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Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

26 Jul 2024

Anxiety’s Long-Term Impact on Dementia Development

The longitudinal relationship between chronic, resolved, and new onset anxiety and the risk of all-cause dementia (Progressive cognitive decline affecting memory and thinking).

26 Jul 2024

Machine learning models predict disability progression in multiple sclerosis

Machine learning models can reliably inform clinicians about the disability progression of multiple sclerosis, according to a new study published this week in the open-access journal PLOS Digital Health by Edward De Brouwer of KU Leuven, Belgium, and colleagues.

25 Jul 2024

Cordyceps sinensis shown to alleviate idiopathic pulmonary fibrosis in mice

A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.

25 Jul 2024

Medicaid policies boost oncology clinical trial enrollment for Black and Hispanic patients

Two Medicaid policies can interact to increase oncology clinical trial enrollment among Black and Hispanic patients, according to a new study by investigators at Weill Cornell Medicine, the University of Pennsylvania, and Medidata AI.

25 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

New review highlights advances in diabetes research and treatment

A new paper surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

25 Jul 2024

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Researchers created a detailed transcriptomic atlas of six brain regions, revealing cell-type-specific and region-specific vulnerabilities in Alzheimer's disease and highlighting astrocyte genes linked to cognitive resilience.

25 Jul 2024

UQ opens new facility for personalized mRNA cancer vaccine development

A new facility at The University of Queensland is set to provide Australian researchers with cancer vaccines tailored to individual patients.

25 Jul 2024

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

UK initiative aims to transform MND research through health data collaboration

MND is a devastating disease affecting the motor neurones in the brain and spinal cord, leading to progressive muscle weakness and paralysis.

25 Jul 2024

Can cutting back on extra virgin olive oil make your heart healthier?

Two levels of extra virgin olive oil intake in a plant-based diet both reduce LDL cholesterol, with lower intake showing a more significant effect.

25 Jul 2024

Research reveals Medicare's inadequate payments for lifesaving stroke procedures

Despite thrombectomy's high success rate in saving the lives of stroke patients, Medicare is paying lower rates over time for the procedure, according to research presented today at the Society of NeuroInterventional Surgery's (SNIS) 21st Annual Meeting.

25 Jul 2024

Posterior foraminotomy shows comparable results to anterior discectomy for cervical radiculopathy

For patients with cervical radiculopathy, posterior foraminotomy provides outcomes comparable to those of the more commonly performed anterior cervical discectomy, reports a randomized clinical trial in The Journal of Bone & Joint Surgery.

25 Jul 2024

Noninvasive home test significantly cuts colorectal cancer mortality

A noninvasive colorectal cancer screening test that can be done at home could reduce the risk of colorectal cancer death by 33%, according to a new study published in JAMA Network Open.

25 Jul 2024

Electrical currents could supercharge cancer-killing immune cells, study finds

Scientists have discovered that electrical currents may make Natural Killer (NK) cells – our very own cancer-killing immune cells – even better killers, which could have significant implications for treating some cancers.

25 Jul 2024

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

In a rigorous medical records study covering tens of thousands of patients, Johns Hopkins Medicine researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego -; a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research-;live, human muscle cells grown on scaffolds fixed on tiny chips-;lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory.

25 Jul 2024

Fecal microbiota transplants can boost the effectiveness of immunotherapy in gastrointestinal cancers

Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers.

25 Jul 2024