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New initiative aims to tackle bronchiectasis underdiagnosis in America

The American Thoracic Society (ATS) today announced a major quality improvement initiative aimed at tackling the persistent and widespread underdiagnosis of bronchiectasis in the United States.

30 Apr 2026

New research shows weight loss is possible without GLP-1

Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.

30 Apr 2026

Maternal screening could help prevent deadly forms of leukemia

A deadly form of leukemia may be stopped before it ever develops by introducing targeted maternal screening in the United States, according to new research.

30 Apr 2026

Antibiotic minocycline shows potential for treating panic disorder symptoms

A study supported by FAPESP shows that small doses of the antibiotic minocycline may help treat panic disorder.

30 Apr 2026

From killers to strategists: CAR T cells enter their multifunctional era

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

30 Apr 2026

Survey reveals silica dust risks for Australia’s tunnel workers

The responses to a national survey published today have revealed tunnel construction workers across Australia say they face significant exposure to silica dust, a hazardous dust that can cause incurable diseases like silicosis and lung cancer.

29 Apr 2026

Maternal weight before pregnancy may shape toddlers’ development

A nationwide Korean cohort study of 258,367 mother-child pairs found that maternal pre-pregnancy BMI was associated with developmental delay risk in children aged 18 to 36 months. Children of underweight mothers showed modest early risks that later attenuated, while obesity-related risks persisted across developmental domains.

29 Apr 2026

Brief walking breaks help the body control sugar after carb-rich meals

Brief brisk walking breaks during prolonged sitting improved post-meal interstitial glucose responses in healthy adults after carbohydrate-rich meals, with the strongest effects seen in women. Gluteal fat showed a more stable glucose pattern than abdominal fat, suggesting it may help buffer carbohydrate-related glucose rises through depot-specific uptake and lipid-synthesis pathways.

29 Apr 2026

AHA calls for lifelong brain health strategy to prevent cognitive decline

The AHA scientific statement calls for a life-course approach to brain health that integrates cognitive, emotional, behavioral, vascular, environmental, inflammatory, sleep, microbiome, and social factors. It highlights how early-life exposures, mental health, pollution, chronic inflammation, poor sleep, gut dysbiosis, and socioeconomic adversity may shape brain resilience and later-life cognitive decline.

29 Apr 2026

Researchers use light-activated nanozymes to treat aggressive brain tumors

Brain tumors cannot always be successfully treated with conventional therapies. A team from Empa and the hospital network HOCH Health Ostschweiz is therefore developing nanozymes that can attack cancer cells directly in the brain during tumor surgery.

29 Apr 2026

Multiple myeloma mortality rates decline with advances in targeted therapies

A new research paper was published in Volume 17 of Oncotarget on April 28, 2026, titled "Targeted therapeutics and U.S. population-level mortality trends in multiple myeloma: A SEER-based analysis from 1975 to 2023."

29 Apr 2026

New genetic risk test estimates inherited risk for cardiovascular conditions

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

29 Apr 2026

New hybrid molecule uses Trojan horse approach to treat obesity

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a "door opener" and delivers an additional metabolic modulator specifically into the target cells.

29 Apr 2026

Maternal antibodies provide lifelong protection against adult gum disease

Mothers provide a hidden immune legacy that protects their children's teeth long after weaning is over. A new study reveals how maternal antibodies act as early life architects, programming the mouth to resist aggressive bacteria and prevent the bone loss associated with adult gum disease.

29 Apr 2026

AGA update emphasizes lifestyle changes for effective hemorrhoid management

The American Gastroenterological Association (AGA) has released a new clinical practice update providing expert guidance on the diagnosis and treatment of hemorrhoids, a common condition affecting approximately 50% of people by age 50.

29 Apr 2026

Phone-based education significantly improves inhaler technique for COPD patients

Guiding people on how to correctly use inhaled medications via a phone-based program can help improve technique, according to a new study in the March 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open access journal.

29 Apr 2026

Nerve fibers within melanomas found to slow tumor growth

Nerve fibers within melanomas can slow the growth of these tumors, according to a study led by Weill Cornell Medicine investigators.

29 Apr 2026

New map reveals B cell clusters linked to faster diabetic kidney disease

A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells-specifically B cells-that are linked to faster disease progression.

29 Apr 2026

AI eye screening shows promise for detecting six metabolic diseases

Researchers developed Reti-Pioneer, an AI retinal imaging framework that screened for six endocrine and metabolic diseases using color fundus photographs and clinical metadata. The system showed moderate-to-strong performance across cohorts, improved specialist decision-making, and demonstrated promising, though still preliminary, potential for faster, scalable disease screening.

29 Apr 2026

Scientists redesign CAR-T cells to fight more than cancer

This review examines how CAR-T cell therapy is expanding beyond blood cancers into solid tumors, autoimmune diseases, chronic viral infections, and next-generation immune-cell platforms. It highlights promising engineering advances, including universal CAR-T cells, in vivo delivery, CAR-NK cells, and safety switches, while emphasizing unresolved challenges in durability, safety, scalability, and global access.

29 Apr 2026