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Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

Review highlights solute carriers as targets for central nervous system disorders

Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell membranes and are essential for brain metabolism and neuronal communication.

10 Sep 2026

New treatment approach preserves organs, improves survival in head and neck cancer patients

Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.

10 Sep 2026

Symptomless liver condition linked to heart and kidney disease

A common liver condition thought to be harmless could be dramatically increasing the risk of heart disease, kidney failure and premature death, according to a new review led by University of Manchester and Northern Care Alliance NHS Foundation Trust researchers.

10 Sep 2026

Generative AI-driven drug Rentosertib enters Phase III trial for idiopathic pulmonary fibrosis

Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, today announced that it has dosed the first patient with Rentosertib (known as ISM001-055 / INS018_055) in GENESIS-IPF-3, a Phase III clinical trial (NCT07687459, CTR20262475) at Peking Union Medical College Hospital, while Shanghai Pulmonary Hospital has also enrolled its first patient on the same day.

10 Sep 2026

Nighttime light exposure may alter heart structure and function

Exposure to light during the nighttime is linked to important and potentially harmful changes to the structure and function of the heart, according to a study of more than 11,000 people published in the European Heart Journal today (Thursday).

10 Sep 2026

Tizanidine looked promising early in a migraine trial, but the benefit did not last

A randomized, double-blind, placebo-controlled trial found that low-dose tizanidine did not provide sustained reductions in headache burden over 12 weeks in people with episodic migraine, despite a transient improvement with the 1 mg dose at week 4. Exploratory analyses suggested that smoking and sex may influence tizanidine exposure, while sex-specific efficacy signals remained hypothesis-generating and require confirmation.

10 Sep 2026

Dementia prevention should look beyond individual choices, study finds

Efforts to prevent dementia may be placing too much responsibility on people's choices while overlooking the wider social and environmental conditions that shape brain health, according to new Curtin University research published in The Lancet Public Health.

9 Sep 2026

Blood protein profiling could improve rare disease diagnosis

Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

9 Sep 2026

Spleen imaging features may reveal coronary artery disease risk

A new study led by investigators from Mass General Brigham reveals that certain features in the spleen hidden within imaging scans may signal a person's risk of coronary artery disease (CAD), suggesting targets for prevention and treatment.

9 Sep 2026

Chaotic tumor environments may trigger cancer cell invasion

In 2024, malignant tumors caused more than 21,300 deaths in Austria, 4.7% more than in 2014. Faced with a similarly pressing global challenge, scientists are striving to better understand what drives cancer cells to grow, spread, and invade healthy tissue.

9 Sep 2026

Early B-cell therapy linked to better MS disease control

For people recently diagnosed with multiple sclerosis (MS), early treatment choices were associated with only slight differences after two years, based on the first treatment they used, according to a study published September 9, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

9 Sep 2026

Protein-based MRI agent detects tiny lung cancer metastases

A multi-institutional research team led by Georgia State University Regents' Professor Emerita of Biochemistry and Biophysical Chemistry Jenny J. Yang has developed a new class of protein-based MRI contrast agent that detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.

9 Sep 2026

The link between PM2.5 and ADHD held up after researchers tested other explanations

Using two decades of U.S. county-level data, researchers found that long-term PM2.5 exposure was robustly associated with higher childhood ADHD prevalence, while associations with low birth weight and diabetes weakened after accounting for county-specific temporal trends. The ADHD association persisted after socioeconomic, demographic, state-level, exposure-period, and spatial adjustments, although the ecological study cannot establish an individual-level causal relationship.

9 Sep 2026

The link between fish and pregnancy hypertension may start before conception

In a nationwide Japanese cohort of more than 86,000 women, higher fish intake before pregnancy was associated with lower odds of early-onset hypertensive disorders of pregnancy, while fish intake during pregnancy showed different associations with late-onset disease, particularly among women who had not previously given birth. Total dietary omega-3 and omega-6 PUFA intake showed much less consistent associations, suggesting that the relationship with fish consumption may not be explained by total PUFA intake alone.

9 Sep 2026

Digital companion apps help secure long-term habits during GLP-1 therapy

Glucagon-like peptide-1 (GLP-1) medications have revolutionized weight management, yet high dropout rates and rapid weight regain remain significant hurdles for many patients.

9 Sep 2026

New study evaluates medical and surgical treatments for mitral regurgitation

Announcing a new article publication for Cardiovascular Innovations and Applications journal providing fresh evidence on the effectiveness of medical and surgical treatments for mitral regurgitation (MR).

9 Sep 2026

Single-cell atlas reveals key macrophage subtypes in myocardial infarction

Announcing a new article publication for BIO Integration. Myocardial infarction (MI) is characterized by extensive immune activation and dynamic remodeling of the cardiac microenvironment, in which myeloid cells play critical roles in regulating inflammation and tissue repair.

9 Sep 2026

New blood screening algorithm reduces unnecessary Alzheimer's PET scans

A new blood-based screening algorithm dramatically reduced the number of unnecessary PET scans needed to recruit patients at risk of Alzheimer's disease for a clinical trial, according to research from scientists at the Keck School of Medicine of USC published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

9 Sep 2026

Study shows how the microbiome shapes lung cancer immunotherapy outcomes

Despite the revolutionary impact of immune checkpoint inhibitors on cancer therapy, 60% to 80% of patients with NSCLC still show suboptimal responses.

9 Sep 2026