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Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Bevacizumab may enhance the antitumour activity of erlotinib by increasing the intratumoural concentration of erlotinib in some non-small-cell lung cancers expressing high levels of vascular endothelial growth factor, Japanese researchers report.

13 Nov 2014

LaVision BioTec introduce new products for their UltraMicroscope and TriM Scope microscopy products at Neuroscience 2014

LaVision BioTec, developers of advanced microscopy solutions for the life sciences, announce they will introduce new products for their UltraMicroscope and TriM Scope microscopy products at the 2014 annual meeting of the Society for Neuroscience (SfN).

13 Nov 2014

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease.

13 Nov 2014

Researchers create microtube platform to analyze neuron growth

Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury.

12 Nov 2014

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended September 30, 2014.

10 Nov 2014

Scientists may have discovered new way to repair damaged tissue

By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation (early online), appeared to improve blood flow, oxygenation, and nutrition to areas in need.

9 Nov 2014

UCSD researchers describe surprising role of protein in embryonic development

Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced pluripotent stem cell (iPSC) replacements that might address a host of blood disorders.

7 Nov 2014

Light-activated diabetes drug: an interview with Dr David Hodson

We've known about chemicals that can be light-activated for about five to ten years now. They’ve mainly all been applied to neurons and, more specifically, the retina. Nobody has ever really looked at any tissues outside of the nervous system.

5 Nov 2014

CytRx provides overview of clinical development programs, reports 2014 Q3 financial results

CytRx Corporation (CYTR), a biopharmaceutical research and development company specializing in oncology, today reported financial results for the three months ended September 30, 2014, and also provided an overview of recent accomplishments by and upcoming milestones for its clinical development programs.

4 Nov 2014

New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

Researchers develop new technique to create cellular scaffolding for tissue engineering

Researchers at the University of Washington have developed a way to use sound to create cellular scaffolding for tissue engineering, a unique approach that could help overcome one of regenerative medicine's significant obstacles.

31 Oct 2014

Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study.

30 Oct 2014

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, economically viable, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options.

28 Oct 2014

Population Council to present research on novel approaches to HIV prevention at HIV R4P 2014

The Population Council will present new research on novel approaches to HIV, sexually transmitted infections (STIs), and unintended pregnancy prevention at the HIV Research for Prevention Conference, (HIV R4P) in Cape Town, South Africa. HIV R4P, which runs 28–31 October, is the first global scientific meeting dedicated exclusively to research on biomedical HIV prevention.

27 Oct 2014

Crown Bioscience announces U.S. expansion with new translational oncology center

Crown Bioscience, Inc., a leading global drug discovery and development service company, has announced the opening of the Crown Bioscience US Research Center to be located at the David H. Murdock Research Institute (DHMRI), in Kannapolis, N.C. The new center, which will open in the 3rd quarter of 2014, represents significant U.S. market expansion for Crown.

21 Oct 2014

YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

YEDA Research and Development Company Ltd., the technology transfer arm of the Weizmann Institute of Science, Israel, and XL-protein GmbH, Germany, a privately owned biopharmaceutical company, have signed a business collaboration agreement to commercialize a PASylated interferon superagonist -- PAS-YNSα8 -- which has been jointly developed by scientists at the Weizmann Institute and XL-protein.

21 Oct 2014

New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

MILabs BV has launched a complete new preclinical product line at the 2014 Annual European Association of Nuclear Medicine Meeting in Gothenburg, Sweden, October 18-22 (www.eanm.org). It consists of the new 4-series comprising U-SPECT4, U-SPECT4CT, VECTor4 and VECTor4CT incorporating significant improvements over the former PLUS-series. The 4-series carries even further the tradition of MILabs to deliver the best SPECT and PET image resolution available in the market.

20 Oct 2014

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

In a first step toward future human therapies, researchers at The Saban Research Institute of Children's Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue Engineering, Part A.

20 Oct 2014

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy.

17 Oct 2014

Cell transplantation treatment may benefit people with spinal cord injury

Two studies recently published in Cell Transplantation reveal that cell transplantation may be an effective treatment for spinal cord injury (SCI), a major cause of disability and paralysis with no current restorative therapies.

16 Oct 2014

in vivo News and Research

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

LaVision BioTec introduce new products for their UltraMicroscope and TriM Scope microscopy products at Neuroscience 2014

Unique immunochemotherapy approach to treating pancreatic cancer

Researchers create microtube platform to analyze neuron growth

Inovio Pharmaceuticals reports Q3 2014 financial results, provides corporate update

Scientists may have discovered new way to repair damaged tissue

UCSD researchers describe surprising role of protein in embryonic development

Light-activated diabetes drug: an interview with Dr David Hodson

CytRx provides overview of clinical development programs, reports 2014 Q3 financial results

New research sheds light on future efforts to eradicate HIV from the body in human patients

Researchers develop new technique to create cellular scaffolding for tissue engineering

Insufficient Th1 polarisation blocks RCC vaccine efficacy

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

Population Council to present research on novel approaches to HIV prevention at HIV R4P 2014

Crown Bioscience announces U.S. expansion with new translational oncology center

YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

Esophageal tissue can be grown in vivo from human and mouse cells, say researchers

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Cell transplantation treatment may benefit people with spinal cord injury

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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