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New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders

This editorial argues that GLP-1 receptor agonists could substantially improve healthspan and reduce premature mortality in people with serious mental illnesses by targeting cardiometabolic risk rather than psychiatric symptoms alone. It highlights emerging evidence, safety considerations, and equity challenges that position GLP-1 RAs as a promising public health strategy for this high-risk population.

25 Jan 2026

Evidence links gut microbiome changes to Alzheimer’s progression

Human studies consistently report gut microbiome differences in mild cognitive impairment and Alzheimer’s disease, but findings vary widely by cohort, methods, and taxa. Heterogeneity and limited longitudinal data prevent causal inference, highlighting the need for functional profiling and well-designed intervention trials.

25 Jan 2026

Why the age you start smoking matters as much as how much you smoke

Starting smoking at a younger age is associated with substantially higher risks of myocardial infarction, stroke, and death, even after accounting for cumulative smoking exposure. Early initiation also amplifies the cardiovascular harm of heavier smoking, indicating increased vulnerability when smoking begins in adolescence.

25 Jan 2026

The long and short of it: Human penis size evolved for both attraction and rivalry, study suggests

This experimental study used life-sized and screen-based 3D male avatars to test how penis size, height, and body shape influence female mate choice and male assessments of rivals. The findings show non-linear female preferences for size and demonstrate that penis size functions as a modest but significant cue in male perceptions of fighting ability, alongside stronger traits such as height and torso shape.

25 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Microbiome differences distinguish preterm infants with parenteral nutrition-associated cholestasis

24 Jan 2026

Colorblindness linked to delayed bladder cancer detection and higher mortality

Recognizing the sight of blood in urine, the most common first sign of bladder cancer, is often the impetus that leads people to a diagnosis.

24 Jan 2026

Firefighter protective gear restricts movement and may increase injury risk

When firefighters respond to an emergency, the gear they wear to protect themselves can also create challenges that could jeopardize their performance and safety.

24 Jan 2026

Selective inhibition of cPLA2 shows promise against Alzheimer's-related brain inflammation

A multidisciplinary USC research team has identified new compounds that may target a key driver of brain inflammation linked to Alzheimer's disease. Their research just published in the Nature publication npj Drug Discovery.

24 Jan 2026

Large multi-ancestry study expands understanding of schizophrenia genetics

A landmark study led by researchers with the Department of Veterans Affairs has uncovered new genetic insights into schizophrenia by analyzing data from ancestrally diverse populations, including African Americans, through the Million Veteran Program (MVP) and Cooperative Studies Program (CSP).

24 Jan 2026

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD).

24 Jan 2026

Experimental study reveals advanced episodic memory replay in rats

In a new study Indiana University researchers observed episodic memory in rats to a degree never documented before, suggesting that rats can serve as a model for complex cognitive processes often considered exclusively human.

24 Jan 2026

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

24 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Shared genetic architecture links schizophrenia with hemispheric white matter microstructure

Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in adolescence or early adulthood and characterized by hallucinations, delusions, disorganized thinking, and cognitive impairments; while its etiology remains elusive, genetic factors are widely recognized as fundamental, and GWAS have identified over 200 genome-wide significant loci.

24 Jan 2026

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Prediabetes is an extremely heterogeneous metabolic disorder. Scientists from several partner institutes of the German Center for Diabetes Research (DZD) have now used artificial intelligence (AI) to identify epigenetic markers that indicate an elevated risk of complications.

24 Jan 2026

Short-term oatmeal diet improves cholesterol and metabolic health markers

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Medical Research News

New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders

Evidence links gut microbiome changes to Alzheimer’s progression

Why the age you start smoking matters as much as how much you smoke

The long and short of it: Human penis size evolved for both attraction and rivalry, study suggests

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Microbiome differences distinguish preterm infants with parenteral nutrition-associated cholestasis

Colorblindness linked to delayed bladder cancer detection and higher mortality

Firefighter protective gear restricts movement and may increase injury risk

Selective inhibition of cPLA2 shows promise against Alzheimer's-related brain inflammation

Large multi-ancestry study expands understanding of schizophrenia genetics

PTPN2 gene protects the gut from harmful bacteria driving inflammatory bowel disease

Experimental study reveals advanced episodic memory replay in rats

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Shared genetic architecture links schizophrenia with hemispheric white matter microstructure

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Short-term oatmeal diet improves cholesterol and metabolic health markers

Evidence of African lineage Zika virus circulation in neotropical primates in Southern Brazil

MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors

Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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