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CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

New national dataset maps how far Australians must drive to reach essential healthcare services

Researchers created a nationally consistent, publicly available dataset estimating car-based driving times and distances to key healthcare services across Australia using mesh block–level data. The dataset reveals substantial geographic variation in access, particularly in regional and remote areas, and provides a standardized foundation for future health services research.

23 Dec 2025

High-fat cheese and cream consumption links to lower dementia risk over 25 years

Higher intake of high-fat cheese and cream was associated with a lower risk of all-cause dementia over 25 years in a large Swedish cohort, while low-fat dairy showed no association. Associations were strongest for vascular dementia and among APOE ε4 non-carriers, with findings remaining observational.

23 Dec 2025

Study demonstrates significant changes in gut bacteria at the onset of IBD

Patients experience significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a new international study has found - offering new hope for earlier diagnosis and future treatments.

23 Dec 2025

Neuronal master switch reshapes brain activity during learning

Memories and learning processes are based on changes in the brain's neuronal connections and, as a result, in signal transmission between neurons.

23 Dec 2025

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

A team led by clinicians and engineers has wrapped the plant-derived polyphenol pterostilbene (PSB) into prebiotic alginate/resistant-starch microcapsules coated with chitosan and shown that oral administration dampens dextran-sulfate-sodium (DSS) colitis in mice.

23 Dec 2025

Researchers explore a promising approach to enhance the immune system's ability to fight cancer

Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new treatments.

23 Dec 2025

Marijuana use associated with worse school performance and emotional distress for teens

Using marijuana just once or twice a month was associated with worse school performance and emotional distress for teens, according to a large national study of adolescents led by Ryan Sultán, an assistant professor of clinical psychiatry at Columbia University Vagelos College of Physicians and Surgeons.

23 Dec 2025

Spatial computing explains how the brain organizes cognition

Our thoughts are specified by our knowledge and plans, yet our cognition can also be fast and flexible in handling new information.

22 Dec 2025

Menopause hormone therapy not linked to dementia risk in women

A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.

22 Dec 2025

THC products provide small improvements in pain but carry side effects

A new systematic evidence review finds that cannabis products that carry relatively high levels of the psychoactive compound tetrahydrocannabinol, commonly known as THC, may provide short-term improvements in pain and function.

22 Dec 2025

Early brain connectivity predicts recovery after traumatic brain injury

After traumatic brain injury (TBI), some patients may recover completely, while others retain severe disabilities.

22 Dec 2025

Reframing the role of MCL1 in cancer signaling and metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology.

22 Dec 2025

A senescence-based therapeutic approach for temporal lobe epilepsy

Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells.

22 Dec 2025

Research highlights a potential therapeutic strategy for vascular dementia

A possible new treatment for impaired brain blood flow and related dementias is on the horizon.

22 Dec 2025

Altered stress signaling helps explain relapse in alcohol use disorder

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.

22 Dec 2025

Precision immunotherapy for TRBC2-positive T-cell malignancies

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors.

22 Dec 2025

Fatty diets reprogram hepatocytes and increase liver cancer risk

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.

22 Dec 2025

Rethinking Mendelian assumptions in inherited retinal degenerations

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

22 Dec 2025

Remodeling the tumor microenvironment to unlock CAR-T cell potential

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor microenvironment (TME).

22 Dec 2025