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Urine-based microRNA clock predicts biological aging without a blood test

Researchers developed and validated a non-invasive urinary microRNA aging clock using extracellular vesicle miRNAs from more than 6,000 adults. The model predicts age with about 4 to 5 years error and links accelerated aging signals to type 2 diabetes.

16 Dec 2025

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Chronic breathlessness drives longer hospital stays and higher healthcare costs

Chronic breathlessness, a symptom often overlooked by healthcare systems, is associated with longer lengths of hospital stay on already overstretched healthcare resources, says new Flinders University research.

16 Dec 2025

Salutogenic microbes offer new pathways to better health

Viruses and bacteria get a bad rap around the world but now Flinders University experts are identifying the positive 'upside' of powerful benefits that microbes have on human health.

16 Dec 2025

Multiple biological systems show abnormalities in ME/CFS patients

New Australian research has identified simultaneous abnormalities across multiple biological systems in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

16 Dec 2025

Rapid adoption of AI in primary care raises safety concerns

From digital scribes to ChatGPT, artificial intelligence (AI) is rapidly entering GP clinics. New University of Sydney research warns that technology is racing ahead of safety checks, putting patients and health systems at risk.

16 Dec 2025

Poor housing conditions harm children’s school attendance and grades

Children living in substandard housing in England miss 15 more school days and achieve worse test scores in English and maths than their peers living in better quality housing, suggests research published online in the Journal of Epidemiology & Community Health.

16 Dec 2025

Combined physical frailty and depression may sharply raise dementia risk

Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these 2 factors alone contributing around 17% of the overall risk, suggest the findings of a large international study, published in the open access journal General Psychiatry.

16 Dec 2025

Specific gut bacterium reduces weight gain and improves metabolic health

The gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.

16 Dec 2025

Alcohol-related liver disease deaths surge with widening socioeconomic gaps

Researchers at Saint Louis University School of Medicine say deaths from alcohol-related liver disease have surged in recent years, and the increase is hitting people without a college degree the hardest.

16 Dec 2025

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

16 Dec 2025

Blocking a key cell pathway reduces muscle wasting in pancreatic cancer

Researchers at the University of Houston are pushing the boundaries of biomedical innovation with a discovery that could transform treatment for one of cancer's most devastating complications.

16 Dec 2025

Researchers identify partner protein that supports appetite regulating-protein

A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to new research, and the findings could help researchers better understand genetic obesity.

16 Dec 2025

Lentilactobacillus kefiri can prevent and even reverse aging-related immune alterations

The process of aging is associated with a decline in immune functions and persistent low-level inflammation.

16 Dec 2025

Cannabis and nicotine co-use is widespread among young adults

Simultaneous use of cannabis with nicotine and tobacco products is common among cannabis users-particularly those who vape-according to a new study from Columbia University Mailman School of Public Health.

16 Dec 2025

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

University of Virginia School of Medicine researchers have uncovered how and why traumatic brain injury (TBI) increases the risk for Alzheimer's disease, and their work suggests a potential way to prevent that increased risk.

16 Dec 2025

Higher minimum drinking age linked to better grades and mental health

Despite a downward trend in alcohol consumption, drinking rates among European teenagers remain notably high by international standards.

16 Dec 2025

A multi-gene mouse model reveals new mechanisms of Hirschsprung disease

During development of the digestive system, a complex network of nerves forms around it, creating a "second brain" - the enteric nervous system (ENS) - which controls the movement of food and waste through the gut.

16 Dec 2025

Positive parenting reduces the risk of adolescent self-harm

Self-harm refers to intentionally injuring one's own body as a coping mechanism to emotional distress. It manifests in many forms and has serious consequences not only on physical health but also on mental health. Self-harm among adolescents is becoming a significant public issue.

16 Dec 2025

Revolutionary quantum sensors could enable earlier cancer diagnosis and treatment

A revolutionary quantum sensing project that could transform cancer treatment by tracking how immune cells interact with tumors has been awarded a prestigious £2 million Future Leaders Fellowship.

16 Dec 2025