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Global debate continues over fair allocation of donor hearts

As demand for heart transplants continues to far exceed the number of available donor hearts, experts at today's 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) explored a critical question: how should this scarce, life-saving resource be allocated?

25 Apr 2026

Space research accelerates heart disease studies and tissue engineering

By studying and engineering heart tissue in the unique low-gravity environment of space, the laboratory of Arun Sharma, PhD, is uncovering new ways to protect and repair the failing heart.

25 Apr 2026

Natural compound obakulactone shows therapeutic potential for rheumatoid arthritis

A new study published in Engineering reveals that obakulactone (OL), a natural tetracyclic triterpenoid isolated from Phellodendri cortex, exerts a therapeutic effect on rheumatoid arthritis (RA) by promoting the degradation of acyl coenzyme A thioesterase 1 (ACOT1) via the ubiquitin‒proteasome pathway and restoring the homeostasis of unsaturated fatty acids.

25 Apr 2026

Researchers pioneer breakthrough therapy for life-threatening infections

A revelatory treatment for patients with life-threatening infectious diseases is being pioneered in Melbourne by researchers at The Alfred and Monash University.

25 Apr 2026

Glycocalyx modification boosts immune cell targeting against B lymphoma

A new study published in Engineering provides mechanistic insights into live-cell glycocalyx engineering and supports the rational design of next-generation adoptive cell therapies (ACTs) against B lymphoma, addressing limitations such as high costs and restricted antigen specificity in current treatments.

25 Apr 2026

Fucosylated IgG drives adipose tissue dysfunction during aging

A study published in Engineering has identified fucosylated immunoglobulin G (IgG) as a key mediator contributing to adipose tissue dysfunction during aging, offering insights into age-related metabolic disorders and potential therapeutic targets.

25 Apr 2026

Shared brain connectivity patterns found across major neurodevelopmental disorders

Differences in brain connectivity are linked to several neurodevelopmental disorders, yet scientists still struggle to determine what changes are shared or unique to each condition.

25 Apr 2026

Traditional plant extract may treat bone and mood disorders in postmenopausal women

Postmenopausal women are at higher risk for both osteoporosis and depression, yet no single treatment effectively addresses both conditions because their shared biological basis remains poorly understood.

25 Apr 2026

Bacterial vesicles emerge as powerful tools against antibiotic resistance

Antibiotic resistance is making bacterial infections harder to treat, demanding new therapeutic strategies. A new review highlights bacterial extracellular vesicles (BEVs) as promising nanoscale tools that can kill pathogens, block infection, enhance vaccines, and deliver drugs.

25 Apr 2026

Study finds different types of crystalloid fluids are equally effective for pediatric sepsis

A major study, led by researchers at Children's Hospital of Philadelphia, Nemours Children's Health, and Children's National Hospital and involving an extensive network of medical centers across the United States and abroad, found that different types of crystalloid fluid resuscitation were equally effective for staving off the most serious adverse kidney events after the treatment of pediatric patients with suspected septic shock.

25 Apr 2026

U.S. child mortality rates remain higher than other high-income nations

At every age, children in the United States die at higher rates than peers in other high-income nations, according to a new study from Children's Hospital of Philadelphia.

25 Apr 2026

Ultra-processed foods linked to measurable drops in human attention span

New research from Monash University, the University of São Paulo and Deakin University shows a diet high in heavily processed foods can negatively impact the brain's ability to focus and increases the risk of developing dementia.

25 Apr 2026

The heart's constant beating suppresses tumor growth in cardiac tissues

The heart's constant beating may actively suppress tumor growth in cardiac tissues, a new study reports. This is because cellular pathways in these tissues alter gene regulation in cancer cells to keep them from proliferating.

25 Apr 2026

Molecular map reveals how Down syndrome alters brain development

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth - a resource that resolves longstanding contradictions in the field and could lay the groundwork for future therapeutic strategies.

25 Apr 2026

Losing weight improves heart muscle contraction in people with obesity and heart failure

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Medical Research News

Global debate continues over fair allocation of donor hearts

Space research accelerates heart disease studies and tissue engineering

Natural compound obakulactone shows therapeutic potential for rheumatoid arthritis

Researchers pioneer breakthrough therapy for life-threatening infections

Glycocalyx modification boosts immune cell targeting against B lymphoma

Fucosylated IgG drives adipose tissue dysfunction during aging

Shared brain connectivity patterns found across major neurodevelopmental disorders

Traditional plant extract may treat bone and mood disorders in postmenopausal women

Bacterial vesicles emerge as powerful tools against antibiotic resistance

Study finds different types of crystalloid fluids are equally effective for pediatric sepsis

U.S. child mortality rates remain higher than other high-income nations

Ultra-processed foods linked to measurable drops in human attention span

The heart's constant beating suppresses tumor growth in cardiac tissues

Molecular map reveals how Down syndrome alters brain development

Losing weight improves heart muscle contraction in people with obesity and heart failure

Intercellular heme transfer pathway sustains red blood cell production under stress

Fibroblast subtype found to be essential for coordinating immune cells within lymph nodes

Eccentric exercise builds muscle strength and size with less effort

New insight into how molecular measures of aging relate to neuroimaging markers of brain health

Improving health literacy reduces health inequalities among university students in Japan

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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