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Inflammatory macrophages identified as drivers of chronic joint osteoarthritis

Researchers have identified a group of inflammatory macrophages that drive osteoarthritis by sustaining inflammation in the synovium – a layer of connective tissue within joints – and show that they can target these immune cells to treat the disease in mice.

28 Oct 2026

Researchers identify protein that drives chronic inflammation in psoriasis

In new preclinical studies, researchers have identified a protein that propels a vicious cycle of skin inflammation in psoriasis.

28 Oct 2026

Dual-targeting antibody successfully tackles multiple tumor types in mice

A novel antibody therapy empowers the immune system's tumor-fighting capabilities in mice by targeting immune-suppressing T cells with greater precision than previous approaches, according to new work.

28 Oct 2026

University of Utah researchers discover backup energy system in the heart

The heart is the hardest-working muscle in the body, beating constantly no matter what the body's energy reserves look like.

28 Oct 2026

Mindfulness-based behavioral therapy changes brain responses to reduce opioid cravings

Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral therapy used alongside medication treatment, may help people with opioid use disorder respond differently to drug-related cues and natural rewards, according to a randomized clinical trial led by researchers at the Icahn School of Medicine at Mount Sinai.

28 Oct 2026

Michigan Medicine study reveals how diabetes drug reduces stroke risk

For millions living with type 2 diabetes, heart disease remains one of the greatest threats to their health.

28 Oct 2026

Targeted drug combination extends survival in advanced kidney cancer

Results of a phase 1/2 trial led by Roswell Park Comprehensive Cancer Center show that combining the targeted therapies bevacizumab (Avastin) and pazopanib (Votrient) significantly extends both progression-free and overall survival in patients with the most common type of kidney cancer.

28 Oct 2026

Landmark studies map how genetic differences drive human diseases

In three landmark studies published in Nature today, Australian researchers have made major advances in our understanding of how genetic differences between people influence disease.

28 Oct 2026

Study identifies common mechanism behind widespread cancer mutations

A family of mutations seen in about 20% of human cancers drives malignancy by changing the accessibility of genes to a particular regulatory protein, according to a study by Weill Cornell Medicine investigators.

28 Oct 2026

New score predicts thrombosis risk in hospitalized pancreatitis patients

Professor Julia Mayerle and colleagues from LMU University Hospital Munich have developed an admission-based score intended to identify pancreatitis patients more likely to be diagnosed with thrombosis during hospitalization.

28 Oct 2026

Review highlights essential neurological considerations for gender dysphoria care

Gender dysphoria involves distress caused by a mismatch between a person's gender identity and sex assigned at birth.

28 Oct 2026

Overcoming cancer stigma requires policy changes and public education

Cancer-related discrimination arises from long-lasting cultural and institutional misconceptions, with significant impacts on every part of a person's quality of life and health – and Flinders University researchers say it requires coordinated policy, legal, institutional and public education responses for change to occur.

28 Oct 2026

NIOX® launches NIOX PRO®, their next generation FeNO testing device

NIOX Group plc, a global leader in fractional exhaled nitric oxide (FeNO) testing, has announced the launch of NIOX PRO®, its next-generation FeNO testing device designed to support healthcare professionals in the diagnosis and management of asthma, COPD and other inflammatory airway diseases.

From NIOX Group PLC 28 Oct 2026

UK study identifies ways to improve bowel cancer detection in IBD patients

The first UK-wide analysis of bowel screening for patients with inflammatory bowel disease (IBD) has identified opportunities to improve the early detection of cancer.

27 Oct 2026

Lab-on-a-chip technology helps predict childhood leukemia treatment responses

More than 120,000 people in the U.S. are living with acute lymphoblastic leukemia (ALL), and 6,000 new cases are diagnosed each year. Of those, more than 3,500 will be in children.

27 Oct 2026

New research center aims to accelerate hepatitis C vaccine development

The shifty hepatitis C virus (HCV) has a knack for outmaneuvering the immune system. Its secret is an especially high mutation rate, which has generated an abundance of viral variants with extreme genetic diversity.

27 Oct 2026

Wildfire prevention power shutoffs linked to increased risk of acute respiratory illness

The prevalence of wildfires and co-occurring power outages is increasing in the United States. A study published October 27th in PLOS Medicine by Lauren Blair Wilner, University of Washington, USA, and colleagues suggests public safety power shutoffs aimed at preventing wildfires are associated with an increased risk of acute respiratory illness.

27 Oct 2026

Non-drug and non-surgical low back pain treatments are highly cost-effective options

Non-drug and non-surgical treatments for low back pain, including psychological support, exercise and self-management strategies are cost-effective interventions, according to a study published October 27th in the open access journal PLOS Medicine by Manuela Loureiro Ferreira from the George Institute for Global Health, Australia, and colleagues.

27 Oct 2026

Mutant protein variant explains dominant inheritance of genetic immunodeficiency

New research shows how a mutant form of a protein named STAT3 causes a genetically dominant immunodeficiency.

27 Oct 2026

High-scoring endocrinologists are more likely to prescribe key diabetes drugs

Endocrinologists who scored highest on the American Board of Internal Medicine's Longitudinal Knowledge Assessment (LKA®) were more likely to prescribe a key diabetes drug class following a treatment guidelines update compared to doctors with lower scores.

27 Oct 2026