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Super agers' resilience against Alzheimer's disease linked to protective gene variant

The gene variant posing the greatest genetic risk of late-onset Alzheimer's disease (AD) is called APOE-ε4. A different variant of the same gene, APOE-ε2, is thought to confer protection against AD.

19 Jan 2026

New study exposes a targetable vulnerability in acute myeloid leukemia

New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia by identifying the blood cancer's reliance on a specific signaling pathway involved in the body's inflammation response.

19 Jan 2026

Novel method predicts asthma exacerbations with high degree of accuracy

Researchers at Mass General Brigham and Karolinska Institutet have identified a new method to predict asthma exacerbations with a high degree of accuracy. The study is published in Nature Communications.

19 Jan 2026

Wearable device enables natural speech in stroke patients with dysarthria

Researchers have developed a wearable, comfortable and washable device called Revoice that could help people regain the ability to communicate naturally and fluently following a stroke, without the need for invasive brain implants.

19 Jan 2026

Research suggests bamboo-based foods could support metabolic health

This systematic review synthesizes human, in vitro, and food-processing studies on bamboo consumption, finding limited but suggestive evidence for metabolic, digestive, and antioxidant benefits when products are properly prepared. It also highlights safety considerations, including potential goitrogenic effects from inadequately processed shoots, and calls for higher-quality human trials.

18 Jan 2026

Pulse oximeters miss hypoxemia more often in people with darker skin, study finds

This large prospective UK study compared five low-cost fingertip pulse oximeters with arterial blood gas measurements and found that readings varied systematically by skin tone and oxygen saturation level. Small average overestimations in darker skin translated into clinically meaningful increases in missed hypoxemia at commonly used SpO2 thresholds.

18 Jan 2026

Blood metabolites reveal who will develop type 2 diabetes years before diagnosis

This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention.

18 Jan 2026

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

Women and anxious people show distinct types of underconfidence

Women and people with anxiety are both prone to low confidence in their own abilities, but a new study by University College London (UCL) researchers has found that the two groups are prone to two distinct types of underconfidence.

16 Jan 2026

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

16 Jan 2026

Study reveals how ketogenic diet protects against epilepsy seizures

University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy seizures and possibly neurodegenerative diseases such as Alzheimer's and Parkinson's.

16 Jan 2026

Majority of older adults in Ireland have poorly controlled high blood pressure

High blood pressure becomes more common after age 40years yet new research from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin shows that many people in Ireland with hypertension are still not optimally diagnosed or treated based on European Gudelines.

16 Jan 2026

Study finds growing long-term antipsychotic prescribing in elderly dementia patients

When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people.

16 Jan 2026

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and immune checkpoint inhibitor drugs, but it's not always clear which therapy is inducing what type of response.

16 Jan 2026

Alternative splicing of DOC2A gene shown to drive schizophrenia risk

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.

16 Jan 2026

Purdue-developed LENN system enhances stability and targeting of mRNA cancer therapies

Published, peer-reviewed research shows a patent-pending, virus-mimicking platform technology developed at Purdue University improves upon traditional methods of targeting bladder cancer cells with messenger RNA (mRNA) therapies.

16 Jan 2026

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anderson Cancer Center.

16 Jan 2026

Age-related sperm changes at imprint regions linked to autism risk

A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled "Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring."

16 Jan 2026

Targeting microRNA communication reverses pancreatic cancer's immune suppression

In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor.

16 Jan 2026

Shifting blame: Public opinion on opioid crisis responsibility divides along political lines

Approximately 88% of adults view opioid overdose deaths as a very serious problem with high agreement across political groups, according to a national survey conducted by Weill Cornell Medicine researchers.

16 Jan 2026

Medical Condition News

Super agers' resilience against Alzheimer's disease linked to protective gene variant

New study exposes a targetable vulnerability in acute myeloid leukemia

Novel method predicts asthma exacerbations with high degree of accuracy

Wearable device enables natural speech in stroke patients with dysarthria

Research suggests bamboo-based foods could support metabolic health

Pulse oximeters miss hypoxemia more often in people with darker skin, study finds

Blood metabolites reveal who will develop type 2 diabetes years before diagnosis

Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts

Women and anxious people show distinct types of underconfidence

Single-cell technique maps pre-malignant gene mutations in solid tissues

Study reveals how ketogenic diet protects against epilepsy seizures

Majority of older adults in Ireland have poorly controlled high blood pressure

Study finds growing long-term antipsychotic prescribing in elderly dementia patients

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Alternative splicing of DOC2A gene shown to drive schizophrenia risk

Purdue-developed LENN system enhances stability and targeting of mRNA cancer therapies

Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome

Age-related sperm changes at imprint regions linked to autism risk

Targeting microRNA communication reverses pancreatic cancer's immune suppression

Shifting blame: Public opinion on opioid crisis responsibility divides along political lines

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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