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Age-related changes in the gut microbiota impair intestinal stem cell function

A new study led by Hartmut Geiger at the University of Ulm, Germany, and Yi Zheng and Kodandaramireddy Nalapareddy, Cincinnati Children's Hospital Medical Center (CCHMC), USA reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

22 Jan 2026

Researchers decipher a key mechanism that controls pancreatic cancer growth

Could this mark a shift in how we think about cancer therapy? At least in the laboratory, evidence suggests it may be.

22 Jan 2026

Short naps refresh the brain for better learning

Even a short afternoon nap can help the brain recover and improve its ability to learn. In a study published on January 22, 2026, in the journal NeuroImage, researchers at the Medical Center - University of Freiburg, Geneva University Hospitals (HUG) and University of Geneva, show that even a nap is enough to reorganize connections between nerve cells so that new information can be stored more effectively.

22 Jan 2026

Myosteatosis: An emerging predictor of outcomes in chronic liver disease

Myosteatosis, the pathological infiltration of fat into skeletal muscle, is increasingly recognized as a key predictor of poor clinical outcomes across a spectrum of liver diseases.

22 Jan 2026

High BMI linked to vascular dementia risk

High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular + unspecified dementia), according to new research from the University of Bristol and University Hospital of Copenhagen (Rigshospitalet and Herlev-Gentofte hospital).

22 Jan 2026

Researchers propose a new framework for understanding neutrophils

Researchers from Universidad Carlos III de Madrid (UC3M), the National Center for Cardiovascular Research (CNIC), and Yale University (USA) have published a comprehensive review article in the journal Cell that proposes a new framework for understanding neutrophils, the most abundant cells of the immune system.

22 Jan 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Regular aerobic exercise slows a key marker of brain aging in midlife

Regular aerobic activity significantly reduces brain-PAD, indicating that exercise is crucial for maintaining brain health and reducing dementia risk.

22 Jan 2026

Super-enhancers: Cancer's double-edged sword of growth and DNA damage

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive unusually intense gene activity.

22 Jan 2026

Lifelong health: The Northern Finland Birth Cohort 1966 enters a new era of aging research

One of the world’s most extensive birth cohorts is now entering later adulthood. At the University of Oulu in Finland, the Northern Finland Birth Cohort 1966 (NFBC1966) is launching a major new follow-up combining decades of biological, social, and environmental data with modern digital health tools to examine how lifelong exposures and the genome shape health and aging.

22 Jan 2026

Unlocking microbial secrets for health on Earth and beyond

Microorganisms live in biofilms - the equivalent of microbial "cities"- everywhere on Earth. These city-like structures protect and house microbial communities and play essential roles in enabling human and plant health on our planet.

22 Jan 2026

Study identifies a powerful strategy to overcome drug resistance in breast cancer

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6.

22 Jan 2026

Chemotherapy-induced gut changes trigger anti-metastatic immune response

Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to the gut.

22 Jan 2026

Bacteria behind Nagashima-type palmoplantar keratosis foot odor identified

The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the overgrowth of a specific bacterial strain.

22 Jan 2026

A routine blood test may reveal who is most at risk of osteoporosis

A routine creatinine blood test may identify individuals at higher risk for osteoporosis and fractures, highlighting its potential as a risk assessment tool.

22 Jan 2026

Large study identifies more than 100 genetic regions linked to schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

21 Jan 2026

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Overuse of antibiotics has accelerated the development of bacterial resistance to conventional drugs, a global health crisis projected to result in more than 10 million deaths annually by 2050.

21 Jan 2026

Understanding tumor growth patterns helps guide treatment after lung cancer

When lung cancer treatment stops working, what happens next? New research reveals the answer may depend on how the cancer grows.

21 Jan 2026

Reducing alcohol consumption could significantly lower cancer deaths

Reducing annual alcohol consumption in Australia by one litre a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.

21 Jan 2026

Study shows DHPS enzyme controls macrophage maturation across multiple organs

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

21 Jan 2026