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Researchers have identified a protein called HIF-2a, which is important in retina formation

Hoping to prevent blindness in premature babies, UT Southwestern Medical Center researchers have identified a protein that responds to oxygen levels in cells and tissues and also affects the developing eye.

22 Feb 2005

2.5 million euros helps fight liver cancer

The overall project will concentrate on three areas where Europe is in a relatively favourable position compared with the US - human tissue resources, ribonucleic acid (RNA) technology, and structural proteomics. However, the initial focus will be on the development of genomics targets in hepatocellular carcinoma (HCC) or liver cancer as it is one of the leading causes of cancer death worldwide and has a very poor prognosis.

22 Feb 2005

Lack of magnesium in diet linked to disease

The Gordon Research International Conference on Magnesium was held during the second week in February in Ventura, California, to discuss the research findings on the links between deficiencies in the mineral magnesium and a host of life-threatening diseases, including heart disease and arteriosclerosis.

22 Feb 2005

Secreted signaling protein called Wnt10b secret to new drugs for preventing or treating osteoporosis

Leaping tall buildings in a single bound may be out of the question, but the genetically engineered "supermice" in Ormond MacDougald's laboratory at the University of Michigan Medical School are definitely stronger than average.

22 Feb 2005

Why some lung cancers stop responding to the drugs erlotinib (Tarceva) and gefitinib (Iressa)

Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) have found an explanation for why some lung cancers stop responding to the drugs erlotinib (Tarceva) and gefitinib (Iressa).

22 Feb 2005

Stop-smoking products increase quit rate for smokers who need to quit the most

An article in the current issue of the Journal of Substance Abuse Treatment (Volume 28, Issue 1, 2005) provides new hope for smokers who are highly dependent upon tobacco and who smoke more than two packs per day.

21 Feb 2005

Crystallized molecular machine reveals possible new paths for treating diseases

The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients.

21 Feb 2005

New clues to amyloidoses

Familial amyloid polyneuropathy (FAP), a hereditary disease characterised by abnormal deposits of insoluble protein in the organs, results from a mutation in a single gene (the transthyretin or TTR gene). Nevertheless, disease incidence and age of onset can vary significantly between patients what have always puzzled scientists.

21 Feb 2005

Lack of collagen increases likelihood of osteoarthritis

Duke University Medical Center researchers have found that joints whose cartilage lacks a specific type of collagen will develop osteoarthritis – the so-called "wear-and-tear" form of the disease – at a greatly accelerated rate.

20 Feb 2005

Exercise and dietary changes vital in taking and keeping off weight that is associated with many chronic health problems

When the National Academy of Science’s Institute of Medicine recently announced that Americans should exercise an hour a day to fight the country’s growing obesity epidemic, collective groans could be heard in big cities and small towns everywhere.

20 Feb 2005

Pitt researcher presents findings on when to accept organ transplants

A transplant is the only option for someone with end-stage liver disease, but patients face difficult questions when choosing the best time to receive a transplant.

20 Feb 2005

Better ways to heal and regenerate bones using microcomputed tomography imaging

Tissue engineers can choose from a wide range of living cells, biomaterials and proteins to repair a bone defect. But finding the optimum combination requires improved methods for tracking the healing process.

20 Feb 2005

Beta blocker lowers blood pressure and wards off repeat heart attacks

A form of beta blocker, a drug commonly used to lower blood pressure and ward off repeat heart attacks, may provide the answer to preventing osteoporosis, said a Baylor College of Medicine researcher.

20 Feb 2005

New bone marrow model could help people with sickle cell disease

A new model showing how sickle cell blood cells operate within bone marrow is presented at a conference in Austria today. Researchers at Imperial College London, who developed the model, hope that it will eventually be used by clinicians to advance more effective treatments for sickle cell disease.

20 Feb 2005

Genetic signature that can identify breast cancer patients at high risk of distant recurrence

Researchers have discovered a genetic signature that can identify breast cancer patients at high risk of distant recurrence, reporting their results in this week’s issue of The Lancet.

20 Feb 2005

Air pollution thickens the blood and boosts inflammation

Air pollution, and especially particulate matter, thickens the blood and boosts inflammation, finds experimental research in Occupational and Environmental Medicine.

20 Feb 2005

Cannabis use may increase risk of stroke

Regular users of cannabis could be putting themselves at risk of stroke, while they are still young, indicates a case report, published in the Journal of Neurology Neurosurgery and Psychiatry.

20 Feb 2005

Quetiapine speeds up rate of decline in Alzheimers

Quetiapine, a drug commonly used in nursing homes to treat agitation and related symptoms in people with Alzheimers' disease actually worsens patients' illness, speeding up their rate of decline significantly, says a paper published on bmj.com.

20 Feb 2005

Massachusetts support of stem cell research

The Massachusetts Medical Society, the statewide association of physicians with some 18,000 members, has offered testimony before the Joint Committee on Economic Development and Emerging Technologies in support of Senate Bill 25, An Act Promoting Stem Cell Research.

17 Feb 2005

Are hormone therapy drugs safe?

The history of hormone therapy drugs – once thought of as almost magic pills to keep women healthy, vital and young – shows why it is so important to conduct research studies to identify the risks and benefits of drugs, say researchers from Wake Forest University Baptist Medical Center.

17 Feb 2005