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Blood protein structure changes may enable earlier detection of Alzheimer’s

Advanced proteomics and AI reveal blood protein changes, offering insights into early Alzheimer's detection and differentiation from mild cognitive impairment.

13 Mar 2026

Using blood proteins to make living brains transparent

Making a living brain transparent and watching its neurons fire without disturbing their function-sounds like science fiction, doesn't it? Yet the solution may already exist within our own bodies.

13 Mar 2026

Predicting cancer behavior through splicing fingerprints

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Kyoto University unveils noninvasive assessment for diabetes

In type 1 diabetes, the immune system starts to destroy insulin-producing beta cells in the pancreas. Progressive loss of these cells destabilizes the body's glucose levels and drives the course of the disease, so preserving or restoring beta cell mass is a central treatment goal.

13 Mar 2026

Cambridge’s LED breakthrough reinvents drug synthesis

Scientists at the University of Cambridge have developed a new way to alter complex drug molecules using light rather than toxic chemicals – a discovery that could accelerate and improve how medicines are designed and made.

13 Mar 2026

Study finds cockroach allergy often driven by shared proteins across arthropods

Researchers analyzed molecular sensitization patterns in Polish patients with perennial allergic rhinitis who tested positive for cockroach allergens. They found that most apparent cockroach allergies were driven by cross-reactive proteins shared with mites, seafood, and other arthropods rather than true cockroach-specific allergens.

13 Mar 2026

Defining the limits of immunotherapy in early small-cell lung cancer

Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer (SCLC) according to the results of an international clinical trial, NRG-LU005, led by NRG Oncology in collaboration with the Alliance for Clinical Trials in Oncology. The results are published in the Journal of Clinical Oncology.

13 Mar 2026

NUS uncovers NuSAP’s role in centriole stability

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental disorders such as microcephaly and mosaic variegated aneuploidy (MVA) syndrome.

12 Mar 2026

Swapping red meat for plant-based meat rapidly lowers a key heart risk metabolite, trial finds

A randomized crossover trial found that replacing red meat patties with processed plant-based meat alternatives for six days significantly lowered circulating trimethylamine N-oxide (TMAO), a gut-derived metabolite linked to cardiovascular risk. The plant-based phase also produced modest reductions in cholesterol markers but slightly increased weight and NT-proBNP, possibly due to higher sodium intake.

12 Mar 2026

Lifelong tracking of fish reveals early behavioral signals of aging

Scientists tracking the entire life of the African turquoise killifish have discovered that behavior alone can predict whether an animal will live a long or short life.

12 Mar 2026

Gut microbes may drive memory decline during aging by disrupting vagal brain signaling

Researchers identified in mice a microbiome–gut–brain pathway in which age-associated changes in gut microbes increase medium-chain fatty acids that impair vagal sensory signaling and hippocampal activity. These interoceptive disruptions weaken memory formation, revealing a microbial mechanism that contributes to cognitive decline during aging.

12 Mar 2026

Study reveals racial differences in early Alzheimer's brain changes

A team of researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has identified important differences in how early Alzheimer's disease-related brain changes appear across racial and ethnic groups, underscoring the need for more inclusive approaches to studying and diagnosing the disease.

12 Mar 2026

Experimental therapy eliminates pancreatic precancerous cells in mice study

A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.

12 Mar 2026

Scientists uncover unexpected cancer target on tumor cell surfaces

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

12 Mar 2026

Google’s AI medical assistant shows doctor-level diagnostic reasoning in real clinic study

A prospective feasibility study in an urgent care clinic tested a conversational AI system (AMIE) with 100 real patients to evaluate whether it could safely collect medical histories before doctor visits. The supervised AI showed no safety stops, produced diagnostic reasoning comparable to clinicians in blinded reviews, and improved patients’ attitudes toward medical AI.

12 Mar 2026

Real-world study shows modest weight regain after GLP-1 discontinuation

As the use of injectable GLP-1 drugs continues to rise, questions persist about what happens after patients stop taking them in real-world settings.

12 Mar 2026

Topical cream activates immune response to suppress skin cancer growth

A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous squamous cell carcinoma (cSCC), one of the most common cancers in the world, according to a study published today in the Journal of Clinical Investigation.

12 Mar 2026