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Short-term immunosuppressive therapy briefly restores autism-like brain changes in adult mice

A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but also that those brain and behavior effects may be rapidly but temporarily reversible in adulthood with a short-term dose of the immunosuppressive drug rapamycin.

23 Jul 2026

Emerging PPAR therapies offer new hope for primary biliary cholangitis

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.

23 Jul 2026

Dormant melanocytes found in vitiligo offer hope for future repigmentation therapies

Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease.

23 Jul 2026

Ancient immune protein C3 boosts cancer immunotherapy within tumors

An ancient molecule that existed long before the blood circulation system evolved, has been found to support cancer immunotherapy.

23 Jul 2026

AI platform uncovers promising target for chronic pain treatmen

Despite the widespread availability of analgesics, pain management remains one of the most significant and pervasive challenges in modern medicine, with more than 20% of the global population suffering from chronic pain, especially chronic neuropathic pain characterized by central sensitization.

22 Jul 2026

Multiple sclerosis mortality trends underscore need for comprehensive patient care

An analysis of more than 42,000 U.S. deaths linked to multiple sclerosis (MS) found that death rates varied by age, geography, and race and ethnicity, with Black patients dying younger than white patients and high blood pressure emerging as a growing contributor.

22 Jul 2026

SuperAgers retain exceptional memory through mechanisms beyond genetics

Many people assume that some memory decline is an inevitable consequence of getting older. But a select group of older adults, known as SuperAgers, reach their 80s and 90s while retaining memory performance as good as or better than people in their 50s and 60s.

22 Jul 2026

Exercise may provide limited relief for hip osteoarthritis symptoms

Exercise finds improvements in pain and function may fall short of what patients would notice in daily life, but more studies are needed to make firm conclusions, a new Cochrane review finds.

22 Jul 2026

GLP-1 receptor agonists may increase hair loss risk

Use of glucagon-like peptide-1 (GLP-1) receptor agonists used to treat type 2 diabetes and obesity are associated with an increased risk of hair loss (alopecia) in adults with type 2 diabetes, finds a study published by The BMJ today.

22 Jul 2026

Plasma exchange improves recovery in rare inflammatory nerve disease

Plasma exchange can help treat people with a rare inflammatory disease that can cause blindness, according to a systematic review and meta-analysis published on July 22, 2026, in Neurology, the medical journal of the American Academy of Neurology.

22 Jul 2026

Multiple sclerosis deaths occur earlier among Black patients

Black people with multiple sclerosis (MS) die from MS at a younger age than white people, with a peak mortality rate at ages 65 to 74 for Black people and ages 75 to 84 for white people, according to a study published July 22, 2026, in Neurology® Open Access, an official journal of the American Academy of Neurology.

22 Jul 2026

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

22 Jul 2026

Motor abnormalities may predict multiple mental health disorders

Motor issues-such as coordination problems, motor slowing, or sudden, uncontrolled movements-have been recognized as signs of psychological disorders since the 1800s. How they map to mental health conditions, however, remains unknown.

22 Jul 2026

Racial and geographic disparities continue affecting stroke treatment outcomes

Three studies presented today at the Society of NeuroInterventional Surgery's (SNIS) 23rd Annual Meeting found that racial, geographic and socioeconomic disparities continue to influence stroke treatment and outcomes across the United States.

22 Jul 2026

Experimental neurointerventional technique shows promise for severe back pain

Researchers at the Society of NeuroInterventional Surgery (SNIS) 23rd Annual Meeting presented an experimental neurointerventional technique designed to treat severe back pain, a leading cause of disability and opioid use, by delivering medication directly through the arteries supplying the painful area.

22 Jul 2026

Gut immune cells may improve multiple sclerosis treatment outcomes

B-cell depletion therapies, in which B cells of the immune system, which may drive disease activity in multiple sclerosis (MS), are temporarily removed, have contributed significantly to improved treatment for patients in recent years.

22 Jul 2026

Mental health intervention reduces aggression and reoffending among violent offenders

Prisoners convicted of serious violent offences were found to be less aggressive and less likely to reoffend following a mental health intervention which could save money and reduce harm to society, according to new research led by King's College London.

22 Jul 2026

Former smokers retain lasting lung damage despite quitting

A new study by a team of McGill researchers could help explain why people who have quit smoking remain at elevated risk of lung disease long after their last cigarette.

22 Jul 2026

Urbanization reshapes gut microbiomes across diverse South Asian communities

Urbanization is one of the most consequential demographic shifts of the 21st century. As communities move from traditional or rural to urbanized ways of life, changes in diet, lifestyle, and environmental exposures can influence many aspects of human biology and health.

22 Jul 2026

Genetic background shapes cancer development despite identical risk factors

Why do cancers develop differently in different people-even when they are exposed to the same risk factors? An international research group, including the German Cancer Research Center (DKFZ), has now demonstrated in mice that an organism's genetic makeup significantly influences the course of cancer development.

22 Jul 2026