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Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Super-enhancers: Cancer's double-edged sword of growth and DNA damage

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive unusually intense gene activity.

22 Jan 2026

New medical LLM detects depression in women via WhatsApp audio analysis

A new medical large language model (LLM) achieved over 91 percent accuracy in identifying female participants diagnosed with major depressive disorder after analyzing a short WhatsApp audio recording where participants described their week, according to a study published January 21, 2026 in the open-access journal PLOS Mental Health by Victor H. O. Otani, from Santa Casa de São Paulo School of Medical Sciences and Infinity Doctors Inc., Brazil, and colleagues.

22 Jan 2026

Study identifies a powerful strategy to overcome drug resistance in breast cancer

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6.

22 Jan 2026

Chemotherapy-induced gut changes trigger anti-metastatic immune response

Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to the gut.

22 Jan 2026

Smartwatches improve the detection of atrial fibrillation

Smartwatches with both PPG and ECG functionality improve the detection of atrial fibrillation in comparison with standard care.

22 Jan 2026

AI tool predicts metastatic risk in multiple cancers

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown — yet understanding this is crucial for optimizing patient care.

22 Jan 2026

Bacteria behind Nagashima-type palmoplantar keratosis foot odor identified

The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the overgrowth of a specific bacterial strain.

22 Jan 2026

Large study identifies more than 100 genetic regions linked to schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

21 Jan 2026

Understanding tumor growth patterns helps guide treatment after lung cancer

When lung cancer treatment stops working, what happens next? New research reveals the answer may depend on how the cancer grows.

21 Jan 2026

Reducing alcohol consumption could significantly lower cancer deaths

Reducing annual alcohol consumption in Australia by one litre a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.

21 Jan 2026

Gaps in stroke transfer system reduces survivors' chances of receiving critical treatment

Gaps in the U.S. stroke transfer system are drastically reducing survivors' chances of receiving critical treatment and increasing the likelihood that they will leave the hospital with a disability, according to a new study published in The Lancet Neurology.

21 Jan 2026

UC Irvine wins ARPA-H award to advance lymphatic disease diagnosis

The University of California, Irvine has received its first award from the Advanced Research Projects Agency for Health, launching a major effort to improve how doctors detect and treat diseases of the lymphatic system.

21 Jan 2026

Red light therapy may protect athletes' brains from repetitive impacts

Punch-drunk syndrome, boxer's madness, chronic traumatic encephalopathy (CTE). The name has changed over the years, but the cause is clear: repeated impacts can affect long-term brain health, with symptoms ranging from confusion to memory loss and potentially dementia.

21 Jan 2026

More urban trees associated with fewer heart disease cases

A multi-institutional study led by the University of California, Davis, finds that living in urban areas with a higher percentage of visible trees is associated with a 4% decrease in cardiovascular disease.

21 Jan 2026

Long-term proton pump inhibitor use not linked to stomach cancer

The long term use of proton pump inhibitors (PPIs), a class of drugs widely used to treat acid reflux and ulcers, may not be linked to any increased risk of developing gastric (stomach) cancer, finds a study of Nordic health data published by The BMJ today.

21 Jan 2026

GLP-1 weight-loss drugs show early promise for treating addiction

This systematic review evaluates preclinical and clinical evidence on glucagon-like peptide-1 receptor agonists as potential treatments for substance use disorders. Findings show consistent reductions in drug- and alcohol-seeking behaviors in animal models, while human evidence remains limited, heterogeneous, and preliminary.

21 Jan 2026

Stroke transfer delays reduce access to life-saving thrombectomy

Gaps in the nation's stroke transfer system are drastically reducing survivors' chances of receiving critical treatment and increasing the likelihood that they will leave the hospital with a disability, a new study suggests.

21 Jan 2026

Pandemic linked to lasting drops in diagnosis rates for major conditions

There has been a lasting and disproportionate impact of the Covid-19 pandemic on diagnosis rates for conditions including depression, asthma and osteoporosis.

21 Jan 2026

Long-term air pollution exposure raises motor neuron disease risk

Long-term exposure to ambient air pollution was associated with a higher risk of developing motor neuron disease and poorer prognosis after diagnosis in a large nationwide Swedish study. Higher particulate matter and nitrogen dioxide exposure were also linked to faster functional decline and increased likelihood of invasive ventilation.

21 Jan 2026