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LEF1 and niche-derived factors regulate T cell stemness across chronic diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops.

1 Jul 2026

UC San Diego study reveals genetic causes of rare neuromuscular disorders

Scientists at the University of California San Diego have uncovered how genetic mutations cause a rare group of inherited neuromuscular disorders and identified promising new strategies to correct them, including a potential new use for an existing antidepressant.

1 Jul 2026

Fatty liver disease fuels aggressive metastatic colorectal cancer spread

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer.

1 Jul 2026

German study identifies therapeutic Achilles' heel for advanced colorectal cancer

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer.

1 Jul 2026

Ten weeks of cognitive rehabilitation reverses long Covid brain fog

Ten weeks of cognitive rehabilitation can help people with long Covid symptoms such as brain fog achieve their goals in returning to work and hobbies, finds a new clinical trial led by University College London (UCL) researchers.

1 Jul 2026

Biological heart valves support safer pregnancies despite reoperation risks

In severe disease of the aortic valve, choosing a new heart valve is especially difficult for young women who want to become pregnant.

1 Jul 2026

CAR-T cell therapy shows potential to eliminate aggressive glioblastoma

A study led by a researcher based at King's College London and McMaster University in Canada reveals how CAR-T cell therapy, a treatment that engineers a patient's own immune cells to recognize and attack cancer, could be used to treat glioblastoma.

1 Jul 2026

Prenatal paracetamol use does not increase child neurodevelopmental risks

Researchers from the University of Hong Kong (HKUMed), along with Aston Pharmacy School's Professor Ian Chi-Kei Wong, have shown that using paracetamol (acetaminophen) during pregnancy does not increase a child's risk of developing autism spectrum disorder (ASD) or attention‑deficit hyperactivity disorder (ADHD).

1 Jul 2026

Novel biomimetic peptide actively rebuilds damaged tooth dentin

Dentin hypersensitivity affects millions of people worldwide, yet existing treatments often provide only temporary relief.

1 Jul 2026

Alzheimer’s disease biomarkers predict rapid cognitive decline in very old adults

Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging.

1 Jul 2026

Scientists map how chronic stress alters somatostatin levels in the brain

Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that decides how fast a system is allowed to go.

1 Jul 2026

Cancer's biggest treatment challenge may be getting solved 250 miles above Earth

For more than two decades, precision oncology has been promoted as the future of cancer treatment, matching therapies to the unique biology of a patient's tumor.

1 Jul 2026

Genetic markers for ADHD influence early toddler activity levels

A toddler's activity levels are influenced by genetic differences, with some of the same genetic markers also linked to Attention Deficit and Hyperactivity Disorder (ADHD), according to new research from the University of Surrey.

1 Jul 2026

COVID-19 vaccine boosters may protect against future animal coronavirus outbreaks

COVID-19 vaccine boosters not only protect against SARS‑CoV‑2 – the virus behind the most recent pandemic – but may also help protect against some future coronaviruses that risk spreading from animals to humans, Cambridge researchers have shown.

1 Jul 2026

GLP-1 medications may improve long-term health for people with peripheral artery disease

GLP-1 receptor agonists (GLP-1 RA) medications were shown to reduce the number of deaths, amputations and hospitalizations among people with Type 2 diabetes who also had narrowed leg arteries associated with PAD (peripheral artery disease), according to new, independent research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

1 Jul 2026

Obesity may account for up to one in four polypharmacy cases

The study reveals obesity's role in polypharmacy, indicating that reducing obesity may lower medication burden and enhance quality of life for older adults.

1 Jul 2026

Genetics play a bigger role than pregnancy in childhood obesity risk

Genetic factors primarily explain the link between parental and childhood BMI, with maternal obesity impacting birth weight more than later childhood obesity.

1 Jul 2026

New soft robotic heart accurately mimics the complex movements of human valves

Researchers at UNSW Sydney have developed a fully synthetic soft robotic heart that reproduces the complex movements and internal structures of the human heart, opening the door to better treatments, safer medical devices and more personalized care.

1 Jul 2026

New AI framework outperforms conventional biomarkers in predicting cancer survival

Digestive system cancers, including hepatobiliary and gastrointestinal malignancies, remain a major global oncological burden. Although immune checkpoint inhibitors have changed the treatment landscape for some patients, their overall efficacy remains limited, with only about 15% to 30% of patients achieving durable clinical benefit.

1 Jul 2026

Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care

A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

1 Jul 2026