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Rare BTK mutation drives resistance to targeted therapies for blood cancer

Scientists at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, and collaborators have uncovered a rare genetic mutation that enables some blood cancers to evade both approved Bruton tyrosine kinase (BTK) inhibitors and newer BTK degraders, a finding that could help shape the next generation of therapies for patients with chronic lymphocytic leukemia (CLL) and related malignancies.

27 Jul 2026

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

Researchers linked higher plasma TMAO to prevalent atrial fibrillation in 5,090 people and found that TMAO or choline supplementation accelerated AF onset, progression, atrial remodeling, and electrical dysfunction in mice. Inhibiting gut microbial TMA production lowered circulating TMAO and delayed AF in mice, identifying a potential therapeutic pathway that now requires human testing.

27 Jul 2026

Three key brain regions interact during sleep to support memory formation

Researchers at Kennedy Krieger Institute and Johns Hopkins Medicine have discovered that memory consolidation during sleep depends on coordinated activity among three brain regions and disruptions to this activity can impair memory performance.

27 Jul 2026

NIH grant funds study on stroke-related urinary incontinence

Urinary incontinence is a common but frequently overlooked consequence of stroke. Now, researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC and Rancho Los Amigos National Rehabilitation Center have received a grant from the National Institutes of Health to investigate the brain changes responsible for these symptoms and develop a more personalized approach to treatment.

27 Jul 2026

Wearable fingertip patch tracks Parkinson's medication levels through sweat

Engineers and neuroscientists at the University of California San Diego have developed a soft, wearable fingertip patch that continuously tracks a patient's Parkinson's disease medication levels through their sweat.

27 Jul 2026

New cancer vaccine harnesses COVID-19 immune memory to fight tumors

In a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history – a synchronized mass immune memory generated through SARS-CoV-2 infection and vaccination – into a powerful ally against cancer.

27 Jul 2026

Survey shows Native Americans lack awareness of plant-based diets for diabetes prevention

Although Native Americans experience some of the nation's highest rates of type 2 diabetes and other chronic diseases, a new national survey suggests many have not heard about one of the most effective dietary approaches for preventing and even reversing the disease.

27 Jul 2026

UC Davis researcher receives grant to study perceived cognitive aging

University of California, Davis Professor of Neurology Sarah Tomaszewski Farias has been awarded a $3.3 million five-year grant from The National Institute on Aging to study if cultural differences affect how people perceive cognitive changes as they age.

27 Jul 2026

Amyloid beta misfolding predicts Alzheimer's years before symptoms appear

Widely used Alzheimer’s biomarker P-tau 217 reliably detects the disease only at the clinical stage. The protein misfolding of amyloid beta indicates an increased risk years earlier.

27 Jul 2026

New CHEST guideline outlines sleep apnea management during pregnancy

The American College of Chest Physicians (CHEST) recently released a new clinical guideline on obstructive sleep apnea (OSA) in pregnancy.

27 Jul 2026

New blood protein biomarkers estimate timing of ALS symptoms

Months to several years before amyotrophic lateral sclerosis (ALS) symptoms arise, levels of certain blood proteins may dramatically shift.

27 Jul 2026

AI mental health chatbots feel empathetic, but safety evidence still lags

Immune dysregulation may contribute to depression, schizophrenia, bipolar disorder, and anxiety through chronic inflammation, altered neuroimmune signaling, genetic susceptibility, and stress-related epigenetic changes. Evidence also suggests that biologically defined patient subgroups may benefit from more precise, immune-informed approaches to diagnosis and treatment.

27 Jul 2026

Study links inherited genetics to cancer susceptibility and progression

Scientists have found the first direct evidence of the powerful role our genetic makeup plays in influencing our risk of cancer, with inherited genes interacting with acquired genetic mutations to shape how tumors evolve.

26 Jul 2026

Study identifies simvastatin as promising adjuvant for periodontitis treatment

Porphyromonas gingivalis can evade antibiotics by invading host cells, contributing to recurrent periodontitis and persistent tissue damage.

26 Jul 2026

Researchers uncover molecular switch controlling nutrient-driven cell growth

Cells carry their own growth switches. When enough nutrients-amino acids in particular-are available, cells flip this switch on and begin to grow. Researchers at KAIST and Yonsei University have now uncovered the molecular mechanism by which amino acid signals activate this cellular growth switch.

26 Jul 2026

Time-restricted eating may help lower dementia risk in older women

Results from a small clinical trial suggest it may be possible to reduce your risk of dementia by eating during fewer hours of the day.

26 Jul 2026

FDA-issued sodium targets appear to have minimal impact

In 2021, the U.S. Food and Drug Administration (FDA) issued Phase I voluntary sodium reduction targets to encourage manufacturers to lower the amount of sodium in packaged food products by 2024.

25 Jul 2026

Engineered probiotic bacteria boost immune attack against pancreatic cancer

Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.

24 Jul 2026

Iowa State study identifies potential new target for leukemia treatment

In leukemia's most aggressive forms, the blood cell factories in our bone marrow falter. Instead of dividing and multiplying at their usual prolific pace, generating hundreds of billions of new cells daily, some precursor cells stall out at an immature stage.

24 Jul 2026

Inherited genetics can influence safety and success of CAR-T cell therapy

Chimeric antigen receptor (CAR)-T cell therapy, which reprograms an individual's immune cells to seek out and destroy certain cancer cells, has revolutionized treatment for blood cancers such as lymphoma.

24 Jul 2026