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Lactylation may drive pulmonary fibrosis through metabolic reprogramming pathways

Announcing a new article publication in BIO Integration. Pulmonary fibrosis (PF) is a progressive and irreversible interstitial lung disease that is characterized by destruction of alveolar architecture, excessive proliferation of fibroblasts, and aberrant deposition of extracellular matrix (ECM) but the precise pathogenesis has yet to be fully elucidated.

27 May 2026

Vaginal bromocriptine may ease pain and heavy bleeding in adenomyosis

A pilot randomized controlled trial found that vaginal bromocriptine reduced menstrual bleeding, pelvic pain, menstrual duration, and cycle irregularity in women with adenomyosis compared with routine treatment.

27 May 2026

Study finds lower Alzheimer’s pathology in Black and Hispanic patients

A large multisite study of older people with cognitive impairment finds that Black and Hispanic people, while known to be far more apt to have dementia, are significantly less apt than other racial and ethnic groups to show Alzheimer's pathology on brain scans.

27 May 2026

Major trial compares surgical approaches for treating Chiari malformation and syringomyelia

A nationwide study has shed new light on how to most effectively and safely treat Chiari malformation and syringomyelia, rare neurological diseases that impact both children and young adults.

27 May 2026

Smartwatch seizure detection app may help reduce epilepsy-related deaths

In people with epilepsy, a new study has found a smartwatch application accurately detected tonic-clonic seizures, seizures with major convulsions, with a low rate of false alarms.

27 May 2026

Ghrelin rises in depression despite obesity’s usual appetite-hormone suppression

Researchers found that both acylated and deacylated ghrelin were elevated in unmedicated adults with major depressive disorder and obesity compared with non-depressed adults with obesity. The cross-sectional findings suggest ghrelin-system dysregulation may be linked to depression in obesity, but larger longitudinal studies are needed to test whether ghrelin is a reliable biomarker.

27 May 2026

Heart health before pandemic influenced severity of COVID-19 infections

Better heart health before the pandemic was linked to a lower risk of severe COVID-19 events, according to research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

27 May 2026

True toll of long COVID may be double that of current estimates, research shows

The true toll of long COVID may be double that of current estimates and hidden from current surveillance systems that rely on capturing diagnostic codes, according to new research led by Mass General Brigham.

27 May 2026

Persistent gut microbiome changes linked to sustained colorectal cancer risk

More than a decade after removal of an adenoma-a precancerous mass-from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer (CRC), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

27 May 2026

Degrading mutant KRAS protein induces greater lung cancer regression

KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.

27 May 2026

Prenatal therapy for cystic fibrosis improves lifelong health outcomes

This Cystic Fibrosis Awareness Month, Children's Hospital Colorado (Children's Colorado) is highlighting a growing shift in care: starting cystic fibrosis treatment before birth to improve lifelong health outcomes and reduce hospital stays.

27 May 2026

Study reveals how immune cells alter vascular plaque formation

A new LMU study shows how differently immune cells influence the formation of dangerous vascular deposits - and identifies miR-147 as a potential starting point for future therapies.

27 May 2026

Virtual reality navigation deficits predict future brain volume loss

Alzheimer's disease (AD) often begins long before it is clinically recognized, with subtle brain changes emerging years before noticeable memory loss or cognitive decline.

27 May 2026

NCCN launches a free service for updates on clinical cancer guidelines

The National Comprehensive Cancer Network (NCCN)-the nonprofit alliance of leading cancer centers responsible for essential NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) that providers rely on worldwide-has launched a new, free service.

27 May 2026

Naturally occurring peptide can reverse drug resistance in melanoma

Melanoma is one of the deadliest forms of skin cancer, due in large part to its ability to rapidly develop resistance to treatment.

27 May 2026

New colorectal cancer screening guidelines emphasize advanced stool tests

With colorectal cancer a growing concern among younger people, the American Cancer Society has endorsed two new types of stool tests to encourage people to get screened while also recommending a limited role for new blood tests many patients find appealing.

27 May 2026