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New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

Scientists create large library of mitochondrial DNA mutant models

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

6 Apr 2026

New guidelines aim to improve concussion care for first responders

Management of sports-related concussions has come a long way in the past 25 years: Once considered a minor problem involving minimal time out of the game, a severe knock to the head is now assessed as a potential traumatic brain injury and, if confirmed, requires a structured recovery and an average wait of 13 days before play resumes.

6 Apr 2026

Study shows how blind people map surroundings using sound

Some blind people use returning echoes from their own mouth clicks to perceive external surroundings, or echolocation.

6 Apr 2026

New target identified to overcome resistance in neuroendocrine tumors

Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells.

6 Apr 2026

Prickly pear may pack a surprising punch against metabolic syndrome

This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made.

6 Apr 2026

Study shows masculine depression is not just a male mental health pattern

Researchers found that depressed inpatients with high masculine depression scores had a substantially greater acute mental health burden across multiple symptom domains, even after accounting for overall depression severity. The paper also found this pattern was not specific to men, supporting “masculine depression” as a descriptive, sex-independent behavioral profile rather than a male-only condition.

6 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026

Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

Mayo Clinic researchers developed an experimental nanotherapy that delivers two cancer drugs directly to brain tumors, according to a study published in Communications Medicine.

6 Apr 2026

JMIR Publications' new article showcases the transformative potential of precision oncology

JMIR Publications today announced the release of a timely new article in its News and Perspectives section, showcasing the transformative potential of precision oncology.

6 Apr 2026

Remote monitoring technology helps Brooklyn resident manage high blood pressure

When 57-year-old Brooklyn resident Timothy Rhonda visited Park Ridge Family Health Center at NYU Langone with dangerously high blood pressure, he worried he might once again end up in the hospital.

6 Apr 2026

Study finds increasing rates of therapy-related acute myeloid leukemia

Some therapies used to treat cancer may increase the risk of later developing cancers that affect the blood.

6 Apr 2026

Irregular bedtimes double heart risk for those getting below 8 hours

Irregular sleep timing significantly impacts heart health, with inconsistent bedtimes linked to a higher risk of major cardiovascular events over a decade.

6 Apr 2026

Low birthweight increases stroke risk independent of adult BMI

In new research to be presented at this year's European Congress on Obesity (ECO2026) in Istanbul, Turkey (12-15 May), researchers show an increased risk of stroke in young adulthood for children of low birthweight, independent of their body mass index (BMI) as young adults or gestational age at birth.

3 Apr 2026

Toxic RNA drives progressive heart damage in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that leads to muscle weakness and wasting, but also affects the brain, the gastrointestinal tract and the heart.

3 Apr 2026

Study finds gaps in preventive care for women with diabetes

Physicians are less likely to provide preventive care such as conception counseling and some cancer screenings to women with diabetes than they do for women without the disease, a UCLA-led study suggests.

3 Apr 2026

Metabolic pathways drive progression from pancreatic lesions to cancer

Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate.

3 Apr 2026

COCOON trial protocol halves skin toxicities in lung cancer treatment

A new research perspective was published in Volume 13 of Oncoscience on March 11, 2026, titled "Early success of the COCOON trial: Preventing dermatologic adverse events in first-line EGFR-mutant NSCLC."

3 Apr 2026

Researchers uncover a chain of molecular events behind early brain changes in Alzheimer's

For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer's disease, their brain activity may begin changing long before any memory problems appear.

3 Apr 2026

Study identifies a common hidden genetic cause of neurodevelopmental disorder in children

Researchers identified biallelic variants in RNU2-2 as the cause of a recessive neurodevelopmental disorder marked by intellectual disability, global developmental delay, and frequent seizures. The study suggests this condition may be the most prevalent known recessive neurodevelopmental disorder currently diagnosable by sequencing, with RNA data pointing to a loss-of-expression mechanism.

2 Apr 2026