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Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

18 Nov 2025

Blocking mir-21 shows promise for slowing bladder cancer growth

Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal surgery, and despite advances in systemic therapies, recurrence is frequent in the most aggressive forms of the disease.

18 Nov 2025

Study finds low uptake of colorectal cancer testing among adults aged 45 to 49

UCLA research finds that fewer than 1 in 4 eligible younger adults completed colorectal cancer screenings after the United States Preventive Services Task Force (USPSTF) lowered the recommended screening age to 45 from 50.

18 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Trial investigates how quickly human milk responds to common plant based meat swaps

Replacing beef with a plant based beef substitute for six days changed the fatty acid composition of human milk, increasing medium chain saturated fats and lowering key long chain polyunsaturated fats such as arachidonic acid. These biochemical shifts occurred without changes in maternal weight, appetite, glucose patterns or infant milk intake.

18 Nov 2025

Study links obesity severity to escalating cardiometabolic and renal disease burden

Obesity severity is incrementally associated with a broad range of cardiometabolic and renal disease burden, as discovered by researchers at Pennington Biomedical Research Center. Recently published in Obesity, the paper "Association of Obesity Severity with Cardiometabolic and Renal Disease Burden in the United States," explored the relationship through a cross-sectional study of data from the U.S. Behavioral Risk Factor Surveillance System survey.

18 Nov 2025

Machine learning tool helps evaluate ICU resource efficiency in severe pneumonia care

A study published in the Journal of Critical Care, conducted with the participation of the D'Or Institute for Research and Education (IDOR), investigated how to measure efficiency in the use of resources for patients with severe community-acquired pneumonia (CAP), an illness contracted outside hospital settings and most common among older adults.

18 Nov 2025

Tirzepatide reveals a brain signal that predicts returning food preoccupation

Researchers implanted electrodes in the human nucleus accumbens to track brain activity during severe food preoccupation in an individual taking tirzepatide. They found that a delta–theta biomarker disappeared during symptom-free periods and re-emerged weeks before relapse, suggesting a possible neural marker of vulnerability to dysregulated eating.

18 Nov 2025

Alzheimer’s drugs improve key cognitive skills in children with autism and low IQ

The review synthesizes evidence on whether Alzheimer’s disease medications can improve neurocognitive outcomes in children and adolescents with autism and low IQ. Across 12 studies, preliminary findings show promising gains in language, executive function, learning and memory, and general cognitive ability, particularly in younger children.

18 Nov 2025

Analysis finds even low-intensity smokers have higher risk of heart disease and death

An analysis of data from almost two dozen long-term studies finds that even low-intensity smokers have a substantially higher risk of heart disease and death compared to people who never smoked, even years after they quit.

18 Nov 2025

Scientists investigate the role of the extracellular matrix in tissue growth

Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process.

18 Nov 2025

Novel therapy reduces tumor growth in models of triple-negative breast cancer

Researchers at the University of California San Diego School of Medicine have identified a promising new therapy for triple-negative breast cancer (TNBC), which is among the most aggressive and difficult-to-treat forms of the disease.

18 Nov 2025

Encapsulated hormone therapy strengthens osteoporotic bones while avoiding side effects

Postmenopausal osteoporosis is a condition that weakens bones, making them brittle and prone to fracture.

18 Nov 2025

New transplant approach resets the immune system to stop Type 1 diabetes

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

18 Nov 2025

New model uses social media patterns to predict disease outbreaks

Vaccination rates are falling in many communities due to widespread misinformation and previously eliminated or controlled illnesses like measles are surging across the United States and Canada.

18 Nov 2025

Scientists urge careful evaluation before applying AI virtual staining in healthcare workflows

Artificial intelligence has exploded in popularity in recent years, and many proponents are excited about its potential uses in medicine: for example, processing samples quickly or identifying markers of disease that may be missed by the human eye.

18 Nov 2025

Deformability helps cancer cells squeeze through tight tissue gaps, study shows

Aggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival.

18 Nov 2025

Year-long adherence to buprenorphine sharply reduces overdose risk in young people

New research from Mass General Brigham finds that adolescents and young adults who stayed on the medication buprenorphine for at least a year had markedly lower risks of opioid overdose and hospitalization compared with peers who discontinued medication early or took it inconsistently.

18 Nov 2025

Study reveals how gestational diabetes disrupts the placenta at the molecular level

Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

18 Nov 2025

Acute and chronic depression involve different mechanisms in the brain

A new study investigating neuroinflammation in the ventral tegmental area (VTA) of the brain, a small, midbrain dopaminergic region, has found that acute and chronic depression are associated with distinct pathophysiological mechanisms.

18 Nov 2025

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Medical Research News

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Blocking mir-21 shows promise for slowing bladder cancer growth

Study finds low uptake of colorectal cancer testing among adults aged 45 to 49

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Trial investigates how quickly human milk responds to common plant based meat swaps

Study links obesity severity to escalating cardiometabolic and renal disease burden

Machine learning tool helps evaluate ICU resource efficiency in severe pneumonia care

Tirzepatide reveals a brain signal that predicts returning food preoccupation

Alzheimer’s drugs improve key cognitive skills in children with autism and low IQ

Analysis finds even low-intensity smokers have higher risk of heart disease and death

Scientists investigate the role of the extracellular matrix in tissue growth

Novel therapy reduces tumor growth in models of triple-negative breast cancer

Encapsulated hormone therapy strengthens osteoporotic bones while avoiding side effects

New transplant approach resets the immune system to stop Type 1 diabetes

New model uses social media patterns to predict disease outbreaks

Scientists urge careful evaluation before applying AI virtual staining in healthcare workflows

Deformability helps cancer cells squeeze through tight tissue gaps, study shows

Year-long adherence to buprenorphine sharply reduces overdose risk in young people

Study reveals how gestational diabetes disrupts the placenta at the molecular level

Acute and chronic depression involve different mechanisms in the brain

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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