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New guidance for the diagnosis and management of inherited hyperbilirubinemia

Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting bilirubin metabolism and transport.

10 Feb 2026

Stiff red blood cells drive sickle cell disease severity

A new breakthrough study led by researchers at the University of Minnesota Twin Cities could explain why patients with the same genetic sickle cell mutation experience different levels of pain, organ damage and response to treatment.

10 Feb 2026

Study reveals how inherited genetic abnormalities raise Barrett’s esophagus risk

Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett's esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, one of the fastest-spreading and deadliest forms of cancer.

10 Feb 2026

Dual targeting strategy suppresses pancreatic cancer cell growth

A new research paper was published in Volume 13 of Oncoscience on January 28, 2026, titled "Dual targeting of oncogenic microtubules and mitochondria in PDAC."

10 Feb 2026

Choroid plexus enlargement in Long COVID signals cognitive risk

The increased size of, and lesser blood supply to, a key brain structure in patients with Long COVID tracks with known blood markers of Alzheimer's disease and greater levels of dementia, a new study finds.

10 Feb 2026

Early bone molecular changes signal osteoarthritis progression

Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease progression before cartilage loss.

10 Feb 2026

Type 2 diabetes and hypertension share a genetic link, study shows

Type 2 diabetes and high blood pressure share a genetic link, new research from the University of Surrey, UK and the Université de Lille, France shows.

10 Feb 2026

New genetic model reveals role of keratin 8 in colorectal cancer development

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients.

10 Feb 2026

AI-powered stethoscopes enable early detection of heart valve disease

Artificial intelligence could help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives, a new study suggests.

10 Feb 2026

Beta arrestin 1 emerges as key driver of pulmonary hypertension

Researchers have uncovered the pivotal role of a previously overlooked protein in the development of the serious illness.

10 Feb 2026

US cancer institute studying ivermectin’s ‘ability to kill cancer cells’

The National Cancer Institute, the federal research agency charged with leading the war against the nation's second-largest killer, is studying ivermectin as a potential cancer treatment, according to its top official.

10 Feb 2026

Influenza viruses can directly impair heart function

Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk of a heart attack or other major cardiovascular event.

9 Feb 2026

FDA label update expands CAR T access for primary CNS lymphoma

Dana-Farber Cancer Institute-led research helped drive an FDA label update for axicabtagene ciloleucel (Yescarta) that removes a prior exclusion for patients with primary central nervous system lymphoma, a rare and aggressive lymphoma of the brain and spinal cord.

9 Feb 2026

Defective fat cells drive metabolic disease in lipodystrophy

Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose as a necessary and metabolically active organ, carrying out many vital functions within the body.

9 Feb 2026

Low-grade inflammation connects aging, obesity and cognitive impairment

Obesity and older age are strongly associated with low-grade inflammation in the body, a condition that appears closely linked to cognitive decline and dementia.

9 Feb 2026

Engineered CAR-T cells reduce Alzheimer’s plaques in mice

Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers.

9 Feb 2026

Obesity drives one in ten infectious disease deaths

Just over one in 10 deaths from a wide range of infectious diseases can be attributed to obesity worldwide, finds a major new study led by a University College London (UCL) researcher.

9 Feb 2026

Tirzepatide shows dual benefits in sleep apnea trial improving metabolism and reducing inflammation

Tirzepatide significantly improved cardiometabolic risk markers in adults with obesity and moderate to severe obstructive sleep apnea in the SURMOUNT-OSA phase 3 trials. Mediation analyses suggest both weight loss and reduced sleep-disordered breathing contributed to improvements in inflammation, insulin resistance, lipids, and blood pressure.

9 Feb 2026

Medicare's three-day rule: Longer hospital stays, no patient benefit

A long-standing Medicare policy meant to manage rehabilitation services in nursing homes may keep older Americans in hospitals longer than necessary without improving patient health or saving Medicare money, new research finds.

9 Feb 2026

Nervous system actively promotes pre-cancerous pancreatic lesions

Pancreatic cancer has a lot of nerve. Notoriously tricky to detect, the disease also often resists traditional therapy. So, researchers are urgently looking for new ways to disrupt tumor formation.

9 Feb 2026