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Study reveals a disease-relevant role for tanycytes in neurodegeneration

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

5 Mar 2026

Distinct spatial tumor–immune ecosystems predict lung cancer treatment response

Researchers at Moffitt Cancer Center have identified distinct spatial tumor–immune ecosystems that predict whether patients with advanced non–small cell lung cancer will benefit from immunotherapy.

5 Mar 2026

New AstroID database integrates clinical and genetic data for large-scale cancer studies

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data - including laboratory results, genetic sequencing and imaging data - in one setting.

5 Mar 2026

Scientists call for integration of physical activity into psychiatric care

People with mental illnesses such as schizophrenia, depression or bipolar disorder die on average ten to 20 years earlier than the general population.

5 Mar 2026

Virtual reality system supports social skills training for people with autism

Researchers at TU Graz are using virtual reality and large language models to support people with autism spectrum disorder in training social skills.

5 Mar 2026

Copper metabolism identified as a new therapeutic target for inflammatory osteolysis

Inflammatory osteolysis is a condition involving progressive bone tissue destruction and is observed in many well-known skeletal disorders, including rheumatoid arthritis, osteoporosis, and chronic apical periodontitis.

5 Mar 2026

High use of anticholinergic drugs linked to increased cardiovascular disease risk

People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease.

5 Mar 2026

Detecting major neurological disorders via saliva

A team of Korean researchers has, for the first time in the world, developed a technology capable of enabling early diagnosis of major neurological disorders, including epilepsy, Parkinson's disease, and schizophrenia, using only a small amount of saliva.

5 Mar 2026

Tracking physiological stress during prolonged virtual soccer

Extended esports play can lead to mental fatigue, resulting in slower and less precise decision-making (diminished executive control) and a variety of physiological responses indicative of impaired sensorimotor or cognitive function.

5 Mar 2026

Using microwave frying to create heart-healthy production methods

Fried foods are popular with consumers, but their high fat content can contribute to health challenges like obesity and hypertension. If the food industry can offer lower-fat options of similar quality, people can more easily make health-conscious food choices.

5 Mar 2026

Youth football accounts for nearly one in five sports-related brain injuries

Youth football accounts for the largest share of sports‑related traumatic brain injuries (TBIs) in children and young adults, nearly one in every five TBIs, according to a preliminary study released March 4, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

5 Mar 2026

Researchers find novel path to treat Rett syndrome

A team of researchers at Texas Children's Duncan Neurological Research Institute (NRI) and Baylor College of Medicine report in Science Translational Medicine a potential new approach to treat Rett syndrome – offering early promise for a rare neurodevelopmental disorder that currently has no cure.

5 Mar 2026

As ICE moved in, Minnesotans set up a shadow medical system. It’s a lesson for other cities.

Gabi has big brown eyes, pigtails, and a genetic condition that makes her bones brittle. They fracture easily, leaving the 2-year-old in such pain that her mother quit her job cleaning offices to stay home and cradle her in the one-bedroom apartment they share with six relatives.

5 Mar 2026

Wearable sensors as a tool for MS monitoring

Wearable sensors may help identify people with multiple sclerosis (MS) who are more likely to have worsening disability and loss of brain volume, according to a study published on March 4th, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

4 Mar 2026

Novel gene regulation therapy passes key clinical milestone

Groundbreaking Phase 1/2a clinical trials co-led by Linda Laux, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, show that the first gene regulation treatment for epilepsy is safe and well tolerated by patients with Dravet syndrome for whom antiseizure medications are not effective.

4 Mar 2026

Low-intensity preconditioning boosts neurological outcomes

The team led by Prof. Lin Zhu from Guangzhou Sport University have demonstrated that 4-week low-intensity treadmill exercise before the onset of an ischemic stroke can significantly reduce brain injury and improve neurological outcomes.

4 Mar 2026

GLP-1 drugs may be effective at treating and preventing substance use disorders

Researchers at Washington University School of Medicine in St. Louis show in a new study that GLP-1 medications may be effective at treating and preventing substance use disorders across all major addictive substances studied, suggesting these drugs target a common biological pathway underlying addiction.

4 Mar 2026

Georgia Tech receives major funding to develop lymphatic disease therapy

The Georgia Institute of Technology has been awarded up to $21.8 million from the Advanced Research Projects Agency for Health (ARPA-H) to deliver a first-of-its-kind therapy to patients with lymphatic disease.

4 Mar 2026

New fragmentome technology can detect early liver fibrosis and cirrhosis

Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free DNA (cfDNA) fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden.

4 Mar 2026

Armored CAR T cells overcome tumor defenses in solid cancers

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block their attack and fuel tumor growth.

4 Mar 2026