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New partnership aims to expand global access to sickle cell gene therapy

Caring Cross, a 501(c)(3) non-profit dedicated to improving access to advanced therapies, and Boston Children's Hospital today announced a collaboration to provide a sustainable, affordable pathway for patients to access stem cell gene therapies for the treatment of Sickle Cell Disease (SCD).

22 Jan 2026

Cancer vaccines enter a new era of personalized immunotherapy

A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments.

22 Jan 2026

Exercise variety, not just volume, is tied to longer life

Researchers analysed nearly three decades of data from more than 111,000 adults to examine whether the variety of physical activities people perform is linked to long-term survival. They found that engaging in a broader range of activity types was associated with lower all-cause mortality, independent of total exercise volume.

22 Jan 2026

FDA warns consumers about fake cancer cures sold online

Beware of products claiming to cure cancer on websites or social media platforms, such as Facebook and Instagram. According to Nicole Kornspan, M.P.H., a consumer safety officer at the U.S. Food and Drug Administration (FDA), they're rampant these days.

22 Jan 2026

When you eat matters: early time-restricted eating improves metabolic health

Time-restricted eating improves several metabolic outcomes compared with usual diets, with benefits observed for body weight, adiposity, blood pressure, insulin, glucose, and triglycerides. Early eating windows consistently outperform late eating, while the optimal duration of food intake remains uncertain.

22 Jan 2026

Brain complexity declines in Alzheimer's disease

As individuals with Alzheimer's disease (AD) move from the mild cognitive impairment stage to moderate and severe dementia, complex awareness deteriorates although lower-level sensory awareness is relatively maintained.

22 Jan 2026

Pre-surgical medication use grows for pancreatic, gynecologic, and abdominal lining cancers

The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers, often allowing less invasive surgery and helping clinicians assess how a patient's cancer responds to medication to guide the most effective treatment options.

22 Jan 2026

Moffitt researchers develop a new way to predict how cancer cells evolve

Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment.

22 Jan 2026

FIU's personalized cancer treatment shows promise

Researchers at FIU are advancing a personalized approach to cancer treatment that is showing increasingly promising results for patients with hard-to-treat disease, supported by new philanthropic investment that is helping expand the science behind the work.

22 Jan 2026

Discovery explains why people with IBD have higher risk of colorectal cancer

A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal cancer, according to a preclinical study by Weill Cornell Medicine investigators.

22 Jan 2026

Alterations in liver metabolism experienced by individuals with Down syndrome

Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels of bile acids in the bloodstream and other biomarkers of liver dysfunction.

22 Jan 2026

Researchers decipher a key mechanism that controls pancreatic cancer growth

Could this mark a shift in how we think about cancer therapy? At least in the laboratory, evidence suggests it may be.

22 Jan 2026

Expert guidance on fecal microbiota transplantation in liver disease

The gut microbiota plays a crucial role in maintaining host health and liver function. Fecal microbiota transplantation (FMT), an emerging therapeutic modality, has demonstrated promising potential in the treatment of chronic liver diseases.

22 Jan 2026

Myosteatosis: An emerging predictor of outcomes in chronic liver disease

Myosteatosis, the pathological infiltration of fat into skeletal muscle, is increasingly recognized as a key predictor of poor clinical outcomes across a spectrum of liver diseases.

22 Jan 2026

See through the skin: New technology spots early heart disease warning signs

Researchers from Helmholtz Munich and the Technical University of Munich (TUM) have developed "fast-RSOM", a new imaging technology that can capture detailed images of the smallest blood vessels directly through the skin – without the need for invasive procedures.

22 Jan 2026

High BMI linked to vascular dementia risk

High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular + unspecified dementia), according to new research from the University of Bristol and University Hospital of Copenhagen (Rigshospitalet and Herlev-Gentofte hospital).

22 Jan 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Super-enhancers: Cancer's double-edged sword of growth and DNA damage

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive unusually intense gene activity.

22 Jan 2026

New medical LLM detects depression in women via WhatsApp audio analysis

A new medical large language model (LLM) achieved over 91 percent accuracy in identifying female participants diagnosed with major depressive disorder after analyzing a short WhatsApp audio recording where participants described their week, according to a study published January 21, 2026 in the open-access journal PLOS Mental Health by Victor H. O. Otani, from Santa Casa de São Paulo School of Medical Sciences and Infinity Doctors Inc., Brazil, and colleagues.

22 Jan 2026

Study identifies a powerful strategy to overcome drug resistance in breast cancer

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6.

22 Jan 2026