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Researchers provide a global catalog of human pluripotent stem cell lines for clinical use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

18 Dec 2025

New tear gland organoids shed light on the biology of dry eye disease

An estimated 5-15% of people have problems with dry eyes, with symptoms including eye redness, stinging, or burning sensation, and eye fatigue. Dry eye disease (DED) occurs when the eyes' tear glands produce insufficient or poor-quality tears which can be due to allergy or autoimmune disease, hormonal changes, aging, etc.

18 Dec 2025

How diabetes medications may influence cancer risk and progression

Diabetes, particularly Type 2 Diabetes (T2DM), has been linked to an increased risk of various cancers, including liver, colorectal, and breast cancer.

18 Dec 2025

Early peanut introduction can prevent allergy but parents need clearer guidance

Feeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new study published in JAMA Network Open found that parents need more support to get it right.

18 Dec 2025

Phages use small RNA to hijack bacterial cells and boost replication

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

18 Dec 2025

Ants show new promise as a source of powerful antibiotics

Has a crucial component to the development of human medicine been hiding under our feet?

18 Dec 2025

HPV vaccination reduces risk of vulvar and vaginal lesions

Girls who are vaccinated against HPV are not only well protected against cervical cancer; they are also less likely to develop severe precancerous lesions of the vulva and vagina, particularly if they were vaccinated before the age of 17.

18 Dec 2025

Financial strain and food insecurity drive accelerated cardiac aging

A novel analysis investigating the contribution of social determinants of health (SDoH) to cardiac aging has found that financial strain and food insecurity are the strongest drivers of accelerated biological aging and increased mortality risk.

18 Dec 2025

Estrogen drives gut pain and explains higher rates of IBS in women

Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort.

18 Dec 2025

Ultra-processed foods linked to higher mortality in Black women with breast cancer

A study from Rutgers Cancer Institute researchers in eClinicalMedicine is the first to link ultra-processed foods to reduced survival in Black women with breast cancer.

18 Dec 2025

Hybrid care improves access to primary care in rural Ontario

Hybrid health options are an underdeveloped, key tool for improving access to primary care in Ontario's remote communities, with a new University of Ottawa study highlighting the positive impact of in-person mixed with virtual care options have in rural regions.

18 Dec 2025

Lung immune cells switch roles to drive allergic inflammation

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune responses.

18 Dec 2025

New breakthrough expands possibilities for PET imaging

Imagine being able to watch organs and tissues work in real time. That's the power of Positron Emission Tomography, or PET imaging, a technology that gives physicians and researchers a window into cellular processes.

18 Dec 2025

Researchers point to mitochondria as a missing link between mental health and brain function

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

18 Dec 2025

Orthorexia nervosa links strongly to perfectionism and OCD traits, review shows

This umbrella review synthesised five meta-analyses to estimate the reported prevalence of orthorexia nervosa and examine its psychological correlates. Findings show wide variability in prevalence estimates and consistent links with eating disorder symptoms, obsessive-compulsive traits, and perfectionistic strivings, limited by high methodological heterogeneity.

18 Dec 2025

Study finds Brain Care Score as a strong predictor of stroke across racial groups

A new study from Mass General Brigham found the Brain Care Score (BCS) is a strong predictor of stroke across different racial groups in the U.S.

18 Dec 2025

Fertility preferences remain high in rural Tanzania despite family planning access

Fertility rates in much of Sub-Saharan Africa remain high, despite declining child mortality and improved access to contraceptives and female education - factors that generally lead to smaller families and improved economic conditions in developing countries.

18 Dec 2025

New nanoparticle vaccines show promise against multiple deadly filoviruses

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.

18 Dec 2025

Everyday light exposure shapes how alert and mentally sharp we feel outside the lab

This real-world study shows that recent and habitual light exposure are linked to lower subjective sleepiness and faster reaction times in daily life. Brighter and more stable daytime light patterns were associated with better performance on specific cognitive tasks, independent of sleep and time of day.

18 Dec 2025