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American Heart Association warns of growing health care cost crisis

With health care costs constituting a major source of concern across the U.S., the American Heart Association, a relentless force changing the future of health for everyone, everywhere, today released a Presidential Advisory warning that health care affordability in this country has reached crisis levels and outlining key principles to address the problem.

30 Apr 2026

Impaired protein recycling drives T cell exhaustion in cancer

T cells are crucial components of our immune system, serving as critical protectors against infection and disease.

30 Apr 2026

Pretargeted radioimmunotherapy shows promise for colorectal cancer treatment

A new pretargeted radioimmunotherapy (PRIT) technique has been shown to be safe and effective in eradicating tumors from a preclinical colorectal cancer model.

30 Apr 2026

Retrieval-augmented AI improves accuracy in cancer care tools

Artificial intelligence tools like ChatGPT are increasingly being explored in cancer care, but they can sometimes produce outdated or incorrect information. In medicine, where accuracy is critical, that risk is a serious concern.

30 Apr 2026

Extracellular vesicles from T cells enhance tumor immune response

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine.

30 Apr 2026

New CAR T cell design boosts persistence and reduces toxicity

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

30 Apr 2026

Study reveals new immune mechanism behind mevalonate kinase deficiency

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder.

30 Apr 2026

T1GRS model enhances prediction of genetic risk for Type 1 diabetes

In people with Type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy.

30 Apr 2026

Brain blips in epilepsy can be predicted before onset

Epilepsy is best known for seizures, but many people with the condition also experience much more frequent and subtler disruptions.

30 Apr 2026

New screening tool predicts health risks for people living with obesity

A simple tool, developed by researchers at Queen Mary University of London and the Berlin Institute of Health at Charité, could help identify which people living with obesity or overweight are most likely to develop serious obesity-related conditions such as type 2 diabetes and heart disease.

30 Apr 2026

Degeneration in two brain regions causes severe narcolepsy symptoms

For nearly 25 years, scientists believed they knew what caused the most severe form of narcolepsy. A new UCLA Health study now suggests they were only half correct.

30 Apr 2026

Scientists discover a potential new way to slow ALS disease progression

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which in most cases leads to respiratory failure within three to five years after diagnosis.

30 Apr 2026

Inflammation from leaking mitochondria drives aggressive pancreatic cancer growth

Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be targeted as a potential therapy.

30 Apr 2026

Climate change increases stroke risk through extreme weather and pollution

The World Stroke Organization is warning that climate change poses an escalating threat to brain health, with extreme heat in particular increasing the risk of having a stroke and of patients dying from stroke.

30 Apr 2026

New initiative aims to tackle bronchiectasis underdiagnosis in America

The American Thoracic Society (ATS) today announced a major quality improvement initiative aimed at tackling the persistent and widespread underdiagnosis of bronchiectasis in the United States.

30 Apr 2026

New research shows weight loss is possible without GLP-1

Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.

30 Apr 2026

Maternal screening could help prevent deadly forms of leukemia

A deadly form of leukemia may be stopped before it ever develops by introducing targeted maternal screening in the United States, according to new research.

30 Apr 2026

Antibiotic minocycline shows potential for treating panic disorder symptoms

A study supported by FAPESP shows that small doses of the antibiotic minocycline may help treat panic disorder.

30 Apr 2026

From killers to strategists: CAR T cells enter their multifunctional era

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

30 Apr 2026

Survey reveals silica dust risks for Australia’s tunnel workers

The responses to a national survey published today have revealed tunnel construction workers across Australia say they face significant exposure to silica dust, a hazardous dust that can cause incurable diseases like silicosis and lung cancer.

29 Apr 2026