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Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

The scope of the activity of neuropeptides is remarkably broad. For example, neuropeptides are involved in pain control, mood/depression/eating disorders, social and emotional behaviour, body weight, drug abuse, stress, reproduction, motor control, memory, and in maintaining neuronal health when they are stressed.

From Pittcon 14 Jan 2016

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

Cornell researchers have discovered potent cancer-killing proteins that can travel by white blood cells to kill tumors in the bloodstream of mice with metastatic prostate cancer. The breakthrough study will be published Feb. 10 as the cover article in the Journal of Controlled Release.

13 Jan 2016

TRL becomes primary distributor of Kirkstall's QuasiVivo system in the US and Canada

Triangle Research Labs, LLC and Kirkstall, Ltd, are pleased to announce TRL as the primary distributor of Kirkstall's 3-D cell fluidic culture system, QuasiVivo, in the US and Canada.

12 Jan 2016

Combining NELL-1 with BMP2 therapy may promote bone development

Bone morphogenetic protein-2 (BMP2) is used clinically to promote bone repair. However, the high BMP2 concentrations required to stimulate bone growth in humans may produce life-threatening adverse effects such as cervical swelling in spinal fusion procedures, a problem that prompted an FDA warning in 2008.

7 Jan 2016

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions

From Beckman Coulter Life Sciences - Flow Cytometry 5 Jan 2016

Sugary Western diet may increase risk of breast cancer and metastasis to the lungs

The high amounts of dietary sugar in the typical Western diet may increase the risk of breast cancer and metastasis to the lungs, according to a study at The University of Texas MD Anderson Cancer Center.

4 Jan 2016

Study unravels mechanisms by which saffron-based crocin prevents liver cancer

Liver cancer remains among the leading causes of cancer-related death worldwide. New study lead by UAE University Prof. Amr Amin unravels mechanisms by which saffron-based 'crocin' protects against liver cancer.

4 Jan 2016

Immune enters into exclusive license with Atlante Biotech for new format of bispecific antibodies

Immune Pharmaceuticals Inc. a clinical-stage company developing novel therapies for the treatment of immuno-inflammatory diseases and cancer, today announced it has entered into an exclusive license with Atlante Biotech SAS, to the patents and know-how for a new format of bispecific antibodies.

29 Dec 2015

Collaborative team to determine mechanisms that cause traumatic brain injuries due to shockwaves

Nearly 300,000 soldiers have returned from service in Iraq and Afghanistan with symptoms of traumatic brain injuries due to blast shockwaves. Such injuries often go untreated because they are undetected by brain scans despite the symptoms' presence.

24 Dec 2015

New footage shows how AIDS vaccine candidate recruits immune cells to destroy infected cells

Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response.

23 Dec 2015

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

Immune suppressor cells called MDSCs (myeloid-derived suppressor cells) may be important in developing treatments for advanced prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center.

22 Dec 2015

New funding supports research on new and improved drug treatments for tuberculosis, malaria

University of Toronto and McGill University scientists are leading an international partnership to discover new and improved drug treatments for tuberculosis, malaria and neglected tropical diseases -- thanks to a contribution from Merck Canada Inc., as well as an additional $5 million supplement to a grant from the Bill & Melinda Gates Foundation.

17 Dec 2015

Researchers trace origins of early abnormal brain overgrowth in ASD

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

14 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

Researchers discover 'triple attack' technique to target liver cancer tumors

In an interdisciplinary collaboration between prominent academic and industry investigators, researchers have discovered a novel method for repositioning an FDA-approved anti-cancer compound so it can specifically target liver cancer tumors. A 'triple attack' technique combining chemotherapy, thermal ablation, and hyperthermia provided a highly targeted, yet minimally invasive approach.

8 Dec 2015

Study provides new insights into relationship between taste, behavior

Evolutionary conserved brainstem circuits are the first relay for gustatory information in the vertebrate brain. While the brainstem circuits act as our life support system and they mediate vital taste related behaviors, the principles of gustatory computations in these circuits are poorly understood.

8 Dec 2015

Researchers unveil relationship between ovarian cancer and obesity

Ovarian cancer is a deadly disease, one that's hard to detect until it has progressed significantly. More than 75 percent of women diagnosed with ovarian cancer have metastasis at the time of diagnosis, resulting in a low five-year survival rate of less than 30 percent.

8 Dec 2015

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

A phage is a virus that infects a bacterium. People often get very confused about what the difference is between a virus and a bacterium. A virus, like a bacterium, is also a microorganism, but unlike bacteria, it needs to have a host to be able to replicate and propagate.

2 Dec 2015

Researchers develop more precise way to control differentiation of stem cells into bone cells

Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences and The Wyss Institute for Biologically Inspired Engineering have developed a new, more precise way to control the differentiation of stem cells into bone cells.

1 Dec 2015

Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

in vivo News and Research

Determining Ectopeptidase Activity: An Interview with Professor Stephen Weber, University of Pittsburgh

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

TRL becomes primary distributor of Kirkstall's QuasiVivo system in the US and Canada

Combining NELL-1 with BMP2 therapy may promote bone development

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

Sugary Western diet may increase risk of breast cancer and metastasis to the lungs

Study unravels mechanisms by which saffron-based crocin prevents liver cancer

Immune enters into exclusive license with Atlante Biotech for new format of bispecific antibodies

Collaborative team to determine mechanisms that cause traumatic brain injuries due to shockwaves

New footage shows how AIDS vaccine candidate recruits immune cells to destroy infected cells

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

New funding supports research on new and improved drug treatments for tuberculosis, malaria

Researchers trace origins of early abnormal brain overgrowth in ASD

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Researchers discover 'triple attack' technique to target liver cancer tumors

Study provides new insights into relationship between taste, behavior

Researchers unveil relationship between ovarian cancer and obesity

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

Researchers develop more precise way to control differentiation of stem cells into bone cells

Researchers reveal new technique to grow human hepatocytes in the laboratory

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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