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Lysosomal protein stabilizes mitochondria to prevent severe heart failure

A new study published in Engineering has uncovered a regulatory mechanism linking lysosomal function to mitochondrial stability in pathological cardiac hypertrophy, identifying transient receptor potential mucolipin 1 (TRPML1) as a key protective factor against the progression to heart failure.

16 Jun 2026

Real-time brain stimulation improves gait for Parkinson's patients

UC San Francisco researchers have developed a new form of deep brain stimulation (DBS) that adjusts in real time as a person walks, helping improve gait and reduce falls in people with Parkinson's disease.

16 Jun 2026

Tirzepatide activates calorie-burning brown fat to combat obesity

Tirzepatide doesn't just help people lose weight; it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

16 Jun 2026

Novel embolization technique reduces pain from knee osteoarthritis

Embolization of abnormal blood vessels using rapidly resorbable gelatin-based microspheres is safe and provides significant, lasting pain relief and functional improvement for patients with osteoarthritis-related knee pain, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

16 Jun 2026

Depression shapes how children pay attention to emotional faces

A smile. A frown. The faces a child pays closer attention to might offer invaluable insight into their mental health.

16 Jun 2026

UVA neurologist investigates Medicare policy effects on stroke patients

After identifying significant differences in stroke care and outcomes for patients on different Medicare plans, a UVA Health doctor is launching an ambitious effort to better understand the sources of those differences and ensure patients get the best care possible.

16 Jun 2026

New biological ratio effectively predicts cardiovascular risk

Announcing a new article publication in BIO Integration. Insulin resistance (IR) and chronic kidney disease (CKD) are independent risk factors for cardiovascular disease (CVD).

16 Jun 2026

Prebiotic fiber supplement reduces harmful gut metabolites and improves liver health

A study conducted at the University of Jyväskylä, Finland, was the first to investigate the effects of prebiotic xylo-oligosaccharides (XOS) on fatty liver in humans.

16 Jun 2026

Machine learning identifies natural compound to treat lung disease

A new study published in Engineering has combined machine learning (ML) and experimental validation to identify dihydromyricetin (DHM), a natural flavonoid, as a potent inhibitor of the TGF-β/ALK5 signaling cascade with therapeutic potential for idiopathic pulmonary fibrosis (IPF).

16 Jun 2026

FutureNeuro launches proteomics study to personalize psychosis treatment

FutureNeuro, the Research Ireland Centre for Translational Brain Science hosted by RCSI University of Medicine and Health Sciences, has launched a new proteomics study aimed at identifying biological markers that could support more personalized treatment for people experiencing first‑episode psychosis.

16 Jun 2026

Study identifies top predictors for weight loss using tirzepatide

One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

16 Jun 2026

New USC clinical trial explores psilocybin for mental health

Researchers at the Keck School of Medicine of USC, the Brain and Creativity Institute at the USC Dornsife College of Letters, Arts and Sciences, and the USC Norris Comprehensive Cancer Center have launched the University of Southern California's first study of psychedelic therapy.

16 Jun 2026

Clinical trial data shows preserved beta-cell function key to new paradigms in diabetes care

Critical Path Institute® (C-Path), through its Type 1 Diabetes Consortium, today reaffirmed its commitment to strengthening the regulatory-science and evidence infrastructure needed to enable the next phase of therapeutic innovation across multiple stages of type 1 diabetes (T1D).

16 Jun 2026

Lab-grown cell models reveal urate triggers vital renal water channels

Mayo Clinic researchers have identified a previously unrecognized way the kidneys regulate water balance - an advance that could lead to improved treatments for polycystic kidney disease (PKD) and other disorders. The study, led by Fouad Chebib, M.D., a nephrologist at Mayo Clinic, is published in the Journal of Clinical Investigation.

16 Jun 2026

Prevention proves cheaper than treatment for Li-Fraumeni syndrome

Screening people with the rare, inherited cancer-causing condition Li-Fraumeni syndrome (LFS) brings both medical and economic benefits to patients and healthcare systems, according to research to be presented to the annual conference of the European Society of Human Genetics today (Tuesday).

15 Jun 2026

Study identifies genetic marker associated with severe IBD

In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker that is associated with more severe ulcerative colitis and Crohn's disease – the major forms of IBD.

15 Jun 2026

Migraine affects driving more often than clinicians may realize

A multicenter study of 1,333 active drivers with migraine found that 70.6% had experienced headache while driving, with headaches occurring during about 13% of driving sessions. The findings suggest that migraine-related symptoms may impair attention, increase sensitivity to road conditions, and contribute indirectly to driving cessation and accident risk.

15 Jun 2026

Persistent anxiety and depression may delay emotional maturity into midlife

A long-running Australian cohort study found that personality traits generally matured from early to middle adulthood, with agreeableness and conscientiousness rising and extraversion, openness, and neuroticism declining. People with persistent common mental disorders showed the clearest decline in neuroticism by midlife, but they still had higher emotional instability than peers without persistent mental health difficulties.

15 Jun 2026

Social media overuse is linked to more self-reported memory problems in young adults

Problematic social media use was associated with more frequent self-reported everyday memory failures in 943 Spanish young adults aged 18 to 35. Everyday memory failures statistically accounted for much of the link between problematic social media use and both prospective and retrospective memory lapses.

15 Jun 2026

Global study links rising obesity to premature heart disease deaths

Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people aged 50-54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2026