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Expert work group examines and redefines “clinical meaningfulness” in Alzheimer’s

As the Alzheimer's disease scientific community, patients, and families seek to understand the results of clinical trials of new Alzheimer's treatments, the Alzheimer's Association convened an expert work group to discuss an important and timely issue: the "clinical meaningfulness" of results from these studies.

7 Feb 2023

In the wake of Chantix's recall, Varenicline use for nicotine dependence dropped by 75%

The recent JAMA Network Open study evaluated how the Chantix recall influenced prescribing varenicline and other nicotine dependency medications. For this cross-sectional study, a large US-based national cohort was used. All relevant data between January 1, 2021, and June 30, 2022, was obtained from the national pharmacy benefit database.

7 Feb 2023

Men with low sexual desire might benefit from kisspeptin

A new study in the journal JAMA Network Open aimed to analyze the mechanistic and clinical effects of the administration of kisspeptin in men with HSDD.

7 Feb 2023

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is an important risk factor for type 2 diabetes and cardiovascular diseases.

7 Feb 2023

Study finds distinct differences in how the brain releases dopamine in patients with alcohol use disorder

Dopamine is a neurotransmitter that's made in the brain and acts as a chemical messenger, communicating between nerve cells in the brain and the rest of the body.

7 Feb 2023

Study reveals some of the fundamental biology of p97 protein in neurodegenerative disease

The p97 protein is one of your body's best garbage disposers. It floats around in your cells looking for signals that a protein is past its shelf life and needs to be trashed.

7 Feb 2023

Scientists discover new way to reduce progression of diabetic kidney disease

A new way to reduce progression of diabetic kidney disease, affecting 40% of people with diabetes, has been discovered by scientists.

7 Feb 2023

Do individuals with long COVID ever recover fully?

Researchers investigate the sociodemographic factors that contribute to the remission of long COVID.

7 Feb 2023

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

Pancreatic cancer diagnoses are increasing more rapidly than any other cancer type while remaining one of the most deadly cancers.

7 Feb 2023

New scientific statement proposes ideal foundational requirements for stroke centers

A new American Heart Association scientific statement provides guidance on staffing, leadership and resource requirements for hospital stroke centers to reduce variability and improve quality of care at stroke centers across the U.S.

7 Feb 2023

IU School of Medicine researchers secure grant to study new treatment method for traumatic brain injury

Indiana University School of Medicine and National Intrepid Center of Excellence (NICoE) researchers are collaborating to study a new treatment method for traumatic brain injury (TBI) thanks to a grant from the United States Department of Defense, Congressionally Directed Medical Research Programs (CDMRP).

7 Feb 2023

Understanding the relationship between SARS-CoV-2 infection and periodontitis

In a recent review published in the journal International Journal of Molecular Sciences, researchers reviewed existing data on the association between periodontitis and coronavirus disease 2019 (COVID-19).

7 Feb 2023

Does alcohol consumption increase dementia risk?

A recent study examines the association between alcohol use and dementia risk, as well as changes in the drinking pattern.

7 Feb 2023

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Researchers investigate the obstetric and neonatal outcomes in unvaccinated pregnant females infected with the SARS-CoV-2.

7 Feb 2023

Study reports two cases of ocular MPox in HIV-infected patients

Researchers review the symptoms, diagnosis, and treatment of ocular Mpox syndrome in men living with HIV infection.

7 Feb 2023

Novel type of combination therapy shows potential in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive form of cancer that originates in the bone marrow, rapidly spreads to the blood and can quickly cause death if not treated promptly.

7 Feb 2023

People who regularly drink coffee have significantly lower blood pressure

Drinking coffee helps maintain low blood pressure. People who drink two or three cups of coffee a day have lower blood pressure than those who drink just one cup or none at all.

7 Feb 2023

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

The immunosuppressive drug methotrexate (MTX) can be linked to an elevated risk of three types of skin cancer, a new study by University of Gothenburg researchers shows.

7 Feb 2023

USC researchers identify two promising avenues for developing new ALS treatments

Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years.

7 Feb 2023

Early treatment of diabetes-related eye disease does not improve visual acuity

While early treatment of diabetes-related eye disease slowed progression to severe disease, it did not improve visual acuity compared with treating more severe disease once it developed, according to a clinical study from the DRCR Retina Network.

7 Feb 2023

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Medical Condition News

Expert work group examines and redefines “clinical meaningfulness” in Alzheimer’s

In the wake of Chantix's recall, Varenicline use for nicotine dependence dropped by 75%

Men with low sexual desire might benefit from kisspeptin

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Study finds distinct differences in how the brain releases dopamine in patients with alcohol use disorder

Study reveals some of the fundamental biology of p97 protein in neurodegenerative disease

Scientists discover new way to reduce progression of diabetic kidney disease

Do individuals with long COVID ever recover fully?

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

New scientific statement proposes ideal foundational requirements for stroke centers

IU School of Medicine researchers secure grant to study new treatment method for traumatic brain injury

Understanding the relationship between SARS-CoV-2 infection and periodontitis

Does alcohol consumption increase dementia risk?

Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant

Study reports two cases of ocular MPox in HIV-infected patients

Novel type of combination therapy shows potential in acute myeloid leukemia

People who regularly drink coffee have significantly lower blood pressure

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

USC researchers identify two promising avenues for developing new ALS treatments

Early treatment of diabetes-related eye disease does not improve visual acuity

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

Importance of Global Pandemic Predictions for Future Outbreaks; How prepared are we?

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