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Long non-coding RNA MALAT1 linked to progression and spread of triple-negative breast cancer

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer's development or spread.

11 Nov 2025

Prior exposure to cold viruses boosts antibody response against SARS-CoV-2

Prior exposure to coronaviruses that cause ordinary colds can boost the immune system's ability to attack a vulnerable site on the COVID-19-causing coronavirus SARS-CoV-2, according to a study led by investigators at Weill Cornell Medicine.

11 Nov 2025

Daily coffee linked to lower risk of irregular heart rhythm episode in AFib patients

Adults treated for atrial fibrillation (AFib) who drank a daily cup of coffee were 39% less likely to have an irregular heart rhythm episode compared to those who avoided all caffeinated products, according to a new study.

11 Nov 2025

Amyloid-clearing drug fails to change waste clearance function in the brains of Alzheimer's patients

A group from Osaka Metropolitan University in Japan, led by graduate student Tatsushi Oura and Dr. Hiroyuki Tatekawa, found that treatment using the drug lecanemab to remove amyloid plaques in the brain does not change the waste clearance function in the brains of Alzheimer's disease (AD) patients in the short term.

11 Nov 2025

Study provides a new perspective for optimizing School Feeding Programs

School Feeding Programs (SFPs), as crucial public policies for improving children's nutrition and development globally, have covered 388 million children across 161 countries.

11 Nov 2025

Midlife blood test may reveal Alzheimer’s disease risk in advance

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy.

11 Nov 2025

Study offers an innovative way to track the spread of leishmaniasis

A new study offers an innovative way to track the spread of leishmaniasis, a parasitic disease affecting both animals and humans.

11 Nov 2025

Shared genetic roots connect neurological and psychiatric disorders

In a groundbreaking study, researchers from the Centre for Precision Psychiatry at the University of Oslo and Oslo University Hospital have discovered extensive genetic links between neurological disorders like migraine, stroke and epilepsy, and psychiatric illnesses such as schizophrenia and depression.

11 Nov 2025

Nanoparticle vaccine eliminates HPV-induced tumors in animal model

A nanoparticle vaccine designed to fight cancers induced by human papillomavirus (HPV) eradicated tumors in an animal model of late-stage metastatic disease, UT Southwestern Medical Center scientists report in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

11 Nov 2025

Study examines medication adherence in high-risk, low-income populations

People with high blood pressure were twice as likely to take their blood pressure medication regularly when offered daily chances to win cash rewards, yet they did not achieve better blood pressure measurements than people who were not offered financial rewards, a new study shows.

11 Nov 2025

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease.

11 Nov 2025

Tailored vitamin D regimens offer significant cardiac benefit

Adults with heart disease who had a previous heart attack and took vitamin D doses tailored to reach optimal blood levels reduced their risk of another heart attack by more than half compared to those who did not have their vitamin D blood levels optimized, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Metformin shows promise in treating AFib recurrence after ablation

People with atrial fibrillation (AFib) and obesity may have fewer episodes of AFib after ablation if they take the diabetes medication metformin in addition to standard care, according to a preliminary, late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Anticoagulants increase bleeding post-ablation with no added stroke benefit

A minimally invasive heart procedure to correct irregular heart rhythms called catheter ablation may reduce the risk of stroke enough that some patients can discontinue blood thinners, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Earlier blood transfusion reduces heart complications post-surgery in high-risk patients

An earlier blood transfusion- done when hemoglobin levels were higher - after major general or vascular surgery among people with heart disease was associated with a lower risk of some complications but not the most severe ones, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

One-month dual therapy strategy offers advantages for AFib patients and clinicians

New research found a simplified clot-preventing medication regimen following stent placement in adults with atrial fibrillation was just as safe and effective in preventing strokes, heart attack and death, when compared to a standard year-long treatment regimen, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Novel triple receptor agonist shows potent efficacy in lowering high triglycerides

In a small, short duration trial (12 weeks), a new medication called DR10624 reduced triglyceride levels in most patients with severe hypertriglyceridemia by more than 60%, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Preclinical study reveals dampened neuronal activity in alcohol-exposed mice

A psychedelic found in mushrooms is emerging as a potential treatment for alcohol use disorders. This possibility is due to a compound the body converts the psychedelic into called psilocin, but psilocin's mechanisms remain unclear.

11 Nov 2025

St. Jude study maps treatment strategy for rare infant gliomas

Clinician-scientists at St. Jude Children's Research Hospital and collaborators have conducted the largest study of infant-type hemispheric glioma (IHG) ever reported, uncovering key factors that could be used to guide treatment strategies for this rare pediatric brain tumor.

11 Nov 2025