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Research explores how photo-oxidized sterols kill melanoma cells

Melanoma is the most aggressive form of skin cancer. Although less common, it is the most serious due to its high potential for metastasis.

16 Apr 2025

New hope for sclerosteosis patients through Wnt pathway inhibition

Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can lead to severe health issues such as hearing loss and increased intracranial pressure.

16 Apr 2025

Diabetes medications may help shield the brain from cognitive decline

A study led by researchers in the University of Florida College of Pharmacy has found that a pair of popular glucose-lowering medications may have protective effects against the development of Alzheimer's disease and related dementias in patients with Type 2 diabetes.

16 Apr 2025

Comparing single cell RNA methods to improve gastrointestinal cancer research

Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the cells that go awry to cause these diseases.

16 Apr 2025

Stem cell therapy shows promise for treating advanced Parkinson's disease

A stem cell–based therapy initially developed at Memorial Sloan Kettering Cancer Center (MSK) may lead to a new treatment for advanced Parkinson's disease, according to results from a phase 1 clinical trial reported in Nature.

16 Apr 2025

Early detection of Alzheimer's disease through blood biomarker

Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms.

16 Apr 2025

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

A multidisciplinary clinical team led by Professor Bernat Soria from the Institute of Bioengineering at the Miguel Hernández University of Elche (UMH, Spain) has developed a new method to deliver cell therapies in patients on extracorporeal membrane oxygenation (ECMO), a life support system used in cases of severe lung failure.

16 Apr 2025

Brisk walking linked to lower risk of heart rhythm disorders

A brisk walking pace, and the amount of time spent at this speed, may lower the risk of heart rhythm abnormalities, such as atrial fibrillation, tachycardia (rapid heartbeat), and bradycardia (very slow heartbeat), finds research published online in the journal Heart.

16 Apr 2025

Nature based activities improve mental health in just twelve weeks

Researchers evaluating a nature-based programme of activities for patients with mild to moderate mental health conditions have shown that improvements in mood and anxiety levels can be seen in as little as 12 weeks.

16 Apr 2025

Study links cold hypersensitivity and heaviness in legs to varicose veins

Hypersensitivity to the cold, especially ice cold feet, as well as a feeling of heaviness in the legs, are linked to the presence of varicose veins, finds a large study published in the open access journal Open Heart.

16 Apr 2025

Medicaid expansion improves access to high-volume hospitals for lung cancer patients

A new study published in The Annals of Thoracic Surgery, the flagship journal from The Society of Thoracic Surgeons, suggests that Medicaid expansion under the Affordable Care Act has significantly improved access to timely treatment and high-volume hospitals for patients with early-stage non-small cell lung cancer (NSCLC).

16 Apr 2025

Music therapy intervention improves mental health for heart failure and COPD patients

A new study from University Hospitals Connor Whole Health found that it was feasible to conduct a hybrid music therapy intervention for patients with heart failure and patients with chronic obstructive pulmonary disease (COPD).

16 Apr 2025

UC researchers receive $200,000 grant to design user-friendly exoskeleton for spinal cord injury patients

For people with spinal cord injuries/diseases (SCI/D), performing daily tasks can be a challenge due to an impaired ability to grasp and manipulate objects with their hands.

16 Apr 2025

Early combination treatment can prevent heart attacks and save lives

Patients who receive an add-on medication soon after a heart attack have a significantly better prognosis than those who receive it later, or not all.

16 Apr 2025

Study: Climate trauma can have lasting effects on cognitive function

A new study from University of California San Diego suggests that climate trauma - such as experiencing a devastating wildfire - can have lasting effects on cognitive function.

16 Apr 2025

Gut bacteria turn bile acids into allies against cancer

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators.

16 Apr 2025

Nasal protein levels may predict COVID-19 risk

Higher nasal expression of ACE2 and TMPRSS2 proteins can predict future SARS-CoV-2 infection.

16 Apr 2025

New genetic clues uncovered in epilepsy drug resistance

Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global study led by researchers at UCL and UTHealth Houston.

16 Apr 2025

Modified Japanese diet shows promise for lowering blood pressure, study finds

A study of 12,213 Japanese workers found no link between hypertension and the traditional Japanese diet, but a modified version emphasizing whole grains, fruits, and dairy showed a potential protective effect. The findings highlight how modernizing traditional diets with nutrient-rich foods may combat high blood pressure.

16 Apr 2025

Low vitamin D levels damage erectile health via superoxide surge, study finds

Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as shown in human tissue and animal models. This breakthrough reveals why low vitamin D may lead to poor sexual health and resistance to standard ED treatments.

15 Apr 2025