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Scientists uncover protein-folding mechanism linked to diabetes progression

Origami masters turn simple sheets of paper into ornate sculptures. In the origami of life, our cells must fold proteins into specific three-dimensional shapes before they can carry out their biological jobs.

11 Jun 2026

Mesothelioma remains deadly despite declining asbestos exposure rates

Mesothelioma deaths and diagnoses continue to rise in the United States despite decades of asbestos regulation and reduced industrial use, according to a new national analysis from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

11 Jun 2026

Boston Children's joins landmark initiative to advance autism therapies

Boston Children's Hospital has been awarded up to $17.25 million to serve as a participating site within the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network, an international effort funded through Aligning Research to Impact Autism (ARIA).

11 Jun 2026

Oral semaglutide improves blood sugar, weight, and liver markers in real-world diabetes care

A nationwide Finnish registry study of 7,249 GLP-1RA-naïve adults with type 2 diabetes found that once-daily oral semaglutide was associated with 12-month improvements in HbA1c, body weight, lipid markers, and ALT.

11 Jun 2026

Trial finds prunes do not outperform calcium and vitamin D for male bone density

A one-year randomized trial found that daily prune supplementation did not improve total or lumbar spine bone mineral density in older men susceptible to, or with, osteopenia. Although some bone turnover biomarkers differed between prune and control groups, these changes did not translate into measurable bone density benefits beyond calcium and vitamin D3 supplementation.

11 Jun 2026

Oral GLP-1 drug elecoglipron helps adults lose up to 11.8% body weight

Once-daily oral elecoglipron produced dose-dependent weight loss in adults with obesity or overweight without diabetes, with mean reductions reaching 10.5% at 26 weeks and 11.8% at 36 weeks in the highest-dose weekly-titration group. The phase 2 trial found no evidence of a weight-loss plateau by 36 weeks, while gastrointestinal adverse events were common but generally manageable.

11 Jun 2026

FDA accepts immunotherapy drug for review in colon cancer treatment

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

11 Jun 2026

Metformin reduces long COVID risk according to ACTIV-6 clinical trial

New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed long COVID when started during acute COVID-19 infection.

11 Jun 2026

Texas Children’s Hospital and Baylor researcher joins ARIA IMPACT Network to advance autism therapies

Dr. Jimmy Holder, associate professor in pediatrics at Baylor College of Medicine and Principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, and his team have received a grant for up to $17.25 million from Aligning Research to Impact Autism (ARIA) to become a part of the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network.

11 Jun 2026

Intravenous statins during heart attack reduce cardiac muscle damage

Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner.

11 Jun 2026

Genetic study links liver enzyme to compulsive cocaine addiction

Researchers at the University of California San Diego have completed a massive genetic study that identifies key biological drivers of cocaine addiction, uncovering a potential new target for treatment that resides in the liver rather than the brain.

11 Jun 2026

Blood pressure control may be the key to optimizing stroke treatment after thrombectomy

Blood pressure management after thrombectomy for acute ischemic stroke may require a change in approach.

11 Jun 2026

Genetic screening of LOXHD1 variants guides early hearing loss intervention

Hearing loss is a common cause of disability worldwide, with anywhere between 30-60% of cases being caused by genetic factors. LOXHD1 is a gene integral to essential protein interactions responsible for maintaining normal hair cell function.

11 Jun 2026

Experts propose unified framework to advance the future of high-altitude medicine

As increasing numbers of people live, work, and travel at high altitudes, experts are calling for a major shift in how altitude-related health conditions are understood, diagnosed, and treated.

11 Jun 2026

New treatment platform delivers full-length mRNA for Duchenne muscular dystrophy

A new treatment platform developed by researchers at The University of Texas MD Anderson Cancer Center was able to deliver messenger RNA (mRNA) of the full-length DMD gene into preclinical models of Duchenne muscular dystrophy, successfully restoring the production of an important muscle protein, dystrophin, and dramatically improving muscle strength, endurance and function in vivo.

11 Jun 2026

Chronic pancreatitis care must expand beyond simple pain management

Chronic pancreatitis (CP) diminishes quality-of-life (QoL) across mobility, self-care, daily activities, mental health, and pain-not just abdominal discomfort-according to a new Mayo Clinic study available online on August 27, 2025, and published in Volume 9, Issue 1 of the Journal of Pancreatology on March 30, 2026.

11 Jun 2026

First-in-the-world gene therapy delivers missing gene directly to infant’s brain, marking historic milestone in precision medicine

An eight-month-old baby from Israel has become the first human ever to receive an experimental gene therapy designed to replace a missing gene responsible for a devastating neurological disease that until now offered no hope of survival.

11 Jun 2026

Viral DNA blood test accurately gauges post-surgery cancer recovery success

A new study by investigators from Mass General Brigham Cancer Institute found that an ultrasensitive blood test called HPV-DeepSeek could help identify which people with HPV-associated head and neck cancer still had cancer cells in their bodies after surgery and may benefit the most from additional treatments. Their results are published in Science Translational Medicine.

11 Jun 2026

Researchers isolate intact tumor microRNAs using antibody-conjugated nanowires

A research team in Japan has developed an efficient and minimally invasive cancer detection device that uses high-performance zinc oxide nanowires to selectively capture extracellular vesicles (EVs) from bodily fluids.

11 Jun 2026

A hidden immune pathway may help explain why Alzheimer’s inflammation persists

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.

11 Jun 2026