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New mechanism behind chemotherapy resistance in ovarian cancer discovered

Scientists at The Wistar Institute have identified a new mechanism behind the chemotherapy resistance that makes ovarian cancer so lethal.

23 Jul 2026

Lifestyle changes improve MASLD by suppressing key molecular pathway

Lifestyle modification is the cornerstone of managing metabolic dysfunction-associated steatotic liver disease (MASLD), a growing cause of chronic liver disease worldwide.

23 Jul 2026

Compact genetic switch enables targeted gene therapy for epilepsy

Epilepsy affects over 50 million people worldwide, making it one of the most common neurological disorders.

23 Jul 2026

Study reveals unexpected mechanism driving extreme antibiotic resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

23 Jul 2026

Proactive telehealth program helps cancer patients quit smoking

For patients diagnosed with cancer, continuing to smoke during treatment may shorten survival.

23 Jul 2026

New bacterial control strategy helps revive failing last-line antibiotics

Antimicrobial resistance is one of the world's most alarming public health challenges, because the multidrug-resistant (MDR) gram-negative bacteria increasingly render even last-line antibiotics ineffective, leading to substantially higher mortality rates.

23 Jul 2026

Short-term immunosuppressive therapy briefly restores autism-like brain changes in adult mice

A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but also that those brain and behavior effects may be rapidly but temporarily reversible in adulthood with a short-term dose of the immunosuppressive drug rapamycin.

23 Jul 2026

Emerging PPAR therapies offer new hope for primary biliary cholangitis

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.

23 Jul 2026

Dormant melanocytes found in vitiligo offer hope for future repigmentation therapies

Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease.

23 Jul 2026

Study reveals regional disparities in Brazilian childhood leukemia mortality

An international study involving LMU found regional differences in childhood lymphoid leukemia mortality across Brazil.

23 Jul 2026

Study finds greater social jetlag linked to a later eating pattern

In a 14-day study of 101 healthy UK adults, greater social jetlag was associated with a later distribution of energy intake, particularly greater late-evening intake among women. The effects were modest, varied by sex and day type, and did not establish whether total daily energy intake differed between groups.

23 Jul 2026

Ancient immune protein C3 boosts cancer immunotherapy within tumors

An ancient molecule that existed long before the blood circulation system evolved, has been found to support cancer immunotherapy.

23 Jul 2026

Spermidine boosts key cellular processes linked to aging in early research

This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved.

23 Jul 2026

Thymulin curbs age-related inflammation and slows breast tumors in mice

Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB signaling. The peptide also restored anti-PD-L1 responsiveness in aged mouse models, while human cell and tumor data supported an age-linked inflammatory myeloid profile.

23 Jul 2026

Study reveals bacterial strategy behind antibiotic tolerance and persistence

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.

22 Jul 2026

Multiple sclerosis mortality trends underscore need for comprehensive patient care

An analysis of more than 42,000 U.S. deaths linked to multiple sclerosis (MS) found that death rates varied by age, geography, and race and ethnicity, with Black patients dying younger than white patients and high blood pressure emerging as a growing contributor.

22 Jul 2026

Stuffed toys can release short-chain PFAS into saliva, study finds

Researchers tested 18 stuffed toys and found that all released at least one targeted PFAS into artificial saliva under mouthing-relevant conditions, with PFHxA driving much of the variation between products. Modeled intake of the four PFAS covered by EFSA’s group tolerable weekly intake remained below that benchmark, but some high-PFHxA toys had reduced margins of exposure, and water rinsing produced mixed results.

22 Jul 2026

Prolactin activates brain pathway promoting maternal caregiving behavior

New research has found a hormone is responsible for making mothers' interactions with newborns feel rewarding rather than just necessary.

22 Jul 2026

DNA enhancer hubs control cancer genes in prostate tumors

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

22 Jul 2026

SuperAgers retain exceptional memory through mechanisms beyond genetics

Many people assume that some memory decline is an inevitable consequence of getting older. But a select group of older adults, known as SuperAgers, reach their 80s and 90s while retaining memory performance as good as or better than people in their 50s and 60s.

22 Jul 2026