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People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

First-generation antihistamines increase delirium risk in older hospitalized patients

An analysis in the Journal of the American Geriatrics Society reveals that older inpatients admitted to physicians who prescribe higher amounts of first-generation antihistamines face an elevated risk of delirium while in the hospital.

22 Oct 2025

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

22 Oct 2025

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University of Technology, University of Queensland, and Nanjing Stomatological Hospital has introduced groundbreaking three-dimensional (3D) dynamic cell co-culture models to simulate metabolic dysfunction-associated steatotic liver disease (MASLD) progression stages.

22 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.

22 Oct 2025

$VT3989 shows promising antitumor activity in refractory mesothelioma patients$

VT3989 shows promising antitumor activity in refractory mesothelioma patients

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led by researchers from The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Study links child behavior stress and lower self-regulation in parents

Any parent will tell you that raising a child isn't easy. While the experience can be filled with joy and love and fulfilment, emotional, financial and marital stress will present challenges to any family.

22 Oct 2025

Noninvasive optical system measures blood flow with precision

Measuring how well blood flows to the brain is crucial for understanding a wide range of neurological issues, from strokes to migraines to traumatic brain injuries. Obtaining such measurements noninvasively, however, remains a challenge. The scalp and skull not only obstruct viewing the brain directly but also have their own blood supply, further complicating cerebral blood flow measurements.

22 Oct 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Strong grip strength lowers risk of organ dysfunction in obesity

People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.

21 Oct 2025

Epidural stimulation and physical rehabilitation can enhance recovery in spinal cord injury patients

Spinal cord injury (SCI) causes paralysis in roughly one million people worldwide, with incident cases rising yearly.

21 Oct 2025

New study details how AI chatbots systematically violate ethical standards of practice

As more people turn to ChatGPT and other large language models (LLMs) for mental health advice, a new study details how these chatbots - even when prompted to use evidence-based psychotherapy techniques - systematically violate ethical standards of practice established by organizations like the American Psychological Association.

21 Oct 2025

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary human T cells, addressing a key manufacturing and scalability challenge in next-generation cell therapies.

21 Oct 2025

Predictive factors for physical activity behavior change after cardiovascular diagnosis

Brain connectivity patterns and environmental factors predict which older adults will successfully increase physical activity after receiving a cardiovascular diagnosis.

21 Oct 2025

Stressful life factors early in life may triple the risk of developing psoriasis later

New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life.

21 Oct 2025

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Medical Condition News

People with multiple sclerosis found to have dysbiotic oral microbiome

First-generation antihistamines increase delirium risk in older hospitalized patients

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

New drug combination shows promise in treating colorectal cancer

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

VT3989 shows promising antitumor activity in refractory mesothelioma patients

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Discovery offers a breakthrough approach to combat prostate tumor growth

Study links child behavior stress and lower self-regulation in parents

Noninvasive optical system measures blood flow with precision

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Strong grip strength lowers risk of organ dysfunction in obesity

Epidural stimulation and physical rehabilitation can enhance recovery in spinal cord injury patients

New study details how AI chatbots systematically violate ethical standards of practice

Epigenetic editing enables safer and more effective T cell therapies

Predictive factors for physical activity behavior change after cardiovascular diagnosis

Stressful life factors early in life may triple the risk of developing psoriasis later

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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