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FDA approves atezolizumab combination for stage III colon cancer with deficient DNA mismatch repair

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has approved the immunotherapy drug atezolizumab (Tecentriq) in combination with fluoropyrimidine and oxaliplatin chemotherapy, for the adjuvant treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

9 Oct 2026

Study explains why cancer immunity declines faster in males

Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and Tim Padera, PhD, currently of the Mass General Brigham Cancer Institute, are the lead and senior authors of a paper published in Nature Aging, "Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age."

9 Oct 2026

Early-onset Alzheimer's patients accumulate symptoms years before diagnosis

People who develop Alzheimer's disease before the age of 65 experience a growing range of health problems and increasing use of healthcare services years before diagnosis.

9 Oct 2026

Lynch syndrome patients rarely use aspirin for cancer prevention

According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer - even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice.

9 Oct 2026

Brain injuries change how the hypothalamus responds to stress

Researchers from the Department of Cell Biology, Genetics and Physiology at the University of Malaga have led an international scientific team that has studied how a traumatic brain injury caused by a severe blow to the head conditions the brain's long-term response to subsequent stress situations.

9 Oct 2026

Body fat distribution may influence hunger hormones more than daily diet

Body fat distribution may reveal more about hunger hormones than recent diet.

9 Oct 2026

Gut bacteria may help explain why endometriosis pain varies

A study of 50 women with surgically confirmed endometriosis found that differences in gut bacterial composition were associated with menstrual pain, urinary symptoms, and infertility.

9 Oct 2026

Infections caused 1 in 8 cancer cases worldwide in 2024, study finds

Infections drove 1 in 8 cancer cases worldwide in 2024, study finds.

9 Oct 2026

US counties with more medical debt see higher rates of several late-stage cancers

Higher medical debt is linked to more late-stage cancer diagnoses across U.S. counties.

9 Oct 2026

What young cancer survivors revealed about stress, exercise and friendship

Adolescent and young adult cancer survivors use exercise and social support to cope with stress, revealing insights for effective mental health interventions.

9 Oct 2026

SPRED2 coordinates three signaling pathways to suppress liver cancer stemness

Liver cancer is the fifth most commonly diagnosed cancer and the second leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) accounts for 70-85% of primary liver cancers, and its five-year recurrence rate can reach 70-80%.

8 Oct 2026

Rare dendritic cells may promote immune tolerance in metastatic cancer

This study was co-led by Steven Blum, MD. Gary Reynolds, MD, PhD, Samuel Klempner, MD, and Alexandra-Chloé Villani, PhD, jointly supervised the work at the Krantz Family Center for Cancer Research within the Mass General Brigham Cancer Institute and the Mass General Brigham Center for Immunology & Inflammatory Diseases (CIID).

8 Oct 2026

Precise phenotyping improves genetic prediction of sensorineural hearing loss

A team of hearing specialists at Vanderbilt Health analyzed thousands of data samples in the institution’s BioVU biobank to understand genetic susceptibility of sensorineural hearing loss, which is caused by damage to the inner ear.

8 Oct 2026

Nicotinamide riboside fails to slow progression of early Parkinson’s disease

A major clinical trial involving 410 people with early Parkinson's disease has found no clinical benefit from nicotinamide riboside (NR), a compound that increases cellular levels of nicotinamide adenine dinucleotide (NAD). The findings are published in JAMA.

8 Oct 2026

Disrupted circadian rhythms may influence tumor immunity and cancer spread

Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal cancer.

8 Oct 2026

New framework aims to improve reliability of tear-based health sensors

Dr. Yangzhi Zhu of the Terasaki Institute for Biomedical Innovation (TIBI), with collaborators at UC San Diego and USC, published a Nature Sensors perspective on what it will take to turn tear-based wearable sensors into reliable, long-term health-tracking tools.

8 Oct 2026

Consuming fat before carbohydrates reduces post-meal blood glucose

In treating diabetes, post-meal elevation of glucose levels is an important therapeutic target. Existing clinical studies indicate that eating vegetables, protein, or fat before carbohydrates can moderate a post-meal rise in blood glucose, pointing to the potential of meal-sequencing as a simple and sustainable dietary strategy.

8 Oct 2026

NCCN collaborates with global organizations to launch tailored cancer guidelines for Philippines

The National Comprehensive Cancer Network (NCCN)-an alliance of leading academic cancer centers in the United States-is collaborating with several global organizations to publish new International Adaptations of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for the Philippines.

8 Oct 2026

Longer sleep duration linked to diabetic kidney disease risk

People with type 2 diabetes who sleep longer may have an increased risk of developing or worsening existing diabetic kidney disease, according to a study published in the Journal of the Endocrine Society.

8 Oct 2026

Expert consensus statement outlines shared medical appointments to improve chronic disease care

The American College of Lifestyle Medicine (ACLM) has published an expert consensus statement identifying best practices for delivering lifestyle interventions through shared medical appointments (SMAs), a care model that combines individualized medical care with group support.

8 Oct 2026