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Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma

The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into adrenal tissue or sympathetic ganglia take a wrong turn, and a child is born harboring a malignancy that may not declare itself for months.

7 Apr 2026

New ruthenium-based active agent enables cancer treatment in oxygen-depleted tumors

Most tumors grow so rapidly that vascular growth cannot keep up, and oxygen-depleted areas form within them. A new active agent could make it possible to treat them with photodynamic therapy.

7 Apr 2026

Dual perspective AI model achieves high accuracy in early lung cancer diagnosis

Lung cancer remains the leading cause of cancer-related deaths worldwide, accounting for nearly one in five cancer deaths - around 1.8 million lives lost each year.

7 Apr 2026

New blood biomarker improves cancer risk detection in people with Lynch Syndrome

Researchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can help identify and characterize asymptomatic people with Lynch Syndrome (LS) who are more susceptible to developing cancer based on early immune detection signatures, allowing clinicians to stratify patients based on their personal risk level.

6 Apr 2026

New technique can simultaneously treat lung cancer and muscle-wasting condition

Researchers at Oregon State University have developed a technique for simultaneously treating lung cancer and a serious muscle-wasting condition that often accompanies it.

6 Apr 2026

New 3D printing method delivers cancer drugs directly to tumors

University of Mississippi research offers hope that cancer drug therapies packaged in 3D-printed carriers could deliver medication directly to tumors while reducing many of the side effects that cancer patients endure.

6 Apr 2026

New compounds reduce inflammation without weakening immune defense

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

6 Apr 2026

Expanded Medicaid improved access to buprenorphine for opioid use disorder

Medicaid insurance expansions between 2017 and 2023 sharply increased access to medication treatment for opioid use disorder in a period when fatal overdoses continued to climb, according to Rutgers Health researchers.

6 Apr 2026

New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

Scientists create large library of mitochondrial DNA mutant models

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

6 Apr 2026

New guidelines aim to improve concussion care for first responders

Management of sports-related concussions has come a long way in the past 25 years: Once considered a minor problem involving minimal time out of the game, a severe knock to the head is now assessed as a potential traumatic brain injury and, if confirmed, requires a structured recovery and an average wait of 13 days before play resumes.

6 Apr 2026

Study shows how blind people map surroundings using sound

Some blind people use returning echoes from their own mouth clicks to perceive external surroundings, or echolocation.

6 Apr 2026

New target identified to overcome resistance in neuroendocrine tumors

Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells.

6 Apr 2026

Prickly pear may pack a surprising punch against metabolic syndrome

This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made.

6 Apr 2026

Study shows masculine depression is not just a male mental health pattern

Researchers found that depressed inpatients with high masculine depression scores had a substantially greater acute mental health burden across multiple symptom domains, even after accounting for overall depression severity. The paper also found this pattern was not specific to men, supporting “masculine depression” as a descriptive, sex-independent behavioral profile rather than a male-only condition.

6 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026