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Why different loneliness tests still identify the same emotional struggles

Researchers examined how loneliness classifications, by frequency, distress, or chronicity, relate to cognitive and behavioral traits in 790 adults. Despite modest agreement between classification methods, the study found consistent psychological patterns among lonely individuals across all types of loneliness.

29 Apr 2025

Measles makes a deadly comeback in Europe as vaccine gaps widen

In 2024, measles cases in Europe soared to the highest levels in decades, with over 35,000 reported cases, 87% from Romania alone. Most affected were unvaccinated children, revealing critical immunity gaps and suboptimal vaccination coverage across the EU/EEA.

29 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

Tailored treatment guided by dual biopsy approach may improve outcomes for patients with advanced cancers

Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy based on the detection of the same genomic alteration in both tissue and liquid biopsies compared with both standard-of-care treatment and tailored therapy that was based on either biopsy on its own, according to results from the phase II, multicenter ROME trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Cancer-related fatigue and depression found to limit recreational activities in survivors

Cancer survivors who reported feeling cancer-related fatigue or depression reduced their recreational activities nearly twofold, with females more likely than males to report feeling either cancer-related fatigue or depression, according to a retrospective study presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance of intratumoral microbiota-microbiota inside tumors-in CRC progression.

29 Apr 2025

Genetic predisposition to muscle strength linked to lower cardiovascular mortality

A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, found that men with a genetic predisposition supporting higher muscle strength had a lower risk of dying from cardiovascular diseases, regardless of their leisure-time physical activity levels or other lifestyle-related factors.

29 Apr 2025

New compounds identified as inhibitors of DNA topoisomerase 1

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA.

29 Apr 2025

Intimate relationships may shield against cognitive decline during chemo

A satisfying intimate relationship may help diminish chemotherapy-related cognitive problems experienced by patients with breast cancer, a new study suggests.

29 Apr 2025

Teen depression may offer better treatment opportunities with flexible symptoms

Depression in young teens could be easier to treat than in adulthood due to the symptoms being more flexible and not yet ingrained, a study shows.

29 Apr 2025

Researchers uncover how substance use accelerates brain aging

In a comprehensive Genomic Press Interview, researchers from UTHealth Houston have uncovered crucial evidence that substance use disorders (SUDs) accelerate biological aging in the brain through distinct molecular mechanisms.

29 Apr 2025

Synthetic tau protein reveals key insights into protein misfolding and fibril formation

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion.

29 Apr 2025

Researchers discover new biomarker to predict multiple sclerosis progression

Researchers at the University of Turku, Finland, have discovered a new biomarker that can predict the progression of multiple sclerosis (MS).

29 Apr 2025

Perceived stress linked to worsened symptoms in COPD patients

Increased perceived stress may cause worsened respiratory symptoms and decreased quality of life in people with chronic obstructive pulmonary disease (COPD), according to a new study.

29 Apr 2025

‘Game-changer’ clinical trial launches for Australia’s second-deadliest cancer

A world-first clinical trial launched in Melbourne is being hailed a ‘game-changer’ for its potential to revolutionize the way people with bowel cancer are treated.

29 Apr 2025

How blood iron levels shape the pace of biological aging

Researchers examine the role of blood iron levels in DNA methylation-based measurements of biological aging.

29 Apr 2025

Hormone therapy boosts heart health markers but raises some risks

Researchers assess hormone therapy-induced changes in cardiovascular biomarkers.

29 Apr 2025

Pecans lower cholesterol and improve diet quality in at-risk adults, study finds

Substituting 57 grams of pecans for usual snacks over 12 weeks improved lipid profiles and diet quality but did not affect vascular function in adults at cardiometabolic risk. A modest weight gain was also observed.

29 Apr 2025

PET scans reveal early signs of Parkinson’s and Lewy body disorders

In a comprehensive Genomic Press perspective article published today, researchers from Fudan University and Shanghai University of Traditional Chinese Medicine have highlighted remarkable advances in the development of positron emission tomography (PET) tracers capable of visualizing α-synuclein aggregates in the brains of patients with Parkinson's disease and related disorders.

29 Apr 2025