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Policy review demands better quality of life data in cancer clinical trials

A new policy review from Common Sense Oncology (CSO) and the European Organisation for Research and Treatment of Cancer (EORTC) calls for quality of life data to play a more central role in clinical trials evaluating adjuvant cancer treatments.

1 Oct 2026

Highlight Therapeutics presents positive Phase 2b topline results of intralesional BO‑112 in localized basal cell carcinoma as a late-breaker at EADV

Highlight Therapeutics, a clinical‑stage biotechnology company developing immune activators to transform the treatment of skin tumors, today announced positive results from the multicenter, single-arm Phase 2b SPOTLIGHT‑204 clinical trial evaluating BO‑112, a novel dsRNA-based intralesional treatment for patients with resectable primary low‑ and high‑risk basal cell carcinoma (BCC).

1 Oct 2026

Cognitive tests may not tell the whole story about memory concerns

This study highlights the link between blood biomarkers and dementia risk in subjective cognitive decline, emphasizing prevention and lifestyle changes.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Novel surgical technique restores clitoral sensation using buccal mucosa graft

For women who lose part of their clitoris because of vulvar cancer, a clitoral reconstruction procedure has now been developed for the first time. This comes forty years after the first penile reconstruction surgery. Results in the initial group of patients are encouraging.

1 Oct 2026

Real-world data reveals higher reported GLP-1 side effects in female patients

The second of a Series of papers presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Obstetrics, Gynaecology & Women's Health discusses the wide-ranging issues relating to use of GLP-1 RA drug use in women.

1 Oct 2026

GLP-1 receptor agonist exposure shows no link to major adverse pregnancy outcomes

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Obstetrics, Gynaecology & Women's Health shows that, following a review and meta-analysis of available studies, use of glucagon-like peptide-1 receptor agonists (GLP-1 RA) drugs for diabetes and weight management in women living with diabetes is not associated with adverse pregnancy outcomes in most cases.

1 Oct 2026

Study examines driving cessation in dementia and MCI

Flinders University researchers have investigated the reactions of people with dementia and mild cognitive impairment (MCI), in the hope of finding a process that best supports the person with dementia.

1 Oct 2026

Early-onset type 2 diabetes trial demonstrates significant 24-week fat loss

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Regional Health Americas journal shows that in people who have developed early onset type 2 diabetes (EOT2D) (aged under 45 years), around half these T2D cases can be reversed with a low-energy diet combined with a structured exercise program.

1 Oct 2026

Study examines the real-world use of GLP-1 RA drugs in children and young people

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has examined the real-world use of GLP-1 receptor agonist (GLP-1 RA) drugs in children and young people in Germany, Austria and Luxembourg.

30 Sep 2026

Insurance hurdles and costs hinder access to blood cancer drugs

Patients with blood cancers often face major insurance hurdles and significant out-of-pocket costs when trying to access specialty oral anticancer medications, according to a new nationwide study led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

30 Sep 2026

Wearable device can track changes in stroke-related arm movement impairment

A team led by University of Massachusetts Amherst researchers has developed a wearable wrist device powered by a machine-learning algorithm that can continually track changes in arm movement impairment caused by strokes.

30 Sep 2026

UC San Diego receives funding to establish the Polysubstance Addiction Research Center

Researchers from University of California San Diego have received a $12.6 million award from the National Institute on Drug Abuse (NIDA) to establish the Polysubstance Addiction Research Center (PARC), a multidisciplinary center designed to uncover the biological factors that contribute to addiction across multiple substances.

30 Sep 2026

High-dose taurine aggravates alcohol-induced liver injury, study shows

The researchers first tested whether taurine could compensate for reduced intestinal taurine availability and protect against alcohol-induced liver damage.

30 Sep 2026

Overall dietary patterns matter more for heart health than nutrients

A healthy, balanced dietary pattern, rather than one focused on individual nutrients or foods is key to maintaining heart health, according to a Scientific Statement issued by the American College of Cardiology and published in JACC, its flagship journal.

30 Sep 2026