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Understanding how the immune system protects against fungal pathogenicity

The yeast Candida albicans colonizes mucosal surfaces and is usually harmless. However, under certain conditions it can cause dangerous infections.

15 Dec 2025

How brain cells manage long distance genetic instructions

Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated groups.

15 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

Two compounds sourced from cannabis show promising anti-cancer effects

In the future, scientists could use drugs made from cannabis to fight ovarian cancer. A team of scientists testing the effects of two chemical compounds sourced from cannabis on ovarian cancer cells have found that both show promising anti-cancer effects.

15 Dec 2025

Gut bacteria mimicry can accelerate the progression of multiple sclerosis

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system.

15 Dec 2025

Global study finds stark differences in survival among children with cancer

Every year, more than 200,000 children under the age of 15 are diagnosed with cancer worldwide, and nearly 75,000 die from the disease.

15 Dec 2025

Study identifies a distinctive, measurable pattern of brain activity in children with ADHD

A new study suggests that children with ADHD may exhibit a distinctive, measurable pattern of brain activity that could reflect differences in neural efficiency.

15 Dec 2025

Study: 1 in 4 children with major trauma do not receive care in pediatric trauma centers

New research shows that 1 in 4 children with major traumatic injury do not receive care in a pediatric trauma centre, where outcomes are generally better than in adult centers.

15 Dec 2025

A new trial investigates whether the MIND diet can be scaled for obesity management

This study protocol outlines a 12-week randomized trial testing whether a MIND diet intervention is feasible, acceptable, and sustainable for adults with obesity in Sweden. It will generate preliminary evidence on adherence, mental well-being, and gut microbiota changes to inform larger efficacy trials.

14 Dec 2025

E-cigarette use is linked to higher heart attack risk, especially in former smokers

his systematic review and meta-analysis examined whether electronic cigarette use is associated with myocardial infarction and stroke, synthesizing evidence from 12 observational studies. The analysis found higher odds of myocardial infarction among e-cigarette users, particularly former smokers, while no significant associations were observed among exclusive never-smokers.

14 Dec 2025

Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations

A large NHANES analysis found that nearly four in ten US adults met criteria for metabolic syndrome between 2013 and 2023, with no statistically significant change in overall prevalence. However, prevalence rose significantly among adults aged 60 years and older and among non-Hispanic Black individuals, alongside a significant non-linear increase in hypertriglyceridemia.

14 Dec 2025

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.

14 Dec 2025

Researchers develop powerful tools for microbiome research advancement

The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the planet's ecosystems. Yet even with modern DNA sequencing, figuring out what these microbes are and how they are related to one another remains extremely difficult.

13 Dec 2025

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025

Engineering muscle stem cells for sustainable cultured meat production

The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible tissues. Muscle stem cells, or satellite cells, are central to this process due to their ability to regenerate and form muscle fibers.

13 Dec 2025

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

13 Dec 2025

Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis

Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.

13 Dec 2025

Lowering blood sugar reduces heart risk in prediabetes

Lowering blood sugar levels halves the likelihood of serious heart problems in people with prediabetes.

12 Dec 2025

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

A new study from the University of Oklahoma suggests that small genetic differences in two proteins – previously known for their role in premature infants' lungs – may also influence how their eyes develop, potentially affecting the risk of retinopathy of prematurity (ROP).

12 Dec 2025

Virus shells use asymmetry to control RNA release and infection

Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research led by scientists at Penn State reveals a deliberate imbalance in their shape that helps them infect their hosts.

12 Dec 2025

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Medical Research News

Understanding how the immune system protects against fungal pathogenicity

How brain cells manage long distance genetic instructions

Single-pill combination medications may simplify treatment for adults with high blood pressure

Two compounds sourced from cannabis show promising anti-cancer effects

Gut bacteria mimicry can accelerate the progression of multiple sclerosis

Global study finds stark differences in survival among children with cancer

Study identifies a distinctive, measurable pattern of brain activity in children with ADHD

Study: 1 in 4 children with major trauma do not receive care in pediatric trauma centers

A new trial investigates whether the MIND diet can be scaled for obesity management

E-cigarette use is linked to higher heart attack risk, especially in former smokers

Metabolic syndrome affects nearly four in ten US adults as rates climb in older and Black populations

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Researchers develop powerful tools for microbiome research advancement

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Engineering muscle stem cells for sustainable cultured meat production

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

Single-cell RNA-seq reveals FBLN7's role in adipose tissue fibrosis

Lowering blood sugar reduces heart risk in prediabetes

Genetic differences in surfactant proteins influence retinopathy of prematurity risk

Virus shells use asymmetry to control RNA release and infection

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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