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Researchers use algorithm to pinpoint disease risk mutations in noncoding DNA

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

17 Apr 2025

Study unveils genetic pathway leading to cleft lip and palate formation

Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United States.

17 Apr 2025

New discovery enhances cell entry for complex cancer drugs

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

17 Apr 2025

Nontraditional risk factors linked to stroke in adults under 50

Adults younger than 50 years of age had more than double the risk of having a stroke from migraine or other nontraditional stroke risk factors rather than traditional risks such as high blood pressure, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

17 Apr 2025

Survey reveals low awareness of innovative cancer treatment among Americans

Roswell Park Comprehensive Cancer Center is at the forefront of a new approach to cancer treatment, called CAR T-cell therapy.

17 Apr 2025

Best time for asthma meds? Try 4 pm

Chronotherapy for asthma reveals that afternoon inhaled corticosteroids significantly improve lung function and reduce nighttime symptoms without side effects.

17 Apr 2025

New Canadian guidelines offer comprehensive approach to managing pediatric obesity

Researchers provide evidence-based recommendations to manage pediatric obesity.

17 Apr 2025

Seasonal air pollution found to undermine IVF success

Exposure to fine particulate matter during fertility treatment windows—especially in winter—negatively impacts pregnancy and live birth rates

17 Apr 2025

Mount Sinai Fuster Heart Hospital earns national recognition for patient care excellence

The Mount Sinai Fuster Heart Hospital's cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, one of the nation's leading patient experience organizations.

16 Apr 2025

Many stroke patients with carotid artery narrowing may avoid surgery, research shows

European research led by University College London (UCL), together with Amsterdam UMC and the University of Basel shows that a significant proportion of patients who suffer a stroke due to carotid artery narrowing can be treated with medication only.

16 Apr 2025

Metabolic syndrome found to increase risk of breast cancer recurrence and death

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic profile or so called 'metabolic syndrome' increases the risk of breast cancer recurrence by 69%, and subsequent breast cancer mortality by 83%.

16 Apr 2025

Sex and age play key roles in dementia biomarker levels

A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood, according to a study published on April 16, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

16 Apr 2025

FOXR2 activation found in multiple pediatric brain tumor types

Physicians classify brain tumors and determine treatment options, in part, by the genes they express. According to World Health Organization standards, the abnormal activation of oncogene FOXR2 only occurs in central nervous system (CNS) neuroblastoma, but that may not be true.

16 Apr 2025

Harnessing the healing power of music in clinical care

Rhonda Winegar remembers watching the 2014 documentary "I'll Be Me," which chronicled country music legend Glen Campbell's struggles with Alzheimer's disease.

16 Apr 2025

Gold nanoparticles offer new hope for vision restoration

A new study by Brown University researchers suggests that gold nanoparticles - microscopic bits of gold thousands of times thinner than a human hair - might one day be used to help restore vision in people with macular degeneration and other retinal disorders.

16 Apr 2025