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Orexo and SVF Vaccines collaborate to explore AmorphOX® formulation of LNP-mRNA vaccines

Orexo AB and SVF Vaccines AB today announced a research collaboration to investigate whether Orexo’s proprietary powder-based drug delivery technology, AmorphOX®, can be used to develop stable powder-based formulations of lipid nanoparticle (LNP)-encapsulated messenger RNA (mRNA) vaccines.

12 Nov 2026

Richmond Pharmacology highlights encouraging first-in-human results for Regeneron's investigational RNAi therapy in MASLD

Richmond Pharmacology, a specialist early-phase clinical research organization, has announced encouraging results from a first-in-human clinical trial evaluating CIDEBsiRNA, an investigational RNA interference (RNAi) therapy developed by Regeneron Pharmaceuticals, Inc.

12 Nov 2026

Researchers associate personality shifts with frontotemporal dementia functional decline

Frontotemporal dementia often results in early changes in personality or behavior before changes in cognitive skills.

12 Nov 2026

Beyond food: Bran-based gels show potential for targeted drug delivery

When it comes to colon health, the benefits of wheat and rye bran in wholegrain foods are well-known. Now researchers in Sweden have shown how these fibers may have a therapeutic use, too.

12 Nov 2026

Study decodes combinatorial p53 modification networks

A recent review highlights that p53 activity is orchestrated by a combinatorial network of post-translational modifications (PTMs), in which writers, erasers and reader proteins dynamically shape protein stability, DNA binding, subcellular localization, co-regulator assembly and transcriptional output.

12 Nov 2026

Meta analysis quantifies annual Alzheimer's incidence in type 2 diabetes

A Curtin University-led review has revealed type 2 diabetes significantly raises risk of developing Alzheimer's disease.

12 Nov 2026

New method reveals how individual glioblastoma cells spread through the brain

By combining live imaging of brain tissue with artificial intelligence, researchers at Uppsala University have developed a method that reveals how individual glioblastoma cells spread through the brain, how they can switch between different ways of moving, and how they are affected by cancer treatments. An

12 Nov 2026

Type 2 diabetes accelerates jawbone loss and causes tooth loss

Type 2 diabetes (T2D) is a chronic metabolic disorder whose global burden continues to rise. Beyond its systemic effects, T2D compromises skeletal health and markedly worsens loss of alveolar bone—the bone that anchors teeth—leading to tooth loosening, increased mobility, and eventual tooth loss.

11 Nov 2026

BNP hormone may actively promote blood clot formation, study finds

A hormone found in the blood and long viewed as a biological "check engine light" may do more than signal cardiovascular distress, according to researchers with the Texas A&M University Irma Lerma Rangel College of Pharmacy at Texas A&M Health.

11 Nov 2026

New statement highlights urgent need to improve veterans' heart health

Fewer than 5% of U.S. military veterans may achieve optimal cardiovascular health based on the American Heart Association's Life's Essential 8™ metrics, highlighting an urgent opportunity to improve prevention and help veterans live longer, healthier lives, according to a new scientific statement published today in the Association's flagship journal, Circulation.

11 Nov 2026

New molecular approach shows promise against treatment-resistant prostate cancer

Many modern cancer drugs typically target a specific protein or signaling pathway to treat tumors.

11 Nov 2026

Rare genetic mutation may protect against Parkinson's and Lewy body dementia

A rare genetic mutation may protect against developing Parkinson's disease and Lewy body dementia, a new study from researchers at Oregon Health & Science University suggests.

11 Nov 2026

Chronic stress promotes oral cancer through a brain–immune pathway

Chronic psychological stress is increasingly recognized as a risk factor for cancer, but how the brain communicates with the immune system to promote tumors has remained unclear.

11 Nov 2026

Exercise benefits people with chronic disease, but does the type matter?

A meta-analysis of 48 studies found that physical activity improved several chronic disease-related health indicators, particularly blood pressure, heart rate, and cardiorespiratory fitness, with significant benefits among people with hypertension and diabetes. Aerobic exercise had the strongest statistical evidence in the primary analysis, but no exercise type proved superior, and substantial variation between studies limited the certainty of the findings.

11 Nov 2026

Researchers identify previously unknown cause of fatal newborn brain disorder

Researchers at King Abdullah University of Science and Technology (KAUST) and King Faisal Specialist Hospital and Research Center (KFSHRC) identify a previously unknown cause of a fatal newborn brain disorder, giving long-awaited answers to families whose children were affected by the disease.

11 Nov 2026

Oral leukemia therapy offers effective at-home care for older adults

For years, older patients with acute myeloid leukemia-an aggressive cancer of the blood and bone marrow-have needed clinic injections five to seven days a month, plus a daily oral pill. For these older patients, that clinic schedule can be quite demanding.

11 Nov 2026

Case report highlights urgent communication gaps for deaf NHS patients

Deaf patients get a raw deal in NHS hospitals, suggests an illustrative case history of a deaf person's experience as an inpatient, published in the online journal BMJ Case Reports.

11 Nov 2026

Blocking serotonin receptors makes eye cancer cells sensitive to drugs

By studying G protein–coupled receptor (GPCR) signaling in a range of uveal melanoma cell lines, Jenna Aumiller and colleagues have discovered a way to make these cells more sensitive to compounds that inhibit cancer-linked (or oncogenic) signaling pathways.

11 Nov 2026

New study links senior living arrangements to mental health outcomes

As traditional multigenerational households have become less common, increasing numbers of older adults are living alone or with only their spouses.

11 Nov 2026

Scientists explore brain networks behind visual hallucinations and migraine with aura

Lancaster scientists are pioneering new approaches to understanding and influencing the brain networks behind the unusual visual hallucinations and distortions experienced in migraine with aura - and even by people without the condition.

11 Nov 2026