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Dysregulation of immune regulator NF-κB drives major human diseases

NF‑κB controls genes involved in inflammation, immunity, cell survival, and proliferation. Triggered by cytokines (TNF‑α, IL‑1β), microbial products, or cellular stress, it translocates to the nucleus and induces pro‑inflammatory mediators.

13 Jul 2026

New therapy targets Hippo pathway to fight treatment-resistant acute myeloid leukemia

Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid leukemia (AML) through activating the Hippo pathway, a tumor-suppressing pathway linked to cancer growth and drug resistance.

13 Jul 2026

Blocking ZFP384 protein extends brain repair window after stroke

Blocking the activity of ZFP384 can prolong the brain’s endogenous repair functions after stroke, report researchers in a collaborative study.

13 Jul 2026

Study reveals substantial rise in Latin American dementia rates

A new study led by researchers at Washington University School of Medicine in St. Louis and Newcastle University in the U.K. finds that the share of adults living with dementia rose substantially across several Latin American and Caribbean sites over the past two decades.

13 Jul 2026

Rising tick-borne disease in Canada can trigger heart inflammation

Move over, Lyme disease - there's another tick-borne disease to worry about in Canada. Anaplasmosis, the second most common tick-borne disease in the country, can cause a range of health issues, including myocarditis (inflammation of the heart muscle).

13 Jul 2026

Distinct gut microbiome signatures identify frailty in older women

Research reveals gut microbiome signatures linked to frailty in older women, highlighting microbial changes associated with mortality and physical decline.

13 Jul 2026

New study tracks early genetic changes in hepatitis E virus

Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability.

13 Jul 2026

Smelling dark chocolate before training may improve workout performance

Chocolate odors influence resistance exercise performance in fasted men, highlighting the potential of sensory cues to enhance training and appetite control.

13 Jul 2026

Animal-free lung model unlocks better treatments for RSV in babies

Future therapies for respiratory syncytial virus (RSV) must target both the virus and its immune response to ensure babies get the best possible outcomes, finds a new study by researchers at UCL and Great Ormond Street Hospital for Children (GOSH).

13 Jul 2026

Social media and low body esteem fuel cosmetic procedure addiction

As cosmetic procedures become increasingly normalized worldwide, new research suggests that for some women, repeated treatments may become addiction-like rather than purely cosmetic.

13 Jul 2026

Nearly one in 10 Britons use or want weight-loss medication

The prevalence of GLP-1 receptor agonists for weight management in Great Britain highlights public interest and concerns over safety and prescribing practices.

13 Jul 2026

Study links GLP-1 treatment to fewer alcohol drinking days

Current GLP-1 receptor agonist prescriptions were associated with modestly lower AUDIT-C scores in a large, diverse US cohort. The difference appeared to reflect less frequent drinking rather than fewer drinks per occasion or fewer binge-drinking episodes.

13 Jul 2026

Gut microbiota may shape eating behavior and guide new obesity treatments

The review shows how gut microbiota may influence appetite, food reward, inflammation, and energy balance through the gut-brain axis. Microbiota-targeted approaches could support future treatments for obesity and eating disorders, but clinical evidence remains limited.

12 Jul 2026

EGFR inhibitors may overcome chemotherapy resistance in glioblastoma treatment

Treating glioblastoma with a class of drugs known as EGFR inhibitors made this cancer more sensitive to chemotherapy, suggests a study in preclinical models co-led by researchers at UT Southwestern Medical Center and the University of Alabama at Birmingham.

12 Jul 2026

Gum disease bacteria linked to calcific aortic valve stenosis

Gum disease bacteria may spur calcium buildup in the heart's aortic valve, leading to a common and serious heart valve disease, according to preliminary, independent research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2026.

12 Jul 2026

Global study reveals country-specific patterns in dementia risk factors

A major, USC-led study of more than 214,000 older adults across 14 countries and regions finds that the most common controllable risk factors for dementia - such as low education, high blood pressure and smoking - vary widely from country to country, meaning a one-size-fits-all approach to prevention won't work everywhere.

12 Jul 2026

New benchmark shows AI still misses the human side of mental health care

PsyEval is a new benchmark that tests how large language models perform on mental health knowledge, diagnostic assessment, and emotional support tasks. The study found that leading models can show strong factual recall and fluent responses, but still struggle with empathy, clinical nuance, prompt sensitivity, and safe diagnostic behavior.

12 Jul 2026

Cold-exposed mothers pass metabolic protection to male rat offspring through milk

Maternal cold exposure during early pregnancy improved glucose control and reduced liver fat in male rat offspring, with benefits persisting into late adulthood. The findings implicate a breast milk LCA, gut microbiota, and Th17 immune pathway, while human cohort data showed an observational link between winter conception and lower MASLD risk.

12 Jul 2026

Rural radiation oncology clinic closures threaten cancer patient care

A new study led by researchers at the Icahn School of Medicine at Mount Sinai found that although the overall number of radiation oncology clinics in the United States has appeared stable in recent years, many individual treatment centers have quietly closed while others have opened.

11 Jul 2026

New stem cell approach targets functional cure for diabetes

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.

11 Jul 2026