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Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Getting treatment within one week of a serious head injury can reduce the risk of developing Alzheimer's disease by up to 41%, according to new research from Case Western Reserve University.

25 Nov 2025

Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Mechanical valve replacement is a primary treatment for rheumatic heart disease, yet prosthesis-related adverse outcomes remain underreported in India.

25 Nov 2025

Zanidatamab shows durable and meaningful responses in HER2-positive biliary tract cancer

Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

25 Nov 2025

White matter alterations connect coronary artery disease to cognitive decline

Individuals with coronary artery disease (CAD) - a constricting or blocking of blood vessels feeding the heart - face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood.

25 Nov 2025

Daily walking patterns help flag early Parkinson’s signs in large UK study

Accelerometer data from nearly 95,000 adults show that higher daily step counts predict lower short-term Parkinson’s disease risk. But as follow-up extends, the association fades, indicating that reduced steps are more likely an early marker than a cause.

25 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Extreme heat waves pose death risk for veterans with cardiometabolic conditions

Veterans living in California who have cardiometabolic conditions such as diabetes and high blood pressure experience significantly higher risk of dying during heat waves compared to cooler days, UCLA-led research finds.

25 Nov 2025

New medication offers potential treatment for patients with deadliest form of blood cancer

Biomedical research that began at the University of Virginia School of Medicine has yielded a much-needed new treatment for patients with the deadliest form of blood cancer.

25 Nov 2025

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline.

25 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

The ABC method for improving mental health

These are troubling times, where there is much to worry about. Emergency preparedness has suddenly become a highly relevant topic, and many people are plagued by a sense of unease and even fear.

25 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

Electroconvulsive therapy found to be highly effective in treating elderly patients with depression

Electroconvulsive therapy is a safe and effective treatment for elderly patients suffering from depression.

25 Nov 2025

Unraveling the mycobiome's role in cancer

A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response.

25 Nov 2025

Using a prebiotic after traumatic brain injury may help reduce impulsive behavior

Using a prebiotic to influence bacterial activity in the gut after a traumatic brain injury may help reduce impulsive behavior, one of the common symptoms to follow a moderate blow to the head, a new study in rats suggests.

25 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

In a new JNeurosci paper, Tian-Ming Gao and colleagues, from Southern Medical University, explored how adenosine triphosphate (ATP) signaling relates to depression and anxiety using male mice. ATP is a molecule that not only provides energy but also supports communication between neurons.

25 Nov 2025

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Using a deep learning AI model, researchers identified the first-of-its-kind biomarker of chronic stress detectable through routine imaging, according to research being presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2025

Autistic adults show higher rates of self-harm and suicide plans regardless of trauma history

Autistic people are more likely to report suicide-related behaviors and psychological distress irrespective of previous traumatic experiences, according to new research from the University of Cambridge.

25 Nov 2025

Medical Condition News

Obesity-related metabolic stress may affect brain health far earlier than expected

Early treatment after head injury lowers long-term risk of Alzheimer’s disease

Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Zanidatamab shows durable and meaningful responses in HER2-positive biliary tract cancer

White matter alterations connect coronary artery disease to cognitive decline

Daily walking patterns help flag early Parkinson’s signs in large UK study

Genetic signals reveal why erectile dysfunction develops and who is most at risk

Extreme heat waves pose death risk for veterans with cardiometabolic conditions

New medication offers potential treatment for patients with deadliest form of blood cancer

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Infection-related hospital stays linked to higher risk of developing dementia

The ABC method for improving mental health

New skin-permeable polymer delivers insulin without needles

Electroconvulsive therapy found to be highly effective in treating elderly patients with depression

Unraveling the mycobiome's role in cancer

Using a prebiotic after traumatic brain injury may help reduce impulsive behavior

Scientists uncover how brain enzyme OTULIN controls tau expression

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Autistic adults show higher rates of self-harm and suicide plans regardless of trauma history

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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