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Driving behavior data may help detect early cognitive decline

Using in-vehicle driving data may be a new way to identify people who are at risk of cognitive decline, according to a study published on November 26, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Nov 2025

Experimental drug engasertib shows promise for treating inherited bleeding disorder

Hereditary hemorrhagic telangiectasia (HHT) is the second most common inherited bleeding disorder worldwide, affecting 1 in 3,800 persons.

26 Nov 2025

Researchers uncover key mechanism blocking nerve regeneration in diabetes

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve fibres do not regenerate sufficiently.

26 Nov 2025

Missing cancer gene may boost response to immunotherapy

For some patients with the most common type of lung cancer, known as lung adenocarcinoma, there's new hope.

26 Nov 2025

Study shows one in ten young cancer patients develop metastatic recurrence

A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in ten patients diagnosed with non-metastatic disease later develop metastatic recurrence - a condition associated with significantly worse survival outcomes.

26 Nov 2025

New 10-minute scan shows hidden cause of high blood pressure

A speedy new scan could improve how millions of people with high blood pressure are treated, suggests a new study led by UCL (University College London) researchers.

26 Nov 2025

Tai chi offers comparable benefits to CBT for chronic insomnia

Tai chi, a form of mind-body exercise widely practiced in Chinese communities, has similar benefits to talking therapy for middle aged and older people with chronic insomnia, finds a trial from Hong Kong published by The BMJ today.

26 Nov 2025

Monthly biologic injection improves severe asthma control and reduces steroid use

A monthly injection has helped 90% of severe asthma patients reduce daily steroid tablets, which are associated with long-term side effects.

26 Nov 2025

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

New study links inherited mitochondrial DNA mutation to disrupted immune balance

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death.

26 Nov 2025

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Shared genetic roots between delirium and Alzheimer’s disease

This study reveals genetic and proteomic risk factors for delirium, offering insights into its etiology and potential biomarkers for prediction and prevention.

26 Nov 2025

Head trauma impairs brain waste clearance in professional fighters

The brain's waste-clearing system significantly declines in function with repeated head impacts, according to a new study of cognitively impaired professional boxers and mixed martial arts fighters. The findings will be presented next week at the annual meeting of the Radiological Society of North America.

26 Nov 2025

SISAQOL-IMI provides guidance for implementing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organisation for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), just announced the publication of its pivotal paper in The Lancet Oncology outlining how its recommendations for patient-reported outcomes (PROs) in cancer clinical trials were developed.

26 Nov 2025

Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

EACVI 2025 brings cardiac imaging experts together in Vienna

The European Association of Cardiovascular Imaging (EACVI), a branch of the European Society of Cardiology (ESC), will hold its flagship event, EACVI 2025, in Vienna, Austria from 11-13 December.

26 Nov 2025

Dysfunctional breathing is common and influenced by tobacco use and respiratory conditions

Dysfunctional breathing (DB) is frequently misdiagnosed or insufficiently treated, leading to a diminished quality of life and unnecessary medical intervention.

25 Nov 2025

Poor lung gas exchange may help explain lingering brain symptoms in Long COVID

This study found that people with Long COVID more than two years after infection showed normal lung tests and brain structure, yet reported significant sleep and cognitive symptoms. Subtle correlations revealed that poorer lung gas exchange was linked with higher brain perfusion, worse sleep, and weaker executive function, suggesting a possible lung–brain connection.

25 Nov 2025

Moderate coffee intake linked to slower biological aging in people with severe mental illness

Drinking a maximum of 3-4 cups of coffee a day may slow the 'biological' ageing of people with severe mental illness, by lengthening their telomeres-indicators of cellular ageing-and giving them the equivalent of 5 extra biological years, compared with non-coffee drinkers, finds research published in the open access journal BMJ Mental Health.

25 Nov 2025

AI-powered tool improves object detection for visually impaired users

Over the last few years, systems and applications that help visually impaired people navigate their environment have undergone rapid development, but still have room to grow, according to a team of researchers at Penn State.

25 Nov 2025