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Study compares T-cell signaling patterns in two different CAR designs

CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded to other treatments. But until now, the underlying biological pathways enabling anti-cancer responses have not been thoroughly examined.

21 Aug 2018

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you - or your dog?

21 Aug 2018

Blood test could identify bladder cancer patients who may not benefit from immunotherapy

Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test, according to researchers at Brighton and Sussex Medical School.

21 Aug 2018

Researchers receive multi-million-dollar grant to expand kidney research

Researchers at University of California San Diego School of Medicine and the University of Alabama at Birmingham School of Medicine have received renewed grant funding from the National Institute of Diabetes and Digestive and Kidney Diseases to expand research into the areas of acute kidney failure and acute kidney injuries.

21 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Depressed patients treated with nerve stimulation experience improvements in quality of life

People with depression who are treated with nerve stimulation experience significant improvements in quality of life, even when their depression symptoms don't completely subside, according to results of a national study led by researchers at Washington University School of Medicine in St. Louis.

21 Aug 2018

Researchers explore use of antipsychotic medications in older adults following heart surgery

Delirium is the medical term for an abrupt, rapid change in mental function that goes well beyond the typical forgetfulness of aging.

21 Aug 2018

Largest brain imaging study uncovers factors that accelerate brain aging

In the largest known brain imaging study, scientists from Amen Clinics, Google, John's Hopkins University, University of California, Los Angeles and the University of California, San Francisco evaluated 62,454 brain SPECT scans of more than 30,000 individuals from 9 months old to 105 years of age to investigate factors that accelerate brain aging. SPECT tomography evaluates regional cerebral blood flow in the brain that is reduced in various disorders.

21 Aug 2018

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Researchers at Lund University in Sweden have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease.

21 Aug 2018

Ultrasound methods could improve early detection of diseases in blood vessels, shows study

Ultrasound conducted before a patient develops symptoms could improve early detection of diseases in blood vessels, research led by the University of Leicester has shown.

21 Aug 2018

Intellectual deterioration related to work status in patients with schizophrenia

Osaka University-led Japanese researchers clarified that intellectual deterioration (IQ decline) was related to work status in patients with schizophrenia.

21 Aug 2018

Emerging field of diabetology could address growing crisis in health care

The emerging field of diabetology--a sub-specialty of endocrinology focused on the treatment of people with diabetes--is intended to address an emerging crisis in health care: Nearly one-third of Americans has a type 2 diabetes diagnosis or has prediabetes.

21 Aug 2018

Scientists report novel gene therapy that halts vision loss in canine model of blinding disease

Scientists funded by the National Eye Institute report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP). The strategy could one day be used to slow or prevent vision loss in people with the disease. NEI is part of the National Institutes of Health.

21 Aug 2018

Simple leg exercises may prevent heart, blood vessels disease caused by sedentary lifestyle

A sedentary lifestyle can cause an impairment of the transport of blood around the body, which increases the risk of disease in the heart and blood vessels.

21 Aug 2018

Research provides drug developers with much needed insight into serotonin receptor

Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface of cells. Far from it. Many approved drugs also bind to serotonin receptors.

21 Aug 2018

Temple University Hospital becomes the first in U.S. to perform BLVR using Zephyr valve

Temple University Hospital has become the first U.S. center to perform bronchoscopic lung volume reduction using implantation of the Zephyr Endobronchial Valve to treat severe emphysema following U.S. FDA approval.

21 Aug 2018

Experts examine stool protein biomarkers that indicate inflammatory bowel disease

University of Houston researcher Chandra Mohan is set to make a breakthrough in predicting and monitoring inflammatory bowel disease.

21 Aug 2018

Scientists find two molecules that may combat cancer and chronic infections

To fight viral infections, your immune system calls on CD8 T cells to kill the infected cells. The CD8 T cells can also be used in immunotherapy approaches to kill cancer cells, including the CAR T cell therapy currently attracting broad public attention.

21 Aug 2018

A form of vitamin B3 shows potential to prevent acute kidney injury

Acute kidney injury, an often fatal condition without a specific treatment, affects up to 10 percent of all hospitalized adults in the United States and 30-40 percent in low-income countries.

21 Aug 2018

AADE honors six educators for achievements in diabetes education

Six diabetes educators were honored for their achievements in the field of diabetes education and their dedication to the American Association of Diabetes Educators during its annual conference.

21 Aug 2018

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Medical Condition News

Study compares T-cell signaling patterns in two different CAR designs

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

Blood test could identify bladder cancer patients who may not benefit from immunotherapy

Researchers receive multi-million-dollar grant to expand kidney research

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Depressed patients treated with nerve stimulation experience improvements in quality of life

Researchers explore use of antipsychotic medications in older adults following heart surgery

Largest brain imaging study uncovers factors that accelerate brain aging

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Ultrasound methods could improve early detection of diseases in blood vessels, shows study

Intellectual deterioration related to work status in patients with schizophrenia

Emerging field of diabetology could address growing crisis in health care

Scientists report novel gene therapy that halts vision loss in canine model of blinding disease

Simple leg exercises may prevent heart, blood vessels disease caused by sedentary lifestyle

Research provides drug developers with much needed insight into serotonin receptor

Temple University Hospital becomes the first in U.S. to perform BLVR using Zephyr valve

Experts examine stool protein biomarkers that indicate inflammatory bowel disease

Scientists find two molecules that may combat cancer and chronic infections

A form of vitamin B3 shows potential to prevent acute kidney injury

AADE honors six educators for achievements in diabetes education

Understanding How Antibodies Shape the Gut Microbiome

Exosomes: Are They All Alike and Why Does it Matter?

High Throughput Biophysical Screening for Development and Formulation of Biologics

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