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Study suggests new potentially druggable ways to target GPCR signaling

A study published in Nature by researchers at Duke University School of Medicine identifies a new way that G protein–coupled receptors (GPCRs) - targets of roughly one-third of FDA-approved drugs - control signaling in cells.

27 May 2026

True toll of long COVID may be double that of current estimates, research shows

The true toll of long COVID may be double that of current estimates and hidden from current surveillance systems that rely on capturing diagnostic codes, according to new research led by Mass General Brigham.

27 May 2026

Persistent gut microbiome changes linked to sustained colorectal cancer risk

More than a decade after removal of an adenoma-a precancerous mass-from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer (CRC), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

27 May 2026

Extreme trait values often have simpler genetic explanations than thought

Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.

27 May 2026

Degrading mutant KRAS protein induces greater lung cancer regression

KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.

27 May 2026

Prenatal therapy for cystic fibrosis improves lifelong health outcomes

This Cystic Fibrosis Awareness Month, Children's Hospital Colorado (Children's Colorado) is highlighting a growing shift in care: starting cystic fibrosis treatment before birth to improve lifelong health outcomes and reduce hospital stays.

27 May 2026

Study reveals how immune cells alter vascular plaque formation

A new LMU study shows how differently immune cells influence the formation of dangerous vascular deposits - and identifies miR-147 as a potential starting point for future therapies.

27 May 2026

Virtual reality navigation deficits predict future brain volume loss

Alzheimer's disease (AD) often begins long before it is clinically recognized, with subtle brain changes emerging years before noticeable memory loss or cognitive decline.

27 May 2026

Naturally occurring peptide can reverse drug resistance in melanoma

Melanoma is one of the deadliest forms of skin cancer, due in large part to its ability to rapidly develop resistance to treatment.

27 May 2026

Graphic cigarette ads may accidentally push smokers toward vaping

Graphic anti-smoking ads can lead smokers to reconsider their habit, but in the absence of similar warnings for e-cigarettes, they make some smokers more inclined to vape than quit.

27 May 2026

EEG reveals how coffee may secretly lower sleep quality

Evening coffee has sparked controversy for years. Some people fall asleep without difficulty, while others toss and turn for half the night.

27 May 2026

Poor lipid metabolism may reduce cognitive performance in teens

A new Finnish study shows that blood markers of dysfunctional lipid metabolism are associated with poorer cognitive function in 15-17-year-olds.

27 May 2026

Prenatal forever chemical exposure may affect puberty timing in children

An EHU-University of the Basque Country and Biogipuzkoa Health Research Institute study has linked certain chemicals measured during the first trimester of pregnancy to the subsequent onset of puberty in the children.

27 May 2026

Blocking sugar modification could boost breast cancer immunotherapy success

Immunotherapies such as so-called checkpoint inhibitors activate the body's own immune system to fight cancer cells and have revolutionized the treatment of many types of tumor.

27 May 2026

Lung cancer cells change identity to resist medical treatments

Cancer scientists have discovered that lung cancer cells can change their identity to resist treatment.

27 May 2026

European health sector workers face significant workplace carcinogen exposure

Exposure to cancer risk factors in the workplace remains an important and preventable cause of disease in Europe.

27 May 2026

Healthy hearts prior to pandemic reduced severe COVID-19 risk

Better heart health before the pandemic was linked to a lower risk of severe COVID-19 events, according to research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

27 May 2026

Women who sleep less may face more irregular menstrual cycles

A study on 42,759 menstrual cycles shows that sleep quality affects menstrual health, with implications for physiological stability and individual variability.

27 May 2026

Efficient pitching mechanics can help avoid career-threatening elbow injuries

As professional baseball sees another high-profile elbow injury with Toronto Blue Jays right-hander José Berríos having undergone ulnar collateral ligament (UCL) surgery, new research from the University of Waterloo suggests many pitchers may be able to reduce stress on their elbows without sacrificing velocity.

27 May 2026

Why blood pressure rises faster in women after midlife

This review examines how sex-specific blood pressure trajectories are shaped by genetics, hormones, metabolic risk factors, lifestyle exposures, environmental stressors, and medical treatments. It highlights that women generally have lower blood pressure earlier in life but may experience steeper increases with aging, especially around and after menopause, with exogenous stressors appearing to have a greater impact in women than in men.

27 May 2026