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Wireless retinal implant restores sight in patients blinded by advanced macular degeneration

A new trial shows that a wireless subretinal implant, the PRIMA system, restored central vision in patients with geographic atrophy caused by age-related macular degeneration. After one year, 81% achieved clinically meaningful vision gains and most could read at home using prosthetic vision.

28 Oct 2025

Innovative approach to enhancing laser lithotripsy for kidney stones

During a procedure known as laser lithotripsy, urologists use a small, video-guided laser to blast painful, potentially damaging kidney stones to smithereens.

28 Oct 2025

Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder

In a peer-reviewed article published today in Brain Medicine, a European research team presents a focused review of emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder (OCD).

28 Oct 2025

Exploring the gut-brain-immune axis in neurodegeneration

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.

28 Oct 2025

Clinical Frailty Scale can quickly predict mortality in patients with heart failure

Frailty is closely linked to adverse outcomes in older adults, particularly those with heart failure. Numerous epidemiologic studies show that frailty has important prognostic value in this population, underscoring the need for routine assessment.

28 Oct 2025

Study highlights non-inferiority of super-high-pressure non-compliant balloons in coronary interventions

New study findings show that utilizing super-high-pressure non-compliant balloons (NCB) is non-inferior to intravascular lithotripsy (IVL) balloon catheters for lesion preparation and stent expansion in severely calcified lesions during percutaneous coronary intervention (PCI).

28 Oct 2025

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Results from the first randomized clinical trial in the United States to compare a sirolimus-eluting balloon (DEB) to control group consisting of drug-eluting stent (DES) and balloon angioplasty (BA) for the treatment of bare-metal and DES in-stent restenosis (ISR) deemed DEB to be noninferior to conventional therapies.

28 Oct 2025

Cutting balloon angioplasty proves noninferior to intravascular lithotripsy in treating calcified coronary lesions

Results from the first randomized controlled trial to directly compare the safety and efficacy of cutting balloon (CB) angioplasty to intravascular lithotripsy (IVL) prior to drug-eluting stent (DES) implantation for the treatment of calcified coronary artery disease found CB to be noninferior to IVL.

28 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

Reducing prescriptions of sleep drugs in older adults could provide health and economic benefits

Millions of older Americans suffering from insomnia regularly use prescription sleep medications, despite the risk of serious side effects-such as falls, broken bones

28 Oct 2025

Circadian rhythm disruptions may increase the risk of cardiovascular disease

As modern lifestyles increasingly challenge the body's natural circadian rhythm, the American Heart Association is spotlighting the potential health consequences of regular disruptions to our body's internal clock with a new scientific statement published today in its flagship journal Circulation.

28 Oct 2025

Subtle brain changes in football players could predict the risk of chronic traumatic encephalopathy

Brain scans from American football players reveal subtle differences in the brain's outer grooves when compared to scans from otherwise healthy men who never played contact or collision sports, a new study shows.

28 Oct 2025

BD² expands global effort to examine the key mechanisms of bipolar disorder

Today, BD², or Breakthrough Discoveries for thriving with Bipolar Disorder, announced its third round of Discovery Research grants, totaling nearly $18 million – expanding a comprehensive global effort to examine the key mechanisms of bipolar disorder.

28 Oct 2025

Liver cirrhosis found to be more common in low-income households

Liver cirrhosis is significantly more common in low-income households than in high-income households. This is the result of a national study which, according to the researchers, calls for more preventive action in the most vulnerable groups.

28 Oct 2025

New drug can have a promising effect in cancer patients with active brain metastases

An international clinical study led by the Medical University of Vienna shows that the drug patritumab deruxtecan (HER3-DXd) can have a promising effect in patients with active brain metastases of various tumor types.

28 Oct 2025

Electronic health record data reveals trends in cardiovascular diseases before and after COVID-19

The electronic health record data analyzed in this study is anonymized and never leaves a secure data environment, which is only accessible by approved researchers working on approved projects.

28 Oct 2025

Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders

Most people are born with two functioning copies of each gene-one inherited from each parent. In many cases, having just one working copy is enough for the body to function normally.

28 Oct 2025

Air pollution, even below EPA guidelines, increases breast cancer risk

Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more than 400,000 women and 28,000 breast cancer cases.

28 Oct 2025

Clinically significant valvular heart disease vastly underdiagnosed in U.S. elders

Results from the PREVUE-VALVE study suggest that there are currently at least 4.7 million people aged 65-85 living with moderate or greater valvular heart disease (VHD) in the United States, and at least 10.6 million with clinically significant VHD, most of whom are unaware of their condition.

28 Oct 2025

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria

27 Oct 2025

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Medical Condition News

Wireless retinal implant restores sight in patients blinded by advanced macular degeneration

Innovative approach to enhancing laser lithotripsy for kidney stones

Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder

Exploring the gut-brain-immune axis in neurodegeneration

Clinical Frailty Scale can quickly predict mortality in patients with heart failure

Study highlights non-inferiority of super-high-pressure non-compliant balloons in coronary interventions

Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis

Cutting balloon angioplasty proves noninferior to intravascular lithotripsy in treating calcified coronary lesions

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

Reducing prescriptions of sleep drugs in older adults could provide health and economic benefits

Circadian rhythm disruptions may increase the risk of cardiovascular disease

Subtle brain changes in football players could predict the risk of chronic traumatic encephalopathy

BD² expands global effort to examine the key mechanisms of bipolar disorder

Liver cirrhosis found to be more common in low-income households

New drug can have a promising effect in cancer patients with active brain metastases

Electronic health record data reveals trends in cardiovascular diseases before and after COVID-19

Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders

Air pollution, even below EPA guidelines, increases breast cancer risk

Clinically significant valvular heart disease vastly underdiagnosed in U.S. elders

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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