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Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Glioblastoma (GBM), the most aggressive primary brain tumor, continues to portend a poor prognosis with median survival under two years, despite standard care involving surgery, radiation, and temozolomide chemotherapy.

30 Oct 2025

Scientists uncover why many cancer patients develop chemotherapy-induced neuropathy

Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why many cancer patients develop nerve damage after chemotherapy.

30 Oct 2025

Breakthrough could offer a new therapeutic option for stopping diabetes-induced complications

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

30 Oct 2025

Veterans with post-traumatic brain injury epilepsy more likely to have higher mortality rates

Military veterans who develop epilepsy after a traumatic brain injury may have a higher mortality rate in the following years than veterans who develop epilepsy with no previous traumatic brain injury, according to a study published on October 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

30 Oct 2025

New study sheds light on vision loss in idiopathic intracranial hypertension

If untreated, a disorder of high brain pressure called idiopathic intracranial hypertension can lead to vision loss. But this disorder can develop without noticeable symptoms, making it hard to catch.

30 Oct 2025

Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are associated with psychiatric disorders, such as depression, schizophrenia, and bipolar disorder.

30 Oct 2025

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

Stem cells show promise in preventing post-heart attack heart failure

Patients with weak heart function who receive stem cell therapy shortly after a heart attack are at lower risk of developing heart failure and related hospital stays compared with standard care, finds a clinical trial published by The BMJ today.

30 Oct 2025

WHO reviews highlight limited long-term data on GLP-1 drug safety

Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform upcoming guidelines on the use of these drugs to treat obesity.

30 Oct 2025

Diets that harm the planet also raise the risk of cancer, heart disease, and diabetes

Diets that place greater pressure on the environment, high in meat and low in plant foods, were linked to higher risks of cancer, coronary heart disease, and type 2 diabetes in over 34,000 French adults. Sustainable, plant-rich diets were associated with better health and lower environmental impact.

29 Oct 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025

Eating habits tied to Parkinson’s risk: sweets and processed meats raise odds, fruit lowers them

In a large Italian case-control study, researchers identified data-driven dietary patterns linked to Parkinson’s disease risk. Diets rich in sweets, red and cured meats were associated with higher odds of PD, while fruit, especially citrus, was protective.

29 Oct 2025

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to help answer how type 1 diabetes manifests and develop potential therapeutics to reverse or prevent the disease.

29 Oct 2025

Rapamycin shows promise in treating cold tumors with specific gene mutation

Immune checkpoint inhibitors (ICIs) emerged in the US about 15 years ago as an exciting class of cancer treatments that have achieved complete and durable remissions for thousands of people with end-stage metastatic cancers.

29 Oct 2025

Targeting myeloid cells to enhance cancer immunotherapy

Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard immunotherapies for cancer.

29 Oct 2025

Computational model predicts the hemodynamic response of patients following atrial fibrillation

Atrial fibrillation (AFib) is a cardiac disorder in which the chambers of the heart beat rapidly and irregularly. It's the most common type of arrhythmia and the leading cardiac cause of stroke.

29 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Harnessing extracellular vesicles for targeted lung cancer treatment

In the quest for more targeted lung cancer treatments, a researcher at the University of Missouri thinks the solution may lie in tiny bubble-shaped packages that cells use to talk to each other.

29 Oct 2025

Study sheds light on the practice patterns of aerosol drug therapy in patients with ARDS

A new review led by Associate Professor Sanjay Singhal from Dr. Ram Manohar Lohia Institute of Medical Sciences sheds light on the prevalence and practice patterns of ADT in patients with ARDS.

29 Oct 2025

Medical Condition News

Fundamental challenges and cutting-edge strategies in developing new GBM CAR-T therapies

Scientists uncover why many cancer patients develop chemotherapy-induced neuropathy

Breakthrough could offer a new therapeutic option for stopping diabetes-induced complications

Veterans with post-traumatic brain injury epilepsy more likely to have higher mortality rates

New study sheds light on vision loss in idiopathic intracranial hypertension

Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Stem cells show promise in preventing post-heart attack heart failure

WHO reviews highlight limited long-term data on GLP-1 drug safety

Diets that harm the planet also raise the risk of cancer, heart disease, and diabetes

Diabetes remission possible with GLP-1 drugs, Italian study confirms

Eating habits tied to Parkinson’s risk: sweets and processed meats raise odds, fruit lowers them

Aligning your body clock may protect your heart and metabolism, says AHA

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Rapamycin shows promise in treating cold tumors with specific gene mutation

Targeting myeloid cells to enhance cancer immunotherapy

Computational model predicts the hemodynamic response of patients following atrial fibrillation

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

Harnessing extracellular vesicles for targeted lung cancer treatment

Study sheds light on the practice patterns of aerosol drug therapy in patients with ARDS

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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