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GLP-1 treatments may reduce knee replacement surgery rates

GLP-1 receptor agonist drugs, used for the treatment of diabetes, and more recently, weight loss, are associated with a significantly lower long term risk of knee replacement surgery as a result of osteoarthritis, finds an analysis of medical records data, published in the open access journal Regional Anesthesia & Pain Medicine.

2 Jun 2026

New PET imaging approach quantifies synaptic pathology in multiple sclerosis

A new PET imaging approach that measures synaptic density in the spinal cord provides a quantitative way to assess the brain's functional wiring in patients with multiple sclerosis.

2 Jun 2026

New PET imaging platform improves osteosarcoma surgery precision

A new end-to-end PET imaging approach for osteosarcoma can rapidly and reliably distinguish tumor tissue from normal tissue and accurately assess surgical margins in real time.

2 Jun 2026

Three-drug strategy forces pancreatic tumors into lasting regression

A triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing.

2 Jun 2026

Is any level of alcohol safe? Major review reveals where drinking risks rise

This Burden of Proof review found that alcohol consumption is associated with higher risks for several cancers, liver disease, pancreatitis, lower respiratory infections, tuberculosis, and atrial fibrillation. Although low-to-moderate drinking showed modest observational links with lower risks of type 2 diabetes, dementia, and some cardiovascular outcomes, the evidence was weaker and potentially biased.

2 Jun 2026

New funding supports cutting-edge research to combat cancers across South Texas

The University of Texas at San Antonio (UT San Antonio) and its academic health center, UT Health San Antonio, recently received over $2.7 million in new academic and prevention awards from the Cancer Prevention and Research Institute of Texas (CPRIT) to further its mission of combating cancers across South Texas.

2 Jun 2026

AI-assisted model based on blood proteins could help predict retinal degeneration in diabetics

An AI-assisted model based on 71 different blood proteins could help doctors better predict retinal degeneration in diabetic patients before symptoms occur, according to a study published June 2nd in the open access journal PLOS Medicine by Huangdong Li from the Guangdong Provincial Clinical Research Center for Ocular Diseases in Guangzhou, China, and colleagues.

2 Jun 2026

Modified stem cell therapy reverses new-onset Type 1 diabetes in mice

A group of researchers at the Medical University of South Carolina (MUSC) has recently developed a new stem cell therapy with a remarkable ability to reverse new-onset Type 1 diabetes (T1D) in a mouse model of the disease.

2 Jun 2026

Study finds serious blood-related side effects associated with antibody-drug conjugates

A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies.

2 Jun 2026

First-in-class cancer drug gamitrinib evaluated in phase 1 clinical trial

Cancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse."

2 Jun 2026

City of Hope sets new standard for lifelong, research-driven cancer survivorship care

Supporting the growing number of Americans living with cancer has become one of the most urgent challenges in modern cancer care as more people live years or decades beyond a diagnosis.

2 Jun 2026

Machine learning tool predicts financial toxicity for cancer patients

Researchers at MUSC Hollings Cancer Center have developed a machine learning tool to identify cancer patients who may be at high risk for financial toxicity – the financial stress and hardship that can accompany a cancer diagnosis and treatment.

2 Jun 2026

Microenvironmental CTHRC1 protein promotes colorectal cancer tumor growth

A new research paper was published in Volume 17 of Oncotarget on May 20, 2026, titled "Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer."

2 Jun 2026

Allen Institute launches global research initiative to accelerate new treatments for brain disorders

The Allen Institute, together with partner organizations, today launched the Brain Health accelerator: an ambitious global research initiative seeking to identify the specific brain cells and circuits affected in neurodegenerative disease and other brain disorders and use that knowledge to accelerate the development of new treatments.

2 Jun 2026

Cannabis and tobacco co-use lowers cognitive performance in at-risk youth

New research shows that among people at clinical high risk for psychosis, cannabis and tobacco co-use was associated with lower cognitive performance compared to healthy controls.

2 Jun 2026

Stem cell transplantation is the most cost-effective sickle cell treatment

Stem cell transplantation is the most cost-effective option for long-term care of sickle cell disease in adults when compared with gene therapy and standard of care treatment, according to new research published in Blood.

2 Jun 2026

Heart failure therapy referrals vary widely across the United Kingdom

Substantial variations in referrals for advanced heart failure therapies are apparent across the UK and Ireland, with no obvious link to geographical location or social deprivation to explain the findings, reveals the first national audit of its kind, published online in the open access journal Open Heart.

2 Jun 2026

How dysregulated collagen IV homeostasis causes cerebral microbleeds

Millions of older adults have tiny brain hemorrhages called cerebral microbleeds, which are strongly associated with dementia, cognitive decline, and stroke.

2 Jun 2026

Late sleepers experience higher anxiety driven by severe nocturnal loneliness

A new study to be presented at the SLEEP 2026 annual meeting found that individuals with an evening chronotype, who prefer to go to sleep and wake up at later times, report poorer mental health, higher general loneliness, and higher nocturnal loneliness.

2 Jun 2026

Magnetic microrobots deliver stem cells to heal spinal cord injuries

A research team from ETH Zurich and the University of Zurich (UZH) has developed a novel approach to treating spinal cord injuries: controllable microrobots deliver stem cells directly to the site of an injury, where they promote nerve cell regeneration.

2 Jun 2026