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Histamine boost helps the brain remember, decide, and learn from loss

Pitolisant, a histamine H3 receptor inverse agonist, improved recognition memory, working memory performance, and reinforcement learning in healthy adults. The findings suggest that histamine helps shape how the brain stabilizes new memories, accumulates evidence for decisions, and avoids overreacting to negative outcomes.

3 Jun 2026

Semaglutide boosts well-being among patients with diabetes and CKD

New findings from the landmark FLOW trial, presented at the 63rd ERA Congress, show that once-weekly semaglutide significantly improved health-related quality of life in adults with type 2 diabetes (T2D) and chronic kidney disease (CKD), equivalent to around eight additional days in full health per year.

3 Jun 2026

New all-oral regimen improves treatment convenience for AML patients

The ASCERTAIN V clinical trial demonstrated that an all-oral drug combination for older patients with acute myeloid leukemia (AML) is an effective alternative to the current standard, which requires repeated hospital or office visits for intravenous treatment.

3 Jun 2026

Novel CAR T treatment makes previously impossible kidney transplants possible

A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants.

3 Jun 2026

New protocol prevents heavy alcohol relapse after liver transplantation

In a study published in the Liver Transplantation journal by the American Association for the Study of Liver Diseases, Mayo Clinic researchers found that a new proactive treatment protocol for alcohol use disorder after liver transplant resulted in a 0% heavy alcohol relapse rate among patients who followed the protocol, compared with a historical relapse rate of approximately 25%.

3 Jun 2026

Study links rural living to worse epilepsy health outcomes

For people with epilepsy, living in counties that are more rural was associated with poorer health outcomes than for people living in more urban counties, according to a study published June 3, 2026, in Neurology, the medical journal of the American Academy of Neurology.

3 Jun 2026

Higher genetic pulse pressure risk associated with dementia-related mortality

When looking at genetic variants in a person's DNA that predispose them to disease, a new study has found having a higher number of genetic variants for increased pulse pressure is associated with a small, increased risk of dementia as a contributing cause of death.

3 Jun 2026

Constipation may be tied to more than discomfort

Constipation was associated with approximately twofold higher odds of depression in a meta-analysis of 18 observational studies involving 730,263 participants. The findings support integrated gastrointestinal and mental health assessment, especially for adolescents and young adults, while emphasizing that causality cannot yet be established.

3 Jun 2026

What pregnancy reveals about a woman’s future heart health

Pregnancy acts as a natural cardiovascular stress test, revealing hidden heart disease and identifying women at higher long-term risk after complications such as preeclampsia, gestational diabetes, and preterm birth. The review highlights major evidence gaps in cardio-obstetric care and calls for stronger postpartum screening, dedicated women’s health clinics, and better inclusion of reproductive-age women in research.

3 Jun 2026

Could GLP-1 drugs help prevent breast cancer? New study points to a possible link

A large retrospective cohort study of 111,646 overweight or obese women found that GLP-1 agonist exposure was associated with lower breast cancer incidence. After propensity-score matching, GLP-1 exposure was linked to nearly 30% lower odds of breast cancer, but the authors stress that randomized trials are needed before these drugs can be considered for prevention.

3 Jun 2026

Study potentially opens a new route to more selective cancer drug design

Researchers at the Icahn School of Medicine at Mount Sinai have identified a previously hidden druggable site in a cancer-related protein that could open the door toward the development of a new generation of more precise cancer drugs.

3 Jun 2026

New study reevaluates stroke risk for female patients with atrial fibrillation

A new Tulane University study challenges a long-standing assumption in heart care: that being female automatically increases stroke risk for patients with atrial fibrillation, a common condition that causes the heart to beat irregularly.

3 Jun 2026

Study shows how TAF1 regulates ferroptosis in cancer cells

Ferroptosis has become a promising area in cancer research because it may provide a way to target tumor cells that evade other better-known forms of programmed cell death, such as apoptosis and necroptosis.

3 Jun 2026

New technique protects pancreatic islet transplants without immunosuppressive drugs

Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood sugar levels.

3 Jun 2026

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.

3 Jun 2026

Continuing gout therapy during remission lowers future flare risk

The European Alliance of Associations for Rheumatology - held its 2026 annual Congress in London, where gout was high on the agenda.

3 Jun 2026

Brain tumor removal may improve blood sugar in diabetes patients

A new study published today in JAMA Network Open found that removing olfactory groove meningioma - a type of brain tumor located near the base of the brain - may improve blood sugar control in patients with diabetes.

3 Jun 2026

Simple probiotic may treat acid reflux and prevent cancer

Patients with acid reflux, which occurs when stomach acid pushes up into the esophagus, know the symptoms all too well: heartburn, belching, chest pain and trouble swallowing.

3 Jun 2026

American Heart Association launches national heart transplant research network

Nearly 60 years after the first successful heart transplant, the American Heart Association, a relentless force changing the future of health for everyone everywhere, is launching a bold new initiative to fundamentally transform how heart transplant care is delivered across the United States - addressing long-standing gaps in innovation, equity and patient outcomes.

3 Jun 2026

Engineered Salmonella delivers cancer-fighting viruses to deep tumors

Researchers at the University of Massachusetts Amherst have designed non-toxic Salmonella bacteria to deliver viruses that are safe to humans but potent against liver and pancreatic cancer tumors - two cancers with an extremely poor prognosis.

3 Jun 2026