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Meal and sleep timing play key roles in diabetes prevention

High-resolution digital tracking reveals how daily habits, meal timing, sleep, and physical activity shape metabolic risk for type 2 diabetes. Meal timing, sleep patterns, and activity windows each play distinct roles in insulin resistance and glucose control.

12 Jun 2025

New nanopore sequencing assay advances fragile X syndrome carrier screening

Researchers have developed an innovative new nanopore sequencing assay to identify carriers of fragile X syndrome (FXS), the leading cause of monogenic autism spectrum disorder and inherited intellectual disabilities.

12 Jun 2025

APOE gene variants influence metabolic patterns linked to aging and Alzheimer’s risk

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 3, 2025, titled "APOE genotype and biological age impact inter-omic associations related to bioenergetics."

12 Jun 2025

Chronic hyponatremia causes anxiety-like behaviors by disrupting brain chemistry

Hyponatremia, or low blood sodium concentration, is typically viewed as a symptomless condition-until recently.

12 Jun 2025

Cholesterol shields cancer cells from heat treatment in hyperthermia therapy

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some tumor cells' unexpected heat resistance.

12 Jun 2025

Gut microbes offer clues for early detection of pancreatic cancer

Pancreatic cancer is a severe illness and major challenge in cancer medicine since it is difficult to diagnose, while potential therapies are scarce.

12 Jun 2025

Lower oral microbiome diversity linked to higher depression symptoms

A rich and varied mix of microbes in the mouth, particularly bacteria, is not only important for our oral health, but may hold clues for other conditions.

12 Jun 2025

Telehealth does not increase risk of substance use disorder in ADHD patients

Telehealth can make health care easier to access for patients with attention-deficit/hyperactivity disorder (ADHD) who need treatment, but experts worry about an increased risk of substance use disorder for patients being prescribed controlled medications such as stimulants for ADHD during these appointments.

12 Jun 2025

Peripheral arterial disease leads to more leg amputations in deprived communities

Leg amputation rates caused by arterial disease are four times as high in the most disadvantaged areas in England.

12 Jun 2025

Exercise targets specific brain cells to protect against Alzheimer’s

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical University have identified specific brain cell types that responded most to exercise.

12 Jun 2025

Global differences shape how doctors approach ALS ventilation decisions

A new study reveals striking international differences in how doctors approach the sensitive issue of tracheostomy invasive ventilation (TIV) for patients with amyotrophic lateral sclerosis (ALS).

12 Jun 2025

New large-scale study maps early triggers of Alzheimer’s protein aggregation

A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates found in Alzheimer's disease, pointing towards a new potential therapeutic target.

12 Jun 2025

Telehealth-based care program boosts function and mood in seniors with cancer

New research in the June 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network found that older people with cancer had better daily functioning, improved mood, stronger illness understanding, and a higher quality of life if they participated in a telehealth-based care program called Geriatric Assessment-Guided Intervention-Supportive Care (GAIN-S).

12 Jun 2025

Non-prescribed ketamine use rises sharply across the UK

The rise in non-prescribed ketamine use across the UK in recent years is a cause for concern, say doctors in The BMJ today.

12 Jun 2025

Healthier lifestyle choices could mitigate telomere length-associated brain disease risks

Scientists from Mass General Brigham explored the associations between telomere length-which decreases as a person ages or is exposed to unhealthy environments-and the risk for age-related brain diseases.

12 Jun 2025

Bitter 'supertaster gene' tied to bipolar disorder and poor kidney function

People who carry a bitter 'supertaster gene' have been linked to various health conditions including bipolar disorder and poor kidney function, University of Queensland researchers have found.

12 Jun 2025

Long term use of desogestrel linked to small increase in brain tumor risk

Taking the progestogen-only contraceptive pill desogestrel continuously for more than five years is associated with a small increased risk of developing a type of brain tumor called an intracranial meningioma, finds a study from France published by The BMJ today.

12 Jun 2025

Personalized model offers better blood pressure estimates from ankle measurements

A new method improving the accuracy of interpreting blood pressure measurements taken at the ankle could be crucial for people who cannot have their arm blood pressure measured.

12 Jun 2025

Rutgers study challenges FDA warning on antiseizure drug

Rutgers Health researchers found that lamotrigine, a widely prescribed antiseizure medication, to be safe in older adults with epilepsy, contrary to a safety warning by the Food and Drug Administration (FDA).

11 Jun 2025

Healthy lifestyle habits may shield aging cells from brain disorders

Stroke and dementia as well as late-life depression are more common in people who have a biomarker of aging called short leukocyte telomere length, according to a study published on June 11, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

11 Jun 2025