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Genomic profiling uncovers distinct TP53 and PI3K pathways across tumor budding grades

A newly proposed International Association for the Study of Lung Cancer (IASLC) tumor budding-based grading system successfully identified patients with resected lung squamous cell carcinoma (SqCC) at higher risk of poor outcomes and showed potential to help guide selection for adjuvant chemotherapy, according to research presented at the IASLC 2026 World Conference on Lung Cancer on Lung Cancer. (WCLC).

15 Sep 2026

Stage 1 findings support continued pivotal phase evaluation of gotistobart

Patients with metastatic squamous non-small cell lung cancer (NSCLC) whose disease progressed following PD-(L)1 inhibitor therapy experienced a median overall survival of 18.5 months with the investigational anti-CTLA-4 antibody gotistobart compared with 10.0 months for patients receiving docetaxel, according to updated findings from Stage 1 of the Phase 3 PRESERVE-003 trial.

15 Sep 2026

Mobile LDCT lung cancer screening can reach vulnerable populations in resource-limited settings

Mobile low-dose computed tomography (LDCT) screening can reach high-risk and socially vulnerable populations in resource-limited settings, according to initial results from the Third Brazilian Early Lung Cancer Trial (BRELT3) presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC).

15 Sep 2026

Research identifies novel prognostic biomarkers for class II and III BRAF-altered cancers

Patients with metastatic non-small cell lung cancer (NSCLC) harboring class II and class III BRAF alterations have distinct clinicopathologic and genomic characteristics, with class III alterations potentially associated with worse prognosis, according to research presented today at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC).

15 Sep 2026

Study links processed foods to targeted domain-specific cognitive decline

An unhealthy Western-style diet was associated with a faster cognitive decline in people with a genetic risk of Alzheimer's disease, according to new research led by Murdoch University and Alzheimer's Research Australia.

15 Sep 2026

Early consolidative SRT shows value in EGFR-mutant NSCLC with limited brain metastases

Early cranial stereotactic radiotherapy (SRT) administered with first-line osimertinib was associated with improved intracranial control and survival outcomes in patients with EGFR-mutant non-small cell lung cancer (NSCLC) and limited brain metastases, according to research presented at the International Association for the Study of Lung Cancer (IASLC) 2026 World Conference on Lung Cancer (WCLC).

15 Sep 2026

Orexo announces FDA acceptance of Investigational New Drug (IND) application for OX640 for the treatment of anaphylaxis

Orexo AB (publ.) today announces that the U.S. Food and Drug Administration (FDA) has accepted its Investigational New Drug (IND) application for OX640, a nasally administered powder formulation of epinephrine intended for the emergency treatment of anaphylaxis.

15 Sep 2026

Adolescent cannabis use disorder diagnoses rise after legalization

New diagnoses of cannabis use disorder (CUD) among adolescents in Northern California began climbing after recreational cannabis was legalized in California in 2016, reversing a steady decline in the three years prior, according to a new study published in the journal Addiction.

15 Sep 2026

Brain MRI surveillance without prophylactic cranial irradiation reduces cognitive failure risk in patients with SCLC

In the SWOG S1827 MAVERICK phase III randomized trial, patients with small-cell lung cancer (SCLC) who underwent regular brain MRI surveillance without prophylactic cranial irradiation (PCI) had significantly better cognitive failure–free survival (the primary endpoint of the trial), without an apparent difference in overall survival, according to results presented at the Presidential Symposium of the IASLC 2026 World Conference on Lung Cancer, hosted by the International Association for the Study of Lung Cancer, in Seoul, Republic of Korea.

15 Sep 2026

A study of more than 21,000 adults found an unusual link between psilocybin and diet

Using data from more than 21,800 adults in two UK birth cohorts, researchers found that lifetime psilocybin and LSD use was associated with stronger pro-environmental attitudes and a greater likelihood of following a vegetarian diet, with psilocybin showing the clearer dietary pattern. Mediation analyses suggested that environmental attitudes statistically accounted for the psilocybin-vegetarianism association and part of the association with lower red meat consumption, but the observational design cannot establish causation.

15 Sep 2026

Air pollution linked to higher risks of glaucoma and cataract

People who live in areas with higher levels of air pollution are more likely to develop glaucoma and cataract, according to a large study presented today (Monday) at the 44th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).

