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Semaglutide slows blood protein signature linked to future dementia risk

A post hoc analysis of 2,970 older SELECT participants found that semaglutide slowed worsening of a 25-protein blood signature that predicts future dementia risk. Over 104 weeks, semaglutide produced larger effects on modeled 5-year than 20-year dementia risk, but whether these biomarker changes translate into less cognitive decline or dementia remains unknown.

10 Aug 2026

Faith-based screenings expand early dementia detection among African Americans

Alter Dementia, Dementia Care Aware (DCA) and SageNavigator facilitated more than 100 free, community-based cognitive screenings at the 2026 Alter Dementia Summit and Aging Well Expo in Atlanta, Georgia, for the 100 Minds Screening Project.

10 Aug 2026

Study identifies key immune cell changes in the lungs of people with sarcoidosis

Researchers at National Jewish Health and partner institutions discovered specific changes in immune cells in the lungs of people with sarcoidosis.

10 Aug 2026

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

A new research paper was published in Volume 17 of Oncotarget on August 7, 2026, titled "Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers."

10 Aug 2026

New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes

Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the stem cells that drive high-risk myelodysplastic syndromes (MDS), a discovery that could lead to more targeted treatments for this aggressive blood cancer.

10 Aug 2026

New protein blueprint opens door for targeted Parkinson's disease therapies

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

10 Aug 2026

New gene signature predicts immunotherapy success for bone marrow cancers

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

Scientific statement reframes cardiovascular care for older patients with cognitive impairment and frailty

Older adults with cardiovascular disease (CVD) often have coexisting cognitive impairment and frailty, conditions that can significantly affect treatment decisions, recovery, independence and quality of life and should be considered as part of an aging-informed approach to care, according to a new American College of Cardiology Scientific Statement published in JACC, the flagship journal of the ACC.

10 Aug 2026

Immune cell interaction timing impacts glioblastoma treatment response

A joint research team led by Professor Sungsu Park of Sungkyunkwan University and Professor Sun-Ha Paek of Seoul National University College of Medicine has demonstrated for the first time that the sequence in which immune cells interact with cancer cells can critically influence the therapeutic response in glioblastoma.

10 Aug 2026

New report shows rising job search among disabled individuals

More people with disabilities were actively looking for work in July compared to June, while the number of people without disabilities seeking employment declined over the same period.

10 Aug 2026

Newly discovered protein pathway limits spinal cord injury damage

Spinal cord injury begins with immediate mechanical damage, but much of the lasting neurological loss develops during the secondary phase, when inflammation, oxidative stress and disrupted metabolism continue to injure surviving tissue.

10 Aug 2026

Circular eccDNA shows potential to predict early-stage LUAD recurrence

LUAD is the most common histological subtype of lung cancer. Although surgery can be curative for patients diagnosed at an early stage, approximately 30%-50% develop recurrence or aggressive metastasis within five years.

10 Aug 2026

Fridge-free vaccine shows promise for reaching millions more people worldwide

The world-first trial of a fridge-free tetanus-diphtheria vaccine at University Hospital Southampton (UHS) has produced encouraging results that could improve access worldwide to crucial treatments.

10 Aug 2026

Tirzepatide lowers heart attack and cardiovascular event risk in adults with type 2 diabetes

In a US cohort of 52,971 adults with type 2 diabetes and established atherosclerotic cardiovascular disease, tirzepatide initiation was associated with a lower one-year risk of major adverse cardiovascular events than sitagliptin. The benefit was driven mainly by lower myocardial infarction and all-cause mortality hazards, although the authors cautioned that mortality findings may be influenced by residual confounding.

10 Aug 2026

Study links better midlife vascular health to nearly 13 more dementia-free years

A long-term study of 12,409 adults found that a greater burden of diabetes, hypertension, and current smoking in midlife was associated with substantially fewer years lived free of dementia. Adults with none of these risk factors had about 30.1 dementia-free years from age 55, compared with 17.5 years among those with all three, a difference of nearly 13 years.

10 Aug 2026

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

A single 25-mg dose of psilocybin with psychological support was feasible to deliver within an NHS setting and produced large preliminary reductions in depressive symptoms among adults with treatment-resistant depression. The Phase 2 feasibility trial also found the treatment was generally well tolerated, although functional unblinding and expectancy effects mean larger, longer efficacy studies are needed.

10 Aug 2026

New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Explainable AI helps predict dangerous bleeding after severe heart attacks

Researchers at Indiana University School of Medicine have developed and tested a six-point scoring system that can help identify patients at high risk of internal bleeding in damaged heart muscle after a severe heart attack using explainable artificial intelligence (XAI).

9 Aug 2026

Integrated nanomaterials offer new strategies for cancer immunotherapy

Immune checkpoint inhibitors, cancer vaccines and cellular therapies have reshaped oncology, yet most patients still do not achieve lasting benefit.

9 Aug 2026

Single-use endoscope aims to improve gastric cancer screening

Gastric cancer screening in Japan still relies heavily on double-contrast X-ray imaging, commonly known as the barium test.

9 Aug 2026

Medical Condition News

Semaglutide slows blood protein signature linked to future dementia risk

Faith-based screenings expand early dementia detection among African Americans

Study identifies key immune cell changes in the lungs of people with sarcoidosis

Study links delayed Ewing sarcoma growth to reduced Trk and IGF1R pathway markers

New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes

New protein blueprint opens door for targeted Parkinson's disease therapies

New gene signature predicts immunotherapy success for bone marrow cancers

Scientific statement reframes cardiovascular care for older patients with cognitive impairment and frailty

Immune cell interaction timing impacts glioblastoma treatment response

New report shows rising job search among disabled individuals

Newly discovered protein pathway limits spinal cord injury damage

Circular eccDNA shows potential to predict early-stage LUAD recurrence

Fridge-free vaccine shows promise for reaching millions more people worldwide

Tirzepatide lowers heart attack and cardiovascular event risk in adults with type 2 diabetes

Study links better midlife vascular health to nearly 13 more dementia-free years

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

New drug delivers promising survival gains in pancreatic cancer

Explainable AI helps predict dangerous bleeding after severe heart attacks

Integrated nanomaterials offer new strategies for cancer immunotherapy

Single-use endoscope aims to improve gastric cancer screening

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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