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Researchers discover treatment for severe auto inflammatory syndrome

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of--and a treatment for--a previously unknown severe auto inflam-matory syndrome affecting an 18-year-old girl since infancy.

4 Aug 2020

Trial to examine if new psychological therapy can help tackle problem drinking

A psychological therapy found to be effective in helping people achieve and maintain weight loss is being trialled to see if it can support patients with chronic liver disease to stop drinking.

4 Aug 2020

Researcher is exploring safer and more effective treatment for leukemia

A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences.

4 Aug 2020

Researchers use zeolite nanocrystals to deliver oxygen to brain tumors

Glioblastoma, the most widespread and lethal primary brain tumor in adults, is notoriously difficult to treat due to the surrounding lack of oxygen essential to the effectiveness of current treatment.

4 Aug 2020

Heart cell treatment can benefit patients, shows study

More than three years after a clinical trial was prematurely ended for failing to show progress in healing heart attack scars, a prominent peer-reviewed journal is publishing some surprising results showing that the heart cell treatment does benefit patients.

4 Aug 2020

Normal DNA repair process can lead to mutations in cancer

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer.

4 Aug 2020

Researchers achieve bleeding-free anti-coagulation with synthetic inhibitor

Patients who suffer from thrombosis, pulmonary embolism or stroke are usually put on drugs that help their blood flow more smoothly through their body.

4 Aug 2020

Early blood test could detect birth asphyxia

An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy.

4 Aug 2020

AI-enabled ECG provides a rapid and effective method to screen heart failure

When people seek emergency care for shortness of breath, a routine electrocardiogram (ECG or EKG) enhanced by artificial intelligence (AI) is better than standard blood tests at determining if the cause is heart failure, according to new research published today in Circulation: Arrhythmia and Electrophysiology, an American Heart Association journal.

4 Aug 2020

Research reveals potential early indicator of Fragile X-associated tremor/ataxia syndrome

A new paper in the journal NeuroImage: Clinical from researchers at the University of Kansas reveals a possible early indicator of Fragile X-associated tremor/ataxia syndrome, or FXTAS.

4 Aug 2020

Despite COVID-19 pressures, hospitals are maintaining emergency cardiac services in majority of cases

The death rate for patients who experienced what is normally a lower-risk heart attack rose sharply during the peak of the COVID-19 pandemic in England, according to an analysis of NHS data.

4 Aug 2020

Researchers initiate multiple studies to identify coronavirus-related heart problems

COVID-19 is shown to impact the heart and, in some cases, have long-lasting cardiac effects. To discover the extent to which COVID-19 affects the heart, cardiologists and researchers with the University of Miami Miller School of Medicine have begun multiple studies.

4 Aug 2020

Broad range of therapeutics are being evaluated for Parkinson's disease

A review of currently registered clinical trials of agents targeting Parkinson's disease (PD) reveals that there is a broad pipeline of both symptomatic and potentially disease-modifying therapies currently being evaluated.

4 Aug 2020

ALKBH5 enzyme shows promising target for cancer immunotherapy

Cancer immunotherapy - a treatment that better enables a patient's own immune system to attack tumors - has shown great potential against some cancers. Yet immunotherapy doesn't work against all tumor types, and many patients who initially respond later develop resistance and relapse.

4 Aug 2020

Targeting LDL cholesterol to reduce heart disease risk now questioned

For many years, health experts have warned that high levels of bad cholesterol or low-density lipoprotein (LDL) are critical drivers for the development of cardiovascular disease. Now, a new study claims that decades of research have failed to show benefit of targeting the bad cholesterol to reduce the risk of cardiovascular disease.

4 Aug 2020

How COVID-19 lockdown affected the heart

A new study published on the preprint server medRxiv in August 2020 shows that heart rate variability assessments, used to evaluate the health of the heart and blood vessels, are useful in identifying changes in health and well being throughout lockdown related to COVID-19.

4 Aug 2020

Artificial intelligence can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

3 Aug 2020

AGA white paper provides a roadmap for colorectal cancer screening

Fewer people would die of colorectal cancer if health care providers adopted a new model of screening that combines better risk assessment, more options for noninvasive testing and more targeted referrals for colonoscopy.

3 Aug 2020

Insights into prevalence, incidence, and impact of COPD in older adults

"Recognizing and Treating COPD in Older Adults," the latest issue of the What's Hot newsletter from The Gerontological Society of America, addresses what is known about the prevalence, incidence, and impact of chronic obstructive pulmonary disease (COPD) in older adults.

3 Aug 2020

Study reveals impact of TP53 gene mutations on MDS severity

Considered the "guardian of the genome," TP53 is the most commonly mutated gene in cancer. TP53's normal function is to detect DNA damage and prevent cells from passing this damage on to daughter cells.

3 Aug 2020