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Drug combination shows promise for treating aggressive T-cell lymphomas

Relapsed/refractory peripheral and cutaneous T-cell lymphomas (R/R PTCL and CTCL) are aggressive blood cancers that often resist standard therapy. Patients with these lymphomas may require stem cell transplants, but the disease needs to be brought under control before patients can undergo this treatment.

2 Jul 2025

Experimental medication sensitizes glioblastoma to treatment and blocks tumor spread

A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain cancer newly sensitive to both radiation and chemotherapy drugs, and blocks the cancer's ability to invade other tissue, a new study shows.

2 Jul 2025

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2 Jul 2025

Advancing treatment for urothelial cancer with enfortumab vedotin and pembrolizumab

A new review was published in Volume 16 of Oncotarget on June 17, 2025, titled "Optimizing enfortumab vedotin plus pembrolizumab therapy."

2 Jul 2025

Study enhances the understanding of urolithiasis pathogenesis

A recent study published in Genes & Diseases reveals new insights into the relationship between immune cell characteristics, blood metabolites, and the risk of urolithiasis.

2 Jul 2025

Timepoint at which B cells transform into leukemic cells impacts treatment outcomes

New findings show that the stage of normal cell development at which B cells transform into leukemic cells impacts treatment outcomes for pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL).

2 Jul 2025

Could your pregnancy diet shape your child’s immune future?

Researchers found that a pro-inflammatory maternal diet during pregnancy was linked to a 16% increased risk of type 1 diabetes in offspring. This large Danish cohort study suggests that maternal dietary patterns may shape long-term autoimmune risk in children.

2 Jul 2025

Is lactose intolerance secretly stealing your restful sleep?

Researchers surveyed over 1,000 university students and found that lactose intolerance, especially when accompanied by gastrointestinal symptoms, is linked to more frequent nightmares and poor sleep. Only a small minority reported that food affected their dreams, highlighting a specific risk for those with food sensitivities.

1 Jul 2025

Danish trial reveals how structured exercise and guidance affect life with chronic conditions

A large multicenter trial found that a 12-week personalized exercise therapy and self-management support program produced a small but statistically significant improvement in health-related quality of life for adults with multimorbidity. The intervention was safe, but its clinical relevance remains uncertain, as only self-rated health showed a significant benefit over usual care.

1 Jul 2025

Spaceflight exposes astronauts to hidden threats in their gut

This review highlights how the unique stressors of space travel, radiation, microgravity, and circadian disruption impact astronauts’ gut microbiomes, with potential consequences for their mood, cognition, and immunity. The authors call for targeted microbiome monitoring and dietary interventions to protect astronaut mental health on future missions.

1 Jul 2025

Long-term exposure to air pollution associated with early signs of heart damage

Researchers using cardiac MRI have found that long-term exposure to air pollution is associated with early signs of heart damage, according to a study that was published today in Radiology, a journal of the Radiological Society of North America (RSNA).

1 Jul 2025

Epilepsy self-management program shows promising results

Epilepsy is among the most common neurological conditions, marked by unpredictable seizures, accidents and injuries, reduced quality of life, stigma and-in the worst case-premature death.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Uterine cancer deaths expected to rise sharply in the United States by 2050

Uterine cancer incidence and mortality rates are projected to increase significantly over the next three decades in the United States, with incidence-based mortality expected to be nearly three times higher in Black women compared with white women by 2050.

1 Jul 2025

Oral drug MA-5 can improve heart and muscle problems in Barth syndrome

Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in Barth syndrome, a rare genetic disorder affecting 1 in 300,000 births worldwide with no current cure.

1 Jul 2025

Breakthrough study reveals killing power of CD4 T cells against cancer

In the fight against cancer, immunotherapy - which aims to boost the body's natural defences against cancer - is experiencing remarkable growth. Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells.

1 Jul 2025