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One drink a day may be the new upper limit for safer alcohol guidance

A US cause-specific modeling study found no net protective health effect from low-level alcohol consumption, with lifetime alcohol-attributable mortality risk rising above 1 in 1,000 at just over 6.5 drinks per week for males and 7.0 drinks per week for females.

11 Jun 2026

A hidden immune pathway may help explain why Alzheimer’s inflammation persists

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.

11 Jun 2026

Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration

The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, neuronal stress, blood-brain barrier integrity, and type I interferon signaling. The review highlights why selective, context-dependent modulation of cGAS-STING could help treat neurodegenerative diseases, while preserving its essential roles in antiviral defense and tumor surveillance.

10 Jun 2026

Western diet weakens the gut’s nervous system through iron-dependent damage

A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.

10 Jun 2026

Low-methionine diet shows promise against aggressive brain tumors

An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.

10 Jun 2026

Researchers identify genetic cause of severe childhood lung disease

A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, which results in severe lung disease.

10 Jun 2026

Researchers uncover immune loop driving Sjögren's disease progression

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

10 Jun 2026

Many stroke patients miss intensive rehabilitation after hospitalization

Fewer than one in four people with stroke and fewer than one in seven people with traumatic brain injury receive inpatient rehabilitation care after being hospitalized, according to a study published on June 10, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

10 Jun 2026

Elevated blood pressure linked to lower dementia risk in people with physical frailty

For people with physical frailty, having high blood pressure may be associated with a lower risk of dementia, according to a study published on June 10, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

10 Jun 2026

Study identifies an important driver of inflammatory bowel disease

Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals NHS Foundation Trust, have identified an important driver of inflammatory bowel disease (IBD).

10 Jun 2026

More movement and less sitting benefit pregnant women

Women who engage in light physical activity and lessen their sedentary time may significantly reduce the risk of key health problems during pregnancy, according to a new University of Iowa-led study.

10 Jun 2026

Short-term fasting may reduce inflammation linked to gum disease

People who follow a short-term low-calorie diet may have reduced markers of inflammation associated with gum disease.

10 Jun 2026

Remote work explains part of the post-pandemic rise in mental distress

Researchers found that workers in remote jobs spent more time alone after the COVID-19 pandemic and experienced greater psychological distress than those in non-remote jobs. The effects were strongest among people living alone, suggesting that reduced everyday social contact may be an important cost of remote work.

10 Jun 2026

Silver nanoparticles enable precise DNA cutting and assembly

DNA is composed of long chains that act as the blueprint for living organisms. In genetic engineering, scientists cut DNA at specific sites and join the resulting fragments to other DNA sequences, enabling applications such as advanced crop breeding, genetic disease treatment, and the generation of animal models for drug discovery.

10 Jun 2026

Study links low vitamin C levels in the blood plasma to reduced brain connectivity

A study of 2,044 older Japanese adults found that those with lower vitamin C levels in their blood plasma tended to have a lower volume of gray matter in their brains, as well as lower connectivity amongst a collection of brain regions known as the default mode network.

10 Jun 2026

New study maps early genetic disruptions in Rett syndrome

To better understand what drives the emergence of symptoms in Rett syndrome, researchers at Baylor College of Medicine and the Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital took a closer look at brain cells in mice modeling Rett syndrome before symptoms appeared.

10 Jun 2026

Many middle-aged Americans lack basic health literacy

OK, Boomers, it turns out Millennials and Gen X also struggle navigating the often-confusing and overwhelming world of health care.

10 Jun 2026

Quality of life for working-age Japanese adults declines steadily

The COVID-19 pandemic upended many aspects of everyday life, including socialization, office work, and medical care, but little data was available to quantify how those changes affected quality of life both during the pandemic and over the long term, particularly on a national scale.

10 Jun 2026

Brain injury survivors face higher risk of brain cancer death

Daniel Daneshvar, MD, PhD, director of the HealthSpan Lab and Chief of the Department of Physical Medicine and Rehabilitation at Mass General Brigham, and Charlotte Luster, of the HealthSpan Lab, are the senior and lead authors of a paper published in Neuroepidemiology, "Brain Cancer Mortality following Traumatic Brain Injury (TBI): A TBI Model Systems Study."

10 Jun 2026

NIH awards $1 million five-year grant to study the genetics of cataracts in children

Jennifer Rossen, MD, a pediatric ophthalmologist at Ann & Robert H. Lurie Children's Hospital of Chicago, recently received a $1 million five-year grant from the National Institutes of Health/National Eye Institute (NIH/NEI) to study the genetics of cataracts in children.

10 Jun 2026