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Evolutionary mutation weakens human immune response to solid tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

3 Jul 2025

Blocking key immune cells could make prostate cancer treatable

Scientists have revealed how certain immune cells may be quietly helping prostate cancer grow - and how blocking them could help the body fight back.

3 Jul 2025

EU researchers call for wider use of alternatives to animal testing

Researchers examine how the use of animal testing to identify endocrine-disrupting substances in the EU can be reduced. Although it is, in principle, possible to identify such substances without using animals, non-animal methods are still rarely applied.

3 Jul 2025

Anger traits decline with age in midlife women, study shows

There has been a lot of research focused on understanding women's experiences with depression during the menopause transition and early menopause, but there are few studies on perimenopausal women's experiences with emotional arousal, such as anger.

3 Jul 2025

Canada faces growing threat from communicable diseases and misinformation

Canada must address the growing crisis of communicable diseases that has occurred in tandem with a rise in misinformation that threatens our health systems, argue authors in an editorial in CMAJ.

3 Jul 2025

Youth facing isolation and low resilience at higher risk for adult anxiety and depression

Adolescents who experience both loneliness and low resilience are much more susceptible to developing anxiety and depression as adults.

3 Jul 2025

Breakthrough study questions longstanding STING activation approach

Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer.

3 Jul 2025

Lung cells generated from mouse embryonic fibroblasts in just 7 to 10 days

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology.

3 Jul 2025

Study reveals high rates of distracted driving among teenagers

A new study from Mass General Brigham researchers offers a stark reminder of how pervasive cell phone use while driving is among young people.

3 Jul 2025

Community vaccination program reduces pneumonia deaths among elderly in Japan

A research team has evaluated the real-world impact of a community-based pneumococcal vaccination support program for older adults conducted in Sera Town, Hiroshima Prefecture, Japan.

3 Jul 2025

Covid-19 impact extends beyond virus with increased deaths from other conditions

Disrupted care during the covid-19 pandemic led to sharp increases in other non-covid causes of illness and death, particularly mental health disorders, malaria in young children, and stroke and heart disease in older adults, finds a study published by The BMJ today.

3 Jul 2025

Gender differences shape how alcohol affects decision making

Alcohol consumption is widely known to affect decision-making, but a recent study led by researchers from The University of Texas at El Paso found that the extent of that impact may have something to do with the drinker's gender.

3 Jul 2025

Alzheimer’s protein found to drive lung cancer spread to the brain

Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain – a discovery that offers hope that existing Alzheimer's drugs could be repurposed in preventing cancer's spread.

3 Jul 2025

Perceived social status influences women’s cardiovascular risk

Women who see themselves as having lower social status are more likely than other people to show early signs of heart stress linked to future disease risk, according to a new study led by researchers at McGill and Concordia universities.

3 Jul 2025

Blood viral load predicts severity of mpox symptoms

In August 2024, the World Health Organization declared a second "Public Health Emergency of International Concern" for mpox.

3 Jul 2025

European study reveals barriers to multinational clinical trials

A new study by investigators from Europe, including the Netherlands and the United Kingdom (UK), has shed light on significant ethical, administrative, regulatory, and logistical (EARL) hurdles in delivering multinational randomized clinical trials.

3 Jul 2025

PPP2R1A mutations linked to improved survival in ovarian clear cell carcinoma

Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have improved survival following immunotherapy compared to patients without these mutations, according to researchers from The University of Texas MD Anderson Cancer Center.

3 Jul 2025