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Study links methylglyoxal stress to immunotherapy resistance in triple-negative cancer

The metabolism of cancer cells may play a key role in their ability to evade the immune system. This is demonstrated by a new study conducted by researchers at the University of Liège, which reveals how methylglyoxal stress – a by-product of tumor metabolism – promotes immunosuppression and the formation of metastases, and may contribute to resistance to immunotherapy and the progression of triple-negative cancer.

9 Sep 2026

New genetic map helps track aggressive prostate cancer development

Prostate cancer is the second most common form of cancer among men globally. Yet, we still know relatively little about why the disease develops or why some men live with it for years while in others it progresses aggressively.

9 Sep 2026

Caloric restriction reduces genetic mutations across the mouse genome

Mutations are changes in the molecular "letters" that make up DNA, the genetic blueprint for cells. Mutations build up with age in every cell when DNA is damaged or when cells make mistakes in fixing or copying it.

9 Sep 2026

Skin microbiome changes may predict infant eczema and food allergies

The first clues that a baby may develop eczema or food allergies could be hiding in the microscopic organisms living on their skin, according to a study led by researchers in Washington State University's College of Veterinary Medicine.

9 Sep 2026

Standard pediatric blood pressure thresholds miss early trauma warning signs

Blood pressure thresholds commonly used to identify dangerously unstable vital signs in children may not signal trouble soon enough after a traumatic injury, according to a national study of more than 230,000 pediatric trauma patients.

9 Sep 2026

Ten minutes of slow running boosts brain function and mood

A growing body of evidence shows that exercise improves mood and cognitive function. However, much of this evidence comes from cycling, which allows researchers to precisely control exercise intensity in the laboratory.

9 Sep 2026

New study evaluates medical and surgical treatments for mitral regurgitation

Announcing a new article publication for Cardiovascular Innovations and Applications journal providing fresh evidence on the effectiveness of medical and surgical treatments for mitral regurgitation (MR).

9 Sep 2026

Single-cell atlas reveals key macrophage subtypes in myocardial infarction

Announcing a new article publication for BIO Integration. Myocardial infarction (MI) is characterized by extensive immune activation and dynamic remodeling of the cardiac microenvironment, in which myeloid cells play critical roles in regulating inflammation and tissue repair.

9 Sep 2026

Study shows how the microbiome shapes lung cancer immunotherapy outcomes

Despite the revolutionary impact of immune checkpoint inhibitors on cancer therapy, 60% to 80% of patients with NSCLC still show suboptimal responses.

9 Sep 2026

Weakened form of Mpox drove the 2022 global outbreak

The strain of Mpox behind the 2022 outbreak was a weakened form of the virus, which may have helped to spread it faster, a new study from the University of Surrey reports.

9 Sep 2026

New project explores financial impact of chronic kidney disease

A new research project launched by Kidney Wales and Aston University will explore how living with chronic kidney disease affects people's financial wellbeing.

9 Sep 2026

Updated COVID-19 vaccines protect adults with autoimmune rheumatic conditions

In an Arthritis & Rheumatology analysis of data on 60,980 US adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024, those who received booster or updated (2023-2024) COVID-19 vaccines were less likely to be hospitalized for COVID-19 compared to those who received only the initial series vaccines or who were unvaccinated.

9 Sep 2026

Digital program reduces burnout and anxiety in distressed nurses

Burnout, depression, anxiety, and suicide are increasing in the nursing and overall health care workforce, which adversely impacts health care quality and safety.

9 Sep 2026

Workplace stress may impair erectile function in young men

New research in the International Journal of Clinical Practice suggests that workplace psychological stress may impair erectile function in young men by affecting certain stress management pathways in the brain and reducing testosterone levels.

9 Sep 2026

Johns Hopkins researchers identify human resistin as a key driver of inflammation

Researchers at Johns Hopkins Medicine have uncovered a critical biological mechanism that helps explain how inflammation is triggered and sustained in a wide range of diseases-highlighting a promising avenue for future therapeutic development.

9 Sep 2026

Is stroke risk higher after a cancer diagnosis?

New research indicates that people with invasive cancer face an elevated risk of experiencing a stroke, especially in the first few months after diagnosis and especially if they have certain types of cancer.

9 Sep 2026

EpilepsyGTx and Viralgen collaborate to advance AAV gene therapy program for epilepsy ahead of first-in-human trial

EpilepsyGTx, a biotechnology company developing gene therapies for refractory epilepsy, and Viralgen, a leading contract development and manufacturing organization (CDMO) specializing in recombinant adeno-associated virus (AAV) gene therapies, today announced a partnership to support production of EpilepsyGTx's lead investigational gene therapy program targeting patients with focal refractory epilepsy (FRE), EPY201, ahead of first-in-human clinical trials.

From EpilepsyGTx 9 Sep 2026

Study uncovers cellular mechanisms behind long-lasting antibody responses

A team led by investigators from the University of Osaka uncovers cellular mechanisms that favor long-lived antibody responses, providing insights that may help researchers design vaccines that provide longer-lasting protection against infection.

9 Sep 2026

Non-nutritive sweeteners may aid sugar reduction without affecting weight or health

The review, led by Eva Marija Čad of the University of Ljubljana and Wageningen University & Research, alongside Professor Graham Finlayson of the University of Leeds and colleagues from other institutions in the Netherlands, Denmark, Spain and Belgium, was developed in connection with a 2025 webinar series hosted by the Institute for the Advancement of Food and Nutrition Sciences (IAFNS).

9 Sep 2026

Why a shorter eating window may not mean better metabolic health

In a nationally representative cross-sectional study of 16,973 Korean adults, researchers identified three distinct eating patterns based on the timing and distribution of daily energy intake. Eating later within a shorter daily window was associated with higher odds of metabolic syndrome, elevated blood pressure, triglycerides, and fasting glucose, while frequent grazing showed a mixed metabolic profile.

8 Sep 2026