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New review reveals complex polygenic architecture underlying common epilepsies

An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide association studies, whole-exome sequencing projects, and advanced statistical modeling to illuminate the polygenic architecture that underpins these heterogeneous neurological disorders.

10 Mar 2026

Wegovy linked to higher risk of eye stroke and vision loss

Wegovy, a GLP-1 agonist for weight loss, may carry the highest risk of 'eye stroke' (ischemic optic neuropathy) and sudden sight loss of the semaglutide drugs, finds an analysis of unintended side effect reports published in the British Journal of Ophthalmology.

10 Mar 2026

AI-powered wearable ECG system detects myocardial ischemia minutes earlier

Myocardial ischemia, the primary driver of heart attacks, remains the leading cause of death and disability worldwide. Delays in diagnosis directly correlate with increased myocardial necrosis, higher complication rates, and elevated mortality.

10 Mar 2026

New consensus defines oligometastatic stage in pancreatic cancer

Until now, the following has been true for metastatic pancreatic cancer: Once the tumor has spread, local treatment such as surgery is usually no longer an option.

10 Mar 2026

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling.

10 Mar 2026

Study links p-tau217 levels to long-term dementia risk in women

Researchers from the University of California San Diego have found that a novel blood-based biomarker can predict a woman's risk of developing dementia as many as 25 years before symptoms appear.

10 Mar 2026

Stroke survivors under 50 face greater cognitive and mental health challenges

Analysis of a large, nationally representative survey shows that stroke survivors under age 50 have more problems concentrating and running errands and experience more poor mental health days than older stroke survivors do.

10 Mar 2026

Holding blood thinners for too long may jeopardize surgical recovery

Blood thinners are a common medication for much of the older adult population, prescribed to prevent blood clots that can cause adverse events like heart attack or stroke.

10 Mar 2026

Depleting a clotting protein fibrinogen could slow down pancreatic cancer

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that depleting a clotting protein made by the liver could slow down pancreatic cancer.

10 Mar 2026

Cellular energy changes may help detect early-stage major depression

Researchers may have discovered a new way to diagnose and treat major depression at the earliest stage of the condition, giving patients the best opportunity for recovery.

10 Mar 2026

Targeting IGF2BP2 improves anti-angiogenic therapy effectiveness in colorectal cancer

A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment in colorectal cancer (CRC).

10 Mar 2026

How social and environmental exposures across life influence mental health risk

Researchers outline how the exposome framework, which captures the totality of environmental exposures across the lifespan, can help explain how non-genetic factors shape mental health risk and resilience. The perspective highlights how integrating environmental, biological, and social data could improve prevention strategies, research models, and personalized mental health care.

10 Mar 2026

New biotech partnership aims to accelerate stem cell therapies for heart disease

A new biotech company forged through an Australian and Danish partnership will accelerate treatments for children and adults with heart disease. Harnessing cellular therapies, the company aims to conduct human clinical trials within three to five years.

10 Mar 2026

Immune cells found to actively promote plaque formation in Alzheimer’s disease

A new study led by researchers from VIB and KU Leuven shows that immune cells called microglia can actively promote the formation of plaques in Alzheimer's disease, challenging the long-standing view that these cells serve only as defenders against plaque buildup.

10 Mar 2026

Researchers develop DNA aptamer to detect Alzheimer's biomarkers

With aging populations on the rise, the need for better tools to diagnose and monitor Alzheimer's disease (AD), the most common cause of dementia, has never been more urgent.

10 Mar 2026

Using a smartwatch to detect changes in brain health

Can smartphones or smartwatches help detect early signs of neurological or mental illness? Researchers at the University of Geneva (UNIGE) monitored a group of participants wearing connected devices, and used artificial intelligence to analyze data such as heart rate, physical activity, sleep and air pollution.

10 Mar 2026

Novel microneedle patch accelerates healing of chronic diabetic wounds using light

Researchers from Nanjing Drum Tower Hospital, Southeast University, and Wenzhou Medical University have developed a novel microneedle patch that combines MXene hydrogel with nitric oxide (NO) and hypoxia-inducible factor-1α (HIF-1α) plasmid for enhanced diabetic wound treatment.

10 Mar 2026