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Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Does coffee truly boost memory and focus or is it all hype?

Coffee’s bioactive compounds, especially caffeine, show potential cognitive, neuroprotective, and neuroplasticity benefits across animal and human studies. However, most findings are observational, mechanisms remain uncertain, and optimal intake is still unclear.

23 Nov 2025

Masturbation could improve mood and sleep during menopause

This study found that about one in five perimenopausal and postmenopausal women experienced measurable symptom relief from masturbation, particularly for sleep and mood. Nearly half said they would consider using it for symptom relief if their doctor recommended it, although many had never discussed it with a clinician.

23 Nov 2025

American Heart Association honors schools and students for fighting childhood obesity

One in every five American children and teens is obese; that's up 35% from 2000, as severe childhood obesity rates have nearly doubled in that time.

22 Nov 2025

Intranasal nanomedicine shows promise against glioblastoma

Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers.

22 Nov 2025

Experts launch digital hub to transform bowel cancer prevention and care

World-leading experts have launched an online platform to enable the public to shape the future of bowel cancer research and patient care.

22 Nov 2025

New clues in pancreas lymph nodes, spleen could help detect and prevent type 1 diabetes

Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have it, most of the body's insulin-producing cells are destroyed.

22 Nov 2025

Study highlights limitations of current cardiac screening tools

Current cardiac screening tools used to prevent heart attacks fail to identify nearly half of the people who are actually at risk of having one, according to a new study led by Mount Sinai researchers.

22 Nov 2025

ASHG to host Genetic Diagnosis & Rare Disease Virtual Symposium

The American Society of Human Genetics (ASHG) will host the Genetic Diagnosis & Rare Disease Virtual Symposium on December 2-3. This initiative ensures that groundbreaking research and clinical innovations are accessible to scientists, clinicians, and educators.

22 Nov 2025

World’s first experimental lung cancer vaccine to enter clinical trials

People at high risk of lung cancer will soon be able to receive the first ever experimental vaccine designed to prevent the disease, in a world-first clinical trial led by researchers at UCL and the University of Oxford.

22 Nov 2025

What to know about the CDC’s baseless new guidance on autism

The rewriting of a page on the CDC's website to assert the false claim that vaccines may cause autism sparked a torrent of anger and anguish from doctors, scientists, and parents who say Health and Human Services Secretary Robert F. Kennedy Jr. is wrecking the credibility of an agency they've long relied on for unbiased scientific evidence.

22 Nov 2025

Study offers new insights on patient care and lung cancer surveillance rates

Despite recommendations for posttreatment surveillance in lung cancer patients, there is wide variability in the follow-up care that lung cancer patients receive. A recent study, led by senior author Leah Backhus, MD, MPH, Professor of Cardiothoracic Surgery (Thoracic Surgery) in the Stanford Department of Cardiothoracic Surgery, offers new insights on patient care and lung cancer surveillance rates.

21 Nov 2025

Inflammation control can protect against AMD-like retinal damage

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models.

21 Nov 2025

New trial to test extended tranexamic acid use for faster ACL surgery recovery

A breakthrough could be coming in the way young people recover from surgery to reconstruct the anterior cruciate ligament (ACL) in the knee, a common sports injury.

21 Nov 2025

Discovery of unexpected mechanism may help improve healing across muscle injuries

At the cellular level, the mechanics of how muscle tissue repair occurs gets complicated. There are significant differences between, say, tearing a muscle in a sports injury versus muscle tissue wasting away from diseases like muscular dystrophy.

21 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Study finds early neural markers of addiction risk differ between boys and girls

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine.

21 Nov 2025

Oral arginine reduces amyloid buildup in Alzheimer’s models

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their clinical effectiveness remains limited.

21 Nov 2025

Study clarifies how spermine can guard against Alzheimer’s and Parkinson’s

Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together.

21 Nov 2025