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ESMO updates precision oncology framework to improve targeted therapies

ESMO has published version 2 of the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT), a major update to the internationally recognized precision oncology framework that helps oncologists assess the clinical relevance of molecular alterations and match patients with the most appropriate targeted therapies.

22 Oct 2026

ESMO introduces new set of principles to strengthen the communication of cancer research

The new 'ESMO Principles for Humanising Scientific Reporting' aim to strengthen the communication of oncology research, connect scientific evidence with patient relevance, and support a more patient-centered approach to cancer research communication.

22 Oct 2026

Intermittent fasting combined with exercise promotes weight loss in obese adults

A trial led by the Joint University Institute for Sport and Health shows benefits regarding weight, body fat, and cardiorespiratory fitness in people with obesity.

22 Oct 2026

Obesity impairs key immune cells but bariatric surgery reverses damage

New Maynooth University (MU) research led by the Department of Biology's Dr Ciara Flynn, working within the research group of Prof Andrew Hogan at the Kathleen Lonsdale Institute for Human Health Research has found that obesity can impair key immune cells that help protect the body against infection and cancer.

22 Oct 2026

AGA/AASLD joint guideline evaluates newer medications for primary biliary cholangitis

For the first time, a joint guideline from the American Gastroenterological Association (AGA) and American Association for the Study of Liver Diseases (AASLD) evaluates newer medications for primary biliary cholangitis (PBC), the most common cholestatic disease in adults.

22 Oct 2026

Young cancer survivors face critical gaps in follow-up care

Young adult cancer survivors face gaps in follow-up care caused by factors including geographic mobility and insurance changes, according to an analysis by UTHealth Houston researchers.

22 Oct 2026

Half-matched bone marrow transplants show high survival in young aplastic anemia patients

Researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins Children's Center report that bone marrow transplant using half-matched family donors achieved a 96% survival rate among children, adolescent, and young adult patients with severe aplastic anemia, a rare, life-threatening disorder in which the bone marrow fails to produce enough healthy blood cells.

22 Oct 2026

Community health workers help patients piece their lives back together

For Georgieanna Pierre-Paul-who wants everyone to call her Gee-the most important part of her job may be a comfortable pair of shoes.

22 Oct 2026

Artificial intelligence in stroke rehabilitation: A structured clinical review

Stroke is a major cause of long-term disability, and recovery varies substantially across motor, cognitive, communication, and activities-of-daily-living domains, making continuous assessment and individualized rehabilitation essential.

22 Oct 2026

Are shared fryers really off-limits for people with celiac disease?

A study finds most French fries and tortilla chips from shared fryers contain low gluten levels, suggesting revised dietary advice for celiac disease is needed.

22 Oct 2026

Depression profile linked to disrupted sleep and poorer treatment responses

This study uncovers a circadian depression subtype, revealing links between sleep patterns, symptom severity, and antidepressant response in a large cohort.

22 Oct 2026

New study explores psychedelic therapy for co-occurring cocaine addiction and depression

A team of UTHealth Houston researchers has been awarded a five-year, $3.4 million grant to study whether psilocybin-assisted therapy is a viable treatment option for individuals with co-occurring cocaine use disorder and major depressive disorder.

22 Oct 2026

New national trial platform aims to accelerate Alzheimer's disease prevention

Researchers from the University of California San Diego will join a collaboration as part of a federal award of up to $41 million to launch a national effort aimed at accelerating the search for treatments that could prevent or slow Alzheimer's disease.

22 Oct 2026

Stem cell therapies may need new protein quality control standards

Current Good Manufacturing Practice (GMP) standards for cell therapies assess identity, viability, sterility, and genetic stability. For extracellular vesicle (EV) products, Minimal Information for Studies of Extracellular Vesicles (MISEV2023) guidance adds particle size, concentration, markers, morphology, contaminants, endotoxin, and assays.

22 Oct 2026

Cardiac events account for 43% of on-duty firefighter deaths

Cardiac events account for nearly half of all on-duty firefighter deaths in the U.S.—a proportion that has steadily increased over the past three decades, according to a Cedars-Sinai Health Sciences University study.

22 Oct 2026

Accelerated TMS cuts depression treatment time from six weeks to three

Transcranial magnetic stimulation (TMS) has proved to be a very effective non-invasive treatment for people with severe depression who have not had success with medication. But traditional TMS has one significant drawback: time.

21 Oct 2026

Inspire device offers new sleep apnea treatment for teens with Down syndrome

For some adolescents with Down syndrome, neither surgery to remove the tonsils nor a CPAP machine provides a workable solution for obstructive sleep apnea.

21 Oct 2026

AI-powered eye tracking could personalize virtual reality therapy for chronic pain

Combining artificial intelligence (AI) with eye tracking in virtual reality could one day help personalize treatment for millions living with chronic pain, according to world-first research from the University of East Anglia.

21 Oct 2026

Global study aims to map brain changes across eight psychiatric disorders

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC will lead a worldwide effort to map how eight common psychiatric disorders affect brain function, supported by a five-year, $3.2 million grant from the National Institutes of Health.

21 Oct 2026

Newer anticoagulants linked to fewer strokes and deaths after brain bleeds

For people with atrial fibrillation (AFib), an irregular heartbeat, and intracranial hemorrhage, a type of stroke also known as a brain bleed, anticoagulant use was associated with a lower risk of an ischemic stroke and death, according to a new study published October 21, 2026, in Neurology®, the official medical journal of the American Academy of Neurology.

21 Oct 2026