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Women with polyendocrine metabolic ovarian syndrome more likely to have Alzheimer's and dementia

Alzheimer's disease and dementia may be more common in women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS), according to a review of existing evidence published in the Journal of the Endocrine Society.

13 Oct 2026

Targeting the RUNX1 gene helps reduce severe skin fibrosis

Skin fibrosis includes hypertrophic scar (HTS), keloid scar (KS), and systemic sclerosis (SSc). These conditions share persistent fibroblast activation, excessive extracellular matrix (ECM) deposition, and progressive skin remodeling.

13 Oct 2026

Replacement chemical for harmful phthalates may restrict fetal growth

A chemical used to make plastic more flexible, once introduced as a safer substitute for older additives now known to be harmful, may itself also be harmful, slowing babies' growth in the womb, a new study shows.

13 Oct 2026

Exercise boosts psychological wellbeing for menopausal women

Engaging in physical activity during menopause can improve depression, mood and overall quality of life, a new study led by UCL researchers has found.

13 Oct 2026

Single-cell analysis reveals how pancreatic cancer evades treatment

An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.

13 Oct 2026

Switching to a vegan diet rapidly alters liver metabolism

A team from UNIGE has shown that switching from a vegetarian to a vegan diet is enough to modify the liver’s metabolism within a few days.

13 Oct 2026

Ensuring accessible work environments for disabled physicians may enhance patient care

New research indicates that 5% of practising physicians report a disability "always or often," and another 12% report disability "sometimes." The authors call for action on improving accessibility to ensure equity and sustainability in the physician workforce.

13 Oct 2026

Beyond ‘bad’ cholesterol: new clues to the risk of heart disease

Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level.

13 Oct 2026

Nearly 400,000 adults, six body measurements, and a surprising result for heart attack risk

A UK Biobank study involving 395,831 adults found that a higher body roundness index (BRI) was associated with an increased risk of myocardial infarction over a median follow-up of 13.3 years. BRI showed slightly better predictive performance than BMI and four other anthropometric measures, although the improvements were modest and require independent validation before clinical adoption.

13 Oct 2026

Concept Life Sciences appoints Dr Adrijana Vinter as Chief Executive Officer

We are pleased to announce the appointment of Dr Adrijana Vinter as Chief Executive Officer. Dr Vinter brings more than 20 years of experience spanning medicinal chemistry research, commercial development and executive leadership in the pharmaceutical and contract research industry sectors.

From Concept Life Sciences 13 Oct 2026

Gene therapy and special goggles help some blind adults detect objects again

In a phase 1 study of 10 adults with advanced retinitis pigmentosa, researchers found that optogenetic gene therapy combined with light-stimulating goggles was generally well tolerated, although one participant experienced a severe but transient ocular adverse event. Seven participants showed improved light sensitivity, while four of eight who completed behavioral testing demonstrated modest gains in visual function, providing preliminary evidence of partial vision restoration that requires confirmation in larger controlled trials.

12 Oct 2026

Scientists pinpoint key hotspot driving tau propagation in dementia

Diseases such as Alzheimer's and frontotemporal dementia are considered neurodegenerative tauopathies, in which tau proteins in the brain misfold and lead to cognitive decline.

12 Oct 2026

ADHD diagnoses rise as awareness improves across Europe, experts say

ADHD seems to be in the news everywhere, but is this due to a rise in cases or to changing awareness and diagnosis?

12 Oct 2026

Medical cannabis benefits for insomnia remain uncertain, Cochrane review finds

A new Cochrane review finds that existing evidence is too uncertain to determine whether medical cannabis improves sleep or daytime functioning in people with insomnia.

12 Oct 2026

Women with autoimmune diseases more likely to receive psychiatric misdiagnoses

Females with autoimmune diseases are significantly more likely than males to have their autoimmune disease misdiagnosed as a psychiatric or psychosomatic condition, according to a study of more than 6,600 patients.

12 Oct 2026

Long-term anabolic steroid use linked to lasting heart damage

Long-term use of anabolic-androgenic steroids (AAS) has serious consequences for the heart, according to a new study that has been following weightlifters for nearly 10 years.

12 Oct 2026

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms

In a phase 3 randomized clinical trial involving 410 people with early Parkinson disease, 52 weeks of nicotinamide riboside supplementation increased blood NAD levels but failed to improve clinical outcomes compared with placebo. Participants receiving the supplement had modestly worse overall disease scores, although the difference was below the threshold generally considered clinically meaningful.

12 Oct 2026

Your favorite song might make a needle prick hurt less

A study of 204 patients undergoing intravenous cannulation before MRI found that those listening to their favorite music reported significantly lower pain scores than patients hearing no music at 30 seconds and two minutes after puncture. Mozart was also associated with lower pain scores among patients with pre-existing pain, while relaxation music showed no significant benefit, although the non-randomized findings require confirmation.

12 Oct 2026

Study finds a surprising downside to having favourite foods

In a study of 279 adults, researchers found that initially reinforcing existing food preferences reduced learning flexibility when associations between foods and outcomes changed. Participants learned positive associations more readily than negative ones, while associations involving disliked foods were more adaptable than those involving liked foods.

12 Oct 2026

Who moves first at night, you or your dog?

Researchers monitored 25 adults and 38 dogs and found no significant association between bedsharing and objectively measured human sleep duration or efficiency, although owners of multiple dogs reported poorer sleep quality in an analysis requiring cautious interpretation. Human and dog movements were positively correlated, with human activity more often preceding canine activity among pairs with identifiable associations, although the study could not determine which species drove the other's movements.

12 Oct 2026