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Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a study published by The BMJ today.

5 Jun 2025

Type 2 diabetes drug shows improvements for patients with progressive liver disease

The sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin, widely used to treat type 2 diabetes, also shows improvements for patients with progressive liver disease, finds a clinical trial from China published by The BMJ today.

5 Jun 2025

Innovative method reveals how titin disruption triggers muscular diseases

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an innovative method, called TEVs-TTN, for studying the specific mechanical functions of proteins through their controlled cleavage, a process that renders the proteins unable to sense and transmit mechanical force.

5 Jun 2025

Talking therapy boosts recovery in stroke survivors with depression or anxiety

Stroke survivors with depression or anxiety who attend talking therapy sessions are more likely to recover from their psychological symptoms, finds a new study by UCL researchers.

5 Jun 2025

Statins show no additional benefit for depression treatment

Lipid-lowering medicines, known as statins, are prescribed in cases of high cholesterol levels, to reduce the risk of atherosclerosis, heart attack and stroke.

4 Jun 2025

Personalized exercise and coaching could improve health of people with neuromuscular diseases

While many people with neuromuscular diseases currently face a future without a cure, a new study finds that a personalized exercise and coaching program could improve their fitness and overall health.

4 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

Back-to-basics, 'not fad' diets beat heart disease and diabetes

This review examines dietary interventions that can improve cardiometabolic health, highlighting the role of whole foods in reducing heart disease and diabetes.

4 Jun 2025

FDA approves ENCELTO implant to preserve sight in people with macular telangiectasia type 2

For people diagnosed with macular telangiectasia type 2 (MacTel)-a rare and slowly progressing retinal disease-there have been no FDA-approved (or other) treatments to slow or stop vision loss.

4 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

Rethinking healthcare through the science of aging

A new editorial was published in Aging (Aging-US) Volume 17, Issue 5, on May 29, 2025, titled "Rethinking healthcare through aging biology."

4 Jun 2025

Novel deep learning model leverages real-time data to assist in diagnosing nystagmus

Artificial intelligence is playing an increasingly vital role in modern medicine, particularly in interpreting medical images to help clinicians assess disease severity, guide treatment decisions and monitor disease progression.

4 Jun 2025

Study shows survival benefit of surgical ablation during CABG in patients with atrial fibrillation

A new study published in The Annals of Thoracic Surgery, a journal from The Society of Thoracic Surgeons, finds that Medicare patients with atrial fibrillation (AF) who undergo surgical ablation during isolated coronary artery bypass grafting (CABG) live longer than those who do not, offering compelling support for clinical guidelines that recommend this procedure but are too often not followed in practice.

4 Jun 2025

New technique improve success rates in treating strokes and other clot-related diseases

When treating an ischemic stroke – where a clot is blocking the flow of oxygen to the brain – every minute counts.

4 Jun 2025

Switching to a low fat diet slows pancreatic precancer development in mice

Pancreatic cancer is one of the deadliest forms of cancer, killing 87% of patients within five years. Previous studies have shown that obesity can increase pancreatic cancer risk by around 50%.

4 Jun 2025

Y chromosome loss linked to poor cancer outcomes

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

4 Jun 2025

Study highlights the lasting toll of colorectal cancer on women's sexual health

A new University of British Columbia-led study is shedding light on a long-overlooked consequence of colorectal cancer: the lasting toll it can take on women's sexual health, even years after treatment ends.

4 Jun 2025

New screening tool enhances early detection of pulmonary hypertension

A novel screening approach developed by physicians at the Lewis Katz School of Medicine at Temple University shows significant promise for improving the detection of pulmonary arterial hypertension (PAH)-a life-threatening form of heart failure related to high blood pressure in the lung circulation that is often overlooked due to vague symptoms such as fatigue and shortness of breath.

4 Jun 2025

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Medical Condition News

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Type 2 diabetes drug shows improvements for patients with progressive liver disease

Innovative method reveals how titin disruption triggers muscular diseases

Talking therapy boosts recovery in stroke survivors with depression or anxiety

Statins show no additional benefit for depression treatment

Personalized exercise and coaching could improve health of people with neuromuscular diseases

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Back-to-basics, 'not fad' diets beat heart disease and diabetes

FDA approves ENCELTO implant to preserve sight in people with macular telangiectasia type 2

Integrating discoveries with translational science to transform Alzheimer's care

Rethinking healthcare through the science of aging

Novel deep learning model leverages real-time data to assist in diagnosing nystagmus

Study shows survival benefit of surgical ablation during CABG in patients with atrial fibrillation

New technique improve success rates in treating strokes and other clot-related diseases

Switching to a low fat diet slows pancreatic precancer development in mice

Y chromosome loss linked to poor cancer outcomes

Study highlights the lasting toll of colorectal cancer on women's sexual health

New screening tool enhances early detection of pulmonary hypertension

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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