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A study links a blood protein to memory and brain changes in Down syndrome

Researchers studying 88 adults with Down syndrome and 43 controls estimated that serum β-synuclein increased approximately two decades before expected Alzheimer’s symptoms, preceding changes in other blood biomarkers. Higher levels correlated with poorer memory and brain changes, but the cross-sectional study could not distinguish whether the earliest increase reflected Alzheimer’s-related synaptic dysfunction, trisomy 21-related neurobiology, or both.

11 Oct 2026

Blood proteins may offer new clues to gut health in celiac disease

Celiac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.

10 Oct 2026

New project aims to test a protein-based therapy for Fragile X syndrome

A new research project at the University of California, Riverside, has received funding to investigate whether a novel protein-based therapy can correct abnormal brain activity associated with Fragile X syndrome.

9 Oct 2026

Routine blood test may offer clues to future dementia risk

A common blood test already carried out during routine health checks may contain clues about a person's long-term risk of dementia, according to research being presented at the ECNP Congress in Munich and recently published in the Journal of Alzheimer's Disease.

9 Oct 2026

Friends of BrainHealth grants advance dementia prevention and brain health research

For nearly 20 years, the Friends of BrainHealth donor circle has helped turn promising ideas into innovative brain health research.

9 Oct 2026

Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsy

A recent study from Johns Hopkins Medicine reveals that both the liver and brain contribute pathways to differing symptoms of the same rare inherited disorder.

9 Oct 2026

Global cardiac rehabilitation access stagnates despite rising cardiovascular disease

Despite rising incidents of cardiovascular disease (CVD), along with evidence that cardiac rehabilitation programs improve outcomes for those living with CVD, availability of these programs has not increased worldwide in the past decade, according to a new study by York University researchers.

9 Oct 2026

Molecular regulator CA8 may offer new therapeutic target for type 2 diabetes

Maintaining healthy blood glucose levels involves striking a balance between the glucose produced by the liver during fasting, and the insulin released from pancreatic beta cells after meals.

9 Oct 2026

New project aims to predict early protein dysfunction in neurodegenerative diseases

Neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS and Huntington's are associated with proteins that can change shape, stick together and eventually damage cells.

9 Oct 2026

Masked high blood pressure linked to higher risk of falls in older adults

Masked high blood pressure in adults older than age 78 is associated with a 70% higher risk of falls compared to high blood pressure readings in the office and at home among peers, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.

9 Oct 2026

New immune aging map helps decode future chronic disease risks

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

9 Oct 2026

Late-night snacking may affect liver health

New research led by Oregon Health & Science University suggests you should think twice about indulging in a late-night snack if you'd like to preserve liver health.

9 Oct 2026

Sutter Health care model safely expands local Alzheimer's treatment

A multidisciplinary care model developed across Sutter Health helped general neurologists address a practical challenge facing health systems nationwide: how to safely offer newer Alzheimer's disease treatments in community settings to more patients.

9 Oct 2026

Polymeric nanomedicine strategies improve solid tumor immunotherapy outcomes

Solid tumors are not merely collections of malignant cells but complex ecosystems comprising tumor cells, stromal cells, and the extracellular matrix (ECM).

9 Oct 2026

FDA approves atezolizumab combination for stage III colon cancer with deficient DNA mismatch repair

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has approved the immunotherapy drug atezolizumab (Tecentriq) in combination with fluoropyrimidine and oxaliplatin chemotherapy, for the adjuvant treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

9 Oct 2026

Study explains why cancer immunity declines faster in males

Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and Tim Padera, PhD, currently of the Mass General Brigham Cancer Institute, are the lead and senior authors of a paper published in Nature Aging, "Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age."

9 Oct 2026

Early-onset Alzheimer's patients accumulate symptoms years before diagnosis

People who develop Alzheimer's disease before the age of 65 experience a growing range of health problems and increasing use of healthcare services years before diagnosis.

9 Oct 2026

Lynch syndrome patients rarely use aspirin for cancer prevention

According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer - even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice.

9 Oct 2026

Brain injuries change how the hypothalamus responds to stress

Researchers from the Department of Cell Biology, Genetics and Physiology at the University of Malaga have led an international scientific team that has studied how a traumatic brain injury caused by a severe blow to the head conditions the brain's long-term response to subsequent stress situations.

9 Oct 2026