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BMI may miss millions with obesity-related conditions

Could the way doctors traditionally measure obesity allow a subset of people with obesity-related health risks slip through the cracks?

1 Jun 2026

Jumping genes help strengthen the mammalian Y chromosome

The humble Y chromosome may be the smallest chromosome in the mammalian genome (and getting even smaller), but it is mighty: genes on the Y chromosome are critical for fertility in males.

1 Jun 2026

Antibiotic-free therapy seeks to prevent newborn meningitis by blocking E. coli

Newborn meningitis is one of the most dangerous childhood infections. It is often life-threatening and can cause serious and lasting damage, including developmental problems, in the children who survive.

1 Jun 2026

PromptSE AI predicts drug side effects by reasoning through biological clues

PromptSE uses structured LLM prompting to generate pharmacologically relevant side-effect representations, then feeds them into deep learning models to predict drug-side effect associations. In benchmark testing, PromptSE improved prediction performance, while PromptSE+ further boosted results by adding multi-modal drug information and graph-based refinement for sparse data.

1 Jun 2026

Genetic testing finds breast cancer risks that standard screening models miss

Population-based pathogenic variant testing identified breast cancer susceptibility gene carriers who would often be missed by clinical risk models, even when polygenic risk scores were added. In the WISDOM Study analysis, fewer than 1% of high-penetrance variant carriers would have received the same high-risk screening recommendation using clinical plus polygenic risk alone.

1 Jun 2026

Brazilian study links TP53 mutations to poor lung cancer prognosis

Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity.

1 Jun 2026

Mature intestinal cells regain stem cell behavior to trigger tumor growth

In a groundbreaking study, Stevens researchers show how colorectal cancers can evolve from mature intestinal cells that revert to stem cells.

1 Jun 2026

Study shows how HIV leads to chronic pain

Over half of the people carrying HIV experience chronic pain at some point, which is difficult to treat. In a new JNeurosci paper, Hui-Lin Pan, from The University of Texas MD Anderson Cancer Center, and colleagues used mice to explore how HIV leads to chronic pain.

1 Jun 2026

Targeting microRNA pathway helps overcome cancer immunotherapy resistance

Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment.

1 Jun 2026

Pediatric influenza vaccination effectively protects young children

Pediatric flu vaccines significantly reduce the number of childhood cases of influenza, new research from Harvard Medical School confirms.

1 Jun 2026

People with high autistic traits face worsening anxiety in older age

A major UK study has found that while most middle-aged and older adults experience low levels of anxiety, a small group of people with higher autistic traits are much more likely to report that their anxiety worsens as they age.

1 Jun 2026

Study evaluates statistical models for estimating breast cancer risk

Researchers from Trinity College Dublin, St James's Hospital, and collaborating institutions have carried out the most comprehensive review to date of tools used to estimate breast cancer risk in women with a family history of the disease.

1 Jun 2026

Vaccine and drug combination cuts melanoma recurrence by half

The combination of a vaccine and a drug, which both harness the immune system to attack cancer cells, has proven successful in cutting the risk of skin cancer recurrence by 49 percent, a new study shows.

1 Jun 2026

Understanding mitochondrial biology in alcohol-associated liver disease and cancer

For decades, giant mitochondria-known as megamitochondria-have been recognized in liver biopsies from patients with alcohol-associated liver disease (ALD).

1 Jun 2026

Healthy lifestyles reduce cardiovascular risks for childhood cancer survivors

Healthy lifestyles can reduce the risk of cardiovascular disease and other complications in childhood cancer survivors.

1 Jun 2026

Post-discharge oral antibiotics show no benefit for pediatric appendicitis

Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization.

1 Jun 2026

Moderate-to-vigorous physical activity boosts middle-age mental health more than walking

Moderate-to-vigorous physical activity is more important for mental health in middle age than light physical activity, according to a new study by the University of Oulu and ODL Department of Sports and Exercise Medicine.

1 Jun 2026

Weight loss drugs could widen health inequalities without nutritional support

Drugs such as semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro) are transforming obesity treatment, but without affordable, healthy food and appropriate support, they could widen health inequalities in the UK, according to researchers at UCL and the University of Cambridge.

1 Jun 2026

Bariatric surgery improves long-term ability to manage household tasks

People who undergo bariatric surgery and see substantial weight loss are better able to cope with household tasks such as cleaning, laundry and grocery shopping.

1 Jun 2026

Laverock Therapeutics awarded in excess of £2.2 M through two innovation grants to support AI-powered platform development and to expand therapeutic programs outside of oncology

Laverock Therapeutics ('Laverock'), a biotechnology company developing disease-responsive advanced therapies through its unique, programmable gene control technology, today announced it has been awarded two new grants totaling in excess of £2.2 M to support the next generation of its gene-control platform development, and expansion into additional non-oncology therapeutics areas.

From Laverock Therapeutics 1 Jun 2026