CakeStand™ vacuum tray dryer: Precision drying for delicate pharmaceutical processes

Although the pharmaceutical industry has developed more sophisticated drying techniques, vacuum tray dryer technology is still a vital tool for processes and products that are brittle or delicate when subjected to mechanical forces.

The CakeStandTM vacuum tray dryer technology uses direct heating shelves and a completely sealed vacuum chamber for the best drying conditions and consistency.

PSL containment isolators, clean rooms, and downflow booths are among the environments in which PSL tray dryers can be used. CakeStandTM has also been designed with several features that enhance user-friendliness and product security.

Download the Brochure for More Information

Features and benefits

An all-in-one solution

PSL's CakeStandTM Tray Dryers combine direct heated shelves with a vacuum chamber to achieve validated uniform heating of +/-1 °C across the shelves, essential for producing consistently high-quality end products. This feature helps users meet their most demanding batch-processing requirements.

CakeStand™ vacuum tray dryer: Precision drying for delicate pharmaceutical processes

Image Credit: Powder Systems

cGMP design

The CakestandTM Tray Dryers have features that adhere to cGMP and were created with the pharmaceutical industry in mind.

  • Suspended shelves to prevent the formation of difficult-to-clean product “pockets” or product traps.
  • Completely metallic internal product contact parts for simple cleaning validation, featuring regulated edge and corner radiuses and surface finishes.
  • Use the front flat metallic door for easy cleanup in a clean room or isolation environment.
  • Utility connection points positioned appropriately to be kept out of the process room are installed in a through-wall layout for easy maintenance.

Download the Brochure for More Information

Batch reproducibility and data recording

The CakestandTM Tray Dryers are available alone or with a software and automation package for a client or third-party integration.

Drug producers can increase the speed and flexibility of their manufacturing processes by pre-designing and pre-loading software process recipes with the pertinent process parameters appropriate for their unique production requirements using the PSL Automation Platform.

PSL can comply with major international standards and regulations for software automation, including GAMP5 (Good Automated Manufacturing Practice, version 5 by ISPE) and 21 CFR Part 11, established by the US FDA for electronic records and signatures.

CakeStand™ vacuum tray dryer: Precision drying for delicate pharmaceutical processes

Image Credit: Powder Systems

Be containment-ready

The loading and unloading of the product trays are still done manually, even though a vacuum tray dryer does not require physical operator intervention during the drying phase. These procedures must be followed if the product is strong or toxic, as is frequently the case in pharmaceutical applications involving API or HPAPI.

CakeStand™ vacuum tray dryer: Precision drying for delicate pharmaceutical processes

Image Credit: Powder Systems

Depending on the product classification, several containment strategies may be used, and the CakestandTM Tray Dryers are adaptable enough to work with the majority of them:

  • As stand-alone within the downflow booth.
  • Incorporated into a downflow booth's rear wall to reduce the space taken up in the important air-swept area.
  • Tray dryer size restrictions may apply when integrated into the back wall of an isolator due to the ergonomic challenges of working through Gloves. PSL’s expertise in designing containment isolators will guide users through these considerations.

Download the Brochure for More Information

Technical overview

Applications and options

Shelf and Tray Configurations. Source: Powder Systems

. . . . . .
Typical number of Shelves 2 4 / 6 4 / 6 4 / 6 / 8 6 / 12
Useful Shelf Area (min / max) (m²) 0.2 0.25 / 0.375 0.8 / 1.2 3.1 / 4.6 / 6.2 6.8 / 13.60
Chamber Volume 40 L 85 L 160 L 1000 L 2500 L
Downflow Booth Integration Yes
PSL GloveBox Integration Yes No

Other Equipment by this Supplier

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.