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Newly discovered survival pathway explains stubborn EGFR-driven lung cancers

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells become highly resistant to treatment after developing mutations in a key gene called EGFR (epidermal growth factor receptor).

21 Jan 2026

Shingles vaccination is linked to slower biological aging in older adults

This population-based study of U.S. adults aged 70 and older found that shingles vaccination was associated with slower epigenetic and transcriptomic aging, as well as lower systemic inflammation. No significant associations were observed for neurodegeneration or cardiovascular biomarkers, highlighting domain-specific molecular effects rather than broad clinical changes.

21 Jan 2026

Study finds no safety or efficacy gap between paracetamol and ibuprofen for neonatal PDA

In a UK pilot randomized trial, intravenous paracetamol and ibuprofen showed no statistically significant differences in short-term efficacy or safety when used as rescue therapy for hemodynamically significant patent ductus arteriosus in very preterm infants. The study demonstrated high feasibility but was not powered to determine clinical superiority or equivalence between treatments.

21 Jan 2026

Childhood ADHD traits linked to poorer physical health in midlife

People who have ADHD traits at age 10 are more likely than those without such traits to have physical health problems and to report physical health-related disability at age 46, according to a study led by University College London (UCL) and University of Liverpool researchers.

21 Jan 2026

NuSHs can be a promising therapeutic strategy for preventing MASH-related hepatocellular carcinoma

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), represent the most common chronic liver diseases in Western populations, driven largely by obesity and insulin resistance.

21 Jan 2026

Peer-supported clinic visits strengthen reproductive choices in rural India

Despite improvements in economic and social empowerment, women in many countries still have little control over their own fertility and reproductive health.

21 Jan 2026

Serum uric acid levels linked to atrial fibrillation burden

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study investigated the association between serum uric acid (UA) levels and atrial fibrillation (AF) burden in Chinese patients with AF.

21 Jan 2026

New review explores how stress uniquely affects children

Most research on the health effects of stress focuses on adults, but a new review looks at how stress uniquely affects children.

21 Jan 2026

Gambling disorder alters the brain's control and reward systems

A new doctoral dissertation shows that gambling disorder is linked to brain networks involved in self-control and brain reward functions.

21 Jan 2026

TGM2 as a novel biomarker for acute myocardial infarction and prognosis in acute coronary syndrome

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transglutaminase 2 (TGM2) has been implicated in various health conditions, yet its role in acute coronary syndrome (ACS) remains poorly characterized in clinical settings.

21 Jan 2026

Exercise-triggered mitochondrial transfer offers hope for stroke and dementia

Physical rehabilitation and symptom management still remain the mainstay of treatment for stroke, as clot removal or dissolution is effective only within a narrow time frame after the stroke.

21 Jan 2026

The neuroscience of motivation-driven memory retention

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and Duke University have proposed a neuroscience framework explaining how different types of motivation fundamentally reshape what and how the brain remembers.

21 Jan 2026

Mitotane’s role in the management of adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with high postoperative recurrence rates and poor prognosis. Mitotane remains the only approved agent for ACC, exerting antitumor effects by disrupting mitochondrial integrity, inhibiting steroidogenic enzymes, and interfering with cholesterol metabolism.

21 Jan 2026

Analyzing bacterial enzymes in pikromycin synthesis

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin infections.

21 Jan 2026

A dual-action approach to preventing hepatocellular carcinoma

Hepatocellular carcinoma is one of the leading causes of cancer-related death worldwide, largely due to its high rate of recurrence after surgery. Even after complete tumor removal, microscopic residual disease and early dissemination frequently lead to relapse within the first two years.

21 Jan 2026

Tracing the decline in American heart disease mortality

Following a five-year upward trend likely impacted by the COVID pandemic, the number of heart disease and stroke deaths has declined, yet, heart disease and stroke still kill more people in the U.S. each year than any other cause, according to data reported in the 2026 Heart Disease and Stroke Statistics: A Report of U.S. and Global Data From the American Heart Association.

21 Jan 2026

Cannabis legalization drives rising use among adults with historically lower consumption

A new study led by Boston College School of Social Work Professor Summer Sherburne Hawkins found that recreational cannabis legalization in the United States is driving increases in cannabis use among adults with historically lower consumption, as opposed to increasing use among those who already consumed cannabis.

21 Jan 2026

Mouse study reveals social hierarchy influences sleep quality during isolation

Researchers tested what factors improve or worsen the quality of sleep in mice. A team including researchers from the University of Tokyo placed mice in two environments, one where they could see and sense other mice without physical contact, and one in complete isolation.

21 Jan 2026

Arthritis significantly restricts employment for millions of American adults

According to new research from the University of Delaware, nearly 40% of American adults ages 18 to 64 with arthritis - almost 10 million people - say the medical condition is limiting their ability to work.

21 Jan 2026

Severe vitamin D deficiency linked to higher hospitalizations for respiratory tract infections

Severe vitamin D deficiency is associated with a higher rate of hospitalization for respiratory tract infections such as bronchitis and pneumonia, according to a new study led by the University of Surrey.

21 Jan 2026