-functioning sperm.

24 Jan 2019

New research focuses on noise sensitivity and general fearfulness of canine behavior

Researchers in the Hannes Lohi research group in the University of Helsinki focused on two forms of canine fearfulness: noise sensitivity and general fearfulness.

24 Jan 2019

Experimental drug can positively modify key characteristic behavior in FXS patients

Researchers at MIND Institute at UC Davis and Rush University Medical Center have found that mavoglurant, an experimental drug known as a mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome.

22 Jan 2019

Scientists aim to find genetic causes of developmental abnormalities in the vagina and uterus

A percentage of females are born with a missing or underdeveloped vagina and uterus, and scientists are working to analyze the genes of hundreds of them to get a better idea about causes, improve genetic counseling and ideally treatment.

22 Jan 2019

Unexpected connection found between feeding and memory centers of the brain

The search for a mechanism that could explain how the protein complex NCOR1/2 regulates memory has revealed an unexpected connection between the lateral hypothalamus and the hippocampus, the feeding and the memory centers of the brain, respectively.

21 Jan 2019

Researchers discover how cancer cells avoid genetic meltdown

A team of scientists have shed light on how cancer cell populations avoid genetic meltdown, despite the rapid accumulation of harmful mutations.

15 Jan 2019

Researchers identify genetic risk factor for atypical heart attack in women

New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women.

7 Jan 2019

Research reveals factors at play in genetic incompatibility of different species

Most evolutionary biologists distinguish one species from another based on reproductivity: members of different species either won't or can't mate with one another, or, if they do, the resulting offspring are often sterile, unviable, or suffer some other sort of reduced fitness.

4 Jan 2019

X chromosome News and Research

Cannabinoid receptor type 1 appears to be potential target to treat Down syndrome

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Large genetic analysis of impulsiveness reveals links with psychiatric disorders

Study sheds light on the genetic causes of tumors in salivary glands

Researchers discover how transcription factors find specific loci within DNA

Study shows that aging and chronic diseases share common genetic factors

Big data opens door for characterizing immunity-related genome in Japanese population

RNA-induced gene fusion can occur in mammalian cells, reveals study

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

Novel therapeutic approach for treatment of leukemia

Researchers uncover new role of heterochromatin in maintaining chromosomal integrity

Cellular recycling process may prevent cancer initiation, finds study

Study sheds new light on male infertility

New research focuses on noise sensitivity and general fearfulness of canine behavior

Experimental drug can positively modify key characteristic behavior in FXS patients

Scientists aim to find genetic causes of developmental abnormalities in the vagina and uterus

Unexpected connection found between feeding and memory centers of the brain

Researchers discover how cancer cells avoid genetic meltdown

Researchers identify genetic risk factor for atypical heart attack in women

Research reveals factors at play in genetic incompatibility of different species

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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