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Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

24 Sep 2026

Multiple immunosuppressive therapies increase infection risks for cancer patients

Retrospective analysis of more than 20,000 patient records identifies opportunities for risk-mitigating approaches in certain patient populations.

24 Sep 2026

Five research teams secure funding for frontotemporal dementia studies

The Kissick Family Foundation, in partnership with the Milken Institute Science Philanthropy's Accelerator for Research and Collaboration (SPARC), today announced five research teams selected to receive a total of $2.5 million through the third funding cycle of the Kissick Family Foundation Frontotemporal Dementia (FTD) Grant Program.

24 Sep 2026

AI tool provides early warning for organ failure in acute pancreatitis

Acute pancreatitis (AP) is one of the most common acute digestive disorders worldwide, and its most feared complication-persistent organ failure-drives mortality rates of 30% to 50%.

24 Sep 2026

Kidney rhythm mismatch linked to dangerous nighttime high blood pressure

Most people's blood pressure falls by 10 to 20 per cent while they sleep, giving the heart and blood vessels a chance to recover. But for some people, that nighttime dip never happens.

24 Sep 2026

Lund University gets $19.4 million grant for Alzheimer’s blood test

Alzheimer’s researcher Sebastian Palmqvist has been awarded USD 19.4 million (SEK 190 million) from the US National Institutes of Health (NIH), through its National Institute on Aging (NIA).

24 Sep 2026

Less is more: Exercise rivals common pain meds

From osteoarthritis to a splitting migraine, when you’re experiencing pain, exercise can seem like the last thing you want or think you should do. But according to new Adelaide University research it could be one of the most effective ways to help ease your symptoms.

24 Sep 2026

GLP-1 drugs may influence chronic pain through gut-brain and immune pathways

Researchers reviewed evidence linking GLP-1 and GLP-1 receptor agonists to chronic pain modulation through gut microbial, neuroimmune, vagal, and metabolic pathways, with the strongest clinical evidence currently involving knee osteoarthritis and idiopathic intracranial hypertension headache. Much of the proposed biology remains supported by preclinical research, and human studies have yet to establish that GLP-1RA-induced changes in the gut microbiome directly cause pain relief.

24 Sep 2026

Breath test shows promise for identifying cancerous lung nodules

The human breath could help identify cancerous lung nodules negating the need for invasive testing.

23 Sep 2026

Global appendicitis study reveals major inequalities in surgical care

A new global study into appendicitis has found that there are major inequalities in care, with some countries having little access to CT imaging or minimally invasive surgery - resulting in poorer patient outcomes.

23 Sep 2026

Semaglutide’s heart benefits may extend beyond weight loss

Semaglutide is known to reduce the risk of serious heart disease. However, a new study published in the European Heart Journal today (Thursday) suggests that this effect cannot not be entirely explained by patients losing weight on the drug.

23 Sep 2026

Nearly 60% of hypertension cases remain undetected in England

Researchers from Oxford Population Health analyzed clinic blood pressure measurements collected by Our Future Health, the UK's largest health research programme, from participants who enrolled between 2022 and 2025.

23 Sep 2026

Frailty linked to greater cognitive impairment risk in men with chronic kidney disease

New research from the University of Colorado Anschutz Department of Medicine is shedding light on how women and men with chronic kidney disease (CKD) may fare differently as they age and their disease progresses.

23 Sep 2026

Diabetes medication adherence remains low among disadvantaged patients

A new study led by UCLA Health found that a large percentage of disadvantaged patients are not taking their diabetes medications consistently.

23 Sep 2026

Exercise offers broad pain relief across acute and chronic conditions

From osteoarthritis to a splitting migraine, when you're experiencing pain, exercise can seem like the last thing you want or think you should do. But according to new Adelaide University research it could be one of the most effective ways to help ease your symptoms.

23 Sep 2026

Transient ischemic attacks linked to increased long-term dementia risk

Having a transient ischemic attack (TIA) is associated with an increased risk of developing dementia, according to a new study published September 23, 2026, in Neurology, the medical journal of the American Academy of Neurology.

23 Sep 2026

Stroke rates nearly doubled among younger adults over three decades

Stroke is becoming more common among younger adults, according to a study published September 23, 2026, in Neurology, the medical journal of the American Academy of Neurology.

23 Sep 2026

Obesity disrupts ILC2 metabolism through increased fatty acid uptake

A group of innate immune cells, known as group 2 lymphoid cells (ILC2), are essential for maintaining a stable metabolism in adipose tissue. Obesity significantly impairs the number and function of ILC2 cells, leading to the progression of metabolism-related inflammation.

23 Sep 2026

PsychAD studies map molecular mechanisms across major brain disorders

Research led by Mount Sinai scientists within the PsychAD Consortium, a large-scale, multidisciplinary initiative launched in 2019 with support from the National Institute on Aging (NIA), is featured in a landmark collection of nine papers published across the Nature family of journals that maps the molecular mechanisms underlying Alzheimer's disease, Parkinson's disease, schizophrenia, and other brain disorders.

23 Sep 2026

Menopause leaves a blood protein signature linked to brain aging and Alzheimer’s risk

Researchers identified a 16-protein blood signature associated with menopause that tracked more strongly with reproductive hormones than chronological age and was largely replicated in an independent UK Biobank cohort. Higher menopause proteomic scores were also associated with less favorable proteomic aging estimates and poorer cognitive outcomes in older women, including incident Alzheimer’s dementia, although the observational evidence does not establish causality.

23 Sep 2026