15 Sep 2026

Your voice could add something aging blood tests and scans miss

Researchers found that a standardized 30-second voice recording could predict chronological age with mean absolute errors of 3.95 years in females and 4.41 years in males. The resulting Voice Age measure also captured physiological information partly distinct from molecular, imaging, sleep, and lifestyle-based aging clocks, supporting its potential as a functional aging biomarker.

15 Sep 2026

Ultra-processed foods enter babies’ diets early. What comes with them?

In a Denver cohort of 114 healthy infants, higher ultra-processed food intake during complementary feeding was associated with greater added sugar and sodium intake at 9 and 12 months. UPF intake showed no consistent relationship with growth through 12 months, while dietary diversity was not reduced among infants consuming more UPFs.

14 Sep 2026

MRI surveillance alone improves outcomes for patients with small-cell lung cancer

Results from the international phase III SWOG S1827 MAVERICK trial show that brain MRI surveillance alone improved cognitive failure-free survival compared with MRI surveillance plus prophylactic cranial irradiation (PCI) in patients with small-cell lung cancer (SCLC).

14 Sep 2026

Simple eye test identifies patients suitable for laser blended vision

Laser blended vision is a treatment for presbyopia, the natural deterioration of our ability to see things close up, that develops in people aged 40 and over.

14 Sep 2026

European registry shows continued improvements in cataract surgery outcomes

A total of 363,039 cataract surgeries performed in 12 European countries in 2024 have been recorded in the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO), according to the latest figures presented at the 44th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) today (Tuesday).

14 Sep 2026

Eye scans detect signs of atrial fibrillation years before diagnosis

People with atrial fibrillation have signs of the condition in the retinas of their eyes that can be detected as early as four years before diagnosis, finds a new study led by University College London (UCL) and Moorfields researchers.

14 Sep 2026

Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected

In a US multicenter electronic health record study, researchers compared tirzepatide with semaglutide in adults with asthma and type 2 diabetes, matching 8,176 patients in each treatment group. Asthma exacerbation risk was similar between treatments, while tirzepatide was associated with a lower likelihood of receiving a short-acting beta-agonist prescription.

14 Sep 2026

An 8-hour eating window stood out for weight loss, but the full picture is more complicated

A pooled analysis of individual data from five time-restricted eating trials involving 124 adults linked shorter eating windows with modestly greater weight loss. Eight-hour TRE was associated with greater weight loss than 12-hour TRE and controls, while cardiometabolic outcomes showed no consistent relationship with eating-window duration and several weight associations weakened after adjustment.

14 Sep 2026

More hospitals are adopting AI, yet the access gap is proving hard to close

A national analysis of 6,166 US hospitals found that specific workflow AI capabilities were associated with higher sepsis bundle completion rates and lower 30-day pneumonia mortality, whereas robotics showed narrower procedural associations. Geographic access remained highly uneven, with about 114.6 million people in the access-analysis population living more than 30 minutes from an AI-enabled hospital, although the observational design prevents causal conclusions.

14 Sep 2026

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Medical Research News

Genomic profiling uncovers distinct TP53 and PI3K pathways across tumor budding grades

Stage 1 findings support continued pivotal phase evaluation of gotistobart

Mobile LDCT lung cancer screening can reach vulnerable populations in resource-limited settings

Research identifies novel prognostic biomarkers for class II and III BRAF-altered cancers

Study links processed foods to targeted domain-specific cognitive decline

Early consolidative SRT shows value in EGFR-mutant NSCLC with limited brain metastases

Orexo announces FDA acceptance of Investigational New Drug (IND) application for OX640 for the treatment of anaphylaxis

Adolescent cannabis use disorder diagnoses rise after legalization

Brain MRI surveillance without prophylactic cranial irradiation reduces cognitive failure risk in patients with SCLC

A study of more than 21,000 adults found an unusual link between psilocybin and diet

Air pollution linked to higher risks of glaucoma and cataract

Your voice could add something aging blood tests and scans miss

Ultra-processed foods enter babies’ diets early. What comes with them?

MRI surveillance alone improves outcomes for patients with small-cell lung cancer

Simple eye test identifies patients suitable for laser blended vision

European registry shows continued improvements in cataract surgery outcomes

Eye scans detect signs of atrial fibrillation years before diagnosis

Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected

An 8-hour eating window stood out for weight loss, but the full picture is more complicated

More hospitals are adopting AI, yet the access gap is proving hard to close

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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