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Quotient Sciences proprietary AI-enhanced solution optimizes formulation in clinical study

Quotient Sciences, a global integrated CRDMO (contract research, development and manufacturing organization), today reported interim results from a clinical study in which a proprietary artificial intelligence (AI) algorithm selected modified-release formulation compositions and doses during the trial.

From Quotient Sciences 18 Sep 2026

Better fitness was linked to healthier brain structure, but not better memory

Researchers studying 353 cognitively unimpaired adults aged 60 to 94 found that higher muscular capacity was associated with lower basal ganglia perivascular space volume, while greater aerobic fitness was associated with greater gray matter volume and medial temporal lobe thickness. Fitness was not directly associated with global cognition or episodic memory, and evidence for cognitive reserve was limited, although VO₂max explained additional variation in delayed verbal memory beyond tau burden.

18 Sep 2026

Study identifies two opposing molecular patterns in autism models

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms?

17 Sep 2026

Sex-specific biological clocks reveal how aging differs across the body in women and men

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.

17 Sep 2026

Exercise-based cardiac rehabilitation offers lasting heart health benefits

Exercise-based cardiac rehabilitation reduces hospital admissions by a third and heart attack risk by more than a quarter, as well as remaining beneficial in the long term, a new Cochrane review finds.

17 Sep 2026

Eight-weekly HIV injections prove more effective than daily tablets for young people

Young people living with HIV manage their condition better when their antiretroviral therapy is given by injections every eight weeks, rather than in the form of daily tablets, according to the results of a trial in Africa led by UCL (University College London) researchers.

17 Sep 2026

Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide

Researchers combined toxin sequence mining with machine learning and deep-learning prediction tools to identify and experimentally test 14 antimicrobial peptide candidates derived from cobra cardiotoxins. Most candidates showed limited antibacterial potency, while CTX-p5 displayed moderate membrane-disrupting activity, revealing both the potential and current limitations of computationally guided venom peptide discovery.

17 Sep 2026

Being active may not tell the whole story when it comes to weight gain

A five-year study of 2,606 young and early-midlife Finnish municipal employees examined how leisure-time physical activity and sedentary behavior were associated with gaining at least 10% of baseline body weight. About 24% of women and 12% of men experienced major weight gain, with the analysis pointing to the importance of considering activity and sedentary time together.

17 Sep 2026

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

A large Australian randomized trial of 2,137 pregnant women tested whether substantially increasing egg and peanut consumption during pregnancy and breastfeeding could prevent food allergy in infants with a strong family history of allergic disease. Higher maternal intake did not significantly reduce IgE-mediated egg or peanut allergy at 1 year, although the lower-than-expected allergy rate limited statistical power and the results could not exclude a clinically important benefit.

17 Sep 2026

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

17 Sep 2026

Study identifies powerful inherited risk factor for lung cancer

A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research Institute.

17 Sep 2026

Social media posts misrepresent Alzheimer's blood test recommendations

Researchers have raised concerns about the promotion of Alzheimer's disease blood tests on social media, particularly posts making claims that do not align with current clinical recommendations.

17 Sep 2026

Study highlights drop in harmful medication use among adults with cognitive disorders

Adults 65 and older with cognitive disorders such as dementia, are more likely to suffer negative effects from drugs that treat central nervous system conditions including anxiety, sleep problems and psychosis.

17 Sep 2026

Maternal depressive symptoms linked to higher infant mortality risk

Infants born to mothers with depressive symptoms immediately after delivery had a substantially higher risk of dying before their first birthday, according to researchers involved in a Rutgers-led study of more than 414,000 births in New Jersey.

17 Sep 2026

ACC Latin America 2026 studies highlight sex and regional disparities in heart attack care

disparities in ST-segment elevation myocardial infarction (STEMI) management and outcomes across Latin America, focusing on women as a higher risk, yet underrepresented, patient group.

17 Sep 2026

US health officials knowingly relied on flawed vaccine safety algorithm

US health officials knowingly relied on a compromised algorithm to detect signals of harm from mRNA covid-19 vaccines and silenced efforts to fix it, finds an investigation published by The BMJ today.

17 Sep 2026

Weill Cornell Medicine receives $17.4 million grant to shorten tuberculosis treatment

Researchers at Weill Cornell Medicine have received a $17.4 million, five-year grant from the National Institute of Allergy and Infectious Diseases to discover new approaches to shorten tuberculosis (TB) treatment, potentially making it easier for patients to complete therapy.

17 Sep 2026

Medical Research News

Quotient Sciences proprietary AI-enhanced solution optimizes formulation in clinical study

Better fitness was linked to healthier brain structure, but not better memory

Study identifies two opposing molecular patterns in autism models

Sex-specific biological clocks reveal how aging differs across the body in women and men

Exercise-based cardiac rehabilitation offers lasting heart health benefits

Eight-weekly HIV injections prove more effective than daily tablets for young people

Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide

Being active may not tell the whole story when it comes to weight gain

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

Study identifies powerful inherited risk factor for lung cancer

Social media posts misrepresent Alzheimer's blood test recommendations

Study highlights drop in harmful medication use among adults with cognitive disorders

Maternal depressive symptoms linked to higher infant mortality risk

ACC Latin America 2026 studies highlight sex and regional disparities in heart attack care

US health officials knowingly relied on flawed vaccine safety algorithm

Weill Cornell Medicine receives $17.4 million grant to shorten tuberculosis treatment

Celastrol reduces cholestatic liver injury by inhibiting specific protein

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Deafness prompts brain rewiring to enhance peripheral vision

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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