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New CRISPR technique boosts mitochondrial function to treat heart failure

After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart failure as a result ⎯ a condition that impacts 6.8 million Americans and carries a high lifetime risk with 1 in 4 adults in the U.S. expected to develop the condition during their lifetime.

9 Mar 2026

$Biomimetic platform enhances CAR T therapy for relapsed and refractory leukemia$

Biomimetic platform enhances CAR T therapy for relapsed and refractory leukemia

Chimeric antigen receptor T (CAR T) cell therapy represents a milestone in leukemia treatment. CAR T works by genetically engineering a chimeric antigen receptor on the surface of the patient's T cells to target specific antigens on leukemia cells, with the goal of identifying and eliminating them.

9 Mar 2026

Women face higher liver fibrosis risk from cardiometabolic factors than men

Women with certain cardiometabolic risk factors, including type 2 diabetes and high waist circumference, face a greater increase in risk for liver fibrosis than men with the same risk factors.

9 Mar 2026

Recreational drugs significantly increase the risk of stroke

The recreational drugs cannabis, cocaine and amphetamines significantly increase the risk of stroke – including among younger users – Cambridge researchers have concluded after analyzing data from more than 100 million people.

9 Mar 2026

Adult stimulant prescriptions more than doubled since the start of the pandemic

New prescriptions for stimulants among adults, largely to treat ADHD, more than doubled since the start of the COVID-19 pandemic, especially in younger adults, found new research published in CMAJ.

9 Mar 2026

Spiritual care should be routine for patients with neurological diseases

People living with neurological diseases such as Parkinson's disease, dementia and epilepsy face not only physical decline, but also profound questions about identity, purpose, and meaning.

9 Mar 2026

Most weight lost on GLP-1 drugs returns within a year after stopping

The cessation of GLP-1RAs is linked to a 60% weight regain within a year, emphasizing the importance of tailored strategies for effective long-term weight loss.

9 Mar 2026

FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy

Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy.

9 Mar 2026

Unmasking the hyperactive circuitry of early Alzheimer’s

Neuroscientists at King's College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer's disease.

9 Mar 2026

Identifying common genetic markers for multiple sclerosis

A new study published in Neurology and led by Queen Mary University of London, has revealed that people of South Asian, African and European ancestry share many of the same genetic risk factors for multiple sclerosis (MS).

9 Mar 2026

Yale study identifies parent stress as an obesity risk factor

In recent years, rates of childhood obesity have been rising, with the U.S. Centers for Disease Control estimating in 2024 that approximately one in five children and adolescents met the clinical definition of obese.

9 Mar 2026

Could GLP-1 drugs help curb addiction? Large veteran study points to potential benefit

A large cohort study of more than 600,000 US veterans with type 2 diabetes found that initiating GLP-1 receptor agonists was associated with lower risks of developing substance use disorders compared with SGLT-2 inhibitors. Among veterans with existing substance use disorders, GLP-1 receptor agonist use was also linked to fewer overdose events, hospitalizations, and suicide-related outcomes.

8 Mar 2026

How somatic mutations shape disease and reveal new drug targets

Researchers reviewed how somatic mutations accumulate in normal and diseased tissues, showing that natural selection can expand clones that influence disease risk, tissue adaptation, or cellular resilience. The study proposes somatic genomics as a powerful strategy to uncover disease mechanisms and identify new therapeutic targets across multiple conditions.

8 Mar 2026

Report highlights gaps in cancer care access for tribal citizens

The University of Oklahoma's Native Nations Center for Tribal Policy Research recently released a new Sovereign Report titled "Purchased/Referred Care and Cancer: Overview and Options for Tribal Consideration."

6 Mar 2026

Med14 protein drives GLP-1 benefits in pancreatic beta cells

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health.

6 Mar 2026

Case report describes treatment of rare calcified solid pseudopapillary pancreatic tumor

A new case report was published in Volume 13 of Oncoscienceon February 7, 2026, titled "Massive calcified solid pseudopapillary neoplasm of the pancreatic head."

6 Mar 2026

Modified psilocybin compounds may treat brain disorders with fewer hallucinations

Psilocybin - the psychoactive compound in "magic mushrooms" - is gaining scientific attention for its potential in treating neuropsychiatric conditions including depression, anxiety, substance use disorders and certain neurodegenerative diseases.

6 Mar 2026

Tubulin prevents toxic protein clumps linked to neurodegeneration

Researchers at Baylor College of Medicine have discovered a potential new strategy to fight back against Alzheimer's and Parkinson's diseases, conditions that are linked to the toxic accumulation of Tau and alpha synuclein protein clumps in the brain.

6 Mar 2026

Wnt signaling in fibroblasts drives gastric cancer metastasis to the liver

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs.

6 Mar 2026

Virtual immunostaining method improves detection of vascular invasion in thyroid cancer

In a groundbreaking study published in BME Frontiers, researchers from the University of California, Los Angeles (UCLA), in collaboration with international partners, have developed a deep learning-based virtual multiplexed immunostaining (mIHC) method.

6 Mar 2026