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Researchers uncover new mechanism linking metabolism, immunity, and skeletal health

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

25 Apr 2026

Email alerts boost valve replacement rates in older patients with aortic stenosis

New data finds older patients with severe aortic stenosis (AS) were more likely to receive aortic valve replacement (AVR) and survive when clinicians received automated email notifications with abnormal heart ultrasound results detecting AS.

25 Apr 2026

Study reveals high use of complementary health approaches in seniors

Researchers say the finding highlights the need for more evidence and better conversations about risks and benefits of mindfulness, yoga, tai chi, acupuncture, and other complementary health approaches.

25 Apr 2026

ISSCR urges NIH to continue support human embryonic stem cell research

The International Society for Stem Cell Research (ISSCR) has submitted a formal response to a Request for Information (RFI) issued by the National Institutes of Health (NIH) regarding its pause on new submissions to the NIH Human Embryonic Stem Cell (hESC) Registry and considerations to reduce reliance on hESCs in federally supported research.

25 Apr 2026

Scientists discover immune sentinel cells within skin hair follicles

Researchers at the School of Medicine at the University of California, Riverside have discovered previously unrecognized immune surveillance structures in the skin.

25 Apr 2026

Baby teeth reveal early metal exposure effects on brain

Researchers at the Icahn School of Medicine at Mount Sinai report that early-life exposure to common environmental metals may influence brain development and behavioral health more than a decade later.

25 Apr 2026

Scientists identify STING switch driving inflammation in Alzheimer’s disease

The brain has its own immune system, which detects threats and mounts a defense. A growing body of evidence has shown that in Alzheimer's disease, those immune cells are chronically overactivated, causing inflammation that damages the connections between brain cells.

24 Apr 2026

Media coverage and campaigns drove decline in youth vaping

Researchers from the University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science have found that both anti-vaping advertising and widespread news coverage of a lung-injury outbreak tied to vaping - known as e-cigarette or vaping product use-associated lung injury (EVALI) - were critical in making 2019 a turning point in youth vaping prevalence in the United States.

24 Apr 2026

Unraveling the mystery of cognitive resilience in aging brains

Some brains resist Alzheimer's, even when the disease is already present. Researchers at the Netherlands Institute for Neuroscience have found that this likely depends on how specific brain cells, known as immature neurons, respond to damage caused by the disease.

24 Apr 2026

New strategy boosts natural killer cells to fight cancer

Scientists have developed a strategy to boost the cancer-fighting power of natural killer (NK) cells, part of the immune system's first line of defense.

24 Apr 2026

New biorepository approach advances research on sudden cardiac arrest

A cutting-edge University of Cincinnati College of Medicine study has shown how emergency medicine researchers can partner with community emergency medical services nationwide to investigate the causes of sudden cardiac arrest.

24 Apr 2026

Trends reveal growing burden of deaths from non-ischemic cardiogenic shock

New data from the CDC WONDER database finds deaths from heart attack-related cardiogenic shock (CS) decreased between 1999 and 2020, but deaths linked to heart failure (HF) and abnormal heart rhythms have risen sharply since 2010, particularly among men.

24 Apr 2026

AI-assisted doctors perform better in complex clinical decision making

Artificial intelligence-powered chatbots are getting pretty good at diagnosing some diseases, even when they are complex.

24 Apr 2026

Genetic research identifies rare DNA changes causing common heart valve defect

New clues from genetic research may help explain what causes the most common heart defect present at birth.

24 Apr 2026

Lower grip strength in early pregnancy linked to risk of hypertensive disorders of pregnancy

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal mortality worldwide. In addition, HDP can lead to fetal growth restriction, preterm birth, and various long-term adverse health outcomes.

24 Apr 2026

Elevated Lp(a) levels associated with residual cardiovascular risk

New data analyzing more than 20,000 patients from three major NIH studies show that elevated Lipoprotein(a) [Lp(a)] is associated with residual cardiovascular risk and warrants aggressive risk reduction.

24 Apr 2026

M-TEER procedure effectively treats mitral regurgitation in patients with calcification

Results from a new analysis show that patients with mitral annular calcification (MAC) who undergo minimally invasive mitral transcatheter edge-to-edge repair (M-TEER) experience similar reductions in mitral regurgitation (MR) and improvement in quality of life compared to those seen in patients without calcification.

24 Apr 2026

COVID-19 patients with STEMI show higher one-year mortality rates

Findings from the North American COVID-19 Myocardial Infarction (NACMI) registry demonstrate significantly higher one-year mortality rates in patients with COVID-19 and ST-elevation myocardial infarction (STEMI) compared to patients with STEMI alone.

24 Apr 2026

Real-world study examines cangrelor dosing for antiplatelet bridging after PCI

A multi-center retrospective cohort study examined how cangrelor has been used in real-world clinical practice around the time of surgery following percutaneous coronary intervention (PCI) and described differences in outcomes seen with different dosing approaches.

24 Apr 2026

Blood return system dramatically reduces blood loss during pulmonary thrombectomy

The first comparative analysis from the ENGULF (A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism) trial shows that using blood return during continuous aspiration thrombectomy dramatically reduces blood loss by 97%, while maintaining hemodynamic efficacy and improving procedural efficiency.

24 Apr 2026