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Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.

7 Dec 2025

Virtual diet and exercise program shows promise in reducing lymphoma treatment side effects

Patients undergoing treatment for lymphoma often experience adverse side effects that can be so severe that they stop or slow treatment.

7 Dec 2025

Kiwifruit intake boosts vitamin C in skin and supports dermal structure

Study shows that increasing dietary vitamin C intake with kiwifruit raises vitamin C levels in both the dermis and epidermis through active transport from the bloodstream. Higher skin vitamin C levels were associated with increased skin density and epidermal cell proliferation, but not with improved UV protection or measurable increases in new collagen markers.

7 Dec 2025

Shingles vaccination is linked to fewer dementia diagnoses and deaths in older adults

A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed at multiple stages of the dementia disease course.

7 Dec 2025

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Pirtobrutinib, a non-covalent Bruton tyrosine kinase (BTK) inhibitor, met the primary endpoint for non-inferiority in terms of overall response rate in the first head-to-head comparison with ibrutinib, a covalent BTK inhibitor.

7 Dec 2025

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

In a new trial, patients newly diagnosed with acute myeloid leukemia (AML) fared significantly better with a combined regimen of azacitidine and venetoclax compared with conventional induction chemotherapy.

7 Dec 2025

New trial shows major survival gains with epcoritamab added to standard R2 therapy

In a new trial, patients with follicular lymphoma had a significantly higher response to treatment and a nearly 80% reduction in the risk of death or disease progression if they received epcoritamab in addition to the standard second-line regimen versus the standard regimen alone.

7 Dec 2025

Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit

Despite long-standing recommendations, a major updated Cochrane review finds that calcium supplementation during pregnancy does not meaningfully reduce pre-eclampsia risk, prompting a rethink of how best to prevent hypertensive disorders in pregnancy.

7 Dec 2025

Early exposure to fat-related food smells increases lifelong obesity risk

Early exposure to fat-related food odors during development alters central sensory processing and metabolic regulation, independently of maternal obesity or nutrient intake. These sensory cues program long-term susceptibility to obesity, impaired thermogenesis, and altered brain responses to dietary fat in adulthood.

7 Dec 2025

Smartphone motor tests can predict dopamine deficiency in Parkinson’s disease without brain scans

Researchers explore the use of smartphones coupled with clinical scores to evaluate motor function and predict dopamine deficiency.

7 Dec 2025

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

According to a new trial, patients with chronic lymphocytic leukemia (CLL) show comparable outcomes whether they receive a single-agent treatment indefinitely or a combination treatment for a fixed period of time.

7 Dec 2025

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received chemotherapy-based conditioning or total body irradiation (TBI), the standard conditioning regimen used before hematopoietic cell transplantation.

7 Dec 2025

Many families of children with leukemia face significant financial hardship during treatment

Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL) – the most common pediatric cancer – develop serious financial difficulties during their child's treatment, including losing 25% or more of their household income and struggling to cover the costs of basic living expenses such as housing, food, and utilities.

7 Dec 2025

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Treatment with intravenous (IV) iron significantly improved survival and increased hemoglobin levels in patients with iron-deficiency anemia who were hospitalized for an acute bacterial infection, according to an analysis of data from more than 85,000 patients.

7 Dec 2025

Black patients with AML experience earlier onset and poorer outcomes

Compared with white patients, Black patients with acute myeloid leukemia (AML) were on average more than five years younger at diagnosis, more than 30% more likely to die of their disease, and more than 20% more likely to die of any cause, according to an analysis of data conducted over a 34-year period and supported by the National Cancer Institute (NCI) is a component of the U.S. National Institutes of Health.

7 Dec 2025

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.

7 Dec 2025

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

Most Americans still back early hepatitis B vaccination despite policy debate

On December 5, 2025, the Trump administration's Advisory Committee on Immunization Practices (ACIP), whose members were handpicked by Health and Human Services (HHS) Secretary and vaccination critic Robert F. Kennedy Jr., is scheduled to determine whether it should recommend that the Centers for Disease Control and Prevention (CDC) change the recommendation in place since 1991 that newborns be vaccinated against hepatitis B.

5 Dec 2025

$New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer$

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs.

5 Dec 2025

Medical Condition News

Chemotherapy-free combination treatment outperforms traditional regimens in patients with Ph+ ALL

Virtual diet and exercise program shows promise in reducing lymphoma treatment side effects

Kiwifruit intake boosts vitamin C in skin and supports dermal structure

Shingles vaccination is linked to fewer dementia diagnoses and deaths in older adults

Evidence grows for pirtobrutinib as a safer and effective alternative for CLL and SLL

Aza-ven shows superior outcomes compared to induction chemotherapy in AML patients

New trial shows major survival gains with epcoritamab added to standard R2 therapy

Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit

Early exposure to fat-related food smells increases lifelong obesity risk

Smartphone motor tests can predict dopamine deficiency in Parkinson’s disease without brain scans

Fixed-duration therapy works as effectively as continuous treatment for chronic lymphocytic leukemia

Chemotherapy-based conditioning matches outcomes of total body irradiation for MRD-negative B-ALL

Many families of children with leukemia face significant financial hardship during treatment

Intravenous iron shows safe and beneficial outcomes for patients with bacterial infection and anemia

Black patients with AML experience earlier onset and poorer outcomes

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Most sickle cell patients face long delays for recommended pain relief, study shows

Most Americans still back early hepatitis B vaccination despite policy debate

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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