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Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D).

17 Feb 2015

Study findings could help scientists better design silicon materials to improve chemotherapy drug delivery

A team of Israeli and American researchers have found that silicon nanomaterials used for the localized delivery of chemotherapy drugs behave differently in cancerous tumors than they do in healthy tissues. The findings could help scientists better design such materials to facilitate the controlled and targeted release of the chemotherapy drugs to tumors.

16 Feb 2015

AXT adds TriFoil imaging products to their preclinical imaging portfolio

TriFoils flagship is the Triumph tri-modal imaging system that incorporates PET/SPECT and CT technologies all in a single instrument. It has a bore size of 15cm and an axial view of 30cm making ideal for small animal studies.

From MR Solutions 13 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

AXT establishes preclinical imaging portfolio with MR solutions product lines

To coincide with the start of Lorne Cancer conference, AXT are proud to announce the commencement of their distributorship with MR SOLUTIONS, a world leader in the development of innovative preclinical imaging solutions

From MR Solutions 11 Feb 2015

New findings could pave way to develop drug therapies for necrosis-related diseases

Strokes, heart attacks and traumatic brain injuries are separate diseases with certain shared pathologies that achieve a common end - cell death and human injury due to hypoxia, or lack of oxygen.

9 Feb 2015

New study provides better understanding of how stem cells give rise to tumors

Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a precise stem cell signaling process that can lead to intestinal tumors if disrupted. The findings add to our understanding of how stem cells give rise to tumors and identify specific stem cell molecules that may be targeted to prevent the onset, progression, and recurrence of intestinal cancers.

6 Feb 2015

Recipients of The 2015 Protein Society Awards announced

The Protein Society, the premiere international society dedicated to supporting protein research, announces the winners of The 2015 Protein Society Awards. The awards will be conferred at the 29th Annual Symposium of The Protein Society (July 22-25, 2015, Barcelona, Spain).

5 Feb 2015

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

A novel Electron Paramagnetic Resonance (EPR) oximetry technique will help clinicians directly measure oxygen and schedule treatments at times of high oxygen levels in cancer and stroke patients to improve outcomes, The EPR team at Dartmouth's Geisel School of Medicine has found.

5 Feb 2015

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders.

31 Jan 2015

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.

31 Jan 2015

Micromotor fueled by stomach acid effectively delivers gold nanoparticles

Researchers at the University of California, San Diego have shown that a micromotor fueled by stomach acid can take a bubble-powered ride inside a mouse. These tiny motors, each about one-fifth the width of a human hair, may someday offer a safer and more efficient way to deliver drugs or diagnose tumors.

31 Jan 2015

Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths.

30 Jan 2015

Fujian University of Traditional Chinese Medicine installs MILabs PET-SPECT-CT preclinical imaging system

Fujian University of Traditional Chinese Medicine, in Fuzhou, China has installed a MILabs VECTor/CT system to boost their neurological research with preclinical Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT).

30 Jan 2015

INRS researchers to use new specialized equipment to study environmental equity, male infertility

With the acquisition of new specialized equipment, INRS researchers Philippe Apparicio, Géraldine Delbès, and Maritza Jaramillo and their teams will be able to advance knowledge and train highly qualified people in the fields of environmental equity, reproductive toxicology, and the treatment of infections. They received a total of over $1 million from the Quebec government and the John R. Evans Leaders Fund of the Canadian Foundation for Innovation.

22 Jan 2015

Tübingen researchers develop new way of labeling T-cells

To better understand what happens during immune reactions in the body, researchers at Tübingen University have developed a new way of labeling T-cells, allowing them to track the T-cell movement in mice using non-invasive positron emission technology (PET).

19 Jan 2015

Study: Stem cells derived from human female amnion have anti-inflammatory effects

Stem cells derived from human amnion have for some time been considered promising for cell therapies because of their ease of access, ability to differentiate, and absence of ethical issues.

17 Jan 2015

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

Crown Bioscience, Inc., a leading global drug discovery and development service company, has announced its first European symposium, detailing the use of Translational Platforms including Patient-Derived Xenograft (PDX) models in oncology drug discovery and development. The conference will be held on Wednesday 11th February, at the headquarters of One Nucleus in Cambridge, UK and will welcome experts from renowned pharmaceutical companies and prominent academics working in oncology.

15 Jan 2015

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive licensing deal with PharmAbcine Inc. for the development, manufacturing and marketing of DIG-KT, a bi-specific monoclonal antibody ("mAb") targeting both VEGFR2/KDR and Tie-2 pathways for cancer in the territory of Greater China (including mainland China, Taiwan, Hong Kong and Macau) and Korea.

14 Jan 2015

PF-114 shows promise in therapy-resistant CML, Ph-positive ALL

PF-114, a selective tyrosine kinase inhibitor, is active against native and mutated forms of the BCR–ABL oncogene in Philadelphia chromosome-positive leukaemias, according to preclinical cellular and in vivo results published in Leukemia.

12 Jan 2015

in vivo News and Research

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

Study findings could help scientists better design silicon materials to improve chemotherapy drug delivery

AXT adds TriFoil imaging products to their preclinical imaging portfolio

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

AXT establishes preclinical imaging portfolio with MR solutions product lines

New findings could pave way to develop drug therapies for necrosis-related diseases

New study provides better understanding of how stem cells give rise to tumors

Recipients of The 2015 Protein Society Awards announced

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

Micromotor fueled by stomach acid effectively delivers gold nanoparticles

Synthetic compound shows antibiotic action against MRSA

Fujian University of Traditional Chinese Medicine installs MILabs PET-SPECT-CT preclinical imaging system

INRS researchers to use new specialized equipment to study environmental equity, male infertility

Tübingen researchers develop new way of labeling T-cells

Study: Stem cells derived from human female amnion have anti-inflammatory effects

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

PF-114 shows promise in therapy-resistant CML, Ph-positive ALL

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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