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Researchers show how ketamine fights difficult-to-treat depression

The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression.

31 May 2020

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

A new meta-analysis published on the preprint server medRxiv by the researchers from the United States and Greece reveals that the likelihood of death is 65% higher in hospitalized coronavirus disease (COVID-19) patients with diabetes when compared to non-diabetics – urging the adequate glucose control in the era of the pandemic.

31 May 2020

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Results of the NRG Oncology phase III clinical trial NRG-GY004 indicated that the addition of the investigational agent cediranib to olaparib and standard platinum-based chemotherapy did not improve progression-free survival (PFS) outcomes for women with platinum-sensitive ovarian cancer; however, activity between the treatments was similar in patients.

30 May 2020

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

A new type of immunotherapy treatment for metastatic non-small cell lung cancer (NSCLC) is being tested by Missak Haigentz, Jr., MD, medical director of hematology and oncology for Atlantic Health System.

30 May 2020

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of patients with a specific subtype of advanced bowel cancer, when compared with chemotherapy.

30 May 2020

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

A harmonization of 'big data' in examining long-term outcomes with contemporary treatment for pediatric and adult Hodgkin lymphoma patients is yielding a new approach to inform future clinical trial design and enhance clinical decision-making.

30 May 2020

New review analyzes appropriateness of off-pathway cancer care

Clinical oncology pathways are an important tool, helping cancer care providers and their patients to zero in on the most appropriate care plan.

30 May 2020

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs.

30 May 2020

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

Results of an Electronic Health Record (EHR) study assessing the most commonly used medications for raising blood pressure in patients with nontraumatic subarachnoid hemorrhage (SAH), a rare type of stroke, have been published in Neurosurgical Focus by scientists at The University of Texas Health Science Center at Houston (UTHealth).

30 May 2020

Expert offers COVID-19 guidance for patients with COPD

Chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema, is a chronic lung disease that makes it hard to breathe. The disease affects millions of Americans and is the fourth leading cause of disease-related death in the U.S. People with COPD have a higher risk of more severe illness from COVID-19 due to their existing lung problems.

30 May 2020

Toshiba and Shinshu University jointly develop a 'tumor-tropic liposome technology' for gene therapy

Toshiba Corporation and a team led by Professor Yozo Nakazawa at the Department of Pediatrics, Shinshu University, have together developed a “tumor-tropic liposome technology” for gene therapy. The technology uses unique, nano-sized biodegradable liposomes developed by Toshiba to accurately and efficiently deliver therapeutic genes to targeted cancer cells, and achieves safer gene delivery than viruses used as carriers.

30 May 2020

First-ever oncology hospital-at-home program shows improved patient outcomes

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) presented the first outcomes evaluation of an adult oncology hospital-at-home program today at the 2020 American Society of Clinical Oncology (ASCO) annual meeting.

30 May 2020

Researchers design developmental map of sound-sensing structure in mice’s inner ear

A team of researchers has generated a developmental map of a key sound-sensing structure in the mouse inner ear.

30 May 2020

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

While breakthrough treatments have emerged for several cancers over the last two decades, driving striking improvements in survival and other clinical outcomes, too little is known about the risk of therapy-related hematologic cancers following targeted and immunotherapeutic approaches.

29 May 2020

First-ever oncology hospital-at-home program improves patient outcomes, reduces hospitalizations

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) presented the first outcomes evaluation of an adult oncology hospital-at-home program today at the 2020 American Society of Clinical Oncology annual meeting.

29 May 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Using functional MRI to demonstrate neural suppression in autism

According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity.

29 May 2020

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Patients with advanced non-small cell lung cancer (NSCLC) and the MET exon 14 (METex14) skipping mutation had a 46.5% objective response rate to the targeted therapy drug tepotinib, as shown in a study published today in the New England Journal of Medicine and presented at the 2020 American Society of Clinical Oncology Annual Meeting ASCO20 Virtual Meeting (Abstract 9556 - Poster 322) by researchers from The University of Texas MD Anderson Cancer Center.

29 May 2020

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Medical Condition News

Researchers show how ketamine fights difficult-to-treat depression

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

Developing an international consortium to improve clinical decision-making in Hodgkin lymphoma

New review analyzes appropriateness of off-pathway cancer care

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

Expert offers COVID-19 guidance for patients with COPD

Toshiba and Shinshu University jointly develop a 'tumor-tropic liposome technology' for gene therapy

First-ever oncology hospital-at-home program shows improved patient outcomes

Researchers design developmental map of sound-sensing structure in mice’s inner ear

Newer treatment approaches may reduce risk of therapy-related hematologic cancers

First-ever oncology hospital-at-home program improves patient outcomes, reduces hospitalizations

High-throughput analysis of blood plasma could help identify biomarkers for ALS

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Using functional MRI to demonstrate neural suppression in autism

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

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