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Engineered lettuce may turn injectable GLP-1 therapies into oral pills

Few drugs have entered mainstream awareness as quickly or as dramatically as glucagon-like peptide-1, or GLP-1 receptor agonists. Initially approved by the FDA for the treatment of type 2 diabetes, they have since also transformed the therapeutic landscape of obesity and weight management.

6 Mar 2026

Surgical robot can help safely remove the caudate lobe

Resection of tumors in the caudate lobe (a deep, hard-to-reach part of the liver) is recognized as one of the most technically challenging procedures in hepatic surgery due to its unique anatomical position and complex vascular relationships.

6 Mar 2026

Scientists identify common molecular program across multiple brain tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program.

6 Mar 2026

Single dose of CAR-astrocyte therapy halves amyloid levels in mice brains

The new generation of Alzheimer's disease drugs - the first proven to change the course of the disease - typically extend independent living for patients by 10 months.

6 Mar 2026

Adults' exposure to diverse microbes may worsen allergic conditions

The "hygiene hypothesis" suggests exposure to diverse types of microbes may protect against developing diseases caused by allergens, but a new Cornell University study in mice reveals that adults' exposure to diverse microbes and allergens may in fact worsen certain allergic conditions.

6 Mar 2026

New report shows primary care readiness for digital cognitive assessment tools

A new Gerontological Society of America (GSA) report summarizes survey findings on the readiness of the primary care workforce to adopt digital cognitive assessments (DCAs) for use in the diagnostic process for cognitive impairment and dementia.

6 Mar 2026

Weekend lie-ins may boost insulin sensitivity, but too much may backfire

This study explores the relationship between sleep patterns and insulin sensitivity, emphasizing the impact of weekday sleep and weekend catch-up on metabolism.

6 Mar 2026

Higher pollen levels linked to lower exam scores

New research links pollen exposure to lower exam scores in Finnish students, highlighting its potential impact on academic performance and future opportunities.

6 Mar 2026

MSK uncovers how interacting mutations shield breast cancer

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have made an important discovery about how genetic mutations in breast cancer patients can interact and drive resistance to certain drugs called CDK4/6 inhibitors. This finding, published in Nature, suggests a new strategy for predicting and preventing resistance to specific therapies based on the tumor's genetic profile.

6 Mar 2026

BCAT2 enzyme identified as a target for diabetic foot recovery

Diabetic macrovascular complications are the main cause of death and disability in diabetes patients, of which vascular calcification is one of the key pathological mechanisms. Calcification in atherosclerotic plaque can cause stiffness and decreased compliance of the vascular wall, and induce atherosclerotic plaque rupture, which increases the risk of acute cardiovascular events.

6 Mar 2026

A review of methionine dependency in modern cancer therapy

Methionine restriction (MR) has shown significant promise in cancer therapy because it targets the unique methionine dependency of many tumors. However, despite extensive research on MR, a clear synthesis of preclinical findings and their translation into clinical settings is lacking. This review aims to address this gap by consolidating existing evidence, identifying challenges, and highlighting opportunities for advancing MR as a viable cancer treatment strategy.

6 Mar 2026

A novel approach to improving survival in treatment-resistant cancers

Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as a potential "switch" that can modulate a type of cancer cell death known as immunogenic cell death (ICD).

6 Mar 2026

Trial aims to improve family communication about inherited colorectal cancer risk

In time for Colorectal Cancer Awareness Month in March, the Alliance for Clinical Trials in Oncology has launched a new clinical study aimed at helping improve how patients with colorectal cancer share information about the genetic risks to their family members.

5 Mar 2026

Virtual mental health visits show little impact on rural care access

During the COVID-19 pandemic, mental health specialists started using telemedicine much more frequently.

5 Mar 2026

Dual targeting strategy may improve treatment for resistant lung cancers

Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) support the potential of new therapies that could improve clinical outcomes for patients with squamous and adenocarcinoma non-small cell lung cancers (NSCLC) that don't respond to immunotherapy.

5 Mar 2026

Drug combination shows greater weight loss while preserving muscle mass

A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, such as skeletal muscle and connective tissue.

5 Mar 2026

Combination therapy can reduce harmful effects of senescent cells in diabetic kidney disease

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells – also known as "zombie cells" – in diabetic kidney disease.

5 Mar 2026

Machine learning detects early brain changes linked to Alzheimer's disease

Worcester Polytechnic Institute (WPI) researchers have used a form of artificial intelligence (AI) to analyze anatomical changes in the brain and predict Alzheimer's disease with nearly 93% accuracy.

5 Mar 2026

Single injection may help the heart heal after heart attack

For people who have survived a heart attack, the notion of one shot in the arm to help the heart heal, for weeks after, may seem far‑fetched. But thanks to a team of researchers, including a Texas A&M University professor, that's exactly what could happen.

5 Mar 2026

Researchers propose that Parkinson’s disease may start in the gut, not the brain

A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.

5 Mar 2026