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Sirolimus-eluting balloon emerges as a safe and effective option for coronary in-stent restenosis

A new drug-eluting balloon can perform just as well as the standard treatment for patients with coronary in-stent restenosis (ISR) undergoing repeated percutaneous coronary intervention (PCI).

31 Oct 2025

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear.

31 Oct 2025

Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation

Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction.

31 Oct 2025

GeneSight test-guided treatment leads to faster remission and response in patients with depression

Myriad Genetics, Inc., a leader in molecular diagnostic testing and precision medicine, today announced a post-hoc analysis of the Precision Medicine in Mental Health Care (PRIME) study showed that treatment informed by the GeneSight® test led to faster initial remission and response in patients with Major Depressive Disorder (MDD).

31 Oct 2025

Study reveals how melanoma evolves to resist immunotherapy

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.

31 Oct 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Genetic insights into vestibular system damage from ototoxic drugs

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

31 Oct 2025

Study reports increase in leg and foot amputations in Illinois hospitals from 2016 to 2023

Rates of leg and foot amputations in Illinois hospitals increased 65% between 2016 and 2023, reports a new Northwestern Medicine study.

31 Oct 2025

Breakthrough study maps impact of thousands of variants in heart disease gene

An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease.

31 Oct 2025

Novel approaches to understanding EETs and cardiovascular disease

Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central mediators of inflammation, fever, and pain.

31 Oct 2025

Improving diagnosis, treatment and follow-up care for pulmonary embolism

Pulmonary embolism (PE), a type of blood clot in the lungs, sends more than half a million people to U.S. hospitals each year - and kills about one in five high-risk patients, according to the American Heart Association 2025 statistical update.

31 Oct 2025

Obesity treatment in the UK could become a "two-tier system", experts warn

Treatment for obesity in the UK could become a "two-tier system" where the most vulnerable patients miss out altogether.

31 Oct 2025

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

COVID-19 in pregnancy may raise autism and neurodevelopmental disorder risk

Children born to mothers who contracted COVID-19 during pregnancy face a 29% higher likelihood of developmental disorders by age three, including speech, motor, and autism-spectrum delays. The risk was greatest for male offspring and infections occurring in the third trimester.

30 Oct 2025

Common viruses sharply raise heart attack and stroke risk, major global review shows

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Researchers to study the economics of substance use disorder treatments with $4 million NIDA grant

A team led by Weill Cornell Medicine and University of Miami's Miller School of Medicine investigators has been awarded a five-year, $4 million grant from the National Institute on Drug Abuse (NIDA) for health economics research.

30 Oct 2025

Medical Condition News

Sirolimus-eluting balloon emerges as a safe and effective option for coronary in-stent restenosis

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation

GeneSight test-guided treatment leads to faster remission and response in patients with depression

Study reveals how melanoma evolves to resist immunotherapy

Lab-grown organoid offers a platform to study how liver scarring develops

Genetic insights into vestibular system damage from ototoxic drugs

Study reports increase in leg and foot amputations in Illinois hospitals from 2016 to 2023

Breakthrough study maps impact of thousands of variants in heart disease gene

Novel approaches to understanding EETs and cardiovascular disease

Improving diagnosis, treatment and follow-up care for pulmonary embolism

Obesity treatment in the UK could become a "two-tier system", experts warn

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

Novel nanoparticles can deliver an immune-stimulating molecule directly to ovarian tumors

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

COVID-19 in pregnancy may raise autism and neurodevelopmental disorder risk

Common viruses sharply raise heart attack and stroke risk, major global review shows

Study confirms PSA screening improves survival and safety

Researchers to study the economics of substance use disorder treatments with $4 million NIDA grant

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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