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New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

In a new preclinical study, researchers from The University of Texas MD Anderson Cancer Center developed an antibody therapy called 77A that showed an ability to overcome treatment resistance in blood cancers, such as myeloma and lymphoma, as well as solid tumors.

9 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

New study reveals productivity losses from substance use disorder in the U.S.

A new study shows that in 2023, substance use disorders led to nearly $93 billion in lost productivity in the United States from missed work, reduced job performance, inability to work, and lost household productivity.

9 Dec 2025

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

Researchers at Bielefeld University have analyzed how reliably AI methods can detect pulse rates from simple video recordings.

9 Dec 2025

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study from the University of Gothenburg.

9 Dec 2025

Physical activity may help restore ease of movement and agility during aging

The brain-chemical surge that comes with running may bolster coordination and speed in the old and young alike, a new study of middle-aged mice shows.

9 Dec 2025

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

Routine blood test may flag hidden osteoporosis risk, study finds

A large hospital-based cross-sectional study examined whether routinely measured serum alkaline phosphatase can indicate osteoporosis risk in adults undergoing health checks. Higher ALP levels, even within the normal range, were associated with greater osteoporosis likelihood, particularly in younger, female, and metabolically healthy individuals.

9 Dec 2025

Supportive marriages may shape appetite control through oxytocin and the brain–gut axis

Supportive marital relationships are associated with lower BMI, fewer food addiction symptoms, higher oxytocin, stronger frontal brain responses to food cues, and favorable gut tryptophan metabolites. These coordinated social, neural, hormonal, and gut pathways suggest a plausible biological link between emotional support and healthier eating regulation.

8 Dec 2025

Hotter days and nights are already stealing sleep across the U.S.

Rising nighttime and daytime temperatures are associated with reduced sleep duration, poorer sleep continuity, delayed sleep onset, and altered sleep stages in a large U.S. cohort tracked with wearable devices. Vulnerability is greatest among adults aged 40–50 years, females, people with lower socioeconomic status, chronic conditions, and those living in marine climate zones, with climate change projected to further magnify sleep loss.

8 Dec 2025

Everyday PFAS exposure alters placental function in early pregnancy

This study measured real-life PFAS concentrations in first-trimester human placentas and used these data to create a pregnancy-relevant PFAS mixture. In 3D trophoblast spheroid models, the mixture altered invasion, hormone secretion, and gene expression without broadly reducing viability at environmentally relevant doses.

8 Dec 2025

A 36-week screening strategy safely reduces pre-eclampsia at term

Screening pregnant women at 36 weeks using a validated risk model and offering risk-stratified planned early-term birth reduced the incidence of term pre-eclampsia by about 30 percent without increasing maternal or neonatal complications. The randomised PREVENT-PE trial demonstrates that a personalised timing-of-birth strategy can prevent term pre-eclampsia where no effective medical prevention currently exists.

8 Dec 2025

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Early-life RSV infection and parental allergy interact to substantially increase childhood asthma risk, supported by population data from more than 1.5 million children and mechanistic mouse experiments. The study shows that viral infection reprograms neonatal immune responses by altering how maternally transferred allergen-specific antibodies are handled, driving long-term allergic airway disease.

8 Dec 2025

Laughing gas shows fast antidepressant effects in early clinical trials

A systematic review and meta-analysis in eBioMedicine shows that nitrous oxide can rapidly reduce depressive symptoms within hours, particularly at higher doses, but effects are short-lived after single treatments. Repeated dosing appears to extend and strengthen antidepressant benefits, although the current evidence is based on small, early-phase trials with limited long-term safety data.

8 Dec 2025

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

SARS‑CoV‑2, the virus that causes COVID-19, continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid.

8 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

Industrial and farm chemicals quietly alter the balance of gut microbes

This study systematically screened over 1,000 agricultural and industrial chemicals and found that many can inhibit human gut bacteria in vitro. Beyond antimicrobial effects, these chemicals act as selective pressures that can reshape microbial competition, tolerance mechanisms, and metabolic pathways.

8 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Most patients with a rare and aggressive form of large B-cell lymphoma can safely receive a less toxic treatment than the intensive chemotherapy often used, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

8 Dec 2025

Why female athletes need injury prevention rules built for women, not men

This International Olympic Committee consensus synthesised evidence from over 600 studies to develop 56 injury prevention recommendations tailored to female, woman and girl athletes. It concludes that reducing injury risk requires a whole sports system approach that integrates training, policy, environment and culture, not exercise alone.

8 Dec 2025

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Medical Research News

New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

Australian researchers pinpoint specific genetic changes linked to severe AMD

New study reveals productivity losses from substance use disorder in the U.S.

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

Physical activity may help restore ease of movement and agility during aging

Study reveals how brain protein KCC2 influences reward learning

Routine blood test may flag hidden osteoporosis risk, study finds

Supportive marriages may shape appetite control through oxytocin and the brain–gut axis

Hotter days and nights are already stealing sleep across the U.S.

Everyday PFAS exposure alters placental function in early pregnancy

A 36-week screening strategy safely reduces pre-eclampsia at term

Early RSV infection turns maternal allergy into a powerful driver of childhood asthma

Laughing gas shows fast antidepressant effects in early clinical trials

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

Industrial and farm chemicals quietly alter the balance of gut microbes

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Why female athletes need injury prevention rules built for women, not men

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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