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Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

A single 25-mg dose of psilocybin with psychological support was feasible to deliver within an NHS setting and produced large preliminary reductions in depressive symptoms among adults with treatment-resistant depression. The Phase 2 feasibility trial also found the treatment was generally well tolerated, although functional unblinding and expectancy effects mean larger, longer efficacy studies are needed.

10 Aug 2026

New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Explainable AI helps predict dangerous bleeding after severe heart attacks

Researchers at Indiana University School of Medicine have developed and tested a six-point scoring system that can help identify patients at high risk of internal bleeding in damaged heart muscle after a severe heart attack using explainable artificial intelligence (XAI).

9 Aug 2026

Integrated nanomaterials offer new strategies for cancer immunotherapy

Immune checkpoint inhibitors, cancer vaccines and cellular therapies have reshaped oncology, yet most patients still do not achieve lasting benefit.

9 Aug 2026

Single-use endoscope aims to improve gastric cancer screening

Gastric cancer screening in Japan still relies heavily on double-contrast X-ray imaging, commonly known as the barium test.

9 Aug 2026

Study uncovers molecular trigger behind pyrin inflammation in familial Mediterranean fever

Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation.

7 Aug 2026

Thinning cancer cells' sugar coating could expose tumors to immune attack

Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat of sugar-derived molecules that throws the proverbial hounds of our immune systems off the scent.

7 Aug 2026

Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma

The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent key drivers of hepatocellular carcinoma (HCC) progression. mTOR-mediated ferroptosis suppression has been implicated in HCC resistance to chemotherapy.

7 Aug 2026

Researchers find a new genetic vulnerability in acute myeloid leukemia

A study published in Nature Cell Biology reports a new vulnerability in acute myeloid leukemia (AML) that might lead to novel therapies to treat this cancer while minimizing harm to normal cells.

7 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

New review explores purinergic signaling pathways in osteoarthritis progression

A growing understanding of purinergic signaling is reshaping how scientists view osteoarthritis (OA), revealing an intricate communication network that influences joint inflammation, cartilage degeneration, bone remodeling, and chronic pain.

7 Aug 2026

Living near a dry cleaner may come with an unexpected Parkinson’s disease link

A nationwide case-control study of older U.S. Medicare beneficiaries found that living closer to a dry-cleaning establishment was associated with higher odds of incident Parkinson’s disease, with the strongest association among people living within 0.1 mile.

7 Aug 2026

Researchers discover smart molecular glue that activates inside oxidative cancer cells

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

7 Aug 2026

Fine particle pollution raises rheumatoid arthritis flare risk and disease activity

Higher ambient PM2.5 exposure was associated with increased rheumatoid arthritis disease activity and a greater likelihood of flares in a four-year South Korean cohort of 1,070 patients. The association appeared stronger with sustained exposure over approximately two weeks or longer, while women and nonsmokers showed more pronounced links between PM2.5 and DAS28-CRP.

7 Aug 2026

Metabolic stress triggers long-lasting immune system changes in diabetes patients

A growing understanding of trained immunity, a form of long-lasting immune system adaptation, is reshaping how scientists view diabetes and its many complications.

7 Aug 2026

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

7 Aug 2026

Medical Condition News

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

New drug delivers promising survival gains in pancreatic cancer

Explainable AI helps predict dangerous bleeding after severe heart attacks

Integrated nanomaterials offer new strategies for cancer immunotherapy

Single-use endoscope aims to improve gastric cancer screening

Study uncovers molecular trigger behind pyrin inflammation in familial Mediterranean fever

Thinning cancer cells' sugar coating could expose tumors to immune attack

Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma

Researchers find a new genetic vulnerability in acute myeloid leukemia

Piezo ion channels: Key regulators of digestive health and disease

New review explores purinergic signaling pathways in osteoarthritis progression

Living near a dry cleaner may come with an unexpected Parkinson’s disease link

Researchers discover smart molecular glue that activates inside oxidative cancer cells

Fine particle pollution raises rheumatoid arthritis flare risk and disease activity

Metabolic stress triggers long-lasting immune system changes in diabetes patients

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Autophagy modulation emerges as a strategy against cisplatin-resistant gastric cancer

D-serine promotes gastric cancer growth by suppressing tumor immunity

AI detects multiple heart failure types from routine ECGs

New study reveals genetic drivers of inherited bone marrow failure syndrome

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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