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Guselkumab shows minor added benefit for specific Crohn's disease patients

The human monoclonal antibody guselkumab has been approved for certain adults with moderately to severely active ulcerative colitis since April 2025.

27 Mar 2026

LDCT screening significantly reduces lung cancer mortality in non-smokers

New evidence from a Chinese cohort presented today at the European Lung Cancer Congress (ELCC) 2026 shows that onetime lowdose computed tomography (LDCT) screening can significantly reduce lung cancer mortality in a non-risk based population, including individuals with no smoking history.

27 Mar 2026

Molecular test shows high sensitivity in detecting bile duct cancer

When patients develop a narrowing or blockage in the bile ducts – the tubes connecting the liver, gallbladder and intestines – physicians must determine whether the cause is cancer or a benign condition.

27 Mar 2026

Drugs targeting TIE2 protein could help prevent formation of cerebral cavernous malformations

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of blood vessel abnormalities known as cerebral cavernous malformations (CCMs).

27 Mar 2026

Updated heart guidelines urge earlier screening for high blood cholesterol

For the first time since 2018, a clinical guideline from the American College of Cardiology and the American Heart Association for screening and managing blood cholesterol levels has been updated and jointly published in the Journal of the American College of Cardiology and Circulation.

27 Mar 2026

Early testosterone surge triggers rare muscle disease

Spinal and Bulbar Muscular Atrophy (SBMA) is a rare inherited disease that causes progressive muscle weakness and wasting in men.

27 Mar 2026

Liposomal nanotechnology enhances precision and efficacy in photodynamic cancer therapy

Photodynamic therapy (PDT) uses light to activate special drugs called photosensitizers to destroy cancer cells with high precision.

27 Mar 2026

Hospital delirium associated with increased likelihood of future dementia

Older adults who develop delirium during a hospital admission face a substantially higher risk of dementia in later years, even if they had no prior health conditions, according to a major new population study.

27 Mar 2026

Dandelion leaves boost brain-protective compounds after digestion

Dandelion leaves are rich in polyphenols with neuroprotective effects, offering insights into natural strategies for Alzheimer's disease management.

27 Mar 2026

New initiative aims to scale individualized therapies for rare diseases

Critical Path Institute (C-Path) today announced the launch of One to Millions, a global, multi-stakeholder public-private initiative to enable scalable development of advanced therapies for highly individualized conditions.

26 Mar 2026

Machine learning model predicts liver cancer risk with high accuracy

A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient's risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high accuracy.

26 Mar 2026

Study reveals overlooked depression symptoms in South Asian communities

Physical pain, heart-related sensations and repetitive negative thinking are among the most commonly reported symptoms of depression in South Asian communities - yet none appear in the diagnostic criteria used to screen for depressive disorders in the UK, according to a new review led by the University of Surrey.

26 Mar 2026

Attachment anxiety linked to higher risk of short video addiction

No matter where we turn on social media, short videos are everywhere. Repeated exposure to this brief, information-dense, and rewarding content stimulates the brain in a way that tells us the experience is pleasurable or satisfying.

26 Mar 2026

Microfluidic chips enable realistic modeling of tumor immune environments

The challenge is that the tumor immune microenvironment is not a static backdrop but a constantly shifting ecosystem shaped by cancer cells, immune cells, stromal cells, cytokines, and physical barriers.

26 Mar 2026

Study explores racial differences in gastric cancer immunotherapy outcomes

Advanced gastric cancer remains one of the deadliest malignancies, with a 5-year overall survival rate below 10%.

26 Mar 2026

New algorithm enables precise subtyping of metabolic liver disease

Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30% individuals globally.

26 Mar 2026

High-intensity therapy early after stroke shows no added benefit

A clinical trial led by University of Auckland researchers found that high-intensity therapy for patients begun within two weeks of a stroke did not improve hand and arm recovery beyond standard care.

26 Mar 2026

Heart failure and atrial fibrillation share underlying genetic and molecular mechanisms

New research published in Nature Cardiovascular Research reveals that heart failure and atrial fibrillation share underlying genetic and molecular mechanisms, suggesting that the two cardiovascular conditions may be less distinct than previously thought.

26 Mar 2026

Study reveals how inflammation disrupts lymph node structure in lymphoma

In aggressive lymphomas, inflammatory messengers reprogram the "conductors" of the immune system, causing lymph nodes structure to collapse.

26 Mar 2026

ATLAS platform enables realistic study of metastatic cancer clusters

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

26 Mar 2026