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Molecular mapping reveals hidden cellular programs in heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

12 Aug 2026

The coffee advice given to atrial fibrillation patients may deserve a rethink

The DECAF randomized trial found that adults with persistent atrial fibrillation or atrial flutter assigned to drink at least one cup of caffeinated coffee daily had a 39% lower hazard of recurrent clinically detected AF or flutter than those assigned to avoid coffee and caffeine. The findings challenge longstanding advice to routinely restrict caffeinated coffee in people with AF, while further research is needed to determine whether coffee itself provides a protective effect.

12 Aug 2026

How much do nuts matter for blood pressure? This study points to about a handful a day

A meta-analysis of eight prospective studies involving 143,380 participants found that higher nut consumption was associated with a lower risk of developing hypertension. Each 28 g/day increment was associated with a 20% lower relative risk in the linear analysis, while the modeled association appeared to level off at around one handful per day.

12 Aug 2026

Cannabis compounds may weaken glioblastoma response to chemotherapy and radiation

Several cannabinoids reduced chemotherapy- and radiation-induced apoptosis in glioblastoma cell models, with effects linked to reduced apoptotic priming, increased pro-survival signaling, and G1 cell-cycle arrest. The findings raise concern that cannabinoid exposure could interfere with some cancer treatments, although the results are limited to laboratory models and require in vivo and clinical validation.

12 Aug 2026

Researchers tracked biological aging for decades and found a striking pattern in women

Accelerated biological age in midlife was associated with higher risks of cardiovascular disease and death in both men and women over nearly three decades of follow-up. Women with accelerated biological age also showed a higher risk of dementia, although adding biological age to standard risk factors provided only minimal additional predictive value.

12 Aug 2026

How well you balance and move may say more about longevity than you think

Objective fitness testing in 13,423 older adults in Taiwan found that higher physical fitness was consistently associated with lower all-cause mortality over a median seven years. Balance and agility, lower-body strength, and cardiorespiratory fitness showed the strongest associations, while a composite fitness score produced the steepest mortality gradient.

11 Aug 2026

Childhood overweight linked to lower childbirth rates later in reproductive life

Women with childhood overweight or obesity trajectories had lower hazards of childbirth from their mid-20s onward, with the strongest associations emerging after age 30. Childhood BMI trajectories were generally not associated with diagnosed infertility, suggesting that biological infertility alone may not explain the reduced childbirth rates.

11 Aug 2026

Innovative youth mental health service model cuts costs and improves care

An innovative youth mental health service model can improve care and ease pressure on Canada's health-care system, a new study led by researchers at McGill University and the Douglas Research Centre demonstrates.

11 Aug 2026

IOC urges routine mental health screening for elite athletes

Sports bodies should prioritize routine screening and regular monitoring of elite athletes' mental health to tackle the high prevalence of mental health issues among this group, concludes an International Olympic Committee (IOC) consensus statement, published online in the British Journal of Sports Medicine.

11 Aug 2026

Stretchable catheter could help identify high-risk arterial plaque

We all know about plaque from dreaded trips to the dentist. But plaque can also build up inside the arteries, taking the form of fatty deposits that can potentially restrict blood flow.

11 Aug 2026

Genetic tool turns soft cancer cells into immune targets

Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of tumors.

11 Aug 2026

UH College of Pharmacy secures funding for three major health studies

University of Houston College of Pharmacy researchers have secured more than $1 million in new funding to support three separate studies targeting sepsis, Alzheimer's disease and related dementias, and depression in patients with sickle cell disease.

11 Aug 2026

New imaging model can detect early brain changes in Huntington's disease

Researchers have shown that an imaging model can detect microstructural abnormalities in the brain associated with Huntington's disease, potentially offering a new method for monitoring disease progression and evaluating new treatments.

11 Aug 2026

EuroSpA study links country income to arthritis treatment outcomes

A study initiated by the European Spondyloarthritis Research Collaboration Network (EuroSpA) examined whether where patients with psoriatic arthritis (PsA) or axial spondyloarthritis (axSpA) live is associated with the severity of their disease, when they begin advanced treatment, and how long they continue that treatment.

11 Aug 2026

Senescent brain immune cells secrete protein linked to cognitive decline

Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine.

11 Aug 2026

Huge philanthropic grant funds pioneering stem cell-based heart attack therapy

In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell Center, Chuck Murry, MD, PhD, $28.7 million to advance a clinical trial testing a stem cell-based therapy designed to regenerate damaged tissue after a heart attack.

11 Aug 2026

Shared cellular pathway drives neurodegeneration in rare childhood dementia and Alzheimer’s

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

11 Aug 2026

Nocturnal micro-awakenings linked to genetic risk of Alzheimer's disease

What if certain signs of the disease were to manifest themselves subtly during sleep, long before the first memory problems appear? This is the line of inquiry being explored by a team of researchers at ULiège, with the support of the Stop Alzheimer's Foundation.

11 Aug 2026

Waist size predicts heart disease risk better than body mass index

The size of a person's midsection is a better indicator of cardiovascular disease risk when compared to their body mass index (BMI) alone, according to a study published in JACC, the flagship journal of the American College of Cardiology.

11 Aug 2026

HonorHealth begins trial of dendritic cell vaccine for advanced melanoma

Physicians at HonorHealth Research Institute have begun a clinical trial of a new, potentially more powerful, treatment for fighting advanced melanoma, using the immune system's dendritic cells to create a vaccine.

11 Aug 2026