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CBL-514 injection reduces visceral and subcutaneous fat in trials

Details of a new injection that targets fat cells will be released at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

1 Oct 2026

Type 1 diabetes incidence rose by 11% after rotavirus vaccine rollout in Norway

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in Diabetologia (the journal of EASD) shows that incidence (the new case rate) of type 1 diabetes (T1D) in children aged 0.5-5 years in Norway was 11% higher following the rapid roll out and uptake of the rotavirus vaccine in September 2014.

1 Oct 2026

NIH-funded trials will test pregnenolone for addiction and depression

Center for BrainHealth investigator Francesca Filbey, PhD, and UTSW investigator Sherwood Brown, MD, PhD, have secured two awards from the National Institutes of Health (NIH) to fund two major collaborative studies investigating whether the naturally occurring neurosteroid pregnenolone can help treat substance use disorders and co-occurring depression.

1 Oct 2026

Stroke reshapes brain environment to accelerate glioma progression

After a stroke, the brain gets to work repairing damaged tissue. But new research suggests some of the same biological processes that aid recovery may also help tumor cells grow and spread.

1 Oct 2026

Spatial mapping reveals macrophage niches linked to severe COVID-19 lung injury

Researchers at the University of Liège have used imaging-based spatial single-cell transcriptomics to map the cellular organization of lungs from people who died with severe COVID-19.

1 Oct 2026

Varying mutation rates in healthy organs explain cancer risk

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

1 Oct 2026

Study links immune status to herpesvirus retinitis progression

The clinical progression and outcomes of two major herpesvirus retinitis forms are associated with patients' immune status, reveal Institute of Science Tokyo scientists.

1 Oct 2026

Gut bacterial metabolite worsens brain damage after stroke, study finds

Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after stroke.

1 Oct 2026

New framework maps depression symptoms to unique brain circuits

A research team from the Sant Pau Research Institute (IR Sant Pau) has published a scientific review proposing a paradigm shift in the way depression is understood and studied.

1 Oct 2026

New trial tests if diet can reduce bipolar depression symptoms

A clinical trial is set to test whether diet could help reduce depressive symptoms in people with bipolar disorder, comparing a high fat, low carbohydrate diet with standard NHS healthy eating advice.

1 Oct 2026

Mauritius becomes first country to reverse type 2 diabetes epidemic

New research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Diabetes & Endocrinology shows that the small island nation of Mauritius is the first country in the world to prove it is reversing the type 2 diabetes epidemic using the objective gold standard testing method of the 2-hour oral glucose tolerance test (2 hour OGTT).

1 Oct 2026

New study highlights heavy chewing tobacco burden in South Asia

A new study from the Institute for Health Metrics and Evaluation (IHME) finds that chewing tobacco use contributed to an estimated 251,000 deaths globally in 2023, with health loss overwhelmingly concentrated in South Asia.

1 Oct 2026

Oxford study identifies top technology priorities for respiratory care

Inhalers that show when they are running out. Oxygen equipment light enough to take out of the house. Help telling whether breathlessness is anxiety or the start of a flare-up.

1 Oct 2026

Trevogrumab cuts semaglutide-induced lean mass loss by half, study shows

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and in press with The Lancet shows that using the trevogrumab to inhibit myostatin, a protein that negatively regulates muscle mass, can reduce lean mass loss during treatment with semaglutide by 50% compared with semaglutide and placebo.

1 Oct 2026

Policy review demands better quality of life data in cancer clinical trials

A new policy review from Common Sense Oncology (CSO) and the European Organisation for Research and Treatment of Cancer (EORTC) calls for quality of life data to play a more central role in clinical trials evaluating adjuvant cancer treatments.

1 Oct 2026

Highlight Therapeutics presents positive Phase 2b topline results of intralesional BO‑112 in localized basal cell carcinoma as a late-breaker at EADV

Highlight Therapeutics, a clinical‑stage biotechnology company developing immune activators to transform the treatment of skin tumors, today announced positive results from the multicenter, single-arm Phase 2b SPOTLIGHT‑204 clinical trial evaluating BO‑112, a novel dsRNA-based intralesional treatment for patients with resectable primary low‑ and high‑risk basal cell carcinoma (BCC).

1 Oct 2026

Cognitive tests may not tell the whole story about memory concerns

This study highlights the link between blood biomarkers and dementia risk in subjective cognitive decline, emphasizing prevention and lifestyle changes.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Novel surgical technique restores clitoral sensation using buccal mucosa graft

For women who lose part of their clitoris because of vulvar cancer, a clitoral reconstruction procedure has now been developed for the first time. This comes forty years after the first penile reconstruction surgery. Results in the initial group of patients are encouraging.

1 Oct 2026

Real-world data reveals higher reported GLP-1 side effects in female patients

The second of a Series of papers presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Obstetrics, Gynaecology & Women's Health discusses the wide-ranging issues relating to use of GLP-1 RA drug use in women.

1 Oct 2